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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Seven Counties Services
Shepherdsville, KY

Seven Counties Services, situated in Shepherdsville, KY, delivers a complete suite of recovery initiatives for adults and young adults confronting addiction and coexisting mental health challenges. Their offerings include robust outpatient care, general outpatient support, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Employing proven methods such as 12-step support, motivational interviewing, and cognitive behavioral therapy, the center customizes care to each person's unique journey. They also feature distinct programs for men and women, acknowledging the importance of gender-specific support for improved healing. Seven Counties Services is dedicated to high-quality, individualized recovery, positioning it as a reliable option for those in search of effective rehabilitation.

Seven Hills Hospital

At Seven Hills Hospital, located in Henderson, NV, we provide extensive support for individuals of all ages grappling with substance abuse and intertwined mental health challenges. Our services encompass inpatient detoxification and therapeutic care within a hospital setting. We employ proven methods such as 12-step facilitation, anger management techniques, and brief intervention strategies. Seven Hills Hospital is distinguished by its specific treatment tracks for active military personnel, teenagers, and adult men, catering to the unique needs of various groups. Recognizing the importance of tailored care, we offer distinct programs for both male and female patients, fostering an individualized and encouraging atmosphere. Choose Seven Hills Hospital for dependable, high-quality rehabilitation and recovery.

Seymour Comprehensive Treatment Center

Seymour Comprehensive Treatment Center, located in Seymour, IN, specializes in outpatient treatment programs for adults and young adults dealing with substance use issues. The center offers treatments with medications such as methadone, buprenorphine, or naltrexone in conjunction with ongoing outpatient support. By employing techniques like 12-step facilitation, motivational interviewing, and relapse prevention, the facility emphasizes customized recovery methods. It provides distinct programs catering specifically to male and female clients, ensuring that individuals receive the care and guidance they need to tackle addiction. For those in pursuit of a thorough and tailored treatment path, this center is committed to supporting you on your path to recovery.

Shalom Healthcare Center
Indianapolis, IN

Shalom Healthcare Center, located in Indianapolis, IN, provides outpatient treatment for substance use disorders, prioritizing individuals with co-existing mental health issues in adults and emotional challenges in children. The center offers tailored outpatient options, including methadone, buprenorphine, or naltrexone therapy, alongside standard outpatient services. Their treatment modalities encompass techniques like anger management, brief interventions, and cognitive behavioral therapy. With a personalized approach, the facility serves both male and female adults and young adults. Shalom Healthcare Center is committed to offering exceptional care that is customized to the unique needs of each individual, establishing itself as a compassionate and effective option for those in need of thorough rehabilitation services.

Shanti Recovery and Wellness

Situated in Portland, OR, Shanti Recovery and Wellness delivers extensive outpatient rehabilitation services for both adults and children. Focusing on substance use disorders, the center also addresses accompanying mental health issues. With programs designed for military personnel, teenagers, and adult males, Shanti Recovery and Wellness utilizes proven methods such as cognitive behavioral therapy and motivational interviewing. The center provides personalized outpatient treatments with methadone/buprenorphine or naltrexone to cater to individual recovery needs. Committed to offering excellent, tailored care for all clients, this center aims to foster enduring health and recovery.

Sharp Mesa Vista Hospital

Sharp Mesa Vista Hospital, situated in San Diego, California, is a premier facility dedicated to comprehensive care for individuals undergoing detoxification and addressing substance use challenges. This center is particularly adept at supporting patients who are also managing co-occurring mental health conditions. Offering structured inpatient programs designed for adults and seniors, the hospital provides round-the-clock support within a medical environment. Sharp Mesa Vista Hospital employs scientifically validated methods, including 12-step program integration, techniques for managing anger, and short-term therapeutic interventions, to foster successful recovery. The facility is equipped to serve both male and female patients, establishing itself as a reliable provider of high-quality rehabilitation.

Sharehouse Grand Forks
Grand Forks, ND

Sharehouse Grand Forks, located in Grand Forks, ND, delivers extensive programs for individuals struggling with substance abuse and co-occurring serious mental health conditions. They serve adults and young adults, offering various care durations including extended, brief, and round-the-clock residential options. Their therapeutic methods are rooted in proven techniques such as 12-step recovery support, emotional regulation skills, and cognitive behavioral strategies. The center has tailored services designed for adult men, adult women, and those with a history of trauma. Emphasizing personalized treatment plans, Sharehouse Grand Forks is dedicated to providing effective recovery support for both men and women facing addiction and mental health concerns.

Seven Counties Services
Taylorsville, KY

Seven Counties Services, located in Taylorsville, KY, specializes in outpatient treatment for adults facing substance use challenges alongside significant mental health disorders. The center employs various therapeutic methods, including 12-step facilitation and cognitive behavioral therapy, ensuring a high level of care through consistent outpatient appointments. With dedicated programs for both adult men and women, in addition to offerings for younger adults, the facility accommodates a wide array of needs. Seven Counties Services distinguishes itself with its thorough and individualized strategy to addiction recovery, positioning itself as a preferred option for individuals in search of effective and empathetic rehabilitation support.

ShareHouse Inc

ShareHouse Inc, located in Fargo, ND, delivers extensive programs for addiction recovery and supportive living accommodations. This establishment focuses on tailored care for adults facing dual diagnoses of substance abuse and significant mental health challenges, alongside emotional difficulties in youth. Their offerings encompass intensive outpatient, day treatment, and standard outpatient care. ShareHouse Inc utilizes proven methods including 12-step guidance, strategies for managing anger, and short-term interventions. Primarily serving adults and young adults of any gender who have co-occurring conditions or legal entanglements, ShareHouse Inc is dedicated to providing top-tier assistance and resources for those pursuing lasting sobriety and personal growth.

Seven Counties Services

Seven Counties Services, located in Louisville, KY, provides extensive treatment for substance use issues and transitional housing specifically for men. This center excels in addressing both co-occurring substance use and significant mental health disorders in adults, along with severe emotional problems in children. Adopting methods such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, the facility ensures top-notch care within a residential environment. It serves a range of clients, including adults, seniors, and young adults, though it is exclusively for male individuals. Featuring both short-term and around-the-clock residential options, Seven Counties Services is committed to aiding individuals on their journey toward recovery.

Seven Counties Services

Seven Counties Services, located in Louisville, KY, provides an extensive array of treatment options for both adults and young adults facing challenges related to substance use disorders, as well as co-existing mental health issues. This center features specialized programs catering to adult men, adult women, and individuals involved in the criminal justice system. They offer inpatient detoxification and treatment grounded in evidence-based practices including 12-step facilitation, cognitive behavioral therapy, and brief interventions. Committed to delivering high-quality care, Seven Counties Services focuses on personalized programs to address the unique needs of various age groups and genders, striving to support individuals on their journey toward lasting recovery and enhanced mental well-being.

Shalom Healthcare Center
Indianapolis, IN

Shalom Healthcare Center in Indianapolis, IN, provides specialized outpatient services for individuals of all ages struggling with substance use and dual diagnoses. Their offerings include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. They also implement targeted therapeutic interventions such as anger management, brief counseling, and cognitive behavioral therapy. This center is dedicated to creating customized recovery plans for adults and young adults, emphasizing a holistic and personalized path toward healing.

ShareHouse Inc

ShareHouse Inc, situated in Fargo, ND, specializes in comprehensive care for adult men struggling with addiction and co-occurring mental health challenges. They provide both extended and brief residential stays, utilizing proven methods such as cognitive behavioral therapy and anger management. ShareHouse Inc is equipped to support individuals with a history of trauma, ensuring a secure and nurturing space for healing. Their approach includes strong emphasis on 12-step principles, offering complete services for adults, older adults, and younger adults. For individuals desiring a structured, gender-specific recovery program, ShareHouse Inc is committed to delivering exceptional, personalized treatment.

ShareHouse Inc

ShareHouse Inc, located in Fargo, ND, provides an all-encompassing approach to substance abuse recovery, paired with transitional housing solutions including sober living facilities and halfway houses. Their services are designed for adults facing both substance use challenges and significant mental health concerns, as well as children dealing with emotional issues. With various options available, including long-term and short-term residential stays, the center utilizes proven methods such as 12-step programs, anger management techniques, and cognitive behavioral therapy. ShareHouse Inc is dedicated to offering tailored support for adult men, women, and individuals who have gone through trauma, ensuring high-quality, personalized care for all adults and young adults, regardless of gender.

Shawnee Healthcare
Murphysboro, IL

Shawnee Healthcare, situated in Murphysboro, Illinois, provides dedicated outpatient treatment for individuals of all ages facing challenges with substance use, co-occurring mental health conditions, and emotional difficulties. Their approach incorporates scientifically-backed methods such as anger management, brief intervention techniques, and cognitive behavioral therapy. Shawnee Healthcare features distinct programs designed for adult men and women, fostering a secure setting conducive to healing and recovery. This center also extends its outpatient services, including methadone, buprenorphine, or naltrexone treatment options, to adults and young adults of all gender identities, complementing their general outpatient care. At Shawnee Healthcare, clients can anticipate high-quality support and individually crafted treatment strategies aimed at facilitating addiction recovery and enhancing emotional health.

Seven Hills Behavioral Health

Seven Hills Behavioral Health in Milford, MA, provides outpatient care for adults dealing with substance use and/or co-occurring mental health concerns, as well as for children experiencing emotional disturbances. Their therapeutic modalities include anger management techniques, brief intervention strategies, and cognitive behavioral therapy. The center features tailored programs for adolescents, survivors of intimate partner violence, domestic violence, and individuals who have endured sexual abuse. Their services are designed for adults and children/adolescents across all gender identities. With a holistic approach and a strong emphasis on personalized treatment plans, Seven Hills Behavioral Health stands out as a leading option for effective rehabilitation services within the Milford community.

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Seven Counties Services in Shelbyville, KY, provides comprehensive care for individuals struggling with addiction and co-occurring mental health conditions, serving both adults and children. The facility offers a range of residential options, including long-term, short-term, and 24-hour programs, all designed to deliver personalized support. Treatment methodologies employed include 12-step facilitation, brief intervention, and cognitive behavioral therapy. The center also features distinct programs developed specifically for women, alongside general services accessible to adults, seniors, and young adults. This specialized approach ensures dedicated and effective treatment for all seeking recovery from substance use disorders.

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Seven Counties Services, located in Shelbyville, KY, provides outpatient treatment for substance use disorders in both adults and children who also face mental health issues. Utilizing evidence-supported methods such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, this center is dedicated to personalized care. It features distinct programs for adult men and women, as well as young adults, fostering a nurturing atmosphere conducive to recovery. Their gender-specific offerings allow for customized treatment plans that address each client's unique circumstances, establishing Seven Counties Services as an essential option for individuals in need of thorough and impactful rehabilitation support.

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Seven Counties Services, located in Louisville, KY, provides an extensive range of services for individuals dealing with substance use disorders, as well as those facing concurrent mental health challenges in adults and emotional difficulties in children. The center offers both residential and short-term residential treatment options, employing methodologies such as 12-step facilitation, brief interventions, and cognitive behavioral therapy. There is also a dedicated program designed specifically for adult women. Catering to a diverse demographic including adults, seniors, and young adults, the facility emphasizes care that is responsive to the needs of women. With its commitment to high-quality treatment and customized programs, the center stands out as an optimal choice for individuals in search of effective rehabilitation in a nurturing atmosphere.

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Seven Counties Services, located in La Grange, KY, provides outpatient treatment for adults dealing with substance use issues alongside serious mental health conditions, as well as emotional difficulties in children. The center employs a range of therapeutic methods, including 12-step facilitation, brief interventions, and cognitive behavioral therapy. Focused on serving both adult men and women, this facility offers specialized programs designed to meet the unique requirements of each client. With an emphasis on evidence-based practices and individualized treatment strategies, Seven Counties Services is committed to assisting individuals as they navigate their path to recovery from substance abuse and mental health issues.

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Warren, MI

Located in Warren, MI, SHAR Macomb provides an extensive variety of substance use treatment options. This center is dedicated to addressing co-occurring substance use disorders along with significant mental health issues in adults and serious emotional challenges in children. Emphasizing long-term residential, 24-hour residential, and short-term residential offerings, SHAR Macomb delivers personalized care utilizing methods such as 12-step facilitation, anger management, and brief intervention strategies. Specialized programs are available for adult men, adult women, and individuals who have faced trauma. Catering to adults and young adults of all genders, this facility emphasizes high-quality care and customized treatment plans aimed at fostering enduring recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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