Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.
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Southern Arizona VA Healthcare Servs, located in Tucson, AZ, provides a wide range of addiction recovery services specifically designed for adults and young adults experiencing substance use disorders alongside mental health challenges. The center features inpatient detoxification and treatment programs, with specialized care available for those who have faced trauma, domestic violence, sexual abuse, or intimate partner violence. By employing evidence-based methods such as 12-step programs, anger management strategies, and brief therapeutic interventions, this facility focuses on delivering customized treatment for both genders. Committed to quality care and personalizing the recovery process, this center aims to guide clients toward a healthier future.

Southeast Missouri Behavioral Health, situated in Poplar Bluff, MO, delivers thorough care for both addiction and intertwined mental health conditions affecting individuals of all ages. Their approach centers on tailored treatment, featuring intensive outpatient, standard outpatient, and day treatment options. Employing methodologies like 12-step support, emotional regulation skills, and cognitive restructuring, the facility welcomes male and female patients. The dedication to high standards and bespoke recovery paths distinguishes this center as a reliable choice for individuals pursuing successful rehabilitation.

At Southeastern Arizona Behavioral Health in Safford, AZ, we provide outpatient care for individuals and young people struggling with substance misuse, especially when it occurs alongside mental health challenges. Our standard outpatient services incorporate techniques like anger management, brief intervention strategies, and cognitive behavioral therapy. This center is particularly adept at assisting those who are dealing with both mental health and addiction issues simultaneously. We cater to adults and older adults of all backgrounds, guaranteeing excellent care and personalized recovery strategies. Southeastern Arizona Behavioral Health is recognized for its thorough methods in addressing addiction and co-occurring conditions, establishing itself as a vital provider of effective and caring recovery solutions.

Southern Family Medicine in Mooresville, NC, is a dedicated facility offering extensive outpatient rehabilitation for those facing substance use challenges and co-occurring mental health concerns. The center provides targeted care for adults with severe mental health conditions, children with significant emotional difficulties, active military members, adult men, and survivors of intimate partner violence. Their therapeutic modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Committed to personalized, high-quality treatment, Southern Family Medicine serves clients of all ages and genders, delivering outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone alongside standard outpatient care.

Southern CA Alcohol and Drug Prog Inc, located in Bellflower, CA, delivers extensive addiction recovery services tailored for women, seniors, and young adults. The center is dedicated to detox programs, treatment for substance use disorders, and addressing dual diagnoses for those facing both substance abuse and significant mental health challenges. They offer a range of options including long-term residential care, residential detox, and round-the-clock residential services. Emphasizing techniques like 12-step support, anger management, and focused intervention strategies, the facility customizes treatment plans to fit the unique requirements of each individual. Additionally, the center features specialized programs for adult women and those who have experienced intimate partner violence, domestic abuse, or sexual trauma, fostering a nurturing environment conducive to recovery. At Southern CA Alcohol and Drug Prog Inc, clients are met with compassionate support and proven treatment methodologies.

Situated in Downey, CA, Southern CA Alcohol and Drug Prog Inc provides dedicated long-term residential services for women facing substance use challenges alongside significant mental health disorders. The center creates customized treatment plans that include 12-step support, anger management techniques, and brief therapeutic interventions. Emphasizing care for adult women who have undergone experiences of intimate partner violence, domestic abuse, or sexual trauma, this facility fosters a nurturing atmosphere conducive to recovery. Catering to adults, seniors, and young adults, this residential program ensures thorough care and personalized support aimed at achieving sustainable sobriety and enhancing emotional health.

Southern CA Alcohol and Drug Prog Inc, located in Downey, CA, provides extensive residential care focused on helping adults overcome addiction and mental health challenges. Their specialized services include detox, comprehensive substance use disorder treatment, and support for adults with serious mental health conditions and children experiencing emotional disturbances. This facility delivers round-the-clock support through evidence-based methods such as 12-step integration, anger management training, and brief intervention strategies. Distinctive programs are available for adult men, including those with a background of domestic violence or past sexual trauma. The center primarily serves adult and senior men, dedicated to offering superior care and encouragement for individuals pursuing sobriety and mental well-being.

Southern Family Medicine, situated in Mocksville, NC, provides extensive outpatient rehabilitation. Their expertise lies in treating substance use disorders and dual diagnoses for individuals of all ages. They employ techniques such as anger management, cognitive behavioral therapy, and brief intervention to create personalized treatment plans. Distinctive offerings include specialized programs for military personnel, adult males, and survivors of domestic abuse. Catering to both adults and children, Southern Family Medicine delivers high-quality care to all. They offer outpatient services, including methadone/buprenorphine treatment, to support those pursuing recovery.

Southeast Missouri Behavioral Health, situated in Piedmont, MO, provides expert care for individuals of all ages facing substance use challenges and co-occurring mental health conditions. Their comprehensive offerings include intensive outpatient and standard outpatient programs, featuring medication-assisted treatment with methadone or buprenorphine. They employ proven therapeutic strategies such as 12-step facilitation and cognitive behavioral therapy. This center is dedicated to personalized treatment plans for both male and female patients, fostering a nurturing atmosphere conducive to healing. Their services extend to specialized needs like anger management, reflecting a steadfast dedication to delivering high-quality, complete care.

Southeast Missouri Behavioral Health, situated in Farmington, MO, delivers a full spectrum of substance abuse recovery options. Their offerings include inpatient detox, round-the-clock residential support, and brief residential stays designed for adults and young people. The center's expertise lies in guiding clients through the 12-step process, employing cognitive behavioral strategies, and teaching effective anger management. Emphasizing a personalized approach, they craft treatment paths specific to each individual's circumstances. For those needing detox, addiction treatment, or temporary lodging, Southeast Missouri Behavioral Health provides excellent care within a nurturing setting. Dedicated tracks are provided for male and female patients.

At Southeastern Integrated Care LLC in Pembroke, NC, adults and youth facing substance use challenges alongside serious mental health concerns receive specialized outpatient care. The center features distinct programs catering to adolescents, adult men, and adult women. Treatment options encompass outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone), anger management techniques, and brief intervention strategies. They also offer individualized 12-step facilitation. Serving a diverse population including adults and seniors of all genders, Southeastern Integrated Care LLC is committed to utilizing proven therapeutic approaches and crafting unique recovery journeys. Their focus is on delivering thorough and empathetic rehabilitation services to individuals seeking support.

Southeast Missouri Behavioral Health, situated in Cadet, MO, delivers extensive care for substance use issues and co-occurring mental health conditions, serving both young people and adults. They offer robust programs including intensive outpatient, standard outpatient, and day treatment, employing proven methods like 12-step guidance, emotional regulation skills, and cognitive behavioral interventions. This center prioritizes personalized treatment, welcoming both male and female patients and crafting unique recovery strategies for everyone. Southeast Missouri Behavioral Health distinguishes itself through its dedication to high-quality, specialized treatment designed to meet the specific challenges of each individual, establishing it as a premier option for those pursuing effective and customized recovery support.

Southeast Missouri Behavioral Health, situated in Farmington, MO, delivers extensive support for substance use disorders and targeted assistance for those facing co-occurring severe mental health conditions or emotional distress. Emphasizing personalized care, their offerings encompass intensive outpatient, standard outpatient, and day treatment modalities. The center's therapeutic interventions include 12-step facilitation, anger management techniques, and cognitive behavioral therapy, catering to both adults and young people. Designed to address the distinct requirements of each individual, this institution provides distinct programs for men and women. Southeast Missouri Behavioral Health is committed to delivering exceptional services to aid individuals in their journey toward lasting recovery.

Southeastern Arizona Behavioral Health in Douglas, AZ, provides extensive outpatient services for individuals grappling with addiction and overlapping mental health conditions. The center is particularly adept at treating significant emotional disruptions in both children and adults who have a dual diagnosis. Their therapeutic framework employs proven techniques including cognitive behavioral therapy, strategies for managing anger, and concise intervention methods, all designed to offer personalized care. Emphasizing clients with co-occurring conditions, the center serves adults and older adults, irrespective of gender. Southeastern Arizona Behavioral Health is committed to offering superior treatment and assistance to those pursuing effective recovery for substance dependency and psychological health challenges.

In Sierra Vista, AZ, Southeastern Arizona Behavioral Health delivers thorough care for addiction and dual diagnosis in both young people and adults. The facility offers various levels of care, including intensive outpatient, outpatient, and standard outpatient services, employing methods like anger management, brief intervention, and cognitive behavioral therapy. Focusing on individuals with both mental health and substance abuse challenges, this establishment serves adults and older adults of any gender. Dedicated to high-quality treatment and proven therapeutic techniques, Southeastern Arizona Behavioral Health strives to support individuals in attaining sustained recovery and improved emotional health.

Southeastern Arizona Behavioral Health in Benson, AZ provides a variety of distinct treatment options designed for each individual. This center delivers intensive outpatient care, standard outpatient services, and ongoing outpatient treatment for those struggling with addiction, co-occurring psychological issues, and emotional distress. Utilizing therapeutic modalities such as anger management, brief interventions, and cognitive behavioral therapy, patients are provided with thorough support. The facility is equipped to serve adults and older adults, with distinct programs for men and women. Southeastern Arizona Behavioral Health is committed to delivering excellent, personalized support to facilitate sustained recovery and enhanced mental health.

Southern Addiction Medicine Services, situated in Covington, LA, delivers comprehensive outpatient care for addiction. Their services encompass detoxification, substance use disorder treatment, and medication-assisted treatment including methadone, buprenorphine, or naltrexone. They offer distinct programs for adult men and women, serving both younger and older adults. Therapeutic methods employed consist of 12-step facilitation, brief intervention, and cognitive behavioral therapy. Dedicated to superior patient outcomes, the center provides personalized care for individuals of all genders pursuing freedom from addiction. Southern Addiction Medicine Services distinguishes itself with its all-encompassing outpatient offerings and customized treatment strategies aimed at fostering enduring recovery and overall well-being.

Situated in Oakland, CA, the Southern Alameda County Comite offers premium substance use rehabilitation services tailored for adult males. This center provides both long-term and around-the-clock residential treatment options, emphasizing 12-step methodology, anger control strategies, and short intervention techniques. It is dedicated to assisting active duty service members, adult males, and individuals impacted by domestic or intimate partner violence. With customized programs designed for adults, seniors, and younger adults, the facility is committed to delivering exceptional care and support for men pursuing recovery from substance use issues.

Southern Highlands CMHC Inc, located in Princeton, WV, provides in-depth treatment for substance use issues targeting adult men, seniors, young adults, and other adults. The center focuses on addressing both co-occurring substance use disorders and significant mental health conditions. It offers various treatment options, including long-term, short-term, and round-the-clock residential programs, all designed to ensure personalized care. The therapeutic strategies employed include anger management, brief interventions, and cognitive behavioral therapy. Tailored programs are available specifically for adult men and those facing both mental health and substance use challenges. Committed to delivering exceptional care with specialized approaches for different groups, this facility is focused on empowering individuals to achieve enduring recovery.

Southern Highlands CMHC Inc, situated in Princeton, WV, provides thorough outpatient care for those requiring detoxification and help with substance use. They are experts in addressing co-occurring substance use disorders alongside significant mental health conditions in adults and severe emotional disturbances in young people. Their therapeutic methods encompass anger management, brief intervention, and cognitive behavioral therapy. Furthermore, they offer tailored programs for teenagers, serving adults and children/adolescents alike. Southern Highlands CMHC Inc prioritizes high-quality service, creating personalized treatment strategies for male and female patients within a nurturing and healing setting.

Southern Highlands CMHC Inc, located in Welch, WV, provides outpatient substance abuse recovery services for adults, including individuals facing concurrent mental health challenges. Their expertise lies in areas such as anger management techniques, cognitive behavioral therapy, and short-term counseling approaches. The facility is equipped to deliver personalized support to adults and younger individuals alike. For those requiring it, Southern Highlands CMHC Inc also offers outpatient pharmacotherapy for opioid use disorder, utilizing medications like methadone, buprenorphine, or naltrexone. Their commitment to a personalized, gender-inclusive approach ensures that every client receives specialized and effective treatment designed for their distinct circumstances.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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