Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.
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Spero Health, located in Pikeville, KY, provides outpatient services for those struggling with substance use, specializing in treatments involving methadone, buprenorphine, and naltrexone. The center offers regular outpatient programs as well as tailored initiatives for adult men and women, including support for individuals who have faced intimate partner or domestic violence. Serving both adults and young adults of all genders, Spero Health employs a holistic strategy for recovery that encompasses anger management, brief interventions, and cognitive behavioral therapy. With a dedication to high-quality care and personalized treatment strategies, Spero Health stands out as a reliable option for individuals seeking meaningful and empathetic support in their journey to overcome addiction.

Situated in Penn Run, PA, SpiritLife Inc delivers extensive addiction recovery services for both adult males and females. The center features long-term residential treatment, residential detox services, and round-the-clock support. Focusing on 12-step methods, anger management, and short intervention strategies, SpiritLife Inc addresses the needs of clients affected by intimate partner and domestic violence. With programs designed for adults and young adults of all genders, the facility prioritizes personalized care and support for each individual's path to healing. Rely on SpiritLife Inc for exceptional, tailored rehabilitation services in a nurturing and encouraging atmosphere.

Spokane Falls Recovery Center, situated in Spokane, WA, specializes in extended residential care for addiction and chemical dependency. Their treatment strategies encompass a variety of methods, such as 12-step integration and techniques for managing anger. They cater to adults and young adults across all gender identities, offering personalized support. The center's dedication to a unique treatment path for each individual is a key feature, guaranteeing that care plans are specifically designed for every client's particular circumstances. For those requiring inpatient detox or round-the-clock supervision, Spokane Falls Recovery Center delivers effective, research-supported therapy.

Spinal Interventions in Provo, UT, provides specialized outpatient services for adults and young individuals struggling with substance use disorders. Their approach emphasizes customized treatment plans, incorporating methods such as brief interventions, cognitive behavioral therapy, and motivational interviewing. The center is committed to delivering high-quality, effective care, including outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone. Spinal Interventions serves all genders and aims to offer a holistic path to recovery. For those looking for a tailored, evidence-driven recovery program, Spinal Interventions is prepared to assist you in achieving a life free from addiction.

Situated in Madison, TN, Spero Health stands out as a prominent outpatient rehabilitation facility that focuses on treating substance use disorders. The center provides outpatient options such as methadone, buprenorphine, or naltrexone therapies, alongside conventional outpatient services and a range of therapeutic modalities, including anger management, brief interventions, and cognitive behavioral therapy. Spero Health serves adults of all genders, particularly those who have faced intimate partner violence or domestic abuse. By emphasizing personalized care for men and women, this center becomes an essential support system for individuals pursuing successful addiction recovery initiatives.

Spero Health, located in Canton, OH, specializes in outpatient treatment for individuals grappling with substance use, including both adults and young adults. The center employs a range of methodologies, such as anger management, brief intervention sessions, and cognitive behavioral therapy. They offer tailored programs designed for adult men, adult women, and those who have faced intimate partner or domestic violence. Emphasizing personalized care, Spero Health ensures an inclusive and supportive atmosphere for all clients. If you are looking for effective outpatient treatment options like methadone, buprenorphine, or naltrexone, this facility is committed to aiding individuals as they pursue recovery.

SperoHealth, located in Columbus, OH, provides a wide range of substance use treatment options, including intensive outpatient programs, outpatient services, and medication-assisted treatments such as methadone, buprenorphine, or naltrexone. The facility is known for its specialized programs in anger management, brief intervention, and cognitive behavioral therapy. Tailored initiatives are available for adult men and women, as well as individuals who have faced intimate partner violence. SperoHealth serves both adults and young adults from all backgrounds, ensuring a nurturing atmosphere for those on the path to recovery. Emphasizing high-quality care and research-backed methods, the center develops individualized treatment plans that cater to the varied requirements of each client, promoting effective rehabilitation and overall health.

Spero Health, located in Savannah, TN, specializes in outpatient treatment for substance use, emphasizing personalized care and high-quality support. The center offers a variety of services including outpatient treatments with methadone, buprenorphine, or naltrexone, alongside traditional outpatient programs. Additionally, Spero Health incorporates multiple therapeutic methods such as anger management, brief interventions, and cognitive behavioral therapy. This facility serves adult men and women, including those who have faced domestic or intimate partner violence. By focusing on tailored care, Spero Health aims to assist both adults and young adults in their recovery journey.

Spero Health in Clarksville, TN, delivers personalized outpatient recovery support for adults and emerging adults. They have distinct programs for adult men and women, as well as those affected by intimate partner or domestic violence. Employing methods such as anger management, brief intervention, and cognitive behavioral therapy, this location emphasizes custom treatment plans. Spero Health provides medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient services. Catering to both male and female individuals, the center is dedicated to providing excellent, all-encompassing support for lasting recovery.

Spero Health in Smyrna, TN, delivers comprehensive outpatient recovery services for adults and young adults. Their treatment options include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. The facility also offers specialized programs focusing on anger management, brief intervention strategies, and cognitive behavioral therapy. Spero Health is uniquely equipped to support adult men, adult women, and individuals impacted by intimate partner or domestic violence. They are dedicated to providing personalized treatment and employing proven, effective methods for all clients, irrespective of gender. For those looking for a supportive setting and thorough addiction care, Spero Health provides expert services and tailored programs.

Spero Health, situated in Hopkinsville, KY, focuses on outpatient treatment for substance use disorders affecting both adults and young adults. The center delivers targeted support using methods such as anger management, brief interventions, and cognitive behavioral therapy. Catering to specific groups including adult men, adult women, and individuals who have faced intimate partner or domestic violence, Spero Health is committed to providing personalized care. They offer various outpatient treatment options including methadone, buprenorphine, and naltrexone to meet unique patient needs. With a dedication to quality care for all clients, this center stands out as a trustworthy option for those in need of effective and empathetic addiction recovery services.

Spero Health, located in Lancaster, OH, provides comprehensive outpatient services, including intensive outpatient programs and treatment options utilizing methadone, buprenorphine, or naltrexone for those dealing with substance use challenges. Their methodology encompasses therapies such as anger management, cognitive behavioral therapy, and brief intervention strategies. The center features specialized programs catering to adult men and women, as well as those affected by intimate partner or domestic violence. Spero Health serves a diverse clientele of adults and young adults, ensuring that care is personalized to meet the unique requirements of each individual. Committed to evidence-based methods and holistic support, Spero Health strives to help individuals navigate their recovery journey effectively.

Spokane Addiction Recovery Centers, situated in Spokane, WA, focuses on delivering tailored substance use treatment for adult males. This center is equipped to handle the complexities of individuals who are also facing mental health challenges. It offers both residential and short-term residential treatment options, employing proven methods including 12-step programs, cognitive behavioral therapy, and motivational interviewing. Catering specifically to adult, senior, and young adult men, the facility prioritizes personalized care that addresses the specific requirements of each individual. Spokane Addiction Recovery Centers is committed to high-quality addiction recovery support in a nurturing therapeutic setting.

Situated in Spokane, WA, Spokane Addiction Recovery Centers specializes in providing targeted substance use treatment specifically for adult women. This facility offers a holistic approach to care, particularly for those struggling with both substance use and significant mental health challenges. With options for residential and short-term residential treatment, the center employs proven methodologies such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. Their distinct programs are designed to meet the needs of adult women as well as clients dealing with co-occurring disorders. Catering to adults of all ages, including seniors and young adults, this center is dedicated to offering personalized, high-quality care that addresses the unique requirements of each individual. For women in pursuit of effective and empathetic addiction recovery solutions, Spokane Addiction Recovery Centers is a reliable option.

Spokane Addiction Recovery Centers, situated in Spokane, WA, offers dedicated therapeutic services for individuals grappling with addiction and concurrent mental health conditions. This establishment features both long-term and brief residential care options, specifically designed to meet the needs of adult men facing co-occurring disorders. Their approach incorporates proven methodologies such as 12-step support, cognitive behavioral therapy, and motivational interviewing to provide complete assistance for those pursuing sobriety. Serving adults, older individuals, and younger adults, this program is structured to address the distinct requirements of its male clientele. Spokane Addiction Recovery Centers is committed to delivering exceptional care through scientifically validated methods, positioning it as a premier resource for individuals confronting addiction and psychological health concerns.

Situated in Spokane, WA, Spokane Addiction Recovery Centers delivers extensive substance abuse treatment specifically designed for adult women in a nurturing and secure atmosphere. This center focuses on providing tailored support for individuals facing co-occurring mental health issues using proven methods such as cognitive behavioral therapy and motivational interviewing. Offering both residential and short-term residential options, the facility serves adults, seniors, and young adults who are in pursuit of effective treatment. With distinctive programs aimed at women and those dealing with integrated disorders, Spokane Addiction Recovery Centers stands out as an excellent option for individuals aiming to conquer addiction and enhance their mental well-being.

Spero Health, located in Seymour, TN, offers extensive outpatient treatment programs for individuals dealing with substance use issues, including both adults and young adults. The center provides various outpatient options, such as methadone, buprenorphine, and naltrexone therapies, alongside standard outpatient services. It emphasizes specific areas like anger management, brief intervention, and cognitive behavioral therapy. Spero Health supports adult men and women, including those who have faced intimate partner or domestic violence. By prioritizing personalized care, the center guarantees high-quality treatment for patients in a nurturing environment, promoting effective recovery solutions.

Spero Health, situated in Danville, VA, provides outpatient care for substance use disorders aimed at adult men, women, and younger adults. The center features tailored programs for individuals affected by intimate partner or domestic violence. Treatment modalities encompass anger management, brief interventions, and cognitive behavioral therapy. Additionally, Spero Health administers outpatient services for methadone, buprenorphine, or naltrexone, alongside standard outpatient treatment. Committed to delivering high-quality care and personalized treatment strategies, this center strives to support individuals in overcoming addiction and attaining sustained recovery.

Spokane Treatment and Recovery Service, situated in Spokane, WA, provides extensive long-term residential care for adult women battling substance use disorders. The center focuses on dual diagnoses of substance use and significant emotional challenges in children. Employing proven therapeutic methods like 12-step facilitation, anger management, and cognitive behavioral therapy, they deliver personalized support to individuals impacted by intimate partner violence, domestic abuse, and sexual trauma. Serving adults, older adults, and young adults, this center is committed to offering excellent care and encouragement to women on their journey toward recovery and well-being.

In Orange, TX, Spindletop Center provides a full spectrum of recovery support for individuals, both young and old, facing challenges with substance abuse and coexisting mental health conditions. Their program offerings include intensive outpatient, standard outpatient, and less intensive outpatient treatment tracks. Therapeutic methods employed encompass 12-step facilitation, anger management techniques, and brief intervention strategies. Targeted services are available for teenagers, adult women, and individuals managing both mental health and addiction concerns. Committed to high-quality, personalized care, Spindletop Center strives to empower clients on their journey to sustained well-being. The center welcomes both male and female participants, fostering a welcoming and understanding atmosphere for anyone aiming to conquer addiction.

Situated in Orange, TX, Spindletop Center presents a wide array of treatment options for adults and young adults dealing with substance use issues. This center is particularly adept at addressing co-occurring substance use disorders alongside significant mental health challenges in adults, as well as addressing serious emotional disturbances in youth. Offering various treatment modalities, including intensive outpatient, outpatient, and standard outpatient programs, the facility tailors its care to individual needs through evidence-based methods such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing. Unique programs are available for active duty military members, as well as separate services for adult men and women. With a strong emphasis on high-quality care, Spindletop Center is dedicated to providing effective rehabilitation for both male and female clients.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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