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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Synergy Executive

Situated in Ozark, MO, Synergy Executive stands out as a leading rehabilitation facility dedicated to providing extensive addiction recovery services. The center focuses on long-term residential treatment, encompassing detox and continuous support around the clock. Emphasizing a 12-step approach, anger management, and cognitive behavioral therapy, the program is designed for adult men facing challenges related to substance abuse and concurrent mental health issues. Synergy Executive also features tailored programs for clients who have undergone trauma, ensuring personalized attention. Catering to adults of all ages, this center creates a secure and nurturing atmosphere for male individuals pursuing effective rehabilitation solutions.

Synergy Recovery Center

Synergy Recovery Center, located in Rogersville, MO, offers a wide array of targeted services for those grappling with addiction. This facility features residential detox options and various residential programs designed to help adults facing substance use disorders as well as co-occurring mental health issues. By employing methods such as 12-step support, anger management techniques, and cognitive behavioral therapy, the center customizes treatment strategies to meet the unique needs of each individual. Additionally, Synergy Recovery Center has specialized programs tailored for women, including active military personnel, adult women, and those who have faced intimate partner violence. Committed to delivering high-quality care, the center serves adults, seniors, and young adults who are in search of comprehensive and individualized support for their recovery journey.

Syracuse Community Health Center

Syracuse Community Health Center located in Syracuse, NY, offers focused treatment for adults who are dealing with substance use issues alongside significant mental health disorders, as well as support for children experiencing serious emotional challenges. The center provides both intensive outpatient and standard outpatient programs, with options for methadone and buprenorphine therapies. Emphasizing 12-step processes, anger management techniques, and short interventions, the facility adopts a personalized care strategy for individuals across all age groups and genders. Syracuse Community Health Center is recognized for its holistic approach and dedication to meeting the distinct needs of each patient within a nurturing setting.

Syracuse VAMC
Syracuse, NY

Syracuse VAMC, situated in Syracuse, NY, delivers extensive rehabilitation programs. Their expertise lies in helping individuals overcome addiction, providing treatment for substance use issues, and addressing dual diagnoses involving serious mental health conditions in adults or emotional challenges in children. The facility provides intensive outpatient care, standard outpatient services, and outpatient detoxification. Focusing on techniques like anger management, brief intervention, and cognitive behavioral therapy, the center welcomes active-duty military personnel, adult men, and adult women. Syracuse VAMC is committed to offering excellent care in a nurturing setting to adults and young adults, irrespective of gender.

Symetria Recovery
Warrenville, IL

Symetria Recovery, located in Warrenville, IL, provides thorough addiction care for adults and young adults. This center delivers detox services, addiction treatment, and specialized support for those with dual diagnoses involving substance use and mental health conditions. Offering flexible options such as intensive outpatient, outpatient detox, and general outpatient therapy, Symetria Recovery ensures accessible support at multiple care levels. Their treatment philosophy incorporates techniques like anger management, brief intervention, and cognitive behavioral therapy, customized to each person's unique needs. Symetria Recovery is committed to personalized care, ensuring every client receives tailored attention. Welcoming all genders, the center fosters a secure and encouraging atmosphere.

Symetria Recovery
Des Plaines, IL

Symetria Recovery in Des Plaines, IL, provides extensive addiction treatment for adults and adolescents. They focus on detox, general substance use disorder care, and treating co-occurring mental health conditions in adults or emotional challenges in youth. Their personalized approach features intensive outpatient care, standard outpatient programs, and outpatient detox. Employing methods like anger management, brief intervention, and cognitive behavioral therapy, Symetria Recovery offers custom support to men and women pursuing sobriety. Their dedication to high-standard care establishes them as a key provider of effective, individualized recovery solutions.

Symetria Recovery

Symetria Recovery in Houston, TX, delivers thorough substance abuse treatment for individuals and adolescents struggling with addiction and coinciding mental health issues. They offer intensive outpatient care, standard outpatient programs, and outpatient detox options. Emphasizing personalized care plans, Symetria Recovery employs proven methods such as cognitive behavioral therapy, anger management techniques, and brief intervention strategies. This facility welcomes both male and female patients, fostering a nurturing and equitable atmosphere for everyone. For those in search of tailored and successful addiction treatment, Symetria Recovery is committed to delivering excellent support to guide patients toward lasting sobriety.

Synergy Counseling Center

Synergy Counseling Center, located in Springfield, MO, specializes in the treatment of substance abuse and simultaneous mental health issues for both adults and children. It provides a range of services including intensive outpatient, outpatient, and day treatment programs, emphasizing 12-step methods, anger management, and short-term intervention strategies. The center is particularly noted for its specialized programs designed for individuals who have faced trauma and those dealing with dual diagnoses. Catering to clients of all ages and genders, Synergy Counseling Center focuses on personalized care and guidance, fostering healing and recovery within a nurturing and professional setting.

Symetria Recovery
College Station, TX

Symetria Recovery, located in College Station, TX, delivers a full spectrum of addiction treatment solutions. Their offerings include detox, substance abuse care, and specific interventions for dual diagnoses, encompassing mental health disorders in adults or emotional challenges in adolescents. Through intensive outpatient, standard outpatient, and outpatient detox programs, Symetria Recovery customizes treatment plans. The center employs scientifically validated methods such as CBT, anger management techniques, and short-term counseling. A defining characteristic of their approach is the emphasis on personalized treatment, guaranteeing each patient receives dedicated support. Symetria Recovery in College Station provides exemplary care in a nurturing setting for adults and young adults, irrespective of gender.

TLC Treatment Center

TLC Treatment Center, situated in Mesa, Arizona, provides an extensive range of services for individuals dealing with substance use issues, including options for transitional housing and sober living. The center features intensive outpatient care alongside outpatient and partial hospitalization programs. Emphasizing 12-step support, anger management, and brief therapeutic interventions, it serves both adult men and women, as well as those who have faced sexual abuse. TLC Treatment Center focuses on adults and young adults, offering gender-specific programming tailored for both sexes. With a strong dedication to delivering high-quality care and personalized treatment plans, this center is committed to assisting clients throughout their recovery process.

Syracuse Recovery Services

Syracuse Recovery Services in Cortland, NY, delivers customized outpatient substance use disorder services. The facility specializes in supporting adult men, adult women, and individuals with trauma histories. Their therapeutic methods encompass brief interventions, cognitive behavioral therapy, and contingency management/motivational incentives. Catering to a broad demographic, they offer programs for adults and young people. The center provides outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care, prioritizing effective and individualized recovery journeys.

TCN Behavioral Health Services Inc

TCN Behavioral Health Services Inc, located in Fairborn, OH, provides extensive support for individuals battling substance use disorders, along with targeted interventions for those managing co-occurring severe mental health challenges. Their diverse treatment offerings are designed for both young people and adults, encompassing intensive outpatient, day treatment, and partial hospitalization programs. Emphasizing methodologies such as 12-step support, anger resolution, and short-term counseling, the center delivers personalized care plans. Dedicated services are provided for teenagers, adult men, and adult women. TCN Behavioral Health Services Inc serves a broad spectrum of clients, including males and females of all ages, from adults to seniors, who are pursuing a path to recovery and improved mental well-being.

Symetria Recovery
Fort Worth, TX

Symetria Recovery in Fort Worth, TX, provides targeted interventions for substance abuse, withdrawal management, and dual diagnoses impacting adults with significant mental health challenges or minors experiencing emotional difficulties. Their structured day treatment and less intensive programs utilize proven methodologies such as emotional regulation skills, motivational interviewing, and dialectical behavior therapy. Emphasizing personalized support, this center serves adults and adolescents across the gender spectrum. Symetria Recovery is recognized for its extensive offerings and dedication to high-standard care, presenting a strong option for individuals pursuing robust recovery solutions within the Fort Worth region.

Syracuse Recovery Services

Syracuse Recovery Services located in Auburn, NY, specializes in outpatient care for substance use disorders, emphasizing personalized treatment plans. The facility offers services such as outpatient methadone/buprenorphine and naltrexone therapies, along with standard outpatient programs. By employing proven methodologies including cognitive behavioral therapy and contingency management, the center serves adults of all genders and ages, including those who have faced traumatic experiences. Catering to both adults and youth, the center adopts a holistic approach to recovery. Syracuse Recovery Services in Auburn, NY, is committed to delivering effective addiction treatment that recognizes and responds to the distinct needs of every individual.

TCN Behavioral Health Services Inc

TCN Behavioral Health Services Inc, located in Xenia, OH, delivers an extensive array of rehabilitation services with a focus on substance abuse treatment, transitional living arrangements, and support for individuals dealing with both substance use disorders and severe mental health issues. This center provides various program options, including long-term, short-term, and round-the-clock residential care, employing customized strategies such as 12-step programs, anger management sessions, and brief intervention tactics. TCN Behavioral Health Services Inc also offers specialized programs designed for adolescents, adult males, and individuals who have faced intimate partner violence, addressing the specific needs of men and older adults. Clients can expect high-quality care and assistance in a secure and organized setting at this rehabilitation center.

TCN Behavioral Health Services Inc

TCN Behavioral Health Services Inc in Xenia, OH, provides an extensive array of rehabilitation treatments. This center specializes in detoxification, addressing substance use disorders, and offering tailored support for those with both substance use problems and severe mental health conditions. Treatment options include intensive outpatient care, standard outpatient services, and partial hospitalization. The facility employs research-backed methods such as 12-step programs, anger management, and brief therapeutic interventions. TCN Behavioral Health Services also offers dedicated programs for teens, as well as adult men and women, ensuring a wide breadth of support. Aiming to assist adults and seniors of all genders, this center is committed to offering exceptional care to help individuals progress on their recovery journey.

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Syracuse Recovery Services LLC, based in Syracuse, NY, provides a wide range of treatment options for individuals struggling with substance use issues, targeting both adults and teens. The facility specializes in outpatient care that includes medications like methadone, buprenorphine, or naltrexone, as well as cognitive behavioral therapy and brief intervention strategies. Additionally, there are specific programs designed for adult men, adult women, and individuals who have faced trauma. Committed to delivering high-quality support, the center caters to both males and females on their path to recovery. Syracuse Recovery Services LLC is distinguished by its personalized treatment plans, ensuring that every client receives the specific assistance they need to achieve lasting sobriety.

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Situated in Tok, AK, TCC Upper Tanana Behavioral Health is dedicated to addressing substance use challenges for adults dealing with concurrent mental health conditions and for children facing significant emotional difficulties. The center offers both intensive outpatient and outpatient treatment options, including the use of methadone, buprenorphine, or naltrexone as part of its program. Utilizing methods such as 12-step support, anger management techniques, and short-term interventions, the facility serves clients of all genders. TCC Upper Tanana Behavioral Health is particularly recognized for its commitment to those with dual diagnoses, providing thorough assistance for individuals of all ages as they navigate their path to recovery.

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TCN Behavioral Health Services Inc, located in Dayton, OH, provides a wide range of services aimed at treating addiction. The center offers detox services, treatment for substance use disorders, and targeted programs for adults facing both substance use and severe mental health challenges. Their treatment options include intensive outpatient care, outpatient services, and day treatment. Employing evidence-based methods, TCN incorporates strategies such as 12-step facilitation, anger management, and short interventions in their programs. Additionally, there are specialized services for adolescents, as well as tailored programs for adult men and women. TCN Behavioral Health Services is committed to delivering exceptional care to adults and seniors, ensuring effective support for all individuals on their recovery journey.

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TCN Behavioral Health Services Inc. in Bellefontaine, OH, delivers extensive care for adults struggling with substance misuse, particularly those with co-occurring serious mental health conditions or children experiencing emotional distress. The facility offers a range of therapeutic services, including intensive outpatient programs, standard outpatient services, and day treatment. TCN addresses the needs of specific demographics with tailored programs for adolescents, adult men, and adult women. Employing strategies such as 12-step facilitation, anger management techniques, and brief intervention methods, the center prioritizes personalized treatment plans. Seniors and adults looking for effective, customized addiction recovery will find dedicated support and high-quality care at TCN Behavioral Health Services Inc.

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TCN Behavioral Health Services Inc, located in Urbana, OH, delivers a full spectrum of therapeutic interventions for individuals battling addiction and dual diagnoses. The center features intensive outpatient, outpatient, and day treatment modalities, serving adults and older adults. TCN Behavioral Health Services Inc provides distinct programs for young people, adult males, and adult females, emphasizing personalized care plans. Their recovery strategies incorporate 12-step facilitation, anger management techniques, and concise interventions. Through dedicated tracks for men and women, TCN Behavioral Health Services Inc is committed to gender-informed care that enhances treatment effectiveness.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)