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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Talbert House
Cincinnati, OH

Situated in Cincinnati, OH, Talbert House provides both long-term and 24-hour residential treatment for substance use aimed at adult men and women. The center emphasizes 12-step programs, anger management techniques, and cognitive behavioral strategies. It features specialized programs designed for clients affected by intimate partner and domestic violence. Talbert House serves a diverse clientele of adults and young adults, creating an encouraging atmosphere for individuals on their recovery journey. Committed to delivering high-quality and evidence-based care, this facility strives to support individuals in overcoming addiction and restoring their lives.

Talbott Recovery Campus

Situated in Atlanta, Georgia, Talbott Recovery Campus provides extensive support for individuals battling substance use disorders. Their specialized programs cater to adults and young adults, with a particular emphasis on those who have endured trauma. Clients can access various levels of care, including intensive outpatient services, day treatment, and supportive living environments such as sober homes and halfway houses. Talbott Recovery Campus utilizes proven therapeutic methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing to guide individuals toward recovery. The center's commitment to gender-specific treatment ensures a personalized approach designed for sustained healing and well-being.

Tallahassee Outpatient Annex

Situated in Tallahassee, FL, the Tallahassee Outpatient Annex provides targeted outpatient treatment for individuals dealing with substance abuse and concurrent mental health issues, serving both adults and children. Emphasizing techniques such as cognitive behavioral therapy, motivational interviewing, and brief intervention, this center delivers intensive outpatient programs, general outpatient services, as well as treatments involving methadone, buprenorphine, or naltrexone. The annex also features customized programs designed specifically for veterans, accommodating individuals of various ages and genders. Committed to offering exceptional care, the Tallahassee Outpatient Annex focuses on fostering a nurturing atmosphere for those in need of all-encompassing rehabilitation programs.

Tandem Health
Sumter, SC

Tandem Health, located in Sumter, SC, specializes in providing extensive outpatient services for adults dealing with substance use and co-existing severe mental health conditions, along with emotional challenges in children. This center features customized programs designed to address each individual's unique requirements, utilizing a variety of evidence-backed methodologies, such as cognitive behavioral therapy and motivational interviewing. Tandem Health caters to a diverse clientele, including adults and young adults across all gender identities, distinguished by its focus on tailored care and dedication to each client’s recovery journey. Whether individuals are looking for consistent outpatient assistance or medication-supported treatment, this facility emphasizes high-quality care and sustainable recovery for those facing addiction challenges.

Tangu Recovery
Atlanta, GA

Tangu Recovery in Atlanta, GA, delivers tailored substance abuse services for adults and young adults within an encouraging and nurturing setting. The facility features various treatment approaches like intensive outpatient, outpatient, and day programs. Emphasizing 12-step facilitation, anger resolution, and brief counseling, their curriculum serves individuals managing co-occurring mental health and addiction issues, alongside those with past trauma. Tangu Recovery's distinct programs for men and women guarantee individualized attention. Discover empathetic and successful treatment at this center committed to guiding individuals toward wellness.

TRS Promises Behavioral Care Inc

TRS Promises Behavioral Care Inc, located in Wimberley, TX, specializes in extensive addiction recovery services for both adults and young adults. This rehabilitation center offers detoxification, treatment for substance use disorders, and targeted support for individuals facing simultaneous substance use and significant mental health challenges. With a range of treatment options, including intensive outpatient, outpatient, and residential detox programs, TRS Promises Behavioral Care addresses diverse recovery needs. The facility utilizes a variety of methods such as 12-step programs, anger management, and brief intervention strategies to facilitate effective treatment. Unique programs are designed for active duty service members, as well as separate services for adult men and women. This center is dedicated to delivering personalized care to all clients, focusing on high-quality, customized treatment to promote sustainable recovery.

Tanana Chiefs Conference Inc

Tanana Chiefs Conference Inc in Fairbanks, AK is a treatment provider for adults and children facing substance use challenges and co-occurring mental health conditions. They offer a range of services including intensive outpatient, outpatient, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their approach incorporates 12-step facilitation, anger management, and brief intervention techniques. The center is equipped to assist clients with histories of trauma, sexual abuse, and adolescents, serving both male and female individuals. Tanana Chiefs Conference Inc provides personalized, evidence-based care aimed at fostering recovery.

Tal Behavioral Health

Situated in Beachwood, OH, Tal Behavioral Health delivers extensive treatment for substance use issues in both adults and young adults. The center offers a range of services, including intensive outpatient, outpatient, and day treatment programs, incorporating elements like 12-step facilitation, anger management, and brief therapeutic interventions. Designed to meet the unique needs of each individual, this facility prioritizes personalized care for both male and female clients. Tal Behavioral Health is recognized for its quality and tailored support, featuring a variety of treatment modalities and specialized programs, positioning it as a crucial resource for individuals seeking effective and empathetic addiction treatment solutions.

TPC Substance Use Outpatient Services

Situated in Amarillo, TX, TPC Substance Use Outpatient Services delivers focused outpatient care for individuals dealing with substance use issues and overlapping mental health conditions in both adults and children. The center employs strategies such as brief intervention, cognitive behavioral therapy, and community reinforcement in conjunction with vouchers to offer customized assistance to its clients, regardless of gender. Prioritizing individualized care, TPC Substance Use Outpatient Services is designed for adults and young adults who are in search of thorough support in an outpatient setting. If you or someone you know is in need of effective substance use treatment that emphasizes a tailored approach, this center is committed to facilitating a successful recovery journey.

Talbert House
Georgetown, OH

Talbert House, situated in Georgetown, OH, provides extensive addiction recovery programs for adults and older individuals. Their expertise encompasses detoxification, managing substance use disorders, and addressing dual diagnoses like significant mental health conditions and behavioral issues in youth. The program emphasizes personalized support, featuring intensive outpatient care, general outpatient services, and outpatient detoxification. Employing proven methods such as cognitive behavioral therapy, motivational interviewing, and anger management, Talbert House delivers a customized treatment experience, offering high-quality care to men and women pursuing sobriety.

TRC The Recovery Center
Oklahoma City, OK

Situated in Oklahoma City, OK, TRC The Recovery Center delivers an extensive array of services for addiction treatment. This establishment is known for its inpatient detoxification services in a hospital setting, round-the-clock inpatient support, and intensive outpatient programs. Its treatment methodologies are grounded in evidence-based practices like 12-step facilitation, cognitive behavioral therapy, and brief interventions. TRC The Recovery Center features specialized programs tailored for adult men, adult women, and individuals who have faced trauma. Catering primarily to adults and young adults, the center offers gender-specific treatment options for both genders. TRC The Recovery Center is committed to providing exceptional, personalized care to assist individuals on their path to recovery.

Talbott at Dunwoody

Talbott at Dunwoody in Atlanta, GA, delivers extensive addiction care for adults and young adults, including detoxification and substance abuse therapy. Their programs encompass intensive outpatient, standard outpatient, and day treatment options. The center employs strategies such as 12-step facilitation, anger management, and brief interventions. They serve adult men and women, including those with histories of sexual abuse. Talbott at Dunwoody is dedicated to providing personalized care and robust support to each individual, guaranteeing superior treatment quality. For those needing assistance for themselves or someone else, this facility provides tailored programs and a nurturing atmosphere conducive to healing.

TPC Wellness
Jackson, OH

TPC Wellness, located in Jackson, OH, is dedicated to providing targeted substance use treatment specifically for adult males. This center features a variety of programs including intensive outpatient, outpatient, and day treatment formats. Emphasizing methods like 12-step facilitation, anger management, and cognitive behavioral therapy, TPC Wellness ensures that clients receive the attention they need. While primarily serving adult men, the facility also accommodates adult women and individuals living with HIV or AIDS, offering customized care to meet different requirements. Catering to adults, seniors, and young adults alike, this center focuses on delivering high-quality, personalized treatment strategies. For those in search of an inclusive addiction recovery program with an emphasis on male participants, TPC Wellness provides a nurturing space for healing and growth.

TRI Center Inc
Brooklyn, NY

TRI Center Inc, located in Brooklyn, NY, specializes in providing treatment for adults and young adults facing substance use challenges alongside significant mental health concerns or emotional issues. The center offers a variety of programs, including intensive outpatient, outpatient, and standard outpatient treatments. Its approach includes anger management, cognitive behavioral therapy, and motivational incentives, allowing for customized care to meet each individual's needs. The facility features distinct programs catering to adult men, women, and those with histories of sexual trauma, ensuring thorough support for various groups. TRI Center Inc is dedicated to delivering high-quality, individualized care, making it a reliable choice for effective rehabilitation services.

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Ironton, OH

Situated in Ironton, OH, TPC Wellness is a prominent rehabilitation facility focused on providing substance use treatment specifically for adult women. The center offers various programs, including intensive outpatient, outpatient, and day treatment services, employing proven methods like 12-step facilitation, cognitive behavioral therapy, and anger management. TPC Wellness is distinguished by its targeted programs for adult women, as well as individuals living with HIV or AIDS and those facing dual diagnoses involving mental health and substance use issues. Catering to adults, seniors, and young adults, the center delivers holistic care designed to meet the distinct needs of female clients, ensuring effective treatment and support.

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Mount Orab, OH

TPC Wellness, situated in Mount Orab, OH, stands out as a leading rehabilitation facility focused on substance use recovery for adult males. The center offers a variety of programs including intensive outpatient treatment, traditional outpatient services, and daytime treatment options, all designed to foster a nurturing recovery atmosphere. Their approach integrates 12-step principles, anger management techniques, and cognitive behavioral therapy to meet the diverse needs of clients. TPC Wellness serves adult men, seniors, and young adults, with specialized programs available for those living with HIV or AIDS, as well as individuals facing dual mental health challenges. Renowned for its exceptional care and personalized treatment strategies, this center is committed to guiding individuals on their journey toward enduring sobriety.

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TREE House for Women, situated in Albany, NY, is a distinguished facility dedicated to providing extensive residential care for adult women, including seniors. The center features tailored interventions for individuals impacted by intimate partner violence, domestic abuse, and sexual assault. Through techniques such as anger management, cognitive behavioral therapy, and motivational interviewing, they deliver thorough detoxification and treatment for substance use disorders alongside co-occurring mental health conditions. This program is specifically designed for young adults, fostering a nurturing atmosphere for women on their journey to recovery. TREE House for Women distinguishes itself through personalized support and scientifically validated methods, solidifying its reputation as a premier rehabilitation provider in the Albany region.

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New York, NY

TRI Center Inc located in New York, NY, provides dedicated rehabilitation services for individuals struggling with substance use disorders alongside co-occurring mental health challenges. Their offerings include intensive outpatient care, outpatient day programs, and partial hospitalization, catering specifically to both adults and young adults. Utilizing proven methodologies such as cognitive behavioral therapy and anger management, the center facilitates a thorough recovery process. TRI Center Inc emphasizes individualized treatment plans, offering specialized programs for adult men, adult women, and survivors of sexual abuse. Their dedication to high-quality care positions them as a trustworthy option for those in need of effective and customized rehabilitation solutions.

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TRI Center Inc, situated in the Bronx, NY, provides a wide array of treatment options for substance use disorders aimed at both adults and young adults. This center is particularly adept at addressing co-occurring substance use and severe mental health conditions in adults, in addition to managing significant emotional challenges in children. Treatment modalities available include intensive outpatient, outpatient, and standard outpatient programs, emphasizing personalized care through evidence-based techniques like cognitive behavioral therapy, anger management, and contingency management. The center also features targeted programs designed for adult men and women, as well as those affected by intimate partner or domestic violence. Committed to delivering high-quality care and tailored support, TRI Center Inc is dedicated to aiding individuals in their recovery journey.

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New York, NY

TRI Center Inc, located in New York, NY, provides both intensive outpatient and day treatment options for adults grappling with substance use disorders and serious co-existing mental health conditions. Their tailored programs serve adult men and women, including individuals who have faced sexual abuse. The center employs proven methodologies such as cognitive behavioral therapy and contingency management to tackle issues related to addiction and mental wellbeing. Emphasizing anger management techniques and motivational strategies, TRI Center Inc delivers thorough care for adults and young adults across all genders, aiming for exceptional recovery outcomes.

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Weatherford, TX

TX OTP LLC, situated in Weatherford, TX, delivers a full spectrum of addiction recovery solutions, encompassing medically supervised detox and ongoing substance use therapy. Their offerings include robust intensive outpatient programs, general outpatient services, and outpatient detox options. Employing scientifically validated methods like brief intervention, cognitive behavioral therapy, and contingency management, the center is equipped to assist active duty military members, adult men, adult women, and young adults. TX OTP LLC is committed to providing personalized care and encouragement for individuals navigating their path to sobriety, with tailored interventions for different genders and age demographics.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)