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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Turning Point Recovery Center Inc

Turning Point Recovery Center Inc located in Albuquerque, NM, provides a variety of thorough addiction recovery services. This facility focuses on treating substance use disorders while also offering transitional housing and sober living arrangements for both adults and young adults. The center features intensive outpatient and outpatient treatment options, including methadone and buprenorphine therapy. It emphasizes personalized care through methods such as 12-step facilitation, anger management, and short interventions. A key differentiator for this center is its customized treatment plans, designed to address the specific requirements of each individual. Furthermore, Turning Point Recovery Center Inc has dedicated programs for men and women, fostering a supportive and welcoming atmosphere for those on their recovery journey.

Turning Point Treatment Center

Turning Point Treatment Center in Dubuque, IA, delivers focused addiction recovery services for adults and adolescents. The program includes intensive outpatient services, standard outpatient care, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Utilizing therapeutic modalities such as brief intervention, cognitive behavioral therapy, and the Matrix Model, the center customizes plans for each person's unique circumstances. A core aspect of their philosophy is a personalized treatment strategy. Turning Point Treatment Center welcomes both male and female individuals, fostering a welcoming and inclusive setting. Clients can anticipate high-standard, research-backed methods to aid their path to wellness.

Twelve Oaks Recovery

Nestled in Navarre, FL, Twelve Oaks Recovery stands as a distinguished center dedicated to aiding individuals on their journey to overcome addiction. They offer extensive care, including inpatient detox and treatment for co-occurring mental health and substance use conditions in adults, alongside support for children with significant emotional challenges. Recognizing diverse needs, Twelve Oaks Recovery features targeted programs for active military members, adult men, and women. Employing methods like 12-step support, anger management, and brief therapeutic interventions, the center prioritizes individualized treatment plans. Serving adults and young adults across the gender spectrum, Twelve Oaks Recovery is devoted to providing effective, research-backed care aimed at fostering enduring recovery.

Twin Lakes Recovery Center

Twin Lakes Recovery Center, located in Monroe, GA, delivers an extensive array of services aimed at treating addiction for both adults and adolescents. The facility features detox services, options for substance use treatment, and tailored support for individuals facing both substance-related and mental health issues. Offering various treatment approaches such as intensive outpatient care, lengthy residential programs, and traditional outpatient services, Twin Lakes meets a wide spectrum of requirements. The center employs scientifically validated techniques, including cognitive behavioral therapy and contingency management, to guarantee top-notch care. Unique programs targeting those with simultaneous pain and substance use challenges, as well as specialized support for forensic clients, distinguish this center. Twin Lakes accommodates both men and women seeking reliable pathways to recovery.

Twin Town Treatment Centers

Situated in Los Alamitos, CA, Twin Town Treatment Centers delivers thorough substance abuse treatment for individuals of all ages, including adults, teens, and children. The center features intensive outpatient programs, standard outpatient services, and day treatment alternatives, emphasizing 12-step facilitation, brief intervention techniques, and cognitive behavioral therapy. Tailored programs are available for adolescents to address their specific requirements. Twin Town Treatment Centers values high-quality care, providing services to both men and women. Committed to using evidence-based methods, the facility fosters a nurturing atmosphere for those aiming to recover from addiction.

UCS Healthcare
Ankeny, IA

UCS Healthcare, located in Ankeny, IA, specializes in treatment for substance use disorders through a range of services such as intensive outpatient programs, standard outpatient care, and options for outpatient methadone, buprenorphine, or naltrexone therapy. The center employs various therapeutic techniques, including cognitive behavioral therapy, motivational interviewing, and anger management, to support both male and female adults, as well as individuals who have faced domestic or intimate partner violence. Catering to the needs of adults and young adults, UCS Healthcare focuses on personalized care designed to fulfill the distinct requirements of every client. Committed to high-quality, evidence-based treatment, the center strives to empower individuals on their path to recovery.

UCS Healthcare
Knoxville, IA

Located in Knoxville, IA, UCS Healthcare delivers targeted treatment for substance use through a range of options, including intensive outpatient services, outpatient care, and medication-assisted therapies. The center employs techniques such as anger management, cognitive behavioral therapy, and motivational interviewing to support adult men and women, including individuals with a history of trauma. By prioritizing both adult and young adult clients, UCS Healthcare offers personalized care designed for both genders. The facility's holistic methodology and customized treatment plans guarantee effective support for individuals striving to overcome substance use challenges.

Turning Point System of Care

In Kokomo, Indiana, Turning Point System of Care delivers a complete spectrum of care for those overcoming addiction and concurrent mental health challenges. Services include hospital-based inpatient detox, round-the-clock inpatient treatment, and outpatient programs. Employing scientifically validated methods such as cognitive behavioral therapy and anger management, the center serves adult men and women, and individuals with a history of trauma. Dedicated programs for adults and young adults ensure personalized attention and encouragement, creating a secure and supportive atmosphere conducive to healing and lasting sobriety.

Twin Town Treatment Centers
West Hollywood, CA

Situated in West Hollywood, California, Twin Town Treatment Centers delivers complete addiction recovery services designed for adults, adolescents, and young adults. They offer a spectrum of care including intensive outpatient, outpatient, and partial hospitalization programs. Utilizing proven methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center customizes treatment plans. Twin Town Treatment Centers also features dedicated support for the LGBTQ community. Committed to excellent care, this facility fosters a nurturing space for those pursuing sobriety, serving both men and women.

Twin Town Treatment Centers

Orange, CA's Twin Town Treatment Centers deliver targeted addiction care for individuals of all ages. They offer a spectrum of services including intensive outpatient, standard outpatient, and day treatment programs, encompassing partial hospitalization. Employing proven methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center welcomes both male and female patients. Twin Town Treatment Centers also feature distinct programs tailored for young people, ensuring high-quality, individualized support. For those in search of thorough and successful recovery solutions, this center provides a nurturing environment grounded in research-backed strategies.

Twins Bay Inc DBA Morro Bay Recovery

Twins Bay Inc DBA Morro Bay Recovery, located in Morro Bay, CA, provides extensive addiction recovery programs encompassing detox and ongoing substance use support. Their offerings include extended residential stays, on-site detoxification services, and continuous round-the-clock residential care. Through the application of methods like 12-step integration, emotional regulation techniques, and cognitive behavioral approaches, the center crafts individualized recovery plans. Catering to adult and young adult individuals, regardless of gender, Twins Bay Inc DBA Morro Bay Recovery emphasizes a customized path to healing. For those in search of expert care within a nurturing setting, this establishment is committed to delivering effective treatment to support enduring abstinence.

Twin Lakes Counseling Services

Situated in Leitchfield, KY, Twin Lakes Counseling Services provides a wide range of treatments for substance abuse and specialized support for individuals dealing with both substance use and severe mental health issues in adults, alongside significant emotional challenges in children. The center features intensive outpatient programs, outpatient services, and standard outpatient care, using proven strategies like 12-step facilitation, anger management, and short-term interventions. With tailored programs designed for active duty military personnel, teenagers, and adult men, Twin Lakes Counseling Services is dedicated to offering high-quality, personalized care for adults and seniors of all genders, ensuring that each individual’s specific needs are met.

Twin Town Treatment Centers

Twin Town Treatment Centers, situated in Torrance, CA, delivers a spectrum of care including intensive outpatient, outpatient, and day treatment options for individuals struggling with substance use disorders. Employing evidence-based strategies like 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center serves a diverse clientele, encompassing adults, children, and adolescents, and features distinct programs specifically designed for younger individuals. Twin Town Treatment Centers ensures personalized treatment plans for both male and female patients, emphasizing the delivery of effective, research-backed care. Dedicated to supporting individuals in their journey toward lasting recovery, this facility is distinguished by its thorough offerings and customized programs catering to different age brackets and genders.

Twin Town Treatment Centers

Situated in Sherman Oaks, CA, Twin Town Treatment Centers deliver extensive treatment for substance use disorders in both adults and teenagers. The facility offers various treatment plans, including intensive outpatient, outpatient, and day treatment programs, emphasizing 12-step facilitation, brief interventions, and cognitive behavioral therapy. Programs tailored specifically for adolescents provide focused support for younger clients. Twin Town is inclusive, accommodating both men and women, fostering a nurturing atmosphere for everyone. With a dedication to high-quality care and evidence-based practices, this center is recognized as a reliable option for individuals in need of effective and compassionate addiction recovery services.

Twelve1 Healthcare
Pell City, AL

Twelve1 Healthcare, located in Pell City, Alabama, provides a range of outpatient services focused on detoxification and treatment for substance use disorders. This center excels in offering counseling for substance use disorders, along with telehealth therapy options and outpatient treatments with methadone, buprenorphine, or naltrexone. Catering to various groups, including active duty military personnel, teenagers, and adult males, Twelve1 Healthcare ensures quality treatment for people of all genders. Individuals can access both detox services and continued support through the center's extensive programs and personalized recovery plans. If you or someone close to you requires assistance with addiction, Twelve1 Healthcare is committed to delivering effective support within a nurturing setting.

Tuscaloosa VA Medical Center

The Tuscaloosa VA Medical Center located in Tuscaloosa, Alabama, provides a diverse array of services for those dealing with addiction. The center offers detox services, treatment for substance use disorders, transitional housing, and options for halfway houses or sober living arrangements. Patients can access various treatment formats, including inpatient care, intensive outpatient programs, and around-the-clock inpatient support, designed for adult men and women as well as younger individuals. The facility also features specialized programs for individuals affected by domestic or intimate partner violence. Utilizing methods such as 12-step facilitation, anger management techniques, and brief interventions, the center ensures that care is customized to meet the unique needs of each client. Committed to delivering high-quality and personalized treatment, this center plays a vital role in aiding individuals on their journey to recovery.

UConnectCare
Batavia, NY

UConnectCare, situated in Batavia, NY, provides a wide range of detox and substance use treatment services. This center features residential detoxification along with 24/7 support for adults and young adults. Employing techniques such as brief intervention, cognitive behavioral therapy, and motivational interviewing, UConnectCare customizes treatment plans to meet the unique needs of each patient. Emphasizing individualized care, the center offers specialized programs for both men and women. Clients can look forward to receiving high-quality, evidence-based assistance in a nurturing setting. For those in search of effective addiction recovery that emphasizes personal care, UConnectCare is an excellent choice for your healing process.

UConnectCare Inc
Batavia, NY

UConnectCare Inc, located in Batavia, NY, provides a wide array of rehabilitation services designed to cater to various needs. Their offerings encompass treatments for substance use, as well as transitional housing options like halfway houses and sober living environments, available in formats such as long-term, 24-hour residential, and short-term stays. The center is proficient in several therapeutic methods, including anger management, brief intervention, and cognitive behavioral therapy, emphasizing personalized attention. UConnectCare Inc serves a diverse population of adults and young adults, regardless of gender, ensuring a secure and nurturing setting for those on the path to recovery. Their dedication to high-quality care and customized programs positions them as a leading option for individuals striving to overcome addiction.

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Turning Point Recovery Center Inc, located in Albuquerque, NM, provides a variety of specialized services designed for those in need of addiction rehabilitation. This center features intensive outpatient programs, as well as standard outpatient services, along with treatments utilizing methadone, buprenorphine, or naltrexone. Their approach includes methods such as 12-step facilitation, anger management, and brief intervention, customized to meet the unique needs of each individual. Catering to adults and young adults of all genders, the center emphasizes personalized care. Additionally, Turning Point Recovery Center Inc offers transitional housing, halfway house, and sober living arrangements, making it a well-rounded option for individuals seeking effective support in their recovery journey.

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Twin Town Treatment Centers, located in Laguna Hills, CA, provides professional substance abuse treatment via intensive outpatient, outpatient, and day treatment services. The center focuses on 12-step methodology, brief interventions, and cognitive behavioral therapy, addressing the needs of both adult and adolescent populations. Featuring programs specifically designed for teenagers and customized services for males and females, this facility ensures a thorough approach to rehabilitation within a nurturing setting. Twin Town Treatment Centers emphasizes high standards of care and utilizes evidence-based methods to assist individuals in overcoming addiction and attaining sustainable recovery.

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Weatherford, TX

TX OTP LLC, situated in Weatherford, TX, delivers a full spectrum of addiction recovery solutions, encompassing medically supervised detox and ongoing substance use therapy. Their offerings include robust intensive outpatient programs, general outpatient services, and outpatient detox options. Employing scientifically validated methods like brief intervention, cognitive behavioral therapy, and contingency management, the center is equipped to assist active duty military members, adult men, adult women, and young adults. TX OTP LLC is committed to providing personalized care and encouragement for individuals navigating their path to sobriety, with tailored interventions for different genders and age demographics.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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