NWVCIL Logo
Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6711 results

Utah Addiction Centers
Eagle Mountain, UT

Utah Addiction Centers, located in Eagle Mountain, UT, delivers a full spectrum of scientifically validated therapies for those battling addiction and associated mental health challenges. They offer intensive outpatient, extended residential stays, and outpatient options, all customized for adult men, adult women, and survivors of domestic or intimate partner abuse. Emphasizing 12-step principles, anger control techniques, and short-term intervention strategies, the facility ensures personalized treatment for adults and young adults. Utah Addiction Centers is committed to delivering superior, empathetic support to foster enduring recovery and enhanced mental wellness.

VA Augusta Healthcare System

VA Augusta Healthcare System in Augusta, GA, provides extensive addiction treatment for adults and young adults. Their services encompass detoxification, substance abuse therapy, and management of co-occurring mental health and substance use disorders. They offer intensive outpatient, extended residential stays, and outpatient services. The center employs individualized treatment strategies incorporating 12-step facilitation, anger management techniques, and brief intervention methods. Distinct programs are available for adult men, women, and survivors of intimate partner or domestic violence, offering tailored support. This facility is committed to delivering gender-inclusive, high-quality care to aid individuals in their recovery journey.

VA Black Hills Healthcare System

Situated in Hot Springs, SD, the VA Black Hills Healthcare System provides an extensive range of rehabilitation services tailored for both adults and young adults. This center focuses on outpatient care for those dealing with substance use issues, co-occurring mental health disorders, and individuals recovering from trauma. It features targeted programs designed for men, women, and those with a history of trauma, incorporating methods such as 12-step facilitation, cognitive behavioral therapy, and short-term interventions. The facility also includes transitional housing and sober living arrangements, ensuring that clients receive high-quality care in a nurturing setting. Treatment options that are specific to gender are offered for both male and female participants.

VA Caribbean Healthcare System

Situated in San Juan, PR, the VA Caribbean Healthcare System provides an array of rehabilitation services aimed at helping adults and young adults facing challenges with substance use and concurrent mental health issues. The center features tailored programs for active duty members, female adults, and individuals who have experienced intimate partner violence. Offering inpatient detoxification and treatment, it implements methods like anger management, brief intervention, and cognitive behavioral therapy. Focused on personalized care, this center serves both men and women, ensuring top-notch treatment to foster recovery and well-being.

VA Central California Healthcare Sys

The VA Central California Healthcare Sys in Fresno, CA, delivers extensive support for adults and young adults battling addiction. Their offerings include hospital-based detox, residential stays, and outpatient care. Employing methods like anger management and cognitive behavioral therapy, this center addresses individuals facing both mental health and substance use challenges, with a particular emphasis on veterans. Tailored programs for men and women are available, promoting excellent care within a nurturing setting. For those seeking robust addiction treatment integrated with mental health services, this institution is committed to guiding individuals toward sustained wellness.

VA Central Western MA HCS

The VA Central Western MA HCS located in Leeds, MA, provides targeted rehabilitation services for both adults and young adults battling substance use disorders alongside mental health challenges. The facility features all-encompassing treatment options, including inpatient detoxification with round-the-clock support. Emphasizing cognitive behavioral therapy, anger management, and short-term interventions, the center customizes its approach to meet the unique needs of each patient. Special programs are available for adult men and women, including those with histories of sexual trauma. The center's commitment to high-quality, gender-sensitive care establishes it as an essential resource for individuals seeking compassionate and effective addiction recovery solutions.

VA Eastern CO HCS Denver VAMC
Colorado Springs, CO

VA Eastern CO HCS Denver VAMC, located in Colorado Springs, CO, delivers targeted rehabilitation programs for adults and young adults facing challenges related to substance use and concurrent serious mental health disorders or emotional issues. The center features a range of treatment options, including intensive outpatient programs, outpatient services, and medications such as methadone/buprenorphine or naltrexone. Emphasizing methods such as 12-step facilitation, anger management, and brief interventions, this facility is designed to assist individuals who have gone through trauma, intimate partner violence, domestic violence, and sexual assault. Committed to providing comprehensive care, VA Eastern CO HCS Denver VAMC serves both men and women on their path to recovery and personal growth.

VA Eastern Kansas Healthcare System

The VA Eastern Kansas Healthcare System, situated in Leavenworth, KS, delivers extensive substance abuse treatment for adults and younger individuals. This institution provides medical detoxification within a hospital setting, intensive outpatient care, and round-the-clock hospital inpatient services. The treatment methodology incorporates strategies like 12-step facilitation, anger management techniques, and brief intervention to tackle substance dependency and co-occurring mental health conditions. Specific support is available for adult women, as well as those who have endured intimate partner violence or sexual trauma. Prioritizing high-quality care, this center serves both men and women looking for dedicated rehabilitation.

VA Greater LA Healthcare System

The VA Greater LA Healthcare System, situated in North Hills, CA, presents a thorough suite of rehabilitative programs. Its expertise lies in treating substance abuse and co-occurring conditions affecting adults and children. The center delivers intensive outpatient services, day treatment, and partial hospitalization. Employing methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the establishment supports active duty military members, adult men, and women. Catering to adults and young adults of all genders, this institution guarantees superior care customized for each person's unique requirements, positioning it as a premier option for those desiring successful and individualized recovery support.

VA Greater LA Healthcare Systems

The VA Greater LA Healthcare Systems, situated in Los Angeles, CA, is dedicated to providing focused rehabilitation services for both adults and young adults facing challenges related to substance use alongside co-occurring mental health conditions. The facility offers a variety of treatment options including intensive outpatient programs, general outpatient care, and medication-assisted therapies like methadone/buprenorphine or naltrexone. Emphasizing methods such as 12-step facilitation, cognitive behavioral therapy, and short-term interventions, this center customizes its approach to meet each individual's specific requirements. Additionally, it features specialized programs for active duty military members, LGBTQ individuals, and those with co-occurring issues, ensuring an all-encompassing treatment experience. The center is committed to providing high-quality support to both male and female clients on their journey to recovery.

VA Healthcare Systems of Connecticut

Situated in West Haven, CT, the VA Healthcare Systems of Connecticut delivers extensive addiction treatment services for both adults and elderly individuals. This center features inpatient detoxification services, around-the-clock care, and intensive outpatient programs. Emphasizing 12-step methodologies, anger management, and short-term interventions, it customizes treatment plans to tackle issues of substance abuse alongside dual mental health disorders. With a particular expertise in supporting veterans, the center provides tailored programs for men and women. The VA Healthcare Systems of Connecticut is committed to offering superior, personalized care to assist clients on their journey to recovery.

VA Hudson Valley Healthcare System

The VA Hudson Valley Healthcare System, situated in Montrose, NY, delivers extensive support for overcoming addiction. This location offers detoxification, comprehensive substance use disorder treatment, and tailored assistance for those facing both addiction and significant mental health challenges. Their program encompasses intensive outpatient, standard outpatient, and outpatient detoxification options. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, the facility welcomes adult men and women, including survivors of intimate partner or domestic violence. This center is committed to delivering excellent care and fostering recovery for adults and young adults alike.

VA Illiana Healthcare System

Located in Danville, IL, the VA Illiana Healthcare System delivers a wide array of services for addiction treatment. The facility specializes in detoxification, substance use therapy, and offers targeted support for individuals experiencing both substance use disorders and severe mental health issues, as well as emotional challenges in youth. With options including intensive outpatient care, long-term residential treatment, and general outpatient programs, the center customizes its services to meet the unique requirements of each individual. The use of techniques like anger management, brief interventions, and cognitive behavioral therapy fosters a comprehensive approach to healing. Furthermore, distinct programs aimed at active duty service members and veterans underscore the facility's dedication to supporting those who have served in the military. Catering to adults and young adults of all genders, the VA Illiana Healthcare System is committed to delivering quality care that prioritizes personalized treatment strategies.

VA Los Angeles Ambulatory Care Center

The VA Los Angeles Ambulatory Care Center in Los Angeles, CA, delivers extensive addiction recovery support for adults and younger individuals. This facility features intensive outpatient, standard outpatient, and outpatient detox options, employing strategies like 12-step encouragement, anger regulation, and short-term counseling. Targeted care is offered to active military members, adult men, and adult women. The center is committed to excellent care for those needing detox, substance abuse treatment, and support for dual diagnoses involving substance use and significant mental health conditions. Personalized recovery plans are central to their approach, serving both male and female patients in a welcoming and nurturing setting.

VA Maryland Healthcare System

The VA Maryland Healthcare System, located in Baltimore, MD, provides extensive recovery support for individuals, including young adults, struggling with addiction and related mental health challenges. Their services include medically supervised detoxification and inpatient care, utilizing therapeutic strategies like anger management techniques, brief intervention counseling, and cognitive behavioral therapy. Dedicated programs are available for active military personnel, adult men, and women, addressing their specific requirements. The facility's commitment to high-standard treatment and personalized recovery pathways is designed to offer patients the necessary assistance for enduring well-being.

VA Maryland Healthcare System

Situated in Perry Point, MD, the VA Maryland Healthcare System provides an extensive array of services aimed at addressing substance use disorders, transitional living, and co-existing mental health issues for both adults and children. This center offers both outpatient and residential treatment options, employing specialized methods that include 12-step processes, anger management strategies, and short-term interventions. Aimed particularly at clients who have faced trauma, dual diagnoses, and veterans, the center serves adults and young adults of all genders. With its commitment to high-quality care and customized treatment plans, this facility stands out as an excellent choice for those in need of effective and empathetic rehabilitation services.

VA Med/Jonathan M Wainwright Mem

The VA Med/Jonathan M Wainwright Mem center, situated in Walla Walla, WA, provides outpatient services for substance use disorders, emphasizing the treatment of adults with co-occurring serious mental health conditions and emotional issues in children. The center employs various therapeutic techniques, including anger management, cognitive behavioral therapy, and motivational interviewing, to deliver tailored care for veterans. This facility is committed to serving individuals of all ages and genders with outpatient options for methadone, buprenorphine, or naltrexone treatment. With a strong focus on personalized care and supporting individuals in their recovery journey, this center stands out in its quality of services.

Utah Partners for Health

Utah Partners for Health, located in West Jordan, UT, specializes in providing outpatient services for adults struggling with substance use and serious mental health disorders, as well as addressing emotional challenges in children. The center offers treatments using methadone/buprenorphine or naltrexone, along with consistent outpatient support. With customized strategies that include 12-step facilitation, anger management, and brief interventions, the facility serves both adult men and women, including active duty military members. Committed to serving individuals of all genders, Utah Partners for Health delivers high-quality care through a variety of programs and personalized treatment approaches.

Urban Recovery House LLC

Situated in Brooklyn, NY, Urban Recovery House LLC specializes in extensive substance use disorder treatments for adults coping with simultaneous mental health challenges. The center features both residential and short-term residential options that include anger management, brief intervention, and cognitive behavioral therapy. It offers tailored programs for adult men, adult women, and those who have faced issues related to intimate partner or domestic violence, ensuring a wide range of services for various backgrounds. Catering to adults and young adults of all genders, Urban Recovery House LLC prioritizes high-quality care within a nurturing setting, emphasizing personalized treatment strategies to foster enduring recovery and enhanced overall health.

Urban Recovery House LLC

Situated in Brooklyn, NY, Urban Recovery House LLC delivers exceptional detox services within a home-like atmosphere. This facility features round-the-clock support and tailored programs for active military members as well as adult males and females. Emphasizing 12-step principles, anger management, and concise intervention methods, Urban Recovery House LLC serves both adult and young adult clients from diverse backgrounds. The center's devotion to personalized care and extensive assistance positions it as a leading option for individuals pursuing successful addiction recovery in a secure and compassionate setting.

Utopia Health Center

Utopia Health Center, situated in Greenbelt, MD, provides extensive care for individuals of all ages grappling with substance abuse. They are adept at addressing dual diagnoses, where substance use disorder coexists with severe mental health conditions in adults or significant emotional challenges in young people. Services encompass intensive outpatient, standard outpatient, and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone. Their therapeutic framework incorporates proven methods like anger management, brief interventions, and cognitive behavioral therapy. Recognizing diverse needs, Utopia Health Center offers distinct programs for adolescents, adult men, and adult women, ensuring personalized recovery journeys for every client. Their commitment is to deliver high-quality support, fostering enduring recovery for both male and female patients.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)