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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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VA Northern Indiana Healthcare System

The VA Northern Indiana Healthcare System in Fort Wayne, IN, provides dedicated rehabilitation programs for individuals, encompassing adults and young adults, who are navigating the complexities of substance use disorders alongside co-occurring mental health challenges. Their offerings include structured intensive outpatient treatment, services for outpatient detoxification, and general outpatient care. Therapeutic modalities employed include 12-step facilitation, anger management techniques, and brief intervention strategies. The center is committed to delivering high-quality, personalized care specifically designed for veterans, offering robust support for both male and female patients. For those in search of scientifically supported treatment within a nurturing setting, this establishment represents a strong option for successful recovery.

VA Northern Indiana Healthcare System

Situated in Marion, IN, the VA Northern Indiana Healthcare System delivers extensive addiction treatment options for both adults and young adults. The facility is adept in detoxification, managing substance use issues, and addressing co-occurring mental health conditions. It features hospital inpatient services that emphasize 12-step processes, anger management strategies, and brief intervention techniques. With dedicated programs for veterans and services catering to all genders, the center is committed to providing excellent care for those on the path to recovery from substance abuse. It creates a nurturing atmosphere aimed at facilitating healing and personal development, whether addressing addiction or mental health challenges.

VA NY Harbor Healthcare System

The VA NY Harbor Healthcare System located in New York, NY offers a wide range of rehabilitation services aimed at supporting adults and young adults facing challenges from substance use disorders alongside mental health issues. The facility provides inpatient detoxification and treatment options, employing evidence-based methodologies such as 12-step support, anger management, and short counseling sessions. Specialized programs are available for adult men, adult women, and those who have faced sexual trauma. With an emphasis on personalized care, this center fosters a nurturing setting conducive to recovery. Programs designed specifically for men and women contribute to the success of individuals working to defeat addiction.

VA Pittsburgh Healthcare System

The VA Pittsburgh Healthcare System, situated in Pittsburgh, PA, offers an extensive array of outpatient services aimed at detoxification, treatment for substance use, and management of co-occurring disorders for both adults and children. This center is particularly dedicated to veterans, providing outpatient detox options as well as methadone and buprenorphine therapies. Emphasizing 12-step programs, anger management, and brief interventions, the facility serves both male and female adults, including young adults, who are looking for effective solutions for addiction and mental health issues. For veterans and civilians alike, this center may present an excellent opportunity for a supportive rehabilitation experience.

VA Portland Healthcare System

Located in Vancouver, WA, the VA Portland Healthcare System provides a wide array of services aimed at adults and seniors dealing with substance use issues alongside mental health challenges. The facility emphasizes intensive outpatient programs and detoxification services for those who need them. It specializes in care for adult women, trauma survivors, and individuals facing multiple disorders. The treatment methods utilized include 12-step facilitation, brief interventions, and cognitive behavioral therapy, all of which are designed to address the specific requirements of each client. The VA Portland Healthcare System is dedicated to delivering high-quality care, making it a reliable choice for people in search of addiction support and mental health assistance.

VA Puget Sound Healthcare System

The VA Puget Sound Healthcare System, situated in Tacoma, WA, delivers extensive recovery programs for adults and young adults struggling with addiction and related mental health challenges. Their offerings include intensive outpatient care, outpatient detox, and general outpatient services, all grounded in proven methods like cognitive behavioral therapy and contingency management. The center also features specialized tracks for adult men, adult women, and individuals with a history of trauma. Committed to high-quality, personalized treatment, this facility accommodates both male and female patients, fostering a nurturing atmosphere for those on their path to wellness.

VA Puget Sound Healthcare System

The VA Puget Sound Healthcare System, situated in Seattle, WA, delivers extensive substance abuse recovery programs for individuals of all ages. This institution offers tailored assistance for withdrawal management, addiction therapy, and concurrent mental health challenges. Services encompass inpatient hospital detox, structured outpatient programs, and round-the-clock hospital-based inpatient treatment. Employing research-backed methods like cognitive behavioral therapy and contingency management, the facility serves adult men and women, as well as survivors of sexual abuse. Its dedication to personalized care and high-standard rehabilitation makes it a premier destination for those pursuing successful recovery.

VA Roseburg Healthcare System

Situated in Roseburg, OR, the VA Roseburg Healthcare System delivers extensive programs for substance use recovery. This center features outpatient services such as methadone/buprenorphine or naltrexone therapy, standard outpatient sessions, and short-term interventions. The facility emphasizes cognitive behavioral therapy and motivational interviewing techniques. It also provides tailored programs for individuals who have faced trauma, including veterans. Adults and young adults of all genders can access high-quality care and specialized services offered here. If you or someone you know is in search of effective addiction treatment, the VA Roseburg Healthcare System is a commendable choice for customized, evidence-supported care.

VA Southern Nevada Healthcare System

At the VA Southern Nevada Healthcare System located in North Las Vegas, NV, individuals in need of intensive addiction recovery services can access focused treatment options. This center offers inpatient detoxification and care for those struggling with substance use disorders, including adults with co-occurring severe mental health issues and children facing significant emotional challenges. Emphasizing evidence-based methodologies such as cognitive behavioral therapy and anger management, the facility provides customized programs for adults and young adults across all gender identities. Specialized offerings are available for clients who have encountered trauma, domestic violence, intimate partner violence, or sexual abuse. Patients will receive premium, round-the-clock support in a nurturing setting at this esteemed institution.

Valiant Recovery
Punta Gorda, FL

Valiant Recovery, located in Punta Gorda, FL, provides a wide array of rehabilitation services for adults and young adults struggling with substance abuse and concurrent mental health challenges. The facility offers various treatment methods, including intensive outpatient, long-term residential, and outpatient programs, ensuring that it meets a broad spectrum of patient needs. Specialized programs are available for active duty military, as well as for adult men and women, allowing for customized care. Valiant Recovery employs methods like 12-step facilitation, anger management, and brief interventions to deliver effective, personalized support. With a commitment to serving individuals across different genders and age ranges, this center emphasizes holistic healing and bespoke treatment approaches.

Valle del Sol
Phoenix, AZ

Valle del Sol, situated in Phoenix, AZ, is a respected facility providing extensive support for those facing addiction and coinciding mental health challenges. They offer structured intensive outpatient programs, general outpatient services, and specialized medication-assisted treatment options including methadone, buprenorphine, and naltrexone. The center employs evidence-based approaches such as 12-step facilitation, anger management, and cognitive behavioral therapy. Valle del Sol is equipped to serve active duty military, adult men, and women, alongside adults, adolescents, and seniors of all genders, ensuring personalized care to foster lasting recovery.

Valle del Sol

Valle del Sol, situated in Mesa, AZ, delivers thorough care for substance abuse and targeted support for those facing dual mental health challenges. They offer a spectrum of treatment intensities, including intensive outpatient and standard outpatient services, alongside medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic framework incorporates scientifically validated methods like 12-step support, emotional regulation techniques, and cognitive behavioral interventions. Distinctive services are available for active military personnel, young people, and clients involved with the legal system. Catering to adults, youth, and older adults across all gender identities, Valle del Sol prioritizes personalized, high-quality recovery plans. Their commitment to unified care and a variety of specialized offerings underscores their mission to guide individuals toward lasting well-being.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, provides an array of specialized rehabilitation programs for adults struggling with substance use disorders alongside mental health challenges. The center features options for long-term, short-term, and residential treatments, utilizing proven methods such as 12-step programs, anger management techniques, and brief interventions. Valley Behavioral Health offers tailored programs for adult men, adult women, and those who have faced intimate partner or domestic violence, addressing the needs of diverse populations. Their services are designed to support adults, seniors, and young adults, ensuring individualized care for various age groups. This center is committed to delivering high-quality support that meets the specific needs of each person.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, provides various outpatient treatment options for individuals dealing with substance abuse, co-occurring mental health issues, and emotional challenges, catering to both adults and children. The center employs specific therapeutic methods, including cognitive behavioral therapy, anger management, and short-term intervention strategies. Valley Behavioral Health designs customized programs aimed at adult men and women and those who have faced trauma, addressing a wide spectrum of needs. This facility is committed to delivering high-quality care and support in a nurturing and inclusive atmosphere for adults and young adults of any gender pursuing recovery.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, delivers expert care for individuals struggling with addiction, co-occurring mental health conditions, and developmental challenges in youth. Their services encompass intensive outpatient and standard outpatient options, featuring methadone and buprenorphine assistance. Emphasizing techniques like anger management, cognitive behavioral therapy, and motivational interventions, the center supports adult men and women, including survivors of domestic abuse. Valley Behavioral Health is dedicated to providing comprehensive and individualized recovery support for adults and young adults of all genders.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, provides targeted long-term residential treatment aimed at addressing substance use issues and co-occurring serious mental health conditions in adults, alongside addressing significant emotional challenges in children. This center operates around the clock, offering comprehensive residential care that incorporates evidence-based methods such as 12-step programs, anger management techniques, and short-term interventions. Catering primarily to adult women and those who have faced intimate partner violence, domestic abuse, or sexual trauma, Valley Behavioral Health serves a diverse clientele, including adults, seniors, and young adults. The center emphasizes gender-specific programming to create a secure and nurturing atmosphere for female clients committed to their recovery journeys.

VA NY Harbor Healthcare System

The VA NY Harbor Healthcare System located in Brooklyn, NY, provides diverse treatment solutions for adults dealing with substance use issues and concurrent serious mental health disorders, as well as emotional challenges faced by children. The center features a variety of programs, including intensive outpatient services, long-term residential care, and traditional outpatient treatment, employing methodologies like 12-step programs, anger management techniques, and brief intervention strategies. It also offers specialized services for adult men, women, and individuals who have suffered from sexual abuse. This facility serves both adult and young adult populations, delivering personalized care with an emphasis on high-quality, evidence-based interventions.

Valle Vista Hospital

Valle Vista Hospital in Greenwood, IN, delivers a full spectrum of addiction recovery programs for individuals of all ages grappling with substance dependence and concurrent mental health challenges. The center features inpatient hospital detoxification and therapeutic care, along with tailored programs designed for young people, those who have experienced trauma, and individuals managing co-occurring illnesses. Employing proven therapeutic methods such as cognitive behavioral therapy and motivational incentives, Valle Vista Hospital guarantees high-standard support for both male and female patients. Prioritizing brief intervention and customized recovery strategies, this institution is a reliable destination for those pursuing impactful and empathetic rehabilitation.

Valle Wide Health Systems

Valle Wide Health Systems in La Junta, CO, delivers extensive support for those battling addiction, serving adults and older adults. Their offerings include outpatient detox, medication-assisted treatment with methadone or buprenorphine, and temporary living arrangements. Emphasizing cognitive behavioral approaches, techniques for managing anger, and concise intervention strategies, they tailor each person's path to healing. Valle Wide Health Systems provides distinct services for active military personnel, teenagers, and adult males, acknowledging their specific challenges. Catering to both men and women, the center is dedicated to providing superior, scientifically-backed treatment to foster lasting recovery.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health in Salt Lake City, UT, delivers targeted outpatient care for individuals struggling with substance abuse and co-occurring severe mental health issues, alongside emotional challenges in youth. Their therapeutic methods encompass strategies like anger control, cognitive restructuring, and concise therapeutic interventions. Recognizing the unique needs of adult men and women, as well as survivors of sexual trauma, Valley Behavioral Health crafts individualized treatment plans. The center also offers flexible outpatient medication-assisted treatment, including methadone, buprenorphine, and naltrexone. Dedicated to exceptional and personal assistance, this clinic supports adult patients with empathy and professional skill.

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Valley Behavioral Health in Midvale, UT, provides dedicated long-term residential care for individuals struggling with substance use and co-occurring mental health issues, serving both adults and children. This center offers continuous around-the-clock support, employing proven methods like 12-step support, anger management techniques, and brief intervention strategies. They also feature specialized programs for adult women, including those affected by domestic violence or sexual trauma. Emphasizing care for adult women, seniors, and young adult females, Valley Behavioral Health is committed to delivering thorough, individualized support to foster lasting recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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