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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Valle del Sol
Phoenix, AZ

Valle del Sol, situated in Phoenix, AZ, is a respected facility providing extensive support for those facing addiction and coinciding mental health challenges. They offer structured intensive outpatient programs, general outpatient services, and specialized medication-assisted treatment options including methadone, buprenorphine, and naltrexone. The center employs evidence-based approaches such as 12-step facilitation, anger management, and cognitive behavioral therapy. Valle del Sol is equipped to serve active duty military, adult men, and women, alongside adults, adolescents, and seniors of all genders, ensuring personalized care to foster lasting recovery.

Valley Behavioral Health

Located in Riverton, UT, Valley Behavioral Health delivers extensive outpatient services for individuals dealing with substance use issues and related mental health challenges, serving both adults and children. The center features targeted programs designed for active duty military members, teens, and adult males. Emphasizing techniques such as anger management, cognitive behavioral therapy, and short-term interventions, the facility supports clients of all genders. Offerings include outpatient treatment options with methadone, buprenorphine, or naltrexone, along with standard outpatient services. Valley Behavioral Health is committed to delivering personalized care aimed at those in need of effective support for addiction and mental health.

Valley Behavioral Health
American Fork, UT

Valley Behavioral Health, located in American Fork, UT, specializes in extensive outpatient services for individuals facing substance use issues alongside mental health challenges, available for both adults and children. The center's offerings include anger management sessions, cognitive behavioral therapy, and targeted brief interventions, creating tailored treatment plans for each patient. With dedicated services for active duty military members, teenagers, and adult males, the facility meets a wide range of needs. Valley Behavioral Health welcomes clients of all genders and ages, fostering a nurturing atmosphere conducive to recovery. Their outpatient options, featuring methadone/buprenorphine or naltrexone treatments, demonstrate a strong dedication to evidence-supported approaches. Opt for this center for expert care and empathetic guidance throughout your healing process.

Valley Community Services Board

Nestled in Staunton, VA, Valley Community Services Board delivers thorough addiction recovery care for adults facing dual diagnoses of serious mental health conditions and for children with significant emotional challenges. The facility features robust intensive outpatient and standard outpatient services, incorporating medication-assisted treatments like methadone, buprenorphine, or naltrexone. Tailored programs address the specific needs of teenagers, adult men, and adult women, accommodating various demographics. Employing evidence-based strategies such as 12-step integration, emotional regulation training, and short-term therapeutic interventions, the center crafts personalized treatment plans. Valley Community Services Board is committed to delivering excellent and impactful rehabilitation to guide individuals toward sustained wellness.

Valley Healthcare System

Fairmont, WV's Valley Healthcare System delivers thorough substance use care to adults, youth, and young adults managing co-occurring severe mental health challenges. This facility offers intensive outpatient, standard outpatient, and medication-assisted treatment including methadone, buprenorphine, or naltrexone. Their tailored approach includes anger management, brief intervention, and cognitive behavioral therapy. Valley Healthcare System welcomes both male and female individuals, fostering an encouraging and accommodating space for everyone pursuing effective rehabilitation.

Valley Healthcare System

Valley Healthcare System in Fairmont, WV, provides extensive addiction recovery services for individuals of all ages. Their expert treatment options encompass detoxification, management of substance dependence, and care for individuals facing both mental health conditions and substance use challenges. Available in long-term residential, detox residential, and round-the-clock residential settings, this center delivers personalized support through methods like 12-step encouragement, emotional regulation techniques, and cognitive behavioral strategies. Tailored services are available for adult males, adult females, and clients experiencing dual diagnoses. Catering to adults, children, adolescents, and young adults, regardless of gender, Valley Healthcare System is dedicated to exceptional, nurturing care.

Valle del Sol

Valle del Sol, situated in Mesa, AZ, delivers thorough care for substance abuse and targeted support for those facing dual mental health challenges. They offer a spectrum of treatment intensities, including intensive outpatient and standard outpatient services, alongside medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their therapeutic framework incorporates scientifically validated methods like 12-step support, emotional regulation techniques, and cognitive behavioral interventions. Distinctive services are available for active military personnel, young people, and clients involved with the legal system. Catering to adults, youth, and older adults across all gender identities, Valle del Sol prioritizes personalized, high-quality recovery plans. Their commitment to unified care and a variety of specialized offerings underscores their mission to guide individuals toward lasting well-being.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, provides various outpatient treatment options for individuals dealing with substance abuse, co-occurring mental health issues, and emotional challenges, catering to both adults and children. The center employs specific therapeutic methods, including cognitive behavioral therapy, anger management, and short-term intervention strategies. Valley Behavioral Health designs customized programs aimed at adult men and women and those who have faced trauma, addressing a wide spectrum of needs. This facility is committed to delivering high-quality care and support in a nurturing and inclusive atmosphere for adults and young adults of any gender pursuing recovery.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, provides targeted long-term residential treatment aimed at addressing substance use issues and co-occurring serious mental health conditions in adults, alongside addressing significant emotional challenges in children. This center operates around the clock, offering comprehensive residential care that incorporates evidence-based methods such as 12-step programs, anger management techniques, and short-term interventions. Catering primarily to adult women and those who have faced intimate partner violence, domestic abuse, or sexual trauma, Valley Behavioral Health serves a diverse clientele, including adults, seniors, and young adults. The center emphasizes gender-specific programming to create a secure and nurturing atmosphere for female clients committed to their recovery journeys.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, provides an array of specialized rehabilitation programs for adults struggling with substance use disorders alongside mental health challenges. The center features options for long-term, short-term, and residential treatments, utilizing proven methods such as 12-step programs, anger management techniques, and brief interventions. Valley Behavioral Health offers tailored programs for adult men, adult women, and those who have faced intimate partner or domestic violence, addressing the needs of diverse populations. Their services are designed to support adults, seniors, and young adults, ensuring individualized care for various age groups. This center is committed to delivering high-quality support that meets the specific needs of each person.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, specializes in offering comprehensive long-term residential care for adults dealing with substance use issues and serious mental health disorders, as well as addressing emotional challenges in children. This center provides round-the-clock support, emphasizing techniques such as 12-step programs, brief interventions, and cognitive behavioral approaches. The facility features distinctive programs aimed at adult men and those who have experienced intimate partner violence, domestic violence, or sexual abuse. With services designed for adults, seniors, and young adults, Valley Behavioral Health ensures a secure and nurturing atmosphere specifically for male clients, delivering exceptional care and targeted treatment for a range of complex issues.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, delivers expert care for individuals struggling with addiction, co-occurring mental health conditions, and developmental challenges in youth. Their services encompass intensive outpatient and standard outpatient options, featuring methadone and buprenorphine assistance. Emphasizing techniques like anger management, cognitive behavioral therapy, and motivational interventions, the center supports adult men and women, including survivors of domestic abuse. Valley Behavioral Health is dedicated to providing comprehensive and individualized recovery support for adults and young adults of all genders.

Valle Vista Hospital

Valle Vista Hospital in Greenwood, IN, delivers a full spectrum of addiction recovery programs for individuals of all ages grappling with substance dependence and concurrent mental health challenges. The center features inpatient hospital detoxification and therapeutic care, along with tailored programs designed for young people, those who have experienced trauma, and individuals managing co-occurring illnesses. Employing proven therapeutic methods such as cognitive behavioral therapy and motivational incentives, Valle Vista Hospital guarantees high-standard support for both male and female patients. Prioritizing brief intervention and customized recovery strategies, this institution is a reliable destination for those pursuing impactful and empathetic rehabilitation.

Valle Wide Health Systems

Valle Wide Health Systems in La Junta, CO, delivers extensive support for those battling addiction, serving adults and older adults. Their offerings include outpatient detox, medication-assisted treatment with methadone or buprenorphine, and temporary living arrangements. Emphasizing cognitive behavioral approaches, techniques for managing anger, and concise intervention strategies, they tailor each person's path to healing. Valle Wide Health Systems provides distinct services for active military personnel, teenagers, and adult males, acknowledging their specific challenges. Catering to both men and women, the center is dedicated to providing superior, scientifically-backed treatment to foster lasting recovery.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, located in Salt Lake City, UT, provides an extensive array of outpatient services for substance use disorders. This center is particularly adept at addressing co-occurring addiction issues and significant mental health challenges in adults, as well as emotional issues in children. Utilizing evidence-based practices such as anger management, cognitive behavioral therapy, and short-term interventions, the facility is designed for those in search of specialized assistance. Notable programs are available for active military members, teenagers, and adult males. Valley Behavioral Health delivers high-quality, personalized care for individuals of all ages and genders.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health in Salt Lake City, UT, delivers targeted outpatient care for individuals struggling with substance abuse and co-occurring severe mental health issues, alongside emotional challenges in youth. Their therapeutic methods encompass strategies like anger control, cognitive restructuring, and concise therapeutic interventions. Recognizing the unique needs of adult men and women, as well as survivors of sexual trauma, Valley Behavioral Health crafts individualized treatment plans. The center also offers flexible outpatient medication-assisted treatment, including methadone, buprenorphine, and naltrexone. Dedicated to exceptional and personal assistance, this clinic supports adult patients with empathy and professional skill.

Valley Healthcare System

Valley Healthcare System, located in Kingwood, WV, delivers individualized outpatient care for adults managing substance use alongside mental health conditions, and for children experiencing significant emotional distress. The center focuses on clients who are dealing with the complexities of both mental health disorders and addiction. Their therapeutic methods encompass anger resolution, short-term counseling, and cognitive-behavioral techniques. Treatment options include outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside traditional outpatient therapy. Valley Healthcare System serves a diverse clientele of all genders and ages, prioritizing comprehensive wellness and recovery.

Valley Behavioral Health
Salt Lake City, UT

Valley Behavioral Health, situated in Salt Lake City, UT, specializes in treating substance use issues alongside co-existing mental health conditions for both adults and children. The center offers a variety of treatment formats including intensive outpatient, outpatient, and day programs. Emphasizing 12-step work, anger management, and brief intervention strategies, it serves adult individuals of all genders, including those who have faced trauma such as sexual abuse. By providing personalized care that meets the unique requirements of each client, Valley Behavioral Health aims to deliver effective rehabilitation solutions for those grappling with addiction and mental health concerns.

Valley Healthcare System

Valley Healthcare System, located in Morgantown, WV, provides extensive substance abuse treatment for individuals of all ages. Their offerings include robust intensive outpatient services, standard outpatient programs, and targeted outpatient care for those needing methadone, buprenorphine, or naltrexone. They integrate therapeutic strategies such as 12-step support, anger management techniques, and brief intervention methods, effectively addressing co-occurring mental health and substance use challenges. Programs are designed to serve both male and female patients, ensuring individualized attention. Valley Healthcare System is committed to delivering excellent, research-supported care in a supportive setting, guiding individuals toward lasting recovery.

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Valley Behavioral Health in Midvale, UT, provides dedicated long-term residential care for individuals struggling with substance use and co-occurring mental health issues, serving both adults and children. This center offers continuous around-the-clock support, employing proven methods like 12-step support, anger management techniques, and brief intervention strategies. They also feature specialized programs for adult women, including those affected by domestic violence or sexual trauma. Emphasizing care for adult women, seniors, and young adult females, Valley Behavioral Health is committed to delivering thorough, individualized support to foster lasting recovery.

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Valley Healthcare System, located in Grafton, WV, offers a wide range of outpatient treatment services for substance use issues, supporting both adults and children/adolescents who face co-existing mental health challenges. The center features tailored programs designed for individuals with dual diagnoses, utilizing proven methods such as cognitive behavioral therapy, anger management strategies, and brief intervention techniques. Committed to personalized care, Valley Healthcare System serves male and female clients alike, fostering a nurturing atmosphere. The facility provides services including outpatient methadone/buprenorphine and naltrexone treatments, alongside standard outpatient care, all aimed at delivering exceptional rehabilitation support to assist individuals in their recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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