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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Westchester Medical Center

Westchester Medical Center, situated in Poughkeepsie, NY, provides extensive outpatient treatment options for both adults and young adults dealing with substance use issues. The facility specializes in addressing co-occurring mental health conditions alongside substance use disorders. They utilize personalized treatment methods, including brief interventions, cognitive behavioral therapy, and motivational interviewing. With a particular emphasis on supporting clients who have faced trauma, Westchester Medical Center offers outpatient treatments involving methadone, buprenorphine, or naltrexone, alongside general outpatient services. Serving a diverse clientele of both men and women, the center is dedicated to delivering high-quality, individualized care to aid individuals in their recovery journey.

Western Illinois University

Situated in Macomb, IL, Western Illinois University provides outpatient treatment for substance use issues, catering to both adults and minors. The program incorporates various strategies, including anger management, short-term interventions, and cognitive behavioral therapy, customized to meet individual needs. Prioritizing personalized care, the center serves clients of all genders. Western Illinois University distinguishes itself through its dedication to delivering top-notch, tailored treatment, establishing itself as a trustworthy option for effective, gender-sensitive rehabilitation services in the Macomb region.

Western PA Adult and Teen Challenge

Situated in Cheswick, PA, the Western PA Adult and Teen Challenge provides an array of substance abuse treatment options specifically for adult males. Emphasizing methods such as 12-step support, anger management, and brief intervention techniques, this center offers a range of services including intensive outpatient care, long-term residential stays, and regular outpatient programs. It serves adult males, older adults, and young individuals who have faced issues like intimate partner violence, domestic violence, or sexual abuse. The dedicated programs cater to these particular challenges, ensuring personalized support and care. With a focus on delivering high-quality treatment based on proven practices, this center is committed to guiding clients through their recovery journey.

Western Psychological and

Western Psychological is a comprehensive substance use rehabilitation facility located in Gladstone, OR. It offers a range of treatment options, including intensive outpatient programs, outpatient services, and standard outpatient care. The center employs a variety of methodologies, such as 12-step facilitation, brief interventions, and cognitive behavioral therapy. Specialized programs are available for adolescents, individuals with dual diagnoses of mental health and substance use disorders, and those experiencing both chronic pain and substance use issues. The services provided are designed to accommodate adults, children and adolescents, as well as seniors of all genders. Western Psychological prioritizes high standards of care, emphasizing personalized treatment strategies and evidence-based approaches to foster effective recovery.

Western Arkansas Counseling and

Western Arkansas Counseling, located in Fort Smith, AR, delivers outpatient treatment for substance use issues affecting both adults and children who are also facing co-occurring mental health disorders. The center features tailored programs specifically designed for active duty military members, teenagers, adult men, as well as being inclusive of both men and women. Among the various treatment methods employed are 12-step facilitation, anger management sessions, and short intervention strategies. Committed to delivering high-quality care, this facility offers outpatient services that include methadone/buprenorphine or naltrexone treatments, alongside regular outpatient care. Aimed at supporting adults and seniors, the center focuses on providing thorough assistance to those pursuing recovery from substance use and related mental health challenges.

Western Arkansas Counseling and

Western Arkansas Counseling and offers extensive outpatient care in Fort Smith, AR. We focus on helping individuals overcome addiction through detoxification, substance use disorder treatment, and specialized support for co-occurring mental health issues in adults and emotional challenges in children. Our services include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient programs. We utilize proven therapeutic methods such as 12-step facilitation, anger management, and brief interventions. Tailored programs are available for active military, teenagers, and adult men. We welcome adults and seniors of all genders, providing a supportive environment for healing and recovery.

Western Pacific Rehab

Western Pacific Rehab, situated in Glendale, CA, delivers outpatient care focused on detox and addiction recovery. Their services include outpatient detox and medication-assisted treatment with methadone, buprenorphine, or naltrexone, available to adult and young adult individuals of any gender. The treatment methodology incorporates 12-step support, anger management techniques, and brief intervention strategies. The center is dedicated to high-quality treatment and offers distinct programs for active military personnel, teens, and adult males. Western Pacific Rehab is devoted to offering personalized assistance to those pursuing effective and thorough addiction treatment.

Westcare Tennessee Treatment Facility

Westcare Tennessee Treatment Facility, located in Dandridge, TN, delivers complete care for adults battling substance use issues, particularly those with concurrent severe mental health conditions and emotional challenges in children. Their services extend to outpatient care, encompassing medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient support. The treatment philosophy incorporates evidence-based practices like 12-step program engagement, strategies for managing anger, and brief counseling interventions. The facility also features targeted programs for active military members, adult men, and women, addressing the specific needs of various groups. Catering to adults and young adults across all gender identities, Westcare Tennessee Treatment Facility is committed to providing excellent support and treatment for those pursuing recovery in a supportive setting.

Western Arkansas Counseling and

Situated in Ozark, AR, the Western Arkansas Counseling center delivers outpatient treatment for adults dealing with substance use disorders, which encompasses individuals facing concurrent serious mental health challenges. This center offers targeted support for active duty military, teenagers, and adult males. The treatment modalities include 12-step facilitation, anger management, and brief intervention strategies. With programs designed to meet the needs of both women and men, as well as senior citizens, this facility is committed to providing thorough care for a wide array of individuals. Clients seeking either consistent outpatient services or methadone/buprenorphine treatment can anticipate personalized, high-quality care here.

Western Health Community Clinics

Situated in Harbor City, CA, Western Health Community Clinics provides a full spectrum of outpatient services for addiction recovery, including detox and treatment for substance abuse. The center focuses on outpatient detox options, as well as therapies involving methadone, buprenorphine, or naltrexone, along with counseling for substance use disorders. With personalized programs designed for active military members and both adult men and women, this facility meets the needs of a wide array of clients. Western Health Community Clinics serves adults and young adults of all genders, delivering effective care and assistance for those aiming to conquer substance use challenges.

Western Mental Health Center

Western Mental Health Center, situated in Marshall, MN, delivers a full spectrum of support for those pursuing recovery from addiction and mental health challenges. They provide intensive outpatient and standard outpatient services, with particular attention to dual diagnosis for both youth and adults. Utilizing proven methods like cognitive behavioral therapy and anger management, Western Mental Health Center serves a diverse clientele across all age groups and genders. Their distinct offerings include personalized plans for teenagers and individuals managing both mental health conditions and substance dependency. Committed to excellence, this center is a reliable partner for anyone beginning their journey toward well-being.

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Westbrook Health Services in Spencer, WV, delivers complete addiction treatment for individuals of all ages facing significant mental health challenges. Their offerings include intensive outpatient services, general outpatient care, and targeted medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing therapeutic methods such as 12-step facilitation, anger management, and cognitive behavioral therapy, the center customizes treatment plans for each person. Westbrook Health Services is distinguished by its individualized approach, catering to adults and older adults regardless of gender. For those looking for proven, science-backed treatment within a nurturing setting, this center is committed to guiding you toward enduring sobriety.

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Pinellas Park, FL

Situated in Pinellas Park, FL, Westcare stands out as a leading rehabilitation facility focused on overcoming substance use disorders. The center provides various treatment options, including outpatient programs, methadone/buprenorphine, or naltrexone treatments, and structured outpatient services, ensuring a holistic approach to healing. Westcare employs evidence-informed strategies such as anger management, cognitive behavioral therapy (CBT), and motivational incentives to offer customized care for each client. The center features specialized programs for adult men and women, as well as those who have faced domestic or intimate partner violence, addressing a wide range of individual needs. Westcare is dedicated to offering top-notch, personalized treatment for adults and young adults across all genders to foster enduring recovery.

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Situated in Van Buren, AR, the Western Arkansas Counseling and Rehabilitation Center provides extensive outpatient services addressing substance use disorders and co-occurring mental health issues in adults, as well as serious emotional challenges in children. The center features tailored treatment options for active duty service members, teenagers, and adult men. Emphasizing 12-step programs, anger management, and short-term interventions, it serves clients of all genders and ages. The facility also offers outpatient treatments with methadone/buprenorphine or naltrexone, ensuring effective care and assistance for those pursuing recovery and wellness.

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Situated in Paris, AR, Western Arkansas Counseling provides a thorough outpatient program for individuals struggling with substance abuse and concurrent mental health challenges, catering to both adults and children. The center features dedicated services for active duty military personnel, teenagers, and adult males, ensuring personalized care for diverse populations. Employing methods like 12-step practices, anger management, and short-term interventions, this facility prioritizes complete wellness. It accommodates adults and seniors of any gender, highlighting the importance of quality treatment and customized plans to aid clients in their recovery process.

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Situated in Mena, AR, Western Arkansas Counseling and provides extensive outpatient care for substance use disorders affecting both adults and children who are also dealing with significant mental health challenges. The center features tailored services for active military personnel, teenagers, and adult males, accommodating diverse demographics. Patients can access outpatient treatment using methadone, buprenorphine, or naltrexone, alongside standard outpatient counseling. Employing therapeutic methods like 12-step facilitation, anger management, and brief interventions, the facility is committed to personalized recovery journeys. Western Arkansas Counseling and prioritizes high-quality, customized treatment strategies to foster enduring well-being.

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Western Arkansas Counseling and in Waldron, AR, provides a full spectrum of outpatient services for individuals of all ages who are struggling with substance use disorders, particularly when co-occurring with significant mental health challenges or emotional difficulties. Their therapeutic approaches incorporate evidence-based practices like 12-step facilitation, anger management, and brief intervention strategies. The center caters to specific populations including active military, teens, and adult men, while ensuring individualized care plans for all genders. They are committed to delivering high-quality support, offering outpatient medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, alongside traditional outpatient counseling for adults and older adults.

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Western Arkansas Counseling and, situated in Booneville, AR, delivers a thorough suite of outpatient services for individuals of all ages struggling with substance use disorders, especially when co-occurring with significant mental health challenges. Their commitment to excellent care is evident in their specialized offerings, including 12-step program support, techniques for managing anger, and brief counseling strategies. They feature distinct programs catering to active military, teenagers, and adult men. This center extends its outpatient care, including methadone, buprenorphine, or naltrexone options, to adults and older adults regardless of gender. Western Arkansas Counseling and is committed to aiding those on their journey toward lasting recovery.

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Western Montana Addiction Services, located in Missoula, MT, provides a wide range of outpatient treatment options for individuals struggling with substance use, including adults and children facing significant mental health challenges. The facility features tailored programs designed for active-duty military members as well as men and women. Treatment approaches include anger management techniques, cognitive behavioral therapy, and the use of motivational incentives. Emphasizing personalized care, this center serves both genders in their recovery journey. Whether through outpatient methadone/buprenorphine/naltrexone therapy or standard outpatient services, the focus remains on delivering high-quality support for both adults and youth requiring addiction recovery assistance.

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Situated in Anaconda, MT, Western Montana Tri County delivers focused treatment for individuals grappling with substance use and concurrent mental health issues, catering to both adults and children. The center offers outpatient services that feature methadone and buprenorphine therapies while ensuring personalized support through programs like anger management, cognitive behavioral therapy, and motivational incentives. Custom-designed programs for active duty military personnel, as well as for adult men and women, provide thorough assistance. This facility serves adults and young adults across all genders and emphasizes the use of evidence-based methods to facilitate sustainable recovery. Western Montana Tri County is committed to offering superior care and guidance for those seeking assistance with addiction and mental health difficulties.

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Western Psychological offers complete addiction recovery services in Beaverton, Oregon. Their offerings include intensive outpatient, outpatient, and standard outpatient programs. The center employs approaches such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. They serve adults, youth, and older adults across all genders. Distinctive services for adolescents, individuals facing dual mental health and substance use challenges, and those with co-occurring pain and addiction issues highlight their specialized care. Western Psychological's individualized strategies and dedication to high-standard treatment make it an excellent option for those desiring impactful and customized addiction support.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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