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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Will Work for Recovery
Minneapolis, MN

"Will Work for Recovery" in Minneapolis, MN, provides outpatient services for adults and seniors dealing with substance use issues. The center focuses on methods such as 12-step facilitation, anger management, and brief interventions. It offers customized programs for adult men, adult women, and individuals who have faced trauma, ensuring personalized care that addresses various needs. Catering to both male and female clients, the facility fosters a nurturing atmosphere. Dedicated to high-quality rehabilitation, "Will Work for Recovery" is recognized for its extensive treatment options and emphasis on tailored recovery experiences.

Willapa Behavioral Health and Wellness

Willapa Behavioral Health and Wellness, situated in Long Beach, WA, is a holistic rehabilitation facility dedicated to addressing substance use disorders along with coexisting mental health issues. The center offers a variety of programs, including intensive outpatient and standard outpatient care, as well as methadone/buprenorphine or naltrexone treatment options. Emphasizing techniques like anger management, brief intervention, and cognitive behavioral therapy, this center customizes its services according to each person's unique circumstances. Specialized programs are available for individuals affected by intimate partner violence, domestic violence, and legal challenges. Catering to adults and seniors of any gender, this center is committed to providing top-notch care and guidance for those on their recovery journey.

Willapa Behavioral Health and Wellness

Willapa Behavioral Health and Wellness, situated in Raymond, WA, offers extensive support for individuals grappling with addiction and co-occurring mental health challenges, serving both younger and adult populations. Their treatment options include structured intensive outpatient care, standard outpatient services, and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Employing evidence-based methods such as anger management, motivational interviewing, and cognitive behavioral therapy, they personalize recovery plans. The center also provides dedicated support for those affected by intimate partner violence, domestic abuse, and legal system involvement. Willapa Behavioral Health and Wellness is committed to providing compassionate and effective care to adults and seniors of all backgrounds on their journey to wellness.

William Bill Kling
Fort Lauderdale, FL

The William Bill Kling Rehabilitation Center, situated in Fort Lauderdale, FL, specializes in providing treatment for detoxification, substance abuse, and co-occurring disorders for both adults and children. Offering a range of outpatient services such as detox programs, methadone and buprenorphine therapy, and a variety of therapeutic methods including 12-step facilitation and anger management, this center addresses the specific needs of adult men and women, seniors, and individuals who have faced intimate partner violence. It emphasizes personalized care for all clients, striving for excellence in treatment through short intervention strategies. For those in search of comprehensive and empathetic rehabilitation options, this center is committed to facilitating your path to recovery.

William J McCord
Orangeburg, SC

Situated in Orangeburg, SC, the William J McCord Rehabilitation Center specializes in delivering extensive support for those facing challenges related to substance abuse and accompanying mental health issues. This center offers targeted treatment options for adults dealing with severe mental health disorders, as well as support for children experiencing emotional difficulties and teenagers in need of assistance. Emphasizing evidence-based techniques such as cognitive behavioral therapy and motivational interviewing, the center also provides tailored programs aimed at managing anger. With services including hospital inpatient detox and around-the-clock care, this facility accommodates both male and female patients of various ages. Anticipate exceptional care and customized treatment strategies at the William J McCord Rehabilitation Center.

William S Middleton Veterans Hosp

Situated in Madison, WI, the William S Middleton Veterans Hosp presents an extensive array of treatment solutions for those striving to overcome substance abuse challenges. This facility delivers inpatient detoxification and treatment services, along with transitional housing and sober living assistance. Emphasizing 12-step programs, anger management, and brief intervention techniques, the center serves adult men and women, including younger adults. Tailored programs are also offered for individuals who have faced trauma and those dealing with co-occurring mental health issues. The center's gender-specific treatment model ensures that each individual receives customized care and support, highlighting a dedication to high-quality and effective rehabilitation services.

Williamsburg Place
Williamsburg, VA

Situated in Williamsburg, VA, Williamsburg Place delivers an extensive array of services for addiction recovery. The center specializes in detoxification and treatment for substance use, offering options such as residential detox, 24/7 residential care, and short-term residential programs. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, this facility serves adult men and women, including those in active military service. Customized programs for both young adults and older adults guarantee individualized attention. Williamsburg Place is distinguished by its dedication to high-quality care and specialized treatment plans, making it a leading choice for those in need of effective and compassionate addiction support.

Williamsville Wellness Center

Situated in Hanover, VA, Williamsville Wellness Center delivers exceptional substance use rehabilitation in a cozy residential environment. The center incorporates 12-step facilitation, anger management, and brief intervention methods into its treatment program. It serves adult men and women, including those who have faced intimate partner or domestic violence. Williamsville Wellness Center is dedicated to supporting adults and young adults of all genders, offering continuous assistance during short-term residential programs. Emphasizing high-quality care and personalized treatment plans, this facility is recognized for its extensive services and customized approaches to facilitate the recovery process.

Willows at Red Oak Recovery

Willows at Red Oak Recovery in Fletcher, NC, delivers targeted treatment for adult women struggling with addiction and co-occurring severe mental health conditions. Their offerings include intensive outpatient, extended residential stays, and outpatient care, all customized for adult women with a history of intimate partner abuse. The center employs 12-step facilitation, anger management techniques, and cognitive behavioral therapy to deliver holistic support in a secure and nurturing setting. Catering to a diverse age range from seniors to young adults, Willows at Red Oak Recovery is distinguished by its high-caliber treatment and specific care for its female clientele.

Wilmington Treatment Center

Wilmington Treatment Center, situated in Wilmington, NC, delivers extensive rehabilitation options for both adults and young adults facing challenges with substance abuse and related mental health issues. This center features tailored programs for active duty military personnel, as well as separate provisions for adult men and women. It offers hospital-level inpatient detox services and treatment, employing methodologies such as the 12-step approach and anger management techniques. Prioritizing personalized care and using evidence-based methods like brief interventions, the center ensures high-quality care for all clients. If you or someone you care about is looking for reliable and compassionate addiction treatment, Wilmington Treatment Center is committed to guiding you toward a successful recovery.

Windmill Wellness Ranch

At Windmill Wellness Ranch in Canyon Lake, TX, we provide an all-encompassing suite of addiction recovery programs, encompassing detox, substance abuse therapy, temporary housing, and sober living options. Our facility offers inpatient medical detoxification and treatment, with tailored programs designed for active military members, adult men, and women. Employing proven therapeutic methods such as 12-step support, emotional regulation techniques, and cognitive behavioral therapy, we serve individuals of all ages, from youth to adults. Our commitment to high-quality care and personalized treatment strategies makes Windmill Wellness Ranch a reliable choice for individuals pursuing successful rehabilitation in a nurturing setting.

Wilmot Family Health

Wilmot Family Health, situated in Tucson, Arizona, specializes in outpatient treatment for substance use for both adults and children who are simultaneously facing significant mental health challenges. The center employs various therapeutic techniques, including anger management and cognitive behavioral therapy, to deliver effective care through consistent outpatient appointments. Customized programs are designed for diverse groups, including active duty military members, men and women of all ages, and seniors. Emphasizing personalized care, the center cultivates a nurturing atmosphere for individuals committed to addressing substance use issues and mental health difficulties.

Williamson Health and Wellness Center

The Williamson Health and Wellness Center in Williamson, WV, provides targeted outpatient care for individuals struggling with substance use disorders and co-occurring mental health challenges. They also support children with serious emotional disturbances. Their approach emphasizes personalized treatment plans, incorporating techniques such as anger management, brief interventions, and cognitive behavioral therapy. Programs are designed to meet the specific needs of adults and seniors, serving both men and women. Services include outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone) alongside standard outpatient therapy. The Williamson Health and Wellness Center is dedicated to delivering high-quality, compassionate rehabilitation services in a nurturing setting.

Willow Tree Recovery
Pleasant Grove, UT

Situated in Pleasant Grove, UT, Willow Tree Recovery is a prominent rehabilitation facility focused on addressing substance use issues. The center offers a variety of programs, including both long-term and short-term residential options, as well as around-the-clock support, catering to both adult males and females. What sets Willow Tree Recovery apart is its customized treatment methods, which encompass 12-step facilitation, anger management, and cognitive behavioral therapy. Additionally, the center is equipped to assist clients dealing with both mental health and substance use disorders, ensuring a holistic treatment approach. With an emphasis on high-quality, personalized care, Willow Tree Recovery is committed to guiding clients towards sustainable recovery.

Wilmington Mental Health

Situated in Wilmington, NC, Wilmington Mental Health is dedicated to offering a variety of outpatient programs aimed at addressing substance abuse and co-existing mental health issues in both adults and children. The center is equipped to provide customized treatment for specific groups, including military personnel, teenagers, and adult males. The therapeutic methods employed include cognitive behavioral therapy, anger management, and brief intervention strategies. Prioritizing high-quality treatment, this facility offers outpatient options for methadone/buprenorphine and naltrexone, alongside standard outpatient care. Wilmington Mental Health is committed to delivering thorough and efficient rehabilitation services to those tackling addiction and mental health struggles, catering to both men and women.

Willow Creek Behavioral Health

Willow Creek Behavioral Health in Green Bay, WI, delivers thorough detox programs for adults and young people. They offer inpatient hospital detox with constant care for individuals requiring significant assistance. Willow Creek specializes in short-term interventions and cognitive behavioral therapy, serving clients facing both mental health and substance use challenges. The facility welcomes everyone, providing customized treatment plans for every patient. Willow Creek Behavioral Health is recognized for its dedication to excellent care and treatments proven to work, positioning it as a leading option for those desiring successful recovery services near Green Bay.

Willowbrooke at Tanner

Situated in Villa Rica, GA, Willowbrooke at Tanner is an all-encompassing rehabilitation facility that delivers focused treatment options for detox, substance abuse, and concurrent mental health challenges in both adults and children. The center offers inpatient hospital services, featuring round-the-clock care, and employs proven techniques such as cognitive behavioral therapy and anger management strategies. Willowbrooke at Tanner is notable for its customized programs designed specifically for teenagers and those facing dual diagnoses. Committed to delivering high-quality care, this center supports both male and female clients, fostering a nurturing space for recovery and wellness.

Willowbrooke at Tanner

Willowbrooke at Tanner in Carrollton, GA, provides thorough and caring support for individuals facing addiction and related mental health concerns. The center specializes in treating both adults and young people grappling with substance use disorders and dual diagnoses. Through various levels of care, such as intensive outpatient, standard outpatient, and day treatment programs, they employ proven therapeutic methods. These include techniques like anger management, cognitive behavioral therapy, and brief intervention strategies. Willowbrooke at Tanner caters to the unique needs of adolescents and those experiencing co-occurring mental health conditions, offering gender-inclusive programs. Rely on their skilled professionals to support your journey toward sustained recovery and enhanced health.

Windham Center
Bellows Falls, VT

Windham Center, situated in Bellows Falls, VT, delivers thorough care for adults and children facing addiction, substance abuse, and concurrent mental health concerns. This establishment provides inpatient hospital detoxification and treatment, featuring distinct programs for individuals with dual diagnoses. Utilizing proven methods such as 12-step support, anger management strategies, and brief intervention, Windham Center tailors its approach to meet each client's unique needs. Dedicated to high standards and personalized recovery plans, the center supports individuals of all genders, offering a nurturing setting for those pursuing healing from addiction and mental health struggles.

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Willapa Behavioral Health and Wellness, located in Montesano, WA, specializes in comprehensive treatment for substance use disorders and provides targeted support for individuals facing co-occurring mental health challenges. The center offers a variety of programs, including intensive outpatient care, outpatient services, and treatment with methadone/buprenorphine or naltrexone, all designed to meet the unique needs of each client. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, this facility adopts a holistic approach to facilitate recovery. Additionally, it features specialized programs for those affected by intimate partner violence, domestic abuse, and individuals within the criminal justice system. Catering to adults and seniors across all genders, this center ensures high-quality care within a nurturing atmosphere.

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Willow House 820 Residential, situated in Westons Mills, NY, provides extended residential treatment for substance use aimed at both adults and young adults. The center employs tailored care methods, including 12-step facilitation, cognitive behavioral therapy, and anger management. It features specialized programs designed for adult men and women, as well as individuals who have faced domestic or intimate partner violence. With an emphasis on gender-specific treatment, Willow House 820 Residential guarantees personalized care for all clients. At this facility, individuals can expect thorough and empathetic support for their addiction recovery in a nurturing residential environment.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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