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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Wooded Glen Recovery Center

At Wooded Glen Recovery Center, located in Henryville, IN, we provide a full spectrum of care for those battling addiction. Our services include medically supervised inpatient detox and specialized treatment for substance use disorders. We also address co-occurring conditions, offering support for adults with mental health challenges and children experiencing emotional disturbances. Our therapeutic approaches encompass 12-step facilitation, anger management, and cognitive behavioral therapy, with personalized plans designed for every client. We offer distinct programs for active military, adult men, and adult women. Wooded Glen Recovery Center is dedicated to providing inclusive and effective treatment for adults and young adults of all genders within a nurturing setting.

Woodhull Medical Center

Situated in Brooklyn, NY, Woodhull Medical Center specializes in rehabilitation services aimed at adults and young adults facing challenges related to substance use and concurrent mental health conditions. The center offers various treatment methods, including outpatient detox and intensive outpatient programs. Emphasizing personalized care, Woodhull Medical Center employs evidence-based techniques such as 12-step facilitation, anger management strategies, and brief interventions to aid in the recovery process. This facility serves both male and female clients, ensuring a customized approach to treatment for each person. Whether for yourself or someone you care about, Woodhull Medical Center is committed to delivering exceptional addiction treatment to support you on your recovery journey.

Woodlake Addiction Recovery Center

Woodlake Addiction Recovery Center located in Ethel, LA, provides an extensive array of services for those battling addiction. The center features hospital-based inpatient detoxification alongside various treatment methodologies, including 12-step programs, anger management techniques, and brief interventions. Catering to a wide audience, it offers specialized programs designed for active duty military members, as well as adult men and women. Woodlake Addiction Recovery Center serves both adults and young adults, delivering gender-specific treatment options. Clients can look forward to receiving top-notch care and individualized treatment strategies aimed at facilitating their recovery process.

Workit Health MI
Ann Arbor, MI

Situated in Ann Arbor, MI, Workit Health MI is dedicated to offering outpatient treatment for substance use aimed at both adults and young adults. The center focuses on addressing co-occurring substance use issues along with significant mental health conditions in adults, and also supports children facing serious emotional challenges. The treatment program features anger management, brief intervention strategies, and cognitive-behavioral therapy. Workit Health MI is equipped to serve clients who have experienced trauma, those living with HIV or AIDS, and individuals dealing with both mental health and substance use disorders. With customized outpatient treatment options including methadone/buprenorphine or naltrexone, the facility provides comprehensive care for all genders, ensuring high-quality support for those in need of assistance.

Wright Path Recovery Center

Wright Path Recovery Center is a leading establishment offering expert care for substance use disorders.

Wright Center for Community Health

Nestled in Jermyn, PA, The Wright Center for Community Health provides complete care for substance use disorders. They address the complex needs of adults experiencing both mental health challenges and addiction, as well as children facing significant emotional difficulties. The center's primary focus is on outpatient services, which include medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their treatment philosophy incorporates proven methods like 12-step support, motivational interviewing, and cognitive behavioral therapy. Specific support is available for active military personnel, teenagers, and adult men, demonstrating a commitment to serving varied populations. This center is dedicated to delivering personalized, high-quality services to adults and older adults, regardless of gender.

Woodridge Hospital
Johnson City, TN

Woodridge Hospital, located in Johnson City, TN, delivers extensive inpatient rehabilitation services aimed at assisting adults and seniors dealing with substance use issues alongside concurrent mental health challenges. This center features customized detox and treatment programs, focusing on the specific requirements of each client. Emphasizing techniques like 12-step guidance, anger management, and brief intervention, Woodridge Hospital promotes a comprehensive recovery experience. It also offers specialized programs for active duty military members, adolescents, and adult males. Patients of all genders benefit from individualized care within a nurturing setting that fosters enduring sobriety and improved mental health.

WTCR Amarillo
Amarillo, TX

At WTCR Amarillo in Amarillo, TX, adults and young adults can access outpatient services for substance use disorder and detoxification. This center excels in 12-step facilitation, anger management, and brief intervention strategies, serving both male and female individuals. They offer specialized support for pregnant and postpartum women, ensuring quality care within a nurturing setting. WTCR Amarillo provides comprehensive treatment options, including detoxification and medication-assisted treatment with methadone, buprenorphine, or naltrexone, tailored to each person's unique recovery journey. Their mission is to guide clients toward sustained sobriety and overall well-being.

Woodlake Addiction Recovery Center

Woodlake Addiction Recovery Center in Abbeville, LA, delivers thorough care for chemical dependency and dual diagnoses for individuals of all ages. Featuring round-the-clock inpatient detoxification and treatment services, the center caters to the unique needs of active military personnel, as well as adult men and women. Employing strategies like 12-step guidance, emotional regulation techniques, and short-term interventions, Woodlake personalizes recovery plans. This facility is dedicated to providing effective support for adults and adolescents of any gender, fostering a nurturing setting to achieve lasting sobriety.

WTCR Dallas
Dallas, TX

WTCR Dallas, situated in Dallas, TX, provides comprehensive outpatient services including substance abuse treatment and detox. They offer tailored programs for expectant and new mothers, serving adults and young adults across the gender spectrum. Their treatment methodologies encompass 12-step facilitation, anger management, and brief intervention. The center specializes in outpatient medication-assisted treatment, utilizing methadone, buprenorphine, or naltrexone. WTCR Dallas is committed to fostering a secure and welcoming space for individuals to begin and sustain their recovery, emphasizing personal healing and development.

Worcester County Health Department

Nestled in Snow Hill, MD, the Worcester County Health Department provides extensive support for individuals facing substance use challenges. The center excels in addressing co-occurring substance use and severe mental health conditions in adults, alongside significant emotional issues in young people. Services are available in multiple formats, including intensive outpatient, outpatient, and outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone). Employing proven therapeutic strategies such as cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the program delivers high-quality care to adults and older adults, regardless of gender. Dedicated programs for active military personnel, teenagers, and adult males distinguish this facility as a premier option for tailored recovery journeys.

Workit Health
Holland, OH

Workit Health, located in Holland, OH, delivers extensive outpatient treatment for substance use issues targeting both adults and young adults. This center is adept at addressing co-occurring substance use problems alongside significant mental health challenges and emotional issues. Emphasizing personalized treatment, their programs incorporate anger management, cognitive behavioral therapy, and short-term interventions. Workit Health also extends specialized assistance to those who have faced trauma, individuals living with HIV or AIDS, as well as clients dealing with simultaneous mental health and substance use disorders. The facility provides outpatient options including methadone, buprenorphine, or naltrexone treatments, serving both male and female clients in a compassionate setting.

Worcester County Health Department

In Ocean City, MD, the Worcester County Health Department delivers a full spectrum of substance use therapy for adults facing concurrent mental health challenges. They offer robust intensive outpatient services, standard outpatient care, and targeted treatments using methadone, buprenorphine, or naltrexone. Employing proven methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, the center serves active duty military, young people, and adult men. Their offerings are designed for adults and older adults across all gender identities, emphasizing personalized treatment strategies and programs designed for particular groups.

Worcester County Health Department

Situated in Pocomoke City, MD, the Worcester County Health Department delivers extensive rehabilitation services for adults facing substance use issues alongside serious mental health disorders. The center offers both intensive outpatient and standard outpatient programs, featuring targeted treatments such as methadone, buprenorphine, or naltrexone. Emphasizing techniques like anger management, cognitive behavioral therapy, and the Matrix Model, this center accommodates active military members, teenagers, and adult males. Serving individuals of all genders, including seniors, Worcester County Health Department is dedicated to providing personalized care, making it an essential asset for those in need of effective addiction recovery services.

Workit Health (MI) PLLC

Workit Health (MI) PLLC, located in Austin, TX, delivers outpatient care for individuals struggling with substance misuse. This program is specifically designed for adults and young adults who are also managing significant mental health conditions or emotional challenges. The center features tailored services for those with a history of trauma, individuals living with HIV or AIDS, and those facing combined mental health and substance use issues. Treatment methodologies encompass areas like anger management, motivational interviewing, and cognitive restructuring. Offering medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, Workit Health (MI) PLLC is dedicated to providing effective support for all clients.

WPIC Narcotic Addiction Treatment Prog

Situated in Pittsburgh, PA, WPIC Narcotic Addiction Treatment Prog delivers a wide range of addiction recovery services for both adults and younger individuals. This center specializes in inpatient detox and treatment, focusing on patients dealing with concurrent substance abuse and mental health issues. The program implements proven methods, including cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. With dedicated programs for adolescents and adult men and women, WPIC Narcotic Addiction Treatment Prog addresses the unique needs of various groups. Patients can anticipate personalized care designed to meet their individual challenges, promoting effective and empathetic support throughout their recovery process.

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The Women's Institute for Family Health, situated in Philadelphia, PA, delivers a wide range of substance abuse treatment options. This center specializes in intensive outpatient care, standard outpatient services, and methadone/buprenorphine or naltrexone therapy. Emphasizing 12-step education, anger management techniques, and brief interventions, the facility supports both adult males and females, including those who have faced domestic or intimate partner violence. Catering to both adults and older adults, this center prioritizes personalized care and guidance for individuals on their journey to recovery. Discover exceptional treatment at this esteemed rehabilitation facility.

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Wood County Human Services Department, located in Wisconsin Rapids, WI, provides outpatient treatment for substance use, in addition to specialized services for adults facing dual challenges of substance use and severe mental health issues, as well as emotional problems in children. Emphasizing techniques such as anger management, cognitive behavioral therapy, and the Matrix Model, this center offers various options including outpatient day programs, partial hospitalization, and medication-assisted therapies with methadone, buprenorphine, or naltrexone. Customized programs are designed for adolescents, as well as adult men and women, ensuring support for seniors and individuals of all genders. Experience comprehensive care and personalized treatment at this dedicated rehabilitation facility.

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In Berlin, MD, the Worcester County Health Department provides extensive services for individuals facing substance use disorders alongside mental health concerns. They offer specialized care for adults with co-occurring serious mental health issues and for children experiencing serious emotional disturbances. The center features intensive outpatient and outpatient treatment options, including medication-assisted therapies such as methadone/buprenorphine and naltrexone. Employing proven therapeutic methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, their programs are accessible to active duty military personnel, teenagers, adult men, and older adults. Tailored programs for both men and women are available, guaranteeing personalized support throughout the recovery journey for addiction and mental health challenges.

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Woodbury Heights, NJ

Situated in Woodbury Heights, NJ, "Wounded Healer" delivers extensive treatment for substance use disorders while also addressing co-occurring mental health challenges in adults and emotional issues in children. The center offers a range of services including intensive outpatient programs, standard outpatient care, and treatments with methadone, buprenorphine, or naltrexone. Emphasizing anger management, brief interventions, and cognitive behavioral therapy, the facility supports both men and women adults, as well as those affected by intimate partner or domestic violence. "Wounded Healer" is dedicated to providing effective care with customized programs that promote a holistic approach to recovery for adults and adolescents of all genders.

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Abilene, TX

WTCR Abilene Inc in Abilene, TX provides a full spectrum of care for those in recovery. Their programs include outpatient detox and treatment for substance use disorders, utilizing medications such as methadone, buprenorphine, or naltrexone. The center's expertise lies in serving adults and young adults, with particular attention to pregnant and postpartum women. Employing proven methods like 12-step facilitation, anger management, and brief intervention, they deliver effective care to all genders. For specialized assistance in a supportive setting, explore the varied therapeutic paths at WTCR Abilene Inc.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)