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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Workit Health MI
Ann Arbor, MI

Situated in Ann Arbor, MI, Workit Health MI is dedicated to offering outpatient treatment for substance use aimed at both adults and young adults. The center focuses on addressing co-occurring substance use issues along with significant mental health conditions in adults, and also supports children facing serious emotional challenges. The treatment program features anger management, brief intervention strategies, and cognitive-behavioral therapy. Workit Health MI is equipped to serve clients who have experienced trauma, those living with HIV or AIDS, and individuals dealing with both mental health and substance use disorders. With customized outpatient treatment options including methadone/buprenorphine or naltrexone, the facility provides comprehensive care for all genders, ensuring high-quality support for those in need of assistance.

Wright Path Recovery Center

Wright Path Recovery Center is a leading establishment offering expert care for substance use disorders.

Yana House
Chicago, IL

Yana House, situated in Chicago, IL, provides extended stay residential rehabilitation for men struggling with addiction. This establishment is equipped to address the unique needs of individuals dealing with both chronic pain and substance abuse, as well as those with a history of trauma. Emphasizing principles of the 12-step program, techniques for managing anger, and brief intervention strategies, Yana House serves a diverse age range, including adults, older adults, and young adults, who are looking for a structured and encouraging setting for their healing journey. Additionally, the center features transitional living arrangements. Clients can anticipate a high standard of treatment and customized recovery plans aimed at fostering sustained abstinence and comprehensive wellness.

Your Recovery Counseling

Your Recovery Counseling, situated in Beachwood, OH, delivers targeted substance abuse recovery services for adults and adolescents facing concurrent serious mental health conditions or emotional challenges. The facility offers robust intensive outpatient, outpatient, and day treatment options, incorporating techniques such as anger management, cognitive behavioral therapy, and brief intervention strategies. Recognizing the unique needs of active duty military members, adult men, and women, the center prioritizes personalized treatment plans. Your Recovery Counseling is dedicated to providing exceptional, all-encompassing rehabilitation care to assist individuals in achieving lasting recovery.

Yakima Neighborhood Health Services

Yakima Neighborhood Health Services, located in Yakima, WA, delivers comprehensive outpatient services for substance use disorders. Their offerings include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside traditional outpatient counseling. The center also incorporates crucial therapeutic modalities such as anger management, brief intervention, and cognitive behavioral therapy. Care is specifically designed for active duty military, teenagers, adult males, and adults and seniors of any gender. Yakima Neighborhood Health Services is dedicated to crafting personalized treatment strategies and ensuring high standards of care, making it a reliable choice for individuals in the Yakima region pursuing robust addiction recovery solutions.

Wright Center for Community Health

Nestled in Jermyn, PA, The Wright Center for Community Health provides complete care for substance use disorders. They address the complex needs of adults experiencing both mental health challenges and addiction, as well as children facing significant emotional difficulties. The center's primary focus is on outpatient services, which include medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their treatment philosophy incorporates proven methods like 12-step support, motivational interviewing, and cognitive behavioral therapy. Specific support is available for active military personnel, teenagers, and adult men, demonstrating a commitment to serving varied populations. This center is dedicated to delivering personalized, high-quality services to adults and older adults, regardless of gender.

Yamhill CO Mental Health Program

Yamhill CO Mental Health Program, located in McMinnville, OR, provides a wide variety of treatment options for both substance use issues and concurrent mental health disorders, targeting adults and young adults. Their offerings include intensive outpatient services, long-term residential programs, and standard outpatient care. This center is renowned for its expertise in anger management, cognitive behavioral therapy, and the Matrix Model methodology. They have tailored programs that specifically address the needs of adult men, women, and those dealing with dual diagnoses of mental health and substance use disorders. Committed to delivering high-quality care, the facility ensures personalized treatment plans for every client who seeks assistance.

Workit Health
Holland, OH

Workit Health, located in Holland, OH, delivers extensive outpatient treatment for substance use issues targeting both adults and young adults. This center is adept at addressing co-occurring substance use problems alongside significant mental health challenges and emotional issues. Emphasizing personalized treatment, their programs incorporate anger management, cognitive behavioral therapy, and short-term interventions. Workit Health also extends specialized assistance to those who have faced trauma, individuals living with HIV or AIDS, as well as clients dealing with simultaneous mental health and substance use disorders. The facility provides outpatient options including methadone, buprenorphine, or naltrexone treatments, serving both male and female clients in a compassionate setting.

Yellow Wood Recovery
Rancho Cordova, CA

Yellow Wood Recovery, situated in Rancho Cordova, CA, provides complete addiction recovery solutions for adults and adolescents. This establishment excels in extended residential stays, detox services within a residential setting, and round-the-clock residential support. By integrating anger management techniques, brief intervention strategies, and cognitive behavioral therapy, the center delivers customized care for individuals facing both substance use disorders and significant mental health challenges. Yellow Wood Recovery serves adult men and women, along with individuals with histories of trauma. Its gender-specific approaches guarantee personalized attention for both male and female patients, prioritizing high standards and successful rehabilitation outcomes.

Your Neighborhood Health Clinic

Your Local Rehab Clinic in Phoenix, AZ, delivers a wide range of outpatient services for detoxification and treatment of substance use disorders. The facility offers various programs, including outpatient day treatment, partial hospitalization, and outpatient detoxification. Emphasizing relapse prevention and counseling for substance use disorders, the center also provides telemedicine and telehealth options for easy access. Specialized programs are designed for active duty military members, adult men, and adult women. Catering to adults and young adults of all genders, this clinic ensures comprehensive care and support for individuals pursuing successful addiction recovery.

Your Path LLC
Saint Paul, MN

Your Path LLC located in Saint Paul, MN, provides customized outpatient treatment options for addressing substance use disorders, focusing on the unique needs of each client. The center offers outpatient services that include methadone/buprenorphine or naltrexone treatments, standard outpatient therapy, and methodologies such as anger management, brief interventions, and cognitive behavioral therapy. Your Path LLC also features specialized programs for active duty military personnel, adult men, and adult women, accommodating a wide variety of individuals. This facility serves both adults and young adults of all genders, committed to delivering high-quality support and care to those aiming to conquer addiction and reclaim their lives.

Workit Health (MI) PLLC

Workit Health (MI) PLLC, located in Austin, TX, delivers outpatient care for individuals struggling with substance misuse. This program is specifically designed for adults and young adults who are also managing significant mental health conditions or emotional challenges. The center features tailored services for those with a history of trauma, individuals living with HIV or AIDS, and those facing combined mental health and substance use issues. Treatment methodologies encompass areas like anger management, motivational interviewing, and cognitive restructuring. Offering medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, Workit Health (MI) PLLC is dedicated to providing effective support for all clients.

YES Community Counseling Center

The YES Community Counseling Center, situated in Massapequa, NY, delivers focused outpatient services for adults dealing with substance abuse and concurrent mental health challenges, as well as support for children facing emotional difficulties. Emphasizing brief interventions, cognitive behavioral techniques, and motivational interviewing, the center tailors its approaches to meet the needs of both adults and seniors. Additionally, it features specialized programs targeted at adolescents and distinct groups such as adult men and women, ensuring personalized assistance. The center also offers outpatient treatment options including methadone, buprenorphine, and naltrexone, all within a supportive setting. With a strong dedication to delivering quality care, this center stands out as a reliable option for individuals pursuing effective rehabilitation solutions.

YMCA Family Services
Holtsville, NY

YMCA Family Services located in Holtsville, NY, delivers an extensive program for treating substance use issues. This center offers outpatient care, featuring methadone, buprenorphine, or naltrexone treatments alongside standard outpatient services. It emphasizes anger management, brief interventions, and cognitive behavioral therapy, specifically designed for adolescents and adult females. Catering to a diverse clientele, including both adults and youth, the program welcomes clients of all genders. YMCA Family Services is recognized for its personalized methods, guaranteeing exceptional care and assistance during the recovery process.

YWCA of Fort Dodge
Fort Dodge, IA

The YWCA of Fort Dodge, situated in Fort Dodge, IA, delivers extensive support for individuals navigating substance use challenges. Their offerings encompass intensive outpatient care, extended residential stays, and flexible outpatient programs, specifically designed for adult women and those impacted by trauma. Employing strategies such as 12-step facilitation, anger management, and brief intervention, the YWCA of Fort Dodge excels in addressing co-occurring mental health and substance use conditions. Serving adults and young adults across genders, the center is committed to delivering high-quality, nurturing care, positioning it as a premier destination for individuals pursuing meaningful rehabilitation and lasting recovery.

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In Berlin, MD, the Worcester County Health Department provides extensive services for individuals facing substance use disorders alongside mental health concerns. They offer specialized care for adults with co-occurring serious mental health issues and for children experiencing serious emotional disturbances. The center features intensive outpatient and outpatient treatment options, including medication-assisted therapies such as methadone/buprenorphine and naltrexone. Employing proven therapeutic methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, their programs are accessible to active duty military personnel, teenagers, adult men, and older adults. Tailored programs for both men and women are available, guaranteeing personalized support throughout the recovery journey for addiction and mental health challenges.

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Woodbury Heights, NJ

Situated in Woodbury Heights, NJ, "Wounded Healer" delivers extensive treatment for substance use disorders while also addressing co-occurring mental health challenges in adults and emotional issues in children. The center offers a range of services including intensive outpatient programs, standard outpatient care, and treatments with methadone, buprenorphine, or naltrexone. Emphasizing anger management, brief interventions, and cognitive behavioral therapy, the facility supports both men and women adults, as well as those affected by intimate partner or domestic violence. "Wounded Healer" is dedicated to providing effective care with customized programs that promote a holistic approach to recovery for adults and adolescents of all genders.

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Wyoming Recovery, situated in Casper, WY, is a facility dedicated to providing extensive rehabilitation programs. They offer detox services, address substance abuse, and deliver tailored support for individuals dealing with co-occurring mental health conditions and substance use disorders, or significant emotional challenges in minors. Their flexible treatment approaches include intensive outpatient, extended residential stays, and standard outpatient care, serving adult men and women, and those affected by domestic or intimate partner violence. Employing strategies like 12-step facilitation, anger management, and brief intervention, Wyoming Recovery extends effective addiction treatment to adults and young adults across all genders.

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McMinnville, OR

Nestled in McMinnville, OR, Yamhill County delivers a full spectrum of care for substance use challenges. They provide transitional living and specialized treatment for co-occurring mental health and addiction issues in both younger and adult individuals. This center employs proven methods like 12-step integration, brief counseling, and cognitive behavioral therapy within its intensive outpatient, day treatment, and standard outpatient programs. Dedicated tracks are available for men, women, and individuals healing from trauma. Yamhill County is committed to offering personalized, effective recovery for adults and young adults, with separate, gender-affirming treatment for males and females. Discover exceptional support designed around your unique journey.

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McMinnville, OR

Yamhill County, situated in McMinnville, OR, delivers extensive substance use rehabilitation services designed for adults, seniors, and young adults. This center is adept at addressing dual diagnoses involving substance abuse and significant mental health challenges in adults, in addition to severe emotional issues in children. Yamhill County implements intensive outpatient, outpatient, and standard outpatient treatment modalities, employing evidence-based practices like cognitive behavioral therapy, the Matrix Model, and motivational interviewing techniques. The facility also features specialized programs for adolescents and those in criminal justice settings, accommodating a wide variety of individuals pursuing recovery. With customized support for both men and women, Yamhill County guarantees high-caliber treatment for every client.

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YES Community Counseling Center, situated in Levittown, NY, provides essential outpatient treatment for substance use, as well as specialized services for those facing co-occurring disorders and significant mental health challenges in adults, along with emotional issues in children. The center offers outpatient options including methadone, buprenorphine, and naltrexone therapy, in addition to standard outpatient programs. With a focus on evidence-based methodologies such as brief interventions, cognitive behavioral therapy, and motivational interviewing, this facility serves adolescents, as well as adult men and women. Catering to adults and seniors of all genders, YES Community Counseling Center is recognized for its personalized treatment plans and dedication to delivering high-quality care for those in need of extensive rehabilitation services.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)