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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 7,994 treatment centers offering naltrexone (vivitrol) across the United States.

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South Charlotte VA Healthcare Center

The South Charlotte VA Healthcare Center in Charlotte, NC, provides dedicated substance use treatment for adults and young adults facing co-occurring serious mental health conditions. Their offerings encompass intensive outpatient, standard outpatient, and medication-assisted treatment options (methadone/buprenorphine or naltrexone). Employing therapeutic modalities such as 12-step facilitation, anger management, and brief interventions, the center is equipped to support individuals with trauma histories and veterans. The facility is committed to delivering high-quality, personalized care for both male and female patients pursuing thorough recovery plans.

South Coast Behavioral Health
Huntington Beach, CA

Situated in Huntington Beach, CA, South Coast Behavioral Health delivers a wide range of treatment options for addiction, catering to both adults and young adults. The facility offers services including residential detox, around-the-clock care, and short-term living programs for individuals facing substance use challenges alongside mental health disorders. Acknowledging the unique experiences of its clients, the center has tailored programs for men, women, and those who have experienced domestic or intimate partner violence. By employing methods like 12-step guidance, anger management, and concise intervention strategies, South Coast Behavioral Health focuses on individualized support for every person. Committed to high standards of evidence-based care, the center aims to empower clients on their journey to lasting recovery.

South Coast Behavioral Health
Huntington Beach, CA

Situated in Huntington Beach, CA, South Coast Behavioral Health presents an extensive array of recovery services tailored for individuals in need. This center focuses on detoxification and substance use therapy, catering to clients dealing with both substance use disorders and significant mental health challenges. It offers various programs, including residential detox, round-the-clock care, and short-term residential options. Utilizing methods such as 12-step facilitation, anger management, and brief interventions, the center is designed for adult men and women, including those who have faced intimate partner violence. South Coast Behavioral Health is dedicated to assisting both adults and young adults with specialized care for each gender.

South Coast Behavioral Health

South Coast Behavioral Health, situated in Irvine, California, presents an extensive array of treatment options designed for adults and young adults facing challenges related to substance use and co-occurring mental health issues. The center features residential detox, short-term residential stays, and around-the-clock residential support, emphasizing 12-step facilitation, anger management strategies, and brief intervention techniques. Specialized programs are designed for adult men, adult women, and individuals who have encountered intimate partner or domestic violence. With a committed team of experts, this facility delivers high-quality, personalized care, fostering a nurturing atmosphere conducive to healing and recovery.

South Coast Behavioral Health

South Coast Behavioral Health, situated in Costa Mesa, CA, delivers extensive addiction recovery programs for adults and young adults. They offer inpatient detox, round-the-clock inpatient care, and brief inpatient stays. Specializing in substance abuse, co-occurring psychiatric conditions, and emotional challenges, South Coast Behavioral Health employs proven methods like 12-step support, anger resolution techniques, and concise interventions to aid in the healing process. They provide distinct tracks for men, women, and survivors of domestic abuse, guaranteeing personalized support. The commitment at South Coast Behavioral Health is to high-quality care in a nurturing setting conducive to wellness and sobriety.

South Coast Behavioral Health

South Coast Behavioral Health, situated in Irvine, CA, delivers extensive substance abuse treatment for adults and young adults. The center provides inpatient detox, round-the-clock inpatient supervision, and brief inpatient stays, all customized to each person's unique requirements. Offering distinct programs for adult men, adult women, and individuals affected by domestic abuse, South Coast Behavioral Health fosters a secure and nurturing space for healing. Employing methods like 12-step integration, emotional regulation training, and motivational enhancement, the facility concentrates on treating concurrent substance abuse and mental health challenges. Committed to delivering excellent care, this institution serves as a symbol of optimism for those aiming to conquer addiction and reclaim their lives.

South Coast Counseling Inc

Based in Costa Mesa, CA, South Coast Counseling Inc delivers a wide array of treatment services aimed at helping individuals overcome substance use challenges and related mental health conditions. The center caters to both adults and young adults, offering various programs such as intensive outpatient care, long-term residential treatment, and traditional outpatient services. The facility employs methods including 12-step support, anger management strategies, and short intervention practices. What sets South Coast Counseling Inc apart is its dedicated focus on those with dual diagnoses, allowing for personalized treatment plans. Committed to providing quality assistance, the center fosters a nurturing atmosphere for all clients, regardless of gender, as they work towards sustainable recovery.

South Shore Recovery Home

Situated in Quincy, MA, South Shore Recovery Home provides extensive substance abuse rehabilitation and transitional living arrangements for adult males in a nurturing and secure setting. The facility features inpatient hospital treatment, round-the-clock hospital care, and long-term residential options. Employing evidence-based methods such as 12-step programs, anger management, and cognitive behavioral therapy, the center customizes its treatments to fit the unique requirements of each individual. There are specialized services for active military personnel, adult men, and those who have encountered intimate partner violence. South Shore Recovery Home is committed to offering high-quality support tailored to adult and senior male clients on their journey toward recovery.

South Community Inc

Situated in Dayton, OH, South Community Inc delivers extensive outpatient recovery services designed for individuals struggling with addiction and co-occurring psychological conditions. Employing proven methods such as cognitive behavioral therapy and motivational incentives, the facility offers dedicated support for young people and adults experiencing significant emotional challenges. South Community Inc addresses issues like anger management and employs positive reinforcement strategies, serving teenagers, adult males, and adult females. Their personalized outpatient treatment plans, which may include methadone, buprenorphine, or naltrexone, are crafted for adults and older adults across all gender identities, promising superior and impactful recovery solutions.

South Central Mental Health

South Central Mental Health Counseling Center Inc in Andover, Kansas, offers regular outpatient care, day treatment or partial hospitalization, and buprenorphine and naltrexone services. A young adult program is available, and children through seniors are admitted. Medicare, Medicaid, TRICARE, SAMHSA block grants, payment assistance, and state-financed plans help cover treatment costs.

South Central Montana Regional MHC

South Central Montana Regional MHC, located in Billings, MT, provides an extensive array of services aimed at addressing substance abuse and concurrent mental health issues. This facility features tailored programs designed for adult men and women, as well as for children and teenagers. The center offers both intensive outpatient and outpatient treatment options, including therapies using methadone and buprenorphine. By incorporating methods such as 12-step programs, anger management, and brief intervention strategies, South Central Montana Regional MHC guarantees personalized and effective care. Focused on delivering high-quality treatment, the center supports both male and female clients in their journey toward recovery from addiction and mental health struggles.

South Coast Behavioral Health

Residential detoxification and short- and long-term residential treatment are available in Oklahoma City, Oklahoma at South Coast Behavioral Health, using buprenorphine and naltrexone. Programs serve adult men and women, veterans, and clients with co-occurring disorders. Medicaid, tribal funds, and private insurance are accepted, with Spanish and sign language services.

South Portland Comprehensive Treatment

This South Portland, Maine, outpatient program combines methadone, buprenorphine, and naltrexone with treatment for adults with opioid use disorder. Programs serve veterans, military families, pregnant women, and clients with co-occurring conditions. Medicare, Medicaid, and SAMHSA block grants are accepted.

South Richmond Hill Recovery

South Richmond Hill Recovery in Ozone Park, New York runs regular and intensive outpatient substance use programs for adults, including pregnant and postpartum women, veterans, and clients with HIV or AIDS. Buprenorphine and naltrexone are used. Medicare, Medicaid, TRICARE, and sliding fees are accepted, with services in Spanish, Chinese, Arabic, Creole, and Hindi.

South Richmond Hill Recovery LLC

Adults in Brooklyn, New York can attend regular or intensive outpatient treatment at South Richmond Hill Recovery's Outpatient Clinic 2, with programs for pregnant and postpartum women, veterans, and clients with HIV or AIDS. Buprenorphine and naltrexone are used. Medicare, Medicaid, and sliding fees are accepted, with services in Spanish, Chinese, Arabic, Creole, and Hindi.

South Shore Recovery Center

South Shore Recovery Center in Plymouth, Massachusetts, spans partial hospitalization, intensive outpatient, and regular outpatient care, with buprenorphine and naltrexone used in treatment for substance use and co-occurring serious mental illness. Adults of all ages are served. Medicaid, TRICARE, tribal funds, private insurance, and state-financed plans are accepted. Sign language services available.

South Oaks Hospital
Amityville, NY

Situated in Amityville, NY, South Oaks Hospital delivers extensive detox and substance use treatment services for adults and young adults. Emphasizing personalized care, this establishment offers inpatient detox programs along with 24/7 medical support. The center employs various methods such as 12-step facilitation, anger management, and brief interventions to tackle addiction issues. South Oaks Hospital is notable for its customized programs catering to both men and women, fostering a supportive and welcoming atmosphere. If you or someone you know is in need of compassionate and effective treatment for addiction, this facility is committed to offering exceptional care to aid in the recovery process.

South Oaks Hospital
Amityville, NY

Situated in Amityville, NY, South Oaks Hospital provides targeted treatment for substance use disorders in an inpatient hospital environment, catering to adults and young adults. Emphasizing personalized care, this facility incorporates various approaches, including 12-step facilitation, anger management, and brief intervention strategies. South Oaks Hospital customizes its treatment plans to address the specific needs of each individual client. The center creates a welcoming and supportive space for both male and female patients, fostering an inclusive atmosphere for recovery. For those seeking thorough and tailored addiction treatment, South Oaks Hospital is committed to delivering exceptional care to aid in the path to sobriety.

South Strand Internists
Myrtle Beach, SC

Situated in Myrtle Beach, SC, South Strand Internists specializes in outpatient treatment for substance use disorders, focusing on adults with dual diagnoses of substance use and severe mental health problems, as well as emotional issues in children. The center offers outpatient services with medications such as methadone/buprenorphine or naltrexone, employing a variety of methods including 12-step programs, brief interventions, and motivational strategies. Programs specifically designed for active duty military personnel, as well as separate options for adult men and women, are accessible. This facility provides comprehensive care for adults and seniors of all backgrounds, ensuring a professional and supportive atmosphere for those in need of addiction recovery services.

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South County Youth Services, situated in Alexandria, VA, provides outpatient treatment for substance use disorders for both adults and children with accompanying mental health issues. The center focuses on short-term interventions, relapse prevention strategies, and counseling for those struggling with substance use. Catering primarily to adolescents and young adults, as well as individuals facing dual diagnoses, the facility offers customized care for both females and males of various ages. By prioritizing personalized treatment plans and extensive support, this center strives to deliver exceptional care for individuals aiming to overcome substance use challenges and related mental health concerns.

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Situated in Yankton, SD, the South Dakota Human Services Center delivers extensive treatment for substance use disorders in adults and young adults who also face significant mental health challenges or emotional issues. This center features inpatient hospital services with round-the-clock care, employing research-backed methods such as 12-step facilitation, cognitive behavioral therapy, and contingency management. Emphasizing personalized treatment plans, the center serves both male and female clients who are in search of compassionate and effective care. For those in need of specialized programs and customized recovery strategies, the South Dakota Human Services Center is committed to supporting you on the journey to sustained sobriety.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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