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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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BrightView Health
Plymouth, MA

BrightView Health, located in Plymouth, MA, specializes in providing a wide range of addiction recovery services tailored for both adults and young adults. The center facilitates detoxification as well as comprehensive substance use treatment options, including intensive outpatient, outpatient, and day programs. Employing proven methods such as cognitive behavioral therapy and community reinforcement plus vouchers, this facility serves men and women, including pregnant and postpartum individuals, across all gender identities. Committed to delivering high-quality care and personalized treatment strategies, BrightView Health stands out as an excellent option for those pursuing compassionate and effective rehabilitation in the Plymouth region.

BrightView Health
Springfield, OH

Situated in Springfield, OH, BrightView Health delivers an extensive range of services aimed at treating addiction in both adults and young adults. The facility specializes in detoxification, treatment for substance use, and tailored support for individuals facing both substance use disorders and significant mental health challenges. BrightView Health features intensive outpatient services, various outpatient programs, and outpatient detoxification options. Their methodology incorporates strategies such as anger management, brief intervention, and cognitive behavioral therapy. Notably, this center is recognized for its dedicated programs catering to the LGBTQ community and support for women during pregnancy and postpartum. With customized interventions available for men and women, BrightView Health prioritizes exceptional care to assist individuals throughout their recovery process.

BrightView Health

BrightView Health, located in Newark, OH, specializes in extensive addiction recovery services for both adults and younger populations. The center offers detox support, behavioral therapy, and various therapeutic approaches like anger management, brief interventions, and cognitive behavioral techniques. Emphasizing personalized care, BrightView Health customizes treatment plans to align with the specific requirements of each individual. The facility provides options such as intensive outpatient care, outpatient services, and partial hospitalization, accommodating clients of all genders. Individuals can anticipate receiving exceptional support and assistance on their path to recovery at BrightView Health.

BrightView Health

BrightView Health, situated in Marion, OH, delivers extensive addiction recovery support for adults and younger individuals. The facility facilitates detox and addresses substance use challenges via intensive outpatient, standard outpatient, and outpatient detox options. Employing methodologies like anger management, brief intervention, and cognitive behavioral therapy, this center delivers tailored support to meet each person's unique requirements. A distinguishing feature of BrightView Health is its dedicated LGBTQ program, promoting an inclusive and supportive atmosphere for everyone seeking help. Committed to high standards of care, this center welcomes both male and female individuals, fostering a secure and encouraging setting for their healing journey.

BrightView Health
Georgetown, OH

BrightView Health in Georgetown, OH, provides extensive addiction recovery care for individuals of all ages. They offer detox and drug treatment through various levels of care, including intensive outpatient, standard outpatient, and outpatient detox. Specializing in techniques like anger management, brief intervention, and cognitive behavioral therapy, BrightView Health also has dedicated resources for the LGBTQ community. Their approach emphasizes personalized treatment plans for men and women in a nurturing setting, ensuring quality rehabilitation.

BrightView Health

BrightView Health, situated in Piqua, OH, delivers a full spectrum of care for addiction. They offer detoxification and treatment for substance use disorders through intensive outpatient, standard outpatient, and outpatient detoxification options. Employing methods like anger management, brief intervention, and cognitive behavioral therapy, the center serves adults and young adults of all gender identities, including specific support for the LGBTQ+ community. BrightView Health is committed to providing personalized attention and scientifically proven treatments to guide individuals toward lasting recovery with empathy and skill.

BrightView Health
Youngstown, OH

BrightView Health, located in Youngstown, OH, delivers a wide range of addiction recovery services aimed at both adults and young adults. The facility facilitates detoxification along with various substance use treatment options, including intensive outpatient care, outpatient services, and outpatient detox programs. By incorporating techniques such as anger management, brief interventions, and cognitive behavioral therapy, the center customizes its treatments to meet the specific requirements of each individual. BrightView Health also emphasizes programs designed for the LGBTQ community, supporting lesbian, gay, bisexual, transgender, and queer/questioning individuals. Committed to providing exemplary care, this center serves both male and female clients on their journey to overcoming addiction.

BrightView Health

BrightView Health in Lima, OH, provides complete addiction recovery options, featuring detox and therapy for substance use. They serve adults and younger adults, with dedicated support for LGBTQ individuals and women who are pregnant or have recently given birth. Their therapeutic methods include anger management, short-term intervention, and cognitive behavioral therapy. The facility offers intensive outpatient services, standard outpatient care, and outpatient detox, fitting different requirements and desires. Prioritizing excellent care and customized recovery strategies, BrightView Health guides individuals toward sustained sobriety.

BrightView Health

Situated in Newark, OH, BrightView Health specializes in a wide range of addiction treatment options for both adults and young adults. Emphasizing detoxification and addressing substance use issues, this center offers intensive outpatient treatment, outpatient programs, and detoxification services. BrightView Health employs various methods, including anger management strategies, brief interventions, and cognitive behavioral therapy, ensuring that those in need receive specialized support, including services designed for LGBTQ individuals and pregnant or postpartum women. With programs adjusted for both male and female clients, this center is dedicated to delivering personalized, high-quality care to aid individuals in their recovery process.

BrightView Health

BrightView Health in Kent, OH, stands as a premier facility for individuals seeking recovery from addiction. This center specializes in comprehensive detoxification and ongoing substance use disorder care. They offer a spectrum of treatment modalities, including intensive outpatient, standard outpatient, and day treatment programs. Their therapeutic interventions encompass strategies like anger management, brief intervention techniques, and cognitive behavioral therapy. A key feature of BrightView Health is its commitment to a personalized treatment experience, welcoming adults and young adults regardless of gender. Their dedication to delivering high-caliber care and tailoring treatment plans ensures a focused path toward overcoming addiction and fostering lasting sobriety.

BrightView Health
Georgetown, KY

BrightView Health, located in Georgetown, KY, specializes in detox and treatment services for both adults and young adults dealing with substance use disorders. The facility offers a range of programs, including intensive outpatient, outpatient, and day treatment services, utilizing methods such as cognitive behavioral therapy, brief interventions, and anger management. With an emphasis on personalized care, BrightView Health accommodates both men and women in need of thorough addiction recovery solutions. Its dedication to high-quality care and customized treatment plans positions it as an essential resource for individuals seeking to begin their recovery journey.

BrightView Health
Lancaster, OH

Situated in Lancaster, Ohio, BrightView Health delivers thorough addiction recovery programs for individuals of all ages. Their services encompass detox and comprehensive care via intensive outpatient, standard outpatient, and day treatment modalities. BrightView Health is distinguished by its personalized approach, employing methods like anger management, brief intervention, and cognitive behavioral therapy. Committed to crafting unique treatment pathways, this institution welcomes both male and female participants, fostering a welcoming atmosphere. For those in search of customized and successful addiction treatment, BrightView Health in Lancaster is devoted to offering excellent support throughout the recovery process.

BrightView Health
Columbus, OH

BrightView Health, located in Columbus, OH, provides a wide array of addiction recovery services designed for both adults and young adults. This facility features intensive outpatient programs, outpatient detox services, and various outpatient options. They employ techniques including anger management, brief intervention, and cognitive behavioral therapy, customizing the treatment to meet each person's unique requirements. BrightView Health is distinguished by its dedicated programs for the LGBTQ community and for pregnant or postpartum women. Committed to delivering high-quality care, the center supports clients of all genders, fostering an inclusive and nurturing atmosphere for those on their journey to overcome substance use challenges.

BrightView Health

BrightView Health, located in Batavia, OH, delivers extensive addiction treatment options tailored for both adults and young adults. The center specializes in detox services, recovery from substance misuse, and dedicated support for those facing simultaneous substance use and significant mental health issues. With intensive outpatient and regular outpatient programs available, BrightView Health employs proven methods, including cognitive behavioral therapy and anger management strategies. A distinguishing feature of this facility is its programs designed specifically for the LGBTQ community and for pregnant or postpartum women, highlighting its commitment to inclusive and personalized care. Catering to clients of all genders, BrightView Health emphasizes high-quality treatment to aid individuals on their journey to recovery.

BrightView Health
Henderson, KY

BrightView Health, situated in Henderson, KY, delivers a full spectrum of addiction recovery solutions for adults and young adults. The facility excels in providing detox and substance use treatment through proven methods like cognitive behavioral therapy, community reinforcement with vouchers, and contingency management. What sets BrightView Health apart is its personalized approach, crafting programs to address the specific requirements of every individual. Offering services such as intensive outpatient, outpatient, and day treatment (also known as partial hospitalization), this center provides high-quality support for both men and women on their journey to recovery.

BrightView Health

BrightView Health in Dover, OH, is dedicated to providing thorough addiction recovery support within a comfortable setting. The facility delivers various levels of care including intensive outpatient programs, general outpatient services, and medication-assisted treatment options using methadone, buprenorphine, or naltrexone, catering to adults and young adults. Employing scientifically validated methods such as cognitive behavioral therapy, strategies for preventing relapse, and expert counseling for substance use disorders, BrightView Health customizes its offerings to meet the specific needs of each person. The center's distinctive emphasis on a personalized treatment plan guarantees that both male and female individuals receive care uniquely suited to them. For those looking for effective addiction care with a personal connection, BrightView Health stands as a reliable ally in the path to regaining sobriety.

BrightView Health
Columbus, OH

Situated in Columbus, OH, BrightView Health delivers an extensive array of services for those facing addiction. This center focuses on detoxification and treatment for both adults and young adults grappling with substance use disorders. It features intensive outpatient programs, general outpatient care, and outpatient detox services. Clients have access to various therapeutic methods, including anger management, brief interventions, and cognitive behavioral therapy. BrightView Health is particularly noted for its tailored programs designed for LGBTQ individuals and pregnant or postpartum women. Committed to providing high-quality care, the center serves both men and women, fostering a welcoming and supportive atmosphere for everyone on their path to recovery.

BrightView Health
Cincinnati, OH

Situated in Cincinnati, OH, BrightView Health serves as a holistic rehabilitation center focused on detoxification and substance abuse recovery programs. The facility offers a range of services, including intensive outpatient therapy, standard outpatient care, and outpatient detox support. BrightView Health is known for its expertise in areas such as anger management, brief intervention strategies, and cognitive behavioral therapy. It also features specialized programs designed for the LGBTQ community and for women during pregnancy and the postpartum period. The center caters to adults and young adults of all gender identities, emphasizing personalized treatment and evidence-based methodologies to achieve successful recovery results. BrightView Health is recognized as a reliable provider of quality addiction treatment in the Cincinnati area.

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Situated in Lowell, MA, BrightView Health delivers a wide range of addiction recovery services tailored for both adults and young adults. The facility offers detoxification alongside various treatment options, including intensive outpatient, outpatient, and day programs. Employing proven methods such as brief interventions, cognitive behavioral therapy, and community reinforcement with vouchers, this center serves adult men and women, pregnant and postpartum women, as well as individuals across the gender spectrum. With an emphasis on high-quality care and specialized treatment, BrightView Health is committed to supporting individuals on their journey to sustained recovery from addiction.

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Brockton, MA

BrightView Health, situated in Brockton, MA, provides extensive services for addiction recovery. This center focuses on detox and treatment for both adults and young adults dealing with substance use issues. Various treatment options are available, such as intensive outpatient, outpatient, and daytime programs. BrightView Health emphasizes tailored care through methods including brief interventions, cognitive behavioral therapy, and community reinforcement alongside vouchers. Specialized programs are designed for adult men, women, and pregnant or postpartum individuals, ensuring gender-specific support for all clients. The center is committed to delivering high-quality and personalized assistance for those on their journey to overcome addiction.

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Somerville, MA

At BrightView Health in Somerville, MA, individuals can access a full spectrum of care designed to combat addiction. Their offerings encompass detoxification and the treatment of substance use disorders, featuring various levels of support including intensive outpatient, standard outpatient, and day treatment/partial hospitalization programs. The facility employs scientifically proven methods such as brief intervention, cognitive behavioral therapy, and community reinforcement with voucher incentives. BrightView Health caters to distinct groups with specific programs for adult males, adult females, and pregnant or postpartum women, while also welcoming adults and young adults of any gender. Dedicated to delivering exceptional care and personalized recovery paths, this center is committed to guiding those seeking to overcome addiction.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)