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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Brighton Recovery Center

Situated in Ogden, UT, Brighton Recovery Center provides a wide array of both long-term and short-term residential treatment options for individuals facing substance use disorders and related mental health challenges, applicable to both adults and children. The facility is adept in 12-step facilitation, anger management techniques, and brief intervention strategies. It offers specialized programs designed for adult men and women, while also supporting clients who have gone through experiences of intimate partner or domestic violence. Emphasizing care for both adult and young adult demographics, Brighton Recovery Center is committed to delivering personalized treatment, fostering a nurturing atmosphere conducive to healing and recovery.

Brighton Recovery Center
Salt Lake City, UT

At Brighton Recovery Center in Salt Lake City, UT, individuals can find extensive support for their recovery journeys. The facility focuses on addressing addiction and simultaneously supports those navigating concurrent significant mental health challenges or emotional distress. Brighton Recovery Center provides flexible program durations, including extended stays, shorter commitments, and round-the-clock residential care, all designed to adapt to individual requirements. They offer distinct therapeutic tracks for adult men and women and provide specialized assistance for survivors of intimate partner or domestic abuse. Employing proven techniques like 12-step integration, emotional regulation training, and concise intervention strategies, this center is dedicated to the health of adults and young adults, ensuring gender-sensitive treatment for all.

Brightview Health
Portsmouth, OH

Brightview Health, located in Portsmouth, OH, delivers a wide range of addiction treatment options for both adults and young adults. The facility specializes in detox and substance use therapies, including intensive outpatient, outpatient, and outpatient detox programs. Emphasizing a customized approach, the center implements evidence-based practices such as cognitive behavioral therapy, anger management, and brief intervention techniques. Additionally, Brightview Health provides unique programs catering to the LGBTQ community as well as pregnant and postpartum women. Committed to offering excellent care, the center supports clients of all genders in their journey toward recovery with a focus on effective and empathetic treatment solutions.

Bristlecone Family Resources

Bristlecone Family Resources, situated in Reno, NV, delivers thorough addiction recovery programs for adolescents and adults. They provide detox, substance use therapy, and sober living options, including intensive outpatient, long-term residential, and standard outpatient services. Utilizing targeted methods like 12-step facilitation, anger management, and brief intervention, Bristlecone Family Resources serves active military members, adult men, and adult women. Their gender-specific care ensures individualized support for males and females. Renowned for excellent treatment and personalized plans, this center is committed to fostering enduring sobriety.

BriteLife Recovery at Hanover

Situated in Hanover, PA, BriteLife Recovery at Hanover delivers an extensive array of services aimed at those in need of detoxification and substance abuse treatment. The facility features hospital inpatient detox services, substance use treatment, and round-the-clock inpatient care. Utilizing methods like 12-step facilitation, anger management, and brief intervention, BriteLife Recovery at Hanover supports adult men and women, including those in active military service. Focused on providing specialized programs for both adults and young adults, this center prioritizes effective care and guidance for individuals as they pursue their recovery goals.

Brockton Neighborhood Health Center

Brockton Neighborhood Health Center, situated in Brockton, MA, delivers extensive outpatient services for adults facing substance use challenges along with serious mental health disorders, as well as for children dealing with significant emotional issues. The center specializes in outpatient care utilizing medications like methadone, buprenorphine, or naltrexone, along with regular outpatient services and targeted programs for individuals with HIV/AIDS, dual diagnoses, and pregnant or postpartum women. Treatment methodologies incorporate brief interventions, cognitive behavioral therapy, and motivational incentives through contingency management. Catering to both male and female clients, this center prioritizes customized care for adults and youths, focusing on comprehensive support to aid individuals in their recovery journey.

Brockton Neighborhood Health Center

Situated in Brockton, MA, the Brockton Neighborhood Health Center provides tailored substance use treatment specifically designed for adults and young adults. This establishment offers outpatient services that include methadone, buprenorphine, and naltrexone treatment, with an emphasis on preventing relapse through custom care plans. Dedicated to delivering high-quality support, the center serves both men and women looking for extensive assistance on their path to recovery. The Brockton Neighborhood Health Center is distinguished by its personalized programs, which guarantee that every individual obtains the specific care necessary for sustaining long-term sobriety.

Bronx Lebanon Hospital Center

Situated in the Bronx, NY, Bronx Lebanon Hospital Center delivers extensive treatment options for adults and young adults facing substance use challenges along with severe mental health disorders. The facility features inpatient services and round-the-clock supervision, emphasizing a holistic approach to recovery. Customized programs for both men and women allow for personalized treatment experiences. The center prioritizes the distinct requirements of each gender, creating a nurturing and secure atmosphere for rehabilitation. Bronx Lebanon Hospital Center is committed to offering top-tier care to assist individuals in conquering addiction and attaining enduring recovery.

BronxCare Health System

BronxCare Health System, located in the Bronx, NY, presents an extensive array of outpatient treatment options aimed at individuals pursuing recovery from substance use. This center features specialized programs designed for adult males, adult females, and clients living with HIV or AIDS. Emphasizing cognitive behavioral therapy, anger management, and brief intervention strategies, it offers services to adults and young adults across all gender identities. The facility provides tailored outpatient options, including methadone/buprenorphine or naltrexone treatments, ensuring personalized care. BronxCare Health System is committed to delivering high-quality, evidence-based services to assist individuals in their recovery journey and enhance their mental well-being.

Brooklyn Hospital Center

The Brooklyn Hospital Center, situated in Brooklyn, New York, delivers extensive inpatient detoxification and addiction treatment services. This institution is equipped to provide tailored care for active military members, adult males, and adult females. Employing strategies such as 12-step facilitation, anger management, and brief interventions, the center supports both adult and adolescent individuals regardless of gender. Clients receive personalized, top-tier support throughout their healing process. For those needing robust treatment for addiction, the Brooklyn Hospital Center is committed to offering the essential tools and help for a sustained recovery.

Brightside Recovery Ltd

Brightside Recovery Ltd, situated in Ottawa, IL, provides a range of outpatient services, including intensive, standard, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Their treatment framework encompasses strategies for brief intervention, relapse prevention, and offers the convenience of telemedicine and telehealth therapy. The center is equipped to offer tailored care to adult men and women, with particular attention given to those impacted by intimate partner or domestic violence. Serving both adults and young adults, Brightside Recovery Ltd is dedicated to offering effective and individualized support for those on their journey to recovery from substance use disorders.

Brighton Recovery Center

Brighton Recovery Center, located in Ogden, UT, provides specialized treatment for substance use disorders and co-occurring mental health issues for adults dealing with significant psychological challenges. This center offers a range of programs, including intensive outpatient, outpatient, and day treatment, focusing on approaches like 12-step facilitation, anger management, and brief intervention strategies. The center features distinct programs designed for adult men and women, particularly those who have faced intimate partner or domestic violence. Customized treatment plans are available for both adults and younger individuals, with dedicated support for male and female clients. Brighton Recovery Center prioritizes high-quality care and personalized treatment to foster sustainable recovery outcomes.

Brookdale Premier Addiction Recovery

Situated in Scotrun, PA, Brookdale Premier Addiction Recovery delivers extensive recovery solutions for both adults and young adults grappling with addiction. This facility specializes in hospital-based detoxification and treatment services aimed at addressing substance use disorders, while also offering targeted support for those with concurrent mental health challenges. Emphasizing techniques such as 12-step facilitation, anger management, and brief intervention, Brookdale Premier Addiction Recovery customizes its approaches to cater to the distinct needs of every client. Additionally, there are specialized programs available for active duty military personnel, as well as specific offerings for adult men and women. The center is dedicated to providing high-quality care in a nurturing atmosphere for individuals on their path to recovery.

Brightside Recovery Ltd

Brightside Recovery Ltd, located in Washington, IL, provides a wide range of treatment services for individuals struggling with substance use issues, targeting both adults and young adults. The facility features intensive outpatient therapy, as well as outpatient programs, including options for methadone, buprenorphine, or naltrexone treatment. Emphasizing personalized care, Brightside Recovery Ltd utilizes techniques such as brief interventions, cognitive behavioral therapy, and motivational interviewing to address the unique needs of each client. The center primarily focuses on supporting adult men and women, including those affected by intimate partner or domestic violence. With a strong commitment to delivering high-quality care, this center strives to assist individuals on their journey to recovery.

Brook Hospital
Louisville, KY

Brook Hospital, situated in Louisville, KY, delivers extensive addiction recovery services for both adults and children. This facility offers inpatient detoxification and treatment for those grappling with substance use disorders, and it also provides targeted support for individuals who have co-existing mental health challenges. Emphasizing interventions that are brief, along with strategies for preventing relapse and counseling related to substance use disorders, Brook Hospital customizes its approach to address the specific needs of each individual. The center is particularly recognized for its programs designed for clients facing both mental health and substance use issues, ensuring that all patients receive thorough and effective care. Catering to both men and women, Brook Hospital is committed to offering high-quality, research-informed treatment in a nurturing setting.

Brighton Center Inc

Brighton Center Inc, situated in Brighton, MI, delivers thorough outpatient programs for detox and addiction recovery. Their services include outpatient detoxification, medication-assisted treatment with methadone, buprenorphine, or naltrexone, and therapeutic modalities such as 12-step support, anger management, and brief counseling. Brighton Center Inc is dedicated to personalized treatment for adult men and women, offering carefully crafted programs for effective and customized substance use disorder care.

Bronx Outreach Center

The Bronx Outreach Center, situated in Bronx, NY, provides extensive outpatient care for addiction and co-occurring mental health conditions, serving both adults and young individuals. Their specialized services include outpatient detox, medication-assisted treatment with methadone or buprenorphine, and naltrexone therapy. Employing evidence-based strategies like cognitive behavioral therapy, anger management, and brief intervention, they deliver personalized treatment plans. The center supports various populations, including active duty military personnel, teenagers, and adult men, and welcomes both male and female clients of all ages, committed to offering effective recovery support.

Brook Hospital
Louisville, KY

Brook Hospital in Louisville, KY, delivers extensive care for addiction. This center provides inpatient detox and treatment for both young people and adults. Their approach incorporates 12-step principles, cognitive behavioral strategies, and short-term interventions. Brook Hospital is equipped to assist individuals facing both mental health challenges and substance use issues, with tailored programs for adult males and adolescents. The availability of transitional living and halfway house accommodations supports a complete recovery journey. Their gender-tailored treatment plans are designed for male and female patients, focusing on personalized attention and fostering sustained sobriety.

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Brighter Heights Maine, located in Belfast, ME, provides targeted outpatient care for adults struggling with substance use and co-occurring severe mental health challenges, as well as children experiencing significant emotional disturbances. Their treatment modalities encompass cognitive behavioral therapy, motivational interviewing, and specialized counseling for substance use disorders. A key aspect of their service is a personalized strategy, adapting treatment plans to the specific requirements of each individual. Brighter Heights Maine serves adults and young adults across the gender spectrum. Beyond standard outpatient services, they also offer medication-assisted treatment, including methadone, buprenorphine, or naltrexone, to support individuals on their journey to recovery in a nurturing setting.

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Brookdale Hospital Medical Center located in Brooklyn, NY, provides targeted treatment for adults dealing with substance use issues alongside serious mental health disorders or emotional challenges in children. The center features a range of outpatient initiatives, including intensive outpatient programs and options for methadone, buprenorphine, or naltrexone therapy. Their treatment philosophy incorporates elements like 12-step support, anger management strategies, and short intervention services. With specialized programs designed for men and women, Brookdale Hospital Medical Center serves a wide array of patients. It offers dedicated programs for both adults and younger individuals, ensuring gender-specific care for both sexes. Clients can anticipate thorough and high-quality support at this establishment.

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Brookdale Hospital Medical Center in Brooklyn, NY, provides extensive addiction treatment services and distinct care for adults with co-occurring severe mental health issues and children experiencing serious emotional difficulties. Their offerings encompass intensive outpatient programs, general outpatient services, and outpatient medication-assisted treatment (methadone, buprenorphine, or naltrexone). Emphasizing strategies like 12-step integration, emotional regulation techniques, and short-term counseling, this institution delivers personalized support for adult males, adult females, and LGBTQ+ individuals. Catering to adults and young adults across all gender identities, Brookdale Hospital Medical Center delivers high-quality support in a nurturing setting to aid those on their journey to healing.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)