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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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BrightView Health

BrightView Health in Dayton, OH, is a dedicated facility providing extensive care for adults and adolescents grappling with addiction and co-occurring mental health challenges. Their services include intensive outpatient programs, outpatient detox, and outpatient counseling, incorporating techniques such as cognitive behavioral therapy and anger management. This location is notable for its tailored programs designed for LGBTQ individuals and expectant/new mothers. Prioritizing personalized treatment plans, BrightView Health delivers effective recovery support to both men and women addressing substance dependence.

BrightView Health

BrightView Health in Maumee, OH, delivers complete substance abuse recovery solutions for adults and younger individuals facing addiction challenges. The center features distinct treatment tracks for LGBTQ+ clients and expectant or new mothers, guaranteeing equitable and customized support. Employing cognitive behavioral therapy, anger management strategies, and brief intervention methods, the facility offers outpatient detox and intensive outpatient care. BrightView Health prioritizes high-quality treatment and personalized assistance for all clients, men and women alike, on their journey to sobriety. This institution is committed to offering successful recovery programs within a friendly and encouraging atmosphere.

BrightView Health
Mansfield, OH

BrightView Health, situated in Mansfield, OH, delivers thorough addiction recovery solutions for adults and adolescents. This center offers detox and substance abuse treatment via intensive outpatient, standard outpatient, and outpatient detox options. Employing methods such as anger management, brief intervention, and cognitive behavioral therapy, the facility customizes treatment to each person's unique requirements. A notable feature of BrightView Health is its dedicated LGBTQ+ program, specifically designed for individuals who identify as lesbian, gay, bisexual, transgender, and queer/questioning. Committed to high standards of care, this location accepts male and female patients in pursuit of successful and encouraging rehabilitation.

BrightView Health
Fairfield, OH

BrightView Health, located in Fairfield, OH, delivers a complete spectrum of care for substance use disorders. Their services encompass detox and addiction treatment via intensive outpatient, standard outpatient, and outpatient detox options. Employing methodologies like anger management, brief intervention, and cognitive behavioral therapy, this facility serves adult and young adult clients across all gender identities. Specialized programs tailored for LGBTQ individuals and expectant or new mothers underscore the center's dedication to a diverse and supportive environment. Prioritizing high-quality, research-backed treatment, BrightView Health stands as a reliable choice for individuals pursuing impactful and empathetic recovery.

BrightView Health

BrightView Health, situated in Paris, KY, delivers a full spectrum of addiction recovery solutions for adults and younger adults. The facility offers detox and comprehensive substance use disorder treatment via intensive outpatient, standard outpatient, and day programs. Employing therapeutic modalities like anger management, brief intervention, and CBT, BrightView Health customizes its offerings to meet each client's unique requirements. This center provides personalized care to both male and female individuals pursuing effective rehabilitation. If a nurturing setting focused on high-quality support and bespoke recovery strategies is what you seek, BrightView Health is committed to guiding individuals toward lasting sobriety.

Bristlecone Family Resources

Bristlecone Family Resources, situated in Reno, NV, delivers thorough addiction recovery programs for adolescents and adults. They provide detox, substance use therapy, and sober living options, including intensive outpatient, long-term residential, and standard outpatient services. Utilizing targeted methods like 12-step facilitation, anger management, and brief intervention, Bristlecone Family Resources serves active military members, adult men, and adult women. Their gender-specific care ensures individualized support for males and females. Renowned for excellent treatment and personalized plans, this center is committed to fostering enduring sobriety.

BriteLife Recovery at Hanover

Situated in Hanover, PA, BriteLife Recovery at Hanover delivers an extensive array of services aimed at those in need of detoxification and substance abuse treatment. The facility features hospital inpatient detox services, substance use treatment, and round-the-clock inpatient care. Utilizing methods like 12-step facilitation, anger management, and brief intervention, BriteLife Recovery at Hanover supports adult men and women, including those in active military service. Focused on providing specialized programs for both adults and young adults, this center prioritizes effective care and guidance for individuals as they pursue their recovery goals.

Brockton Neighborhood Health Center

Brockton Neighborhood Health Center, situated in Brockton, MA, delivers extensive outpatient services for adults facing substance use challenges along with serious mental health disorders, as well as for children dealing with significant emotional issues. The center specializes in outpatient care utilizing medications like methadone, buprenorphine, or naltrexone, along with regular outpatient services and targeted programs for individuals with HIV/AIDS, dual diagnoses, and pregnant or postpartum women. Treatment methodologies incorporate brief interventions, cognitive behavioral therapy, and motivational incentives through contingency management. Catering to both male and female clients, this center prioritizes customized care for adults and youths, focusing on comprehensive support to aid individuals in their recovery journey.

Brockton Neighborhood Health Center

Situated in Brockton, MA, the Brockton Neighborhood Health Center provides tailored substance use treatment specifically designed for adults and young adults. This establishment offers outpatient services that include methadone, buprenorphine, and naltrexone treatment, with an emphasis on preventing relapse through custom care plans. Dedicated to delivering high-quality support, the center serves both men and women looking for extensive assistance on their path to recovery. The Brockton Neighborhood Health Center is distinguished by its personalized programs, which guarantee that every individual obtains the specific care necessary for sustaining long-term sobriety.

Bronx Lebanon Hospital Center

Situated in the Bronx, NY, Bronx Lebanon Hospital Center delivers extensive treatment options for adults and young adults facing substance use challenges along with severe mental health disorders. The facility features inpatient services and round-the-clock supervision, emphasizing a holistic approach to recovery. Customized programs for both men and women allow for personalized treatment experiences. The center prioritizes the distinct requirements of each gender, creating a nurturing and secure atmosphere for rehabilitation. Bronx Lebanon Hospital Center is committed to offering top-tier care to assist individuals in conquering addiction and attaining enduring recovery.

BronxCare Health System

BronxCare Health System, located in the Bronx, NY, presents an extensive array of outpatient treatment options aimed at individuals pursuing recovery from substance use. This center features specialized programs designed for adult males, adult females, and clients living with HIV or AIDS. Emphasizing cognitive behavioral therapy, anger management, and brief intervention strategies, it offers services to adults and young adults across all gender identities. The facility provides tailored outpatient options, including methadone/buprenorphine or naltrexone treatments, ensuring personalized care. BronxCare Health System is committed to delivering high-quality, evidence-based services to assist individuals in their recovery journey and enhance their mental well-being.

Brooklyn Hospital Center

The Brooklyn Hospital Center, situated in Brooklyn, New York, delivers extensive inpatient detoxification and addiction treatment services. This institution is equipped to provide tailored care for active military members, adult males, and adult females. Employing strategies such as 12-step facilitation, anger management, and brief interventions, the center supports both adult and adolescent individuals regardless of gender. Clients receive personalized, top-tier support throughout their healing process. For those needing robust treatment for addiction, the Brooklyn Hospital Center is committed to offering the essential tools and help for a sustained recovery.

BrightView Health
Chillicothe, OH

BrightView Health in Chillicothe, OH, delivers complete care for substance dependency, encompassing withdrawal management and therapy. Available services include structured intensive outpatient care, general outpatient treatment, and outpatient detox. The clinic utilizes proven methods like anger management techniques, brief intervention strategies, and cognitive behavioral therapy. Targeted support is offered for LGBTQ individuals and mothers who are pregnant or have recently given birth. BrightView Health welcomes adults and young adults across all gender identities. This institution is committed to high-standard treatment and tailored programs, aiding individuals in their path to regaining health.

Brookdale Premier Addiction Recovery

Situated in Scotrun, PA, Brookdale Premier Addiction Recovery delivers extensive recovery solutions for both adults and young adults grappling with addiction. This facility specializes in hospital-based detoxification and treatment services aimed at addressing substance use disorders, while also offering targeted support for those with concurrent mental health challenges. Emphasizing techniques such as 12-step facilitation, anger management, and brief intervention, Brookdale Premier Addiction Recovery customizes its approaches to cater to the distinct needs of every client. Additionally, there are specialized programs available for active duty military personnel, as well as specific offerings for adult men and women. The center is dedicated to providing high-quality care in a nurturing atmosphere for individuals on their path to recovery.

BrightView Health

BrightView Health in Hyannis, MA delivers a full spectrum of addiction recovery solutions. They offer medically supervised detoxification and treatment via intensive outpatient, standard outpatient, and day programs. Utilizing proven methods like cognitive behavioral therapy and community reinforcement with vouchers, BrightView Health customizes care for adult men, adult women, expectant and new mothers, and young adults. Their specialized tracks are designed for specific demographics, guaranteeing individualized support for everyone pursuing sobriety. BrightView Health is dedicated to delivering exceptional and successful care within a nurturing setting.

Brook Hospital
Louisville, KY

Brook Hospital, situated in Louisville, KY, delivers extensive addiction recovery services for both adults and children. This facility offers inpatient detoxification and treatment for those grappling with substance use disorders, and it also provides targeted support for individuals who have co-existing mental health challenges. Emphasizing interventions that are brief, along with strategies for preventing relapse and counseling related to substance use disorders, Brook Hospital customizes its approach to address the specific needs of each individual. The center is particularly recognized for its programs designed for clients facing both mental health and substance use issues, ensuring that all patients receive thorough and effective care. Catering to both men and women, Brook Hospital is committed to offering high-quality, research-informed treatment in a nurturing setting.

Bronx Outreach Center

The Bronx Outreach Center, situated in Bronx, NY, provides extensive outpatient care for addiction and co-occurring mental health conditions, serving both adults and young individuals. Their specialized services include outpatient detox, medication-assisted treatment with methadone or buprenorphine, and naltrexone therapy. Employing evidence-based strategies like cognitive behavioral therapy, anger management, and brief intervention, they deliver personalized treatment plans. The center supports various populations, including active duty military personnel, teenagers, and adult men, and welcomes both male and female clients of all ages, committed to offering effective recovery support.

Brook Hospital
Louisville, KY

Brook Hospital in Louisville, KY, delivers extensive care for addiction. This center provides inpatient detox and treatment for both young people and adults. Their approach incorporates 12-step principles, cognitive behavioral strategies, and short-term interventions. Brook Hospital is equipped to assist individuals facing both mental health challenges and substance use issues, with tailored programs for adult males and adolescents. The availability of transitional living and halfway house accommodations supports a complete recovery journey. Their gender-tailored treatment plans are designed for male and female patients, focusing on personalized attention and fostering sustained sobriety.

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BrightView Health in Lynn, MA, delivers extensive addiction recovery care for adults and adolescents. The facility offers detoxification and a range of substance use treatments, including intensive outpatient, outpatient, and day treatment modalities. Employing scientifically validated methods such as cognitive behavioral therapy, brief intervention, and community reinforcement with voucher incentives, this center crafts individualized treatment strategies. Distinct programs are available for adult men, adult women, and women who are pregnant or have recently given birth, providing targeted support. Committed to high standards and individualized assistance, BrightView Health serves as a reliable provider of successful rehabilitation services within a nurturing atmosphere.

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Brookdale Hospital Medical Center located in Brooklyn, NY, provides targeted treatment for adults dealing with substance use issues alongside serious mental health disorders or emotional challenges in children. The center features a range of outpatient initiatives, including intensive outpatient programs and options for methadone, buprenorphine, or naltrexone therapy. Their treatment philosophy incorporates elements like 12-step support, anger management strategies, and short intervention services. With specialized programs designed for men and women, Brookdale Hospital Medical Center serves a wide array of patients. It offers dedicated programs for both adults and younger individuals, ensuring gender-specific care for both sexes. Clients can anticipate thorough and high-quality support at this establishment.

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Brookdale Hospital Medical Center in Brooklyn, NY, provides extensive addiction treatment services and distinct care for adults with co-occurring severe mental health issues and children experiencing serious emotional difficulties. Their offerings encompass intensive outpatient programs, general outpatient services, and outpatient medication-assisted treatment (methadone, buprenorphine, or naltrexone). Emphasizing strategies like 12-step integration, emotional regulation techniques, and short-term counseling, this institution delivers personalized support for adult males, adult females, and LGBTQ+ individuals. Catering to adults and young adults across all gender identities, Brookdale Hospital Medical Center delivers high-quality support in a nurturing setting to aid those on their journey to healing.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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