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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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California Recovery Center

California Recovery Center in Roseville, CA, delivers holistic addiction treatment for adults and young adults. This establishment features extended residential stays, inpatient detoxification, and round-the-clock residential supervision. Emphasizing 12-step principles, emotional regulation techniques, and short-term counseling, the center supports individuals facing dual diagnoses of substance abuse and significant mental health conditions. Tailored services are provided for active military members, adult males, and adult females. Catering to both genders, the center guarantees high-quality assistance for those pursuing sobriety and managing concurrent mental health concerns.

California Recovery Center

California Recovery Center, located in Roseville, CA, delivers expert care for individuals battling addiction and co-occurring mental health conditions. They offer comprehensive services for adults experiencing substance use disorders or serious mental health challenges, as well as for children with serious emotional disturbances. Their programs include extended residential stays, immediate detoxification services, and continuous round-the-clock support. Employing proven methods such as 12-step integration, emotional regulation techniques, and brief counseling, the center crafts personalized recovery plans. They also provide specialized tracks for active military personnel, adult men, and adult women. Catering to a broad spectrum of adults and young adults, California Recovery Center is dedicated to providing superior treatment and assistance for those on their journey to lasting sobriety.

California Rehab Campus LLC

Situated in Dana Point, CA, California Rehab Campus LLC delivers all-encompassing rehabilitation services aimed at adults and young adults dealing with substance use challenges and concurrent mental health conditions. This center features hospital-based inpatient detoxification along with treatment plans, specifically designed for individuals with dual diagnoses. Emphasizing evidence-based methodologies such as 12-step facilitation, anger management, and cognitive behavioral therapy, the facility prioritizes tailored care for every client. California Rehab Campus LLC supports both male and female clients, fostering a nurturing atmosphere for individuals dedicated to overcoming addiction and attaining sustainable recovery.

Calusa Recovery
Fort Myers, FL

Calusa Recovery, located in Fort Myers, FL, provides extensive support for substance abuse recovery and provides housing during the transition period. This center is particularly adept at addressing dual diagnoses, treating individuals struggling with addiction and significant mental health issues, and also offers specialized care for children experiencing emotional difficulties. Their primary treatment modalities include intensive outpatient programs and day treatment, incorporating strategies like 12-step facilitation, anger management, and brief intervention techniques. Calusa Recovery also has dedicated programs for active military personnel, teenagers, and adult men. Catering to individuals of all genders and age groups, the center is committed to delivering high-quality care and assistance to those pursuing a life free from addiction.

Cambridge Recovery Sober Living

Cambridge Recovery Sober Living, situated in Flanders, NJ, is a prominent residential establishment providing targeted support for substance abuse and interim housing for adult males. This extended-stay residential program integrates principles of the 12-step model, techniques for managing anger, and brief counseling strategies to foster recovery. The facility accommodates individuals facing dual diagnoses of substance use disorders and significant mental health conditions, including those with a history of sexual trauma. Serving active military members, adult men, and clients ranging from young adults to older individuals, this center delivers thorough care within a male-only setting. For effective treatment within a nurturing community, Cambridge Recovery Sober Living stands out as an excellent option for individuals pursuing sustained sobriety.

Camelback Recovery Treatment Center

Camelback Recovery Treatment Center located in Phoenix, AZ, provides a wide array of addiction treatment options for both adults and young adults. The center specializes in detoxification, treatment for substance use disorders, and personalized support for those facing concurrent mental health challenges. Their offerings encompass intensive outpatient programs, outpatient day initiatives, and partial hospitalization options. Emphasizing methods such as 12-step support, anger management strategies, and brief intervention techniques, the center customizes treatment approaches to suit the unique needs of each individual. Additionally, the center stands out by offering specialized services for clients who have experienced trauma and those with dual diagnoses. Camelback Recovery Treatment Center is dedicated to delivering high-quality care to all clients, regardless of gender, on their path to recovery.

Camillus House

Camillus House in Miami, FL, is dedicated to providing extensive substance abuse recovery services for adults and adolescents facing addiction and co-occurring psychological conditions. The center delivers specialized support through its extended stay residential, intensive outpatient, and standard outpatient options, employing approaches like 12-step integration, emotional regulation training, and cognitive restructuring. Distinctive offerings are available for adult males, adult females, and individuals impacted by domestic abuse. This institution emphasizes high-standard care, delivering individualized plans for both male and female participants within a nurturing and expert setting.

Campbell County Health

Campbell County Health, located in Gillette, WY, provides extensive rehabilitation services for both adults and children facing substance use challenges alongside significant mental health disorders. The center features both intensive outpatient and outpatient treatment options, which include therapies using methadone and buprenorphine. Emphasizing techniques such as anger management, brief interventions, and cognitive behavioral therapy, this facility customizes its programs to meet the unique requirements of each individual. Additionally, special initiatives are available for active duty members of the military as well as distinct programs for adult men and women. Catering to adults and seniors across all genders, Campbell County Health is committed to delivering effective and tailored addiction treatment solutions.

Calvary Healing Center

Calvary Healing Center, located in Phoenix, AZ, provides a wide range of programs aimed at treating addiction for both adults and children facing co-occurring mental health issues. This center has tailored services for military personnel, as well as specific programs for adult men and women. They offer hospital-based detoxification and treatment that employs proven methods, including 12-step programs and cognitive-behavioral therapy. Catering to a diverse clientele that includes adults, seniors, and young adults of various genders, Calvary Healing Center prioritizes high-quality care through its inpatient services available around the clock. If you or someone you care about is looking for effective treatment for substance use in a nurturing setting, this center is committed to guiding individuals toward sustainable recovery.

Camelot of Staten Island Inc

Situated in Staten Island, NY, Camelot of Staten Island Inc is a premier rehabilitation facility dedicated to supporting adult men facing challenges related to substance use and serious co-occurring mental health disorders. The center features long-term residential programs, detox services, and round-the-clock support. Emphasizing approaches such as 12-step methods, anger management, and brief interventions, Camelot of Staten Island Inc customizes its treatment plans to meet the unique needs of each individual. Notably, the center offers specialized programs for those affected by intimate partner violence, domestic abuse, and sexual trauma. Catering to a diverse age range including adults, seniors, and young adults, Camelot of Staten Island Inc ensures high-quality, gender-responsive care for male clients in pursuit of thorough rehabilitation options.

Camelot of Staten Island Inc

Camelot of Staten Island Inc, situated in Staten Island, NY, delivers high-quality treatment for adult males struggling with addiction. This center focuses on long-term residential programs that encompass detox services and around-the-clock support. Emphasizing a 12-step approach, anger management techniques, and brief intervention strategies, it offers extensive care for individuals facing both substance abuse and severe mental health challenges. The facility also features tailored programs aimed at adults who have endured intimate partner violence or sexual trauma, distinguishing it from other centers. Catering to adults, seniors, and young adults, Camelot of Staten Island Inc ensures a secure and encouraging atmosphere for men committed to overcoming addiction.

Calvert County Behavioral Health

Calvert County Behavioral Health, situated in Chesapeake Beach, MD, delivers targeted outpatient services for adults and children dealing with substance use and related mental health issues. The center provides a variety of evidence-based approaches, including 12-step facilitation, anger management sessions, and short-term interventions, ensuring that care is customized to meet the individual requirements of each client. Specialized programs are available for those affected by sexual abuse, trauma, and co-occurring disorders. Catering to a diverse adult population, including seniors, the center also offers outpatient treatment using medications such as methadone, buprenorphine, and naltrexone. With an emphasis on high-quality and well-rounded care, Calvert County Behavioral Health stands as a reliable choice for individuals seeking effective treatment solutions.

Calvert County Behavioral Health

Located in Barstow, MD, Calvert County Behavioral Health specializes in providing tailored substance use treatment for adults dealing with serious mental health challenges as well as children facing significant emotional issues. The center features various treatment modalities, including intensive outpatient programs, outpatient services, and options utilizing methadone, buprenorphine, or naltrexone. Emphasizing the 12-step approach, anger management, and brief intervention strategies, this facility supports adolescents and individuals who have experienced intimate partner violence, domestic violence, and sexual abuse. Dedicated to offering thorough and personalized care, Calvert County Behavioral Health aims to foster sustainable recovery for both adults and seniors from all backgrounds.

Calvert County Behavioral Health

Calvert County Behavioral Health, located in Prince Frederick, MD, provides a wide range of outpatient services designed for individuals dealing with substance use and concurrent disorders, applicable to both adults and children. Their targeted programs are specifically designed for those who have experienced intimate partner violence, sexual abuse, and domestic violence. Emphasizing 12-step support, anger management strategies, and brief intervention techniques, the facility delivers personalized care for adult women and clients of all genders. Additionally, the center offers outpatient treatment options using methadone, buprenorphine, or naltrexone, along with ongoing outpatient services, to ensure a high standard of care for adults and seniors in need of recovery support in a nurturing atmosphere.

Calvert County Behavioral Health

Calvert County Behavioral Health, located in Lusby, MD, provides various outpatient services for adults and children dealing with substance use disorders and co-occurring mental health issues. The center focuses on tailored programs for those who have faced trauma, incidents of intimate partner violence, sexual abuse, and domestic conflicts. Employing different treatment techniques such as 12-step programs, anger management sessions, and short-term interventions, this facility serves clients of all genders, including elderly individuals. Whether individuals are looking for standard outpatient support or methadone/buprenorphine therapies, they can anticipate personalized, high-quality care at Calvert County Behavioral Health.

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Calumet County Department of, located in Chilton, WI, provides outpatient services for individuals of all ages struggling with substance use and co-occurring mental health conditions. Their comprehensive program incorporates anger management, cognitive behavioral therapy, and proven relapse prevention techniques. What distinguishes this facility is its tailored treatment plans, designed to meet the unique needs of adults and seniors across the gender spectrum. Committed to delivering high-quality care, the center fosters a secure and encouraging setting for those addressing addiction and mental wellness concerns. For those desiring personalized, scientifically-backed care, Calumet County Department of stands ready to assist you in achieving lasting recovery.

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Camelot Counseling Centers, located in Bronx, NY, provides focused outpatient care for adults dealing with substance use issues and concurrent severe mental health disorders, along with support for children's emotional challenges. Their offerings encompass 12-step programs, anger management, and short intervention strategies. This center delivers customized services for men and women, as well as individuals who have faced domestic or intimate partner violence. Catering to adult and young adult clients of various genders, Camelot Counseling Centers prioritizes personalized treatment and evidence-informed practices to foster recovery and enhance overall health.

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Camelot Counseling Services, situated in Jamaica, NY, delivers outpatient treatment for adults and young adults struggling with substance use disorders and co-occurring serious mental health conditions. The center is particularly adept at supporting those with a background of intimate partner or domestic violence. Employing methods like 12-step facilitation, anger management, and brief intervention, Camelot Counseling Services supports adult men and women on their journey to recovery. Their services encompass outpatient treatment with methadone/buprenorphine or naltrexone, providing thorough support. This facility is dedicated to high-quality care, aiming to equip individuals with the tools to conquer addiction and enhance their mental health.

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Camelot of Staten Island Inc, located in the Bronx, NY, specializes in outpatient treatment for adults dealing with substance use issues alongside significant mental health challenges or emotional difficulties. The center offers a variety of treatment methods, such as outpatient services for methadone/buprenorphine, standard outpatient care, and 12-step support systems. Emphasizing anger management and short-term interventions, this facility serves both men and women, including those affected by intimate partner violence. Additionally, programs designed for young adults ensure that clients of various ages receive the necessary care. Camelot of Staten Island Inc is recognized for its gender-sensitive treatment programs, providing effective rehabilitation support to male and female individuals seeking help for addiction.

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Camelot of Staten Island Inc, located in Staten Island, NY, provides outpatient detoxification and treatment for adults and young adults dealing with substance use issues. This center is particularly proficient in addressing co-occurring substance use disorders that occur alongside significant mental health challenges or emotional issues in children. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention strategies, the facility offers tailored programs for adult men and women, as well as those who have faced intimate partner or domestic abuse. Their comprehensive treatment plans are designed to meet the unique needs of both male and female clients, ensuring personalized care and guidance. Camelot of Staten Island Inc is committed to offering exemplary rehabilitation services aimed at assisting individuals on their recovery journey.

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Albany, NY

Camino Nuevo, situated in Albany, NY, delivers thorough outpatient care for individuals of all ages struggling with substance use. The center is particularly adept at addressing dual diagnoses, including substance use disorders alongside severe mental health conditions in adults or significant emotional challenges in children. Camino Nuevo offers outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, complemented by therapeutic strategies such as 12-step program integration, anger control techniques, and brief counseling. Dedicated services are available for active military members, adult males, and adult females, ensuring tailored support across different demographics. Clients receive effective, research-backed treatment within a nurturing setting geared towards sustained recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)