NWVCIL Logo
Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6655 results

CHC of Cape Cod Addiction

CHC of Cape Cod Addiction in Buzzards Bay, MA, provides outpatient services designed for those pursuing sobriety. The facility employs specific therapeutic strategies, including anger management techniques, brief intervention protocols, and motivational interviewing. They offer tailored programs for current military members, adult males, and adult females, accommodating a wide array of individuals. This center, serving adult and older adults of all genders, is dedicated to delivering effective, individualized care to foster long-term recovery. For thorough addiction treatment within a nurturing setting, consider CHC of Cape Cod Addiction.

CHC of Cape Cod Addiction Program

The CHC of Cape Cod Addiction Program in Mashpee, MA, provides extensive support for adults facing substance use challenges, including those with concurrent mental health conditions. This center features outpatient options such as medication-assisted treatment with methadone or buprenorphine, alongside general outpatient services. Employing therapeutic techniques like anger management and motivational interviewing, the program is tailored to meet the specific requirements of active duty military members, adult men, and women. Open to adults and seniors across all genders, this dedicated program is committed to delivering effective care to aid individuals in their path to sustained recovery.

CHOICE Program
Indianapolis, IN

Situated in Indianapolis, IN, the CHOICE Program delivers extensive services for addiction treatment. This center offers hospital inpatient detoxification, round-the-clock care, and outpatient services tailored for both adults and older adults. With a focus on substance use recovery, the facility serves female clients, including active military members, adult women, and young individuals. Employing evidence-based methods such as brief interventions, motivational interviewing, and relapse prevention strategies, the program is designed to provide customized care for every participant. Emphasizing high standards and specialized programs for diverse groups, the CHOICE Program is recognized as a reliable option for individuals in need of effective rehabilitation.

CHRIS 180 Inc
Atlanta, GA

CHRIS 180 Inc, located in Atlanta, GA, presents a wide array of addiction recovery services designed to meet the unique requirements of each client. The center specializes in intensive outpatient care, outpatient detox support, and various programs aimed at adults and older adults. Emphasizing techniques such as cognitive behavioral therapy, anger management, and brief interventions, clients receive tailored support for substance use disorders and co-occurring mental health issues. Additionally, specialized programs are offered for teenagers and young adults. CHRIS 180 Inc accommodates both men and women, fostering a welcoming and supportive atmosphere for everyone. Discover effective care and research-supported treatments at this center committed to guiding individuals toward long-term recovery.

CMS Dearborn Heights
Dearborn Heights, MI

CMS Dearborn Heights, situated in Dearborn Heights, MI, is a dedicated facility providing tailored substance use disorder therapy for adults and adolescents. This center delivers outpatient care, incorporating medication-assisted treatment with methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods like cognitive behavioral therapy, contingency management, and motivational interviewing, the program aids individuals on their path to recovery. A notable aspect of their approach is a specific focus on the needs of pregnant and new mothers. Serving both men and women, CMS Dearborn Heights offers comprehensive addiction treatment within a supportive outpatient environment.

CHI Health Mercy Psychiatric Associate

CHI Health Mercy Psychiatric Associates, located in Council Bluffs, IA, provides targeted outpatient services for individuals of all ages grappling with addiction and co-occurring mental health conditions. Their therapeutic framework integrates techniques such as anger control strategies, cognitive behavioral therapy, and concise intervention methods to deliver personalized treatment plans. The center supports adults and older adults with various medication-assisted treatment options, including methadone, buprenorphine, and naltrexone. By prioritizing a unique care path for every patient, CHI Health Mercy Psychiatric Associates is dedicated to assisting those in need of support for substance abuse and psychological well-being.

CHI Health Psychiatric Associates

Located in Omaha, NE, CHI Health Psychiatric Associates provides outpatient services for substance use treatment and addresses co-occurring disorders along with severe mental health challenges in adults, as well as emotional issues in children. The center employs techniques such as brief intervention, cognitive behavioral therapy, and motivational incentives to create personalized treatment plans that cater to individual needs. With a commitment to serving all genders across both adult and child/adolescent populations, this center prioritizes high-quality care to facilitate recovery and enhance overall wellness. CHI Health Psychiatric Associates is devoted to guiding individuals on their journey toward lasting recovery from addiction.

CLARE Matrix
Santa Monica, CA

Situated in Santa Monica, CA, CLARE Matrix stands out as a leading rehabilitation facility dedicated to detoxification and substance use recovery for adult males. The center provides various options including long-term residential stays, detoxification services, and around-the-clock residential treatment aimed at those who have faced intimate partner violence, domestic abuse, and sexual trauma. Emphasizing 12-step methods, anger management, and brief intervention strategies, CLARE Matrix delivers effective support for adults, seniors, and younger individuals on their path to recovery. With its focused programs and committed team, the center fosters a nurturing space for healing and personal development.

CLARE Matrix
Santa Monica, CA

CLARE Matrix, situated in Santa Monica, California, provides a wide range of addiction treatment options. The center focuses on detox services and substance abuse recovery, emphasizing long-term residential care. With an emphasis on 12-step support, anger management, and brief intervention techniques, CLARE Matrix serves adult men and women, including those affected by domestic violence or intimate partner abuse. This facility caters to both adults and young adults, offering customized care for both genders. CLARE Matrix is recognized for its high-quality treatment and individualized programs, making it a reliable option for individuals in need of rehabilitation.

CLARE Matrix
Santa Monica, CA

The CLARE Matrix facility in Santa Monica, California, delivers exceptional substance abuse recovery programs specifically designed for adult women. They excel in providing detox and ongoing treatment, with a structured long-term residential model. Their approach integrates 12-step principles, anger management techniques, and brief intervention strategies. CLARE Matrix is particularly attuned to the needs of women who have faced domestic violence, intimate partner abuse, or sexual trauma. Offering targeted care for adults, older adults, and young adults, the center is dedicated to providing thorough rehabilitation in a secure and supportive setting for its female clientele.

CHD
Greenfield, MA

CHD in Greenfield, MA, delivers expert outpatient care for individuals of all ages facing addiction and dual diagnoses. Employing proven therapeutic methods like cognitive behavioral therapy and anger management, the center addresses a spectrum of needs. They welcome both male and female patients and offer dedicated support for pregnant or new mothers, as well as those involved in the legal system. CHD provides medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient therapy. Committed to high standards and personalized recovery journeys, CHD stands as a reliable provider of rehabilitation solutions in Greenfield.

CKF Addiction Treatment Inc

CKF Addiction Treatment Inc, situated in Salina, KS, offers a wide array of services designed for those in need of assistance with substance use issues. The facility specializes in detoxification and intensive outpatient care, incorporating methods like 12-step principles and cognitive behavioral techniques. Unique programs are available for adult women as well as clients involved with the criminal justice system. CKF Addiction Treatment Inc accommodates both adults and youth, featuring gender-specific programs for males and females. The center provides various treatment formats, including outpatient options and medication-assisted therapies with methadone, buprenorphine, or naltrexone, focusing on high-quality care and research-backed practices to aid individuals on their recovery journey.

CMCSB Russell Co
Lebanon, VA

CMCSB Russell Co, situated in Lebanon, VA, delivers a wide range of outpatient services for individuals grappling with substance use issues and co-occurring mental health conditions, covering both adults and children. This center focuses on tailored therapeutic approaches, serving individuals from diverse backgrounds. By implementing well-established treatment methods like cognitive behavioral therapy, the Matrix Model, and motivational interviewing, CMCSB Russell Co fosters a nurturing atmosphere conducive to healing. The facility offers various outpatient options, including methadone/buprenorphine or naltrexone therapies, in addition to standard outpatient care, ensuring that each person receives high-quality, customized treatment plans to address their unique challenges with addiction and mental health.

CKF Addiction Treatment Inc

CKF Addiction Treatment Inc located in Abilene, KS, provides a wide range of substance use services for both adults and children/adolescents. The center features intensive outpatient programs, general outpatient services, and options for outpatient methadone, buprenorphine, or naltrexone treatment. Emphasizing methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, CKF Addiction Treatment Inc customizes treatment strategies to meet the unique needs of each patient. With expertise in working with criminal justice and forensic populations, this facility caters to both male and female clients. Renowned for its high-quality care and reliance on evidence-based practices, CKF Addiction Treatment Inc is committed to assisting individuals in overcoming addiction and attaining sustained recovery.

CKF Addiction Treatment Inc

CKF Addiction Treatment Inc, located in McPherson, KS, provides a thorough program for individuals battling substance use disorders. Their services encompass intensive outpatient, standard outpatient, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center is equipped to assist clients across all age groups, including adults and minors, and serves both men and women. Employing proven therapeutic methods like 12-step facilitation, motivational interviewing, and cognitive behavioral therapy, CKF Addiction Treatment Inc delivers personalized care. A significant area of expertise lies in their dedicated support for individuals involved with the criminal justice system. CKF Addiction Treatment Inc is committed to delivering high-quality, compassionate care in a recovery-focused setting.

Placeholder image
West Springfield, MA

CHD, situated in West Springfield, MA, delivers extensive outpatient treatment for adults dealing with substance use issues alongside severe mental health disorders, as well as for children facing significant emotional challenges. The facility offers a variety of outpatient services including methadone, buprenorphine, and naltrexone treatments, along with routine outpatient support. It also emphasizes skills such as anger management, brief interventions, and cognitive behavioral therapy. With a strong emphasis on tailored treatment plans, CHD serves adults, children, adolescents, and young adults of all genders. The center is recognized for its commitment to high-quality care and its welcoming atmosphere, ensuring a personalized and varied treatment experience.

Placeholder image
Orange, MA

Situated in Orange, MA, CHD stands out as a premier rehabilitation facility that delivers a variety of outpatient services aimed at addressing substance use, co-occurring mental health disorders in adults, and emotional challenges in children. The center features specialized programs catering to clients involved in the criminal justice system, ensuring personalized treatment for both men and women. CHD employs evidence-based methodologies including cognitive behavioral therapy, anger management, and brief therapeutic interventions to ensure high-quality support for people of all ages. Whether clients require standard outpatient services or specific therapies like methadone, buprenorphine, or naltrexone, CHD is committed to aiding individuals in their recovery journey.

Placeholder image
Waterbury, CT

CJR Waterbury, situated in Waterbury, CT, delivers extensive outpatient care for individuals facing substance use challenges and related mental health disorders, serving both adults and children. This facility features tailored programs specifically designed for adolescents and young adults, as well as for those with mental health concerns. Treatment modalities offered encompass anger management, cognitive behavioral therapy, and various brief intervention techniques. CJR Waterbury serves a diverse clientele, including men, women, seniors, and adults. Prioritizing personalized care and high-quality treatment, this center provides outpatient options involving methadone, buprenorphine, or naltrexone, in conjunction with standard outpatient services. If you or someone you know is looking for reliable rehabilitation options, CJR Waterbury stands out as a reputable option.

Placeholder image
Santa Monica, CA

Situated in Santa Monica, CA, CLARE Matrix is a leading rehabilitation facility that delivers a variety of specialized services aimed at individuals aiming to overcome substance use challenges. The center features all-encompassing long-term residential treatments, including detoxification and round-the-clock support. Emphasizing 12-step methods, anger management strategies, and concise intervention techniques, CLARE Matrix is dedicated to serving adults and young adults of any gender. What distinguishes this center are its unique programs designed for individuals who have faced trauma, intimate partner violence, domestic abuse, and sexual assault. With a strong dedication to high-quality care, CLARE Matrix shines as a symbol of hope for those embarking on their recovery journey.

Placeholder image
Los Angeles, CA

CLARE Matrix in Los Angeles, CA, provides comprehensive outpatient services for adults grappling with substance use disorders. Their programs are designed for both men and women, offering specialized support for individuals who have faced domestic abuse. CLARE Matrix excels in incorporating 12-step principles, anger management techniques, and brief intervention strategies into their treatment plans. They are committed to delivering high-quality, personalized care for adults and young adults on their path to recovery. Recognizing the varied needs of those seeking sobriety, CLARE Matrix offers outpatient options such as methadone, buprenorphine, or naltrexone. For those in search of empathetic and thorough treatment within a nurturing atmosphere, CLARE Matrix is a distinguished choice for embarking on your recovery.

Placeholder image
Cedar Bluff, VA

Situated in Cedar Bluff, VA, CMCSB delivers extensive outpatient treatment for substance use issues among both adults and young adults. The center excels in addressing co-occurring substance use disorders alongside significant mental health challenges or emotional difficulties, offering customized care through proven methodologies like cognitive behavioral therapy and motivational interviewing. Programs are designed to meet the distinct requirements of each individual, including options for outpatient treatment with methadone, buprenorphine, or naltrexone. CMCSB is committed to providing high-quality support for all clients, regardless of gender. If you are looking for effective, tailored treatment in a nurturing setting, this center is focused on guiding you toward sustainable recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)