Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.
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Located in Los Angeles, CA, CNV Detox Inc delivers a wide range of services aimed at treating addiction. This center specializes in hospital-based inpatient detox and therapeutic programs designed for both adults and young adults who are grappling with substance abuse and related mental health challenges. CNV Detox Inc utilizes methods such as 12-step support, brief interventions, and cognitive behavioral therapy to create customized treatment plans. The facility offers special programs tailored for adult men, adult women, and individuals with dual diagnoses. Its dedication to high-quality care and individualized treatment options positions CNV Detox Inc as a leading option for effective rehabilitation.

CODAC Health Recovery and Wellness Inc, located in Tucson, AZ, delivers a broad spectrum of services designed for those looking to recover from substance abuse and related mental health issues. The facility offers detoxification, as well as intensive outpatient programs and outpatient treatments utilizing methadone, buprenorphine, or naltrexone. Emphasizing therapeutic techniques such as anger management, cognitive behavioral therapy, and brief interventions, CODAC Health Recovery and Wellness Inc customizes its offerings to fit each individual’s specific requirements. Special initiatives are available for adult men, adult women, and individuals who have faced trauma. Catering to both adult and young adult populations of all genders, the center is dedicated to providing exceptional care and support during the recovery process.

CODAC Health Recovery and Wellness Inc, located in Tucson, AZ, provides a wide variety of outpatient treatment options for adults and young adults dealing with substance use issues alongside mental health concerns. The center features unique services, including outpatient treatments with methadone, buprenorphine, or naltrexone, as well as cognitive behavioral therapy, anger management sessions, and brief intervention techniques. Emphasizing personalized treatment, CODAC Health Recovery and Wellness Inc serves adult men, women, and individuals who have undergone trauma. Their programs are designed to address the specific needs of each person, ensuring that all clients receive exceptional support on their journey to recovery.

CODAC Health Recovery and Wellness Inc. in Tucson, Arizona, is dedicated to providing comprehensive outpatient care for those struggling with substance use disorders. They also offer specialized support for individuals facing the challenges of co-occurring substance use and serious mental health conditions. Their treatment options include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient services. The center employs evidence-based approaches such as anger management, brief intervention, and cognitive behavioral therapy. CODAC Health Recovery and Wellness Inc. welcomes adult men and women, including those with a history of trauma, and provides tailored programs for adults and young adults, aiming to foster lasting recovery and overall well-being.

Situated in Sterling Heights, MI, CMS Sterling Heights stands out as a premier rehabilitation center dedicated to addressing substance use issues among adults and young adults. This center provides a range of outpatient services, featuring treatments such as methadone/buprenorphine or naltrexone therapies. Utilizing evidence-based methods like cognitive behavioral therapy, motivational interviewing, and contingency management, CMS Sterling Heights tailors its care to meet the unique needs of each individual. The center also has specialized programs for pregnant and postpartum women. Committed to delivering high-quality and gender-specific treatment for both men and women, this facility is focused on empowering individuals in their recovery journey.

CODA Inc, situated in Hillsboro, Oregon, delivers thorough substance use recovery programs for adults and young adults. Their services include intensive outpatient care, general outpatient support, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. CODA Inc focuses on methods like 12-step facilitation, anger management, and brief intervention strategies. The center offers customized programs designed for adult men, adult women, and individuals affected by intimate partner or domestic violence, ensuring personalized attention. CODA Inc is dedicated to providing high-quality rehabilitation and support for individuals overcoming substance use challenges.

COPE Community Services Inc, located in Tucson, AZ, specializes in treating adults facing substance use issues alongside severe mental health disorders and offers assistance to children dealing with significant emotional challenges. The center features a range of programs, including intensive outpatient, standard outpatient, and treatment options using methadone, buprenorphine, or naltrexone. Through methods such as anger management, cognitive behavioral therapy, and contingency management, this center addresses the needs of clients who have encountered trauma as well as those with combined mental health and addiction challenges. COPE Community Services Inc provides effective care and resources for adults and young adults of all genders in their journey toward recovery.

CODA Inc, located in Portland, Oregon, specializes in outpatient services for substance use disorders, offering treatments involving methadone, buprenorphine, or naltrexone alongside standard outpatient support. The center emphasizes therapeutic approaches such as cognitive behavioral therapy, anger management, and brief interventions, ensuring that it meets the needs of adult men and women, including those who have faced traumatic experiences. Catering to a diverse clientele of all genders, CODA Inc provides personalized care designed to support unique recovery journeys. With a dedication to delivering high-quality treatment and an array of tailored programs, this center stands as a source of hope for individuals pursuing effective and empathetic addiction recovery solutions.

COPE Community Services Inc, located in Tucson, Arizona, specializes in addressing substance use issues alongside co-existing mental health concerns for both adults and children. The center offers a range of services, including intensive outpatient and outpatient treatment options, such as methadone and buprenorphine therapy. They focus on various therapeutic methods, including anger management and cognitive behavioral therapy, applying the Matrix Model for personalized support. Special programs are available for individuals impacted by intimate partner violence, trauma, and dual diagnosis. COPE Community Services Inc is dedicated to providing thorough and effective care for individuals of all genders, aiding them in their recovery journey.

In Cranston, RI, CODAC Behavioral Healthcare provides extensive addiction recovery support. Their expertise covers detoxification, managing substance dependency, and concurrent treatment for adults with serious mental health issues or children experiencing emotional distress. They offer various treatment levels, such as intensive outpatient services, standard outpatient care, and outpatient detoxification, employing proven methods like cognitive behavioral therapy and motivational incentives to foster sustained healing. Personalized programs are designed for adult men, adult women, and young adults, accommodating different age demographics and genders. CODAC Behavioral Healthcare distinguishes itself with its all-encompassing and personalized approach to recovery, serving adults and seniors.

CODAC Behavioral Healthcare in Providence, RI, delivers a full spectrum of addiction recovery solutions. This facility provides detox services, addiction treatment, and tailored support for those facing concurrent substance use and significant mental health challenges. Options for care encompass intensive outpatient, outpatient, and outpatient detox programs. CODAC utilizes proven therapeutic methods, including brief intervention, cognitive behavioral therapy, and contingency management/motivational incentives. Specific programs are offered for adult men, adult women, and women who are pregnant or have recently given birth. CODAC Behavioral Healthcare, serving adults and seniors of all genders, is dedicated to providing excellent, personalized treatment for individuals striving for sobriety.

COPE Community Services Inc, located in Tucson, AZ, provides a variety of research-backed therapies for individuals facing substance abuse issues as well as co-existing mental health conditions, applicable to both adults and youth. The facility offers several treatment modalities, including intensive outpatient services, outpatient care, and medication-assisted therapies. Emphasizing anger management, cognitive behavioral approaches, and motivational strategies, the programs are designed to assist those with trauma backgrounds and dual diagnoses. This center is committed to offering personalized, compassionate care to individuals of all genders, supporting them as they work towards recovery.

CODAC Behavioral Healthcare, situated in Newport, RI, provides a complete spectrum of recovery assistance for adults and older individuals. Their expertise lies in detoxifying, treating substance abuse, and managing co-occurring mental health conditions. The center offers intensive outpatient care, standard outpatient services, and specialized outpatient detox programs. Employing proven methods like cognitive behavioral therapy and contingency management, CODAC supports adult men, women, and young adults. Committed to high-quality care and individualized plans, this establishment focuses on guiding people toward healing from addiction and dual diagnosis challenges.

COMCARE of Sedgwick County in Wichita, KS, is a facility dedicated to aiding individuals facing challenges with addiction and accompanying mental health issues. They offer structured outpatient programs, general outpatient services, and medication-supported therapies including methadone, buprenorphine, or naltrexone. The center employs proven therapeutic methods, such as cognitive behavioral therapy and contingency management, to assist patients in their journey toward wellness. COMCARE delivers thorough support for adults and young adults, with distinct programs designed for adult men, adult women, and those with dual diagnoses. Discover effective and individualized support at this premier recovery establishment.

COPE Community Services Inc, located in Green Valley, AZ, provides an extensive selection of substance use treatment options for both adults and children/adolescents dealing with simultaneous mental health issues. The center offers intensive outpatient programs and outpatient services, which include treatments utilizing methadone/buprenorphine or naltrexone. Emphasizing evidence-based methods such as cognitive behavioral therapy and the Matrix Model, this facility is dedicated to tackling concerns such as intimate partner violence, trauma, and co-occurring disorders. COPE Community Services Inc serves a diverse clientele, ensuring high-quality care and personalized treatment plans to facilitate recovery and promote overall well-being.

COPE Community Services Inc, located in Tucson, AZ, provides focused treatment for substance use and co-occurring mental health disorders for both adults and children. Their outpatient and intensive outpatient programs implement proven methods such as cognitive behavioral therapy and anger management techniques. This center is dedicated to offering customized services for individuals with a history of trauma and those facing concurrent mental health and substance use challenges. Catering to both male and female adults as well as young adults, COPE is recognized for its extensive range of treatment options and commitment to high-quality care. Clients have access to outpatient methadone/buprenorphine or naltrexone therapies, supporting a comprehensive recovery process.

Situated in Seaside, OR, CODA Inc provides outpatient treatment services for substance use aimed at both adult men and women, along with young adults. This center specializes in managing anger, conducting brief interventions, and employing cognitive behavioral therapy, offering personalized support for those who have faced trauma. CODA Inc features dedicated programs for adult men, adult women, and survivors of trauma, ensuring that each individual receives customized care. By providing outpatient options such as methadone/buprenorphine or naltrexone therapies, the center emphasizes high-quality care and proven methods to assist clients in achieving enduring recovery.

Situated in East Providence, RI, CODAC Behavioral Healthcare delivers a wide array of evidence-supported treatment options for adults and young adults facing challenges related to substance use and concurrent mental health issues. The facility specializes in intensive outpatient care, outpatient services, and outpatient detox programs, employing methods like brief intervention, cognitive behavioral therapy, and motivational incentives. With tailored programs for adult men, adult women, and young adults, CODAC Behavioral Healthcare accommodates a variety of populations. Their dedication to providing high-quality care for individuals of all genders, including seniors, positions this center as a crucial asset for those in search of effective and customized addiction treatment solutions.

CODAC Behavioral Healthcare in Pawtucket, RI, delivers a full spectrum of addiction recovery support. Their offerings encompass detox and comprehensive substance use therapy. Patients can access structured day programs, general outpatient care, and detoxification outside of a residential setting, all adapted to personal circumstances. CODAC employs proven methods like brief intervention, cognitive behavioral therapy, and motivational incentives. They serve adult men, adult women, and young adults, as well as older adults, providing specialized care for all genders to guide them toward lasting sobriety.

CODAC Behavioral Healthcare II, located in Saunderstown, RI, delivers extensive addiction treatment services for both adults and children facing concurrent mental health issues. Their offerings encompass detox programs, substance abuse treatment, and therapy addressing significant emotional challenges. Emphasizing cognitive behavioral therapy and motivational incentives, the center provides both intensive outpatient and outpatient care for adult men, women, and young adults. Catering to all genders and elderly clients, this facility adopts a customized approach to meet the unique needs of each individual. CODAC Behavioral Healthcare II is recognized for its high-quality care and specialized services, positioning it as a premier option for individuals seeking effective rehabilitation solutions.

Situated in Montclair, New Jersey, the COPE Center offers tailored recovery programs for adults and young adults confronting addiction and associated mental health challenges. Their services include intensive outpatient, outpatient, and medication-assisted treatment (methadone/buprenorphine or naltrexone). The center employs proven therapeutic methods, including cognitive behavioral therapy and anger management. COPE Center supports adult men and women, as well as individuals with a history of trauma. Emphasizing personalized attention and thorough assistance, the COPE Center delivers effective care for those aiming to conquer substance dependence and enhance their mental well-being.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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