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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Care Plus NJ Inc
Paramus, NJ

Care Plus NJ Inc. in Paramus, NJ, provides extensive therapeutic options for adults and young people dealing with addiction and mental health concerns. Their offerings include structured outpatient and intensive outpatient care, encompassing services like detox, cognitive behavioral therapy, and motivation-based interventions. They also offer targeted support for teenagers, members of the LGBTQ community, and individuals with coexisting conditions. Committed to high standards of care, Care Plus NJ Inc. serves adults and elderly individuals across the gender spectrum, delivering personalized assistance for each person's path to wellness.

Care Resource Comm Health Ctrs

Care Resource Comm Health Ctrs located in Miami, FL, provides outpatient services for substance use treatment catering to both adults and children dealing with concurrent serious mental health conditions. The center features dedicated programs for trauma-affected individuals, those living with HIV/AIDS, and persons facing dual diagnoses, ensuring a holistic approach to recovery. Treatment options encompass anger management, brief interventions, and cognitive behavioral therapy. Customized outpatient services with methadone, buprenorphine, or naltrexone are offered. This facility is committed to delivering superior care to male and female clients pursuing recovery from substance use issues alongside mental health concerns.

Care Resource Comm Health Ctrs

Care Resource Comm Health Ctrs in Fort Lauderdale, FL, provides outpatient care for adults and children battling substance misuse and co-occurring mental health issues. Their comprehensive approach includes medication-assisted treatment with methadone, buprenorphine, or naltrexone, complemented by cognitive behavioral therapy and anger management strategies. The center offers specialized support for individuals with a history of trauma, those living with HIV/AIDS, and people experiencing dual diagnoses of substance use and mental health disorders. Services are individualized for adults and young adults, accommodating both male and female clients. Care Resource Comm Health Ctrs is dedicated to delivering excellent care to support clients in their path to healing and wellness.

Care STL Health
Saint Louis, MO

Care STL Health, located in Saint Louis, MO, stands out as a leading rehabilitation center that provides a variety of treatment options for individuals dealing with substance use disorders and concurrent mental health issues, applicable to both adults and children. The facility offers outpatient services such as methadone/buprenorphine therapies and cognitive behavioral therapy, aimed at creating personalized recovery plans. Special initiatives are in place for active duty service members, teenagers, and adult males, with accessible services for adults and seniors of all gender identities. The center prioritizes anger management, brief interventions, and customized care, ensuring that individuals receive high-quality support in their path towards recovery and well-being.

Carestl Health Pope
Saint Louis, MO

At Carestl Health Pope in Saint Louis, MO, we provide extensive outpatient support for individuals, spanning all age groups, who are navigating substance use challenges, particularly when co-occurring serious mental health conditions or emotional disturbances are present. Our services are structured to address the distinct requirements of active duty military members, teenagers, and adult men, with personalized treatment strategies designed for every person. Emphasizing techniques such as anger management, brief intervention strategies, and cognitive behavioral therapy, this center is committed to delivering superior care to adults and older adults, regardless of gender. Carestl Health Pope is steadfast in its mission to assist individuals in their pursuit of lasting recovery, whether through outpatient methadone/buprenorphine services or general outpatient care.

Carestl Health Riverview

Carestl Health Riverview, located in Saint Louis, MO, offers extensive outpatient services for individuals of all ages grappling with substance use and dual diagnoses. The facility is equipped to address the unique needs of various groups, including military personnel, teenagers, and adult men, through tailored treatment plans. Utilizing a variety of therapeutic modalities such as anger management techniques, cognitive behavioral therapy, and short-term counseling, Carestl Health Riverview is committed to providing individualized support. Additionally, they provide outpatient medication-assisted treatment using methadone, buprenorphine, or naltrexone, alongside standard outpatient care for adult men and women. Their mission is to deliver high-quality, evidence-based care to adults and older adults, regardless of gender, with the ultimate goal of fostering sustained recovery.

Carestlhealth
Saint Louis, MO

Carestlhealth, situated in Saint Louis, MO, stands out as a premier rehabilitation center that provides outpatient services for adults struggling with substance use disorders and co-occurring severe mental health issues, as well as emotional challenges in children. The center features targeted programs for active military members, teens, and adult males. Carestlhealth employs a variety of evidence-based methods such as anger management, brief interventions, and cognitive behavioral therapy. Catering to adults and seniors of any gender, the facility is focused on delivering exceptional care that is specifically designed to address the distinct needs of each patient. If you are in search of thorough and effective addiction recovery solutions, Carestlhealth is dedicated to assisting you on your path to healing.

Carilion New River Valley Medical Ctr

Carilion New River Valley Medical Ctr, situated in Christiansburg, VA, delivers extensive recovery programs for both young and adult individuals struggling with addiction and accompanying mental health challenges. The facility offers inpatient detox and care, emphasizing strategies like brief intervention, motivational interviewing, and counseling for substance use issues. They also feature distinct services for men, women, and survivors of domestic abuse. Carilion New River Valley Medical Ctr provides customized support for adults, older adults, and young adults across the gender spectrum, promoting individual healing and wellness.

Caring Hands Recovery LLC

Caring Hands Recovery LLC, situated in Corona, CA, provides an extensive array of rehabilitation services. The center specializes in detoxification, treatment for substance use disorders, and addressing co-occurring mental health conditions. It offers residential detox programs, round-the-clock care, and short-term residential options. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, the facility customizes its services to fit each individual's recovery needs. Catering to adults and young adults of various genders, Caring Hands Recovery LLC is recognized for its dedication to delivering high-quality care and personalized treatment plans.

CARE Center Inc
Washington, PA

The CARE Center Inc, situated in Washington, PA, delivers an extensive array of services for substance use treatment. This center focuses on individuals grappling with co-occurring substance use issues and significant mental health conditions in adults, as well as serious emotional challenges in children. Treatment options available encompass intensive outpatient services, outpatient programs, and day treatment. The CARE Center Inc emphasizes personalized care, utilizing methods such as 12-step support, anger management strategies, and concise interventions. Specialized programs are available for adolescents, adult males, and adult females, ensuring that the facility accommodates both adults and seniors of all genders, while maintaining a commitment to high-quality care that meets individual requirements.

Caring Center of Wichita

Situated in Wichita, Kansas, the Caring Center of Wichita delivers focused care for substance abuse, concurrent mental health issues, and emotional challenges in children. This center offers both intensive outpatient and general outpatient services, featuring treatments with methadone and buprenorphine. Their methodology includes anger management techniques, brief intervention strategies, and cognitive behavioral therapy (CBT). Specialized programs are designed for teenagers, adult males, and those facing dual diagnosis issues. Catering to adults and senior clients of every gender, the center emphasizes high-quality care and personalized treatment strategies to foster enduring recovery.

CarePoint Health/Christ Hospital

CarePoint Health/Christ Hospital, located in Jersey City, NJ, provides specialized services for adults dealing with substance use disorders and co-occurring mental health challenges, as well as support for children facing emotional issues. The facility offers both intensive outpatient and outpatient treatment, which includes options like methadone and buprenorphine therapies. A variety of evidence-based practices are employed, such as cognitive behavioral therapy, anger management, and motivational incentives. The center features distinctive programs designed for adult women, including those who are pregnant or in the postpartum stage, and caters to both male and female adults, as well as children and adolescents. CarePoint Health/Christ Hospital is dedicated to offering high-quality care that meets the unique needs of each client, positioning itself as an essential resource for individuals seeking thorough addiction recovery solutions.

Caritas Treatment and Wellness Center

Caritas Treatment and Wellness Center in Cleveland, OH, provides comprehensive addiction recovery services, including detox and specialized treatment programs like intensive outpatient, standard outpatient, and medication-assisted options (methadone, buprenorphine, naltrexone). Their therapeutic framework incorporates evidence-based practices such as 12-step integration, anger management, and brief intervention strategies. The center also offers tailored support for active military personnel, adult men, and adult women, serving adults and young adults of all genders. Emphasizing personalized care and a commitment to effective treatment, Caritas Treatment and Wellness Center is a recognized resource for individuals pursuing lasting sobriety.

Caring Choices of Alexandria

Caring Choices of Alexandria, situated in Alexandria, LA, specializes in thorough treatment for adults struggling with substance use, including those who also face significant mental health challenges. The center features both intensive outpatient and standard outpatient programs, along with options for outpatient treatment using methadone, buprenorphine, or naltrexone. The facility employs tailored methods, including 12-step programs, anger management, and brief intervention strategies, specifically targeting the needs of active duty military members, as well as adult men and women. Catering to both men and women of various ages, Caring Choices of Alexandria is dedicated to providing exceptional care and support for those on their journey to recovery from addiction.

CARE Center
Freeport, NY

Situated in Freeport, NY, the CARE Center delivers extensive outpatient rehabilitation services aimed at addressing substance use disorders and concurrent mental health issues for both adults and minors. The facility features dedicated programs designed for teenagers, adult males, and females, offering personalized treatment plans that utilize proven strategies such as anger management, cognitive behavioral therapy, and the Matrix Model. Among its services, the center provides outpatient treatment with methadone, buprenorphine, or naltrexone, alongside typical outpatient support. Catering to both men and women, the CARE Center emphasizes high-quality care to assist individuals in their recovery journeys.

Caring Choices of Leesville

Caring Choices of Leesville, situated in Leesville, LA, delivers an extensive array of substance abuse treatment options designed for both adults and young adults grappling with co-occurring mental health disorders. The center features various treatment approaches, including intensive outpatient, outpatient, and outpatient services utilizing methadone, buprenorphine, or naltrexone. With an emphasis on anger management, brief intervention techniques, and cognitive behavioral therapy, the facility caters to adult males, females, and active duty military members. By providing tailored services for both genders, Caring Choices of Leesville prioritizes effective treatment for individuals pursuing recovery from addiction and mental health conditions.

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Waynesburg, PA

Situated in Waynesburg, PA, CARE Center Inc delivers an extensive array of services for individuals dealing with substance use issues, including those with concurrent mental health conditions. The facility provides intensive outpatient services, outpatient treatment, as well as targeted programs utilizing methadone, buprenorphine, or naltrexone. Emphasizing techniques such as 12-step support, anger management, and brief interventions, CARE Center Inc accommodates both adolescents and adults, regardless of gender. This center focuses on personalized care, making sure that everyone seeking effective addiction recovery is supported in a friendly and nurturing setting.

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New York, NY

CARES, situated in New York, NY, stands as a leading rehabilitation center providing outpatient services for individuals grappling with substance use disorders and co-occurring mental health concerns. They also offer support for emotional disturbances in children. The facility excels in specialized areas such as anger management, brief intervention strategies, and cognitive behavioral therapy. CARES is dedicated to delivering personalized care through tailored programs designed for adolescents, survivors of domestic abuse, and those who have endured sexual assault, serving both male and female clients across all age groups. By employing evidence-based methodologies and emphasizing customized treatment paths, CARES ensures a high standard of care for everyone on their journey toward recovery and well-being.

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New York, NY

Based in New York, NY, CARES stands as a premier facility dedicated to outpatient rehabilitation. They provide specialized care for individuals of all ages, addressing substance use disorders and co-occurring mental health conditions. Their expertise encompasses anger management, brief intervention strategies, and cognitive behavioral therapy, all delivered with a personalized approach. CARES distinguishes itself with distinctive programs designed for adolescents, and survivors of intimate partner violence, domestic abuse, and sexual assault. Committed to inclusivity, they welcome adults, children, adolescents, and young adults across all gender identities. For those pursuing holistic recovery, focusing on mental and emotional wellness alongside addiction treatment, CARES offers a guiding hand.

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McAlester, OK

Situated in McAlester, OK, Carl Albert is a highly regarded rehabilitation center that provides outpatient solutions for substance abuse to both adults and children grappling with concurrent severe mental health disorders. The center features tailored programs designed for teenagers, adult men, and women within a nurturing and secure setting. The therapeutic methods employed encompass anger management, cognitive behavioral therapy, and short-term interventions. Carl Albert also serves adults and elderly clients with outpatient services including methadone/buprenorphine or naltrexone treatment options. Committed to delivering high-quality care, this center focuses on personalized treatment strategies aimed at enabling individuals to attain sustainable recovery.

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Idabel, OK

Carl Albert in Idabel, Oklahoma, is a premier facility providing outpatient services for adults struggling with addiction and co-occurring mental health conditions, alongside support for children experiencing emotional difficulties. This center tailors its approach with distinct programs for teenagers, adult males, and adult females, accommodating individuals across the lifespan, from young adults to seniors. Through specialized interventions such as anger management, brief therapy, and cognitive behavioral therapy, Carl Albert is dedicated to delivering personalized treatment. The center also offers medication-assisted treatment options, including methadone, buprenorphine, or naltrexone, ensuring comprehensive recovery support for all clients.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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