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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Carle BroMenn Medical Center

Carle BroMenn Medical Center, located in Normal, IL, offers a wide array of services for addiction recovery, including detox and treatment for substance use disorders. This center features hospital-based inpatient detox, around-the-clock inpatient support, and intensive outpatient options. Utilizing proven methods like cognitive behavioral therapy and anger management, the facility is committed to evidence-based practices. It also provides specialized services for active duty military personnel and tailored programs for adult men and women, accommodating individuals across all age groups and genders. Renowned for its exceptional care and flexible treatment strategies, Carle BroMenn Medical Center is a reliable option for those pursuing effective recovery in a nurturing setting.

Caron of Florida
Delray Beach, FL

Caron of Florida, situated in Delray Beach, FL, delivers a wide range of addiction recovery services. This center specializes in detox and substance use therapy, offering intensive outpatient, outpatient, and day treatment options. Utilizing distinct methods such as 12-step support, anger management, and brief interventions, it serves adults and young adults across all genders. The facility also features specialized programs for individuals with dual diagnoses and older adults, distinguishing itself from others. Committed to personalized care, Caron of Florida stands out as an excellent option for individuals pursuing compassionate and effective addiction recovery.

Caron Treatment Centers
Wernersville, PA

Caron Treatment Centers, situated in Wernersville, PA, delivers a wide array of services for addiction recovery. The center features outpatient care, day treatment, partial hospitalization, and residential detox programs. Emphasizing 12-step methods, cognitive behavioral therapy, and motivational strategies, the facility supports both adult men and women, including individuals affected by intimate partner violence. Catering to both adults and younger populations, Caron Treatment Centers provides customized treatment plans designed to address the distinct requirements of each client. With a strong focus on quality and evidence-based approaches, this center is a reliable option for those in need of effective and empathetic addiction recovery solutions.

Caron Treatment Centers

Situated in Reading, PA, Caron Treatment Centers delivers extensive treatment options for substance use disorders, catering to both adults and young individuals. Emphasizing various levels of outpatient care, including intensive and regular outpatient programs, this center offers targeted therapies such as 12-step support, anger management, and cognitive behavioral techniques. Specialized tracks are available for adolescents, individuals who have experienced trauma, and those facing dual diagnoses of mental health and substance use issues. Caron Treatment Centers is dedicated to providing top-notch care for all genders, making it a key provider for those in need of tailored rehabilitation solutions.

Caron Treatment Centers
Plymouth Meeting, PA

Caron Treatment Centers, situated in Plymouth Meeting, PA, provides an all-encompassing approach to treating adolescent substance use issues. The center features targeted programs for individuals who have faced trauma and those dealing with concurrent mental health and substance abuse challenges. Treatment options include intensive, outpatient, and standard outpatient care. By employing evidence-supported methods such as 12-step support, anger management, and cognitive behavioral therapy, Caron Treatment Centers offers customized care for both young men and women. The facility is distinguished by its dedication to delivering high-quality treatment and personalized plans that cater to the specific requirements of each person on their recovery journey.

Carondelet Saint Josephs Hospital

Carondelet Saint Josephs Hospital in Tucson, AZ, delivers an extensive range of rehabilitation options for adults and adolescents facing substance use problems alongside mental health challenges. The center features inpatient detoxification services and various treatment programs that include cognitive behavioral therapy, anger management strategies, and short-term interventions customized to fit individual requirements. Emphasizing tailored care, the facility serves both male and female patients. What sets this center apart is its dedicated approach to addressing severe emotional issues in children and significant mental health disorders in adults. If you are looking for effective, gender-focused addiction treatment for yourself or someone close to you, Carondelet Saint Josephs Hospital is a trusted option for achieving recovery.

Carolina Center for Behavioral Health

Situated in Greer, SC, the Carolina Center for Behavioral Health specializes in extensive addiction recovery services for both adults and young individuals grappling with substance use challenges and accompanying mental health conditions. The facility features hospital-based inpatient detoxification and therapeutic programs tailored for adult males, adult females, and clients facing dual diagnoses. Their treatment modalities encompass 12-step principles, brief intervention methods, and cognitive behavioral strategies. Emphasizing personalized care to meet diverse needs, this center is committed to supporting individuals in attaining sustainable recovery and enhanced mental health.

Carolina Recovery Solutions

Carolina Recovery Solutions, located in Weaverville, NC, offers a wide range of services for those struggling with addiction. The facility specializes in detoxification and various treatment options, including transitional housing and sober living environments. Patients have access to intensive outpatient programs, outpatient day treatment, and partial hospitalization, allowing for personalized care that meets their specific needs. The center incorporates specialized methods like 12-step programs, anger management sessions, and brief therapeutic interventions into their treatment strategies. Catering to active duty military members as well as adult men and women, Carolina Recovery Solutions is dedicated to providing high-quality, individualized care for all adults and young adults on their path to recovery.

Carolina Specialty Care PA

Carolina Specialty Care PA, located in Statesville, NC, provides extensive outpatient treatment for substance use disorders targeting adults and seniors. This center features specialized programs designed to meet the unique needs of each client, offering treatment options including outpatient methadone/buprenorphine or naltrexone, alongside standard outpatient services. Emphasizing a holistic and personalized approach, the facility is committed to facilitating effective recovery. Carolina Specialty Care PA is open to clients of all genders, fostering an inclusive and supportive atmosphere. For those in search of exceptional addiction treatment that combines compassion with tailored care, this center is dedicated to guiding you on your path to recovery.

Carolina Family Health Centers Inc

Situated in Tarboro, NC, Carolina Family Health Centers Inc delivers a wide array of outpatient services designed for adults dealing with substance use issues and co-occurring mental health conditions, as well as addressing emotional challenges in children. The center implements various evidence-based treatment modalities such as cognitive behavioral therapy, motivational interviewing, and brief intervention strategies. Notably, it offers specialized programs for pregnant or postpartum women, clients affected by HIV/AIDS, and those involved in the criminal justice system. By emphasizing gender-sensitive care for both men and women, this facility guarantees high-quality treatment for adults and youth in recovery. Carolina Family Health Centers Inc also specializes in outpatient treatment options using methadone, buprenorphine, or naltrexone, committing to deliver effective and compassionate support for individuals seeking assistance.

Carolina Performance

Carolina Performance, situated in Raleigh, NC, stands as a premier center for recovery, delivering outpatient substance abuse treatment and specialized services for individuals facing dual diagnoses of substance use and significant mental health challenges. The facility also offers support for emotional disturbances in young individuals. Their approach includes outpatient medication management with methadone, buprenorphine, or naltrexone, incorporating proven therapeutic methods like 12-step facilitation, anger management training, and brief intervention strategies. Carolina Performance designs its programs to meet the unique needs of adolescents, adult men, and women, serving adults and older adults across all gender identities. Patients can expect exceptional care and custom-made treatment paths, providing complete assistance throughout their recovery process.

Carroll County Youth Service Bureau

The Carroll County Youth Service Bureau, situated in Westminster, MD, specializes in outpatient treatment for substance use issues among both adults and children, addressing co-existing mental health challenges. This center offers targeted programs for active duty military personnel, teenagers, and adult males, employing evidence-based practices such as cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders. The facility also provides tailored outpatient options that may involve treatments like methadone/buprenorphine or naltrexone. Catering to adults and seniors of diverse backgrounds, the center develops customized treatment plans for every individual, promoting a nurturing atmosphere for recovery and healing.

Carolina Family Health Centers

Situated in Elm City, NC, Carolina Family Health Centers is a distinguished establishment that offers outpatient treatment for substance use issues, catering to both adults and children/adolescents facing serious emotional challenges. Their tailored programs address individuals dealing with simultaneous mental health and substance use disorders, utilizing evidence-based methods such as cognitive behavioral therapy and motivational interviewing. The facility also administers outpatient treatment options involving methadone, buprenorphine, or naltrexone. Key services include programs designed for pregnant or postpartum women, individuals living with HIV/AIDS, and those involved with the criminal justice system. With a commitment to providing exceptional care, Carolina Family Health Centers serves both men and women seeking extensive rehabilitation support.

Carl E Dahl House at Evergreen Grove

Located in Gardner, MA, the Carl E Dahl House at Evergreen Grove offers long-term residential substance use treatment for adult men with co-occurring mental health disorders. This facility specializes in providing 24-hour care using evidence-based approaches such as 12-step facilitation, anger management, and brief intervention. Tailored programs for adult men, individuals with co-occurring mental health and substance use issues, and clients of various age groups including adults, seniors, and young adults are available. With a focus on quality care and individualized treatment, this center is a trusted choice for those seeking comprehensive rehabilitation services.

Carle Addiction Recovery Center

Situated in Champaign, IL, the Carle Addiction Recovery Center delivers extensive treatment solutions for both adults and teenagers dealing with addiction. This facility is equipped to address the needs of those facing simultaneous challenges related to substance abuse and significant mental health conditions. Available treatments encompass intensive outpatient schedules, detox services on an outpatient basis, and cognitive behavioral therapy. Tailored programs are available for active duty military members, adult males, and youth. Emphasizing anger management and short intervention strategies, this center services both men and women. The Carle Addiction Recovery Center is dedicated to providing exceptional support for individuals on their journey toward overcoming substance use disorders and co-occurring conditions.

Carlsbad LifeHouse Inc

Carlsbad LifeHouse Inc. located in Carlsbad, NM, provides extensive support for individuals battling addiction. Their offerings encompass detox, partial hospitalization, and extended stay residential recovery. Employing specific methodologies like 12-step integration and emotional regulation, the center serves adult men and women, including those affected by domestic abuse. Through transitional housing and sober living arrangements, this establishment aids individuals in their pursuit of sobriety. Emphasizing high-quality support and customized recovery strategies, Carlsbad LifeHouse Inc. is committed to assisting adults and adolescents in attaining sustained freedom from addiction.

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Holdenville, OK

Situated in Holdenville, OK, Carl Albert provides an extensive selection of outpatient treatment options for substance use, specifically designed for individuals facing significant mental health challenges concurrently. This center delivers focused care for both adults and children, utilizing methods such as anger management, cognitive behavioral therapy, and brief intervention strategies. Emphasizing customized treatment approaches, Carl Albert serves adolescents, as well as men and women in adulthood. The facility accommodates individuals of all genders, including seniors, with its outpatient programs for methadone/buprenorphine or naltrexone and standard outpatient services aimed at fostering recovery from addiction and mental health issues.

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Stigler, OK

Carl Albert, situated in Stigler, Oklahoma, is a leading recovery facility dedicated to providing expert care for adults struggling with substance abuse and co-occurring mental health issues, as well as children facing emotional challenges. The center offers a variety of outpatient treatments such as methadone/buprenorphine therapy, cognitive behavioral therapy, anger resolution, and short-term counseling. Recognizing the unique needs of different age groups and genders, Carl Albert features custom programs for teenagers, adult men, and women. Open to adults and older adults across all gender identities, the facility is committed to delivering high-quality, research-backed methods to aid individuals in their path to healing.

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Situated in Carson City, NV, Carson City Community Counseling Ctr delivers an array of specialized programs designed for those in need of substance abuse rehabilitation and transitional housing assistance. This center features intensive outpatient services, outpatient treatment using methadone, buprenorphine, or naltrexone, along with various methodologies including 12-step support and anger management strategies. Emphasizing the treatment of co-occurring substance use disorders alongside significant mental health challenges, the center serves both adults and children, with dedicated programs for active military members, teenagers, and men. The facility provides comprehensive, evidence-based care for individuals of all ages and genders, ensuring that each person receives personalized treatment that meets their unique requirements.

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The Carson City Community Counseling Center, situated in Carson City, NV, provides extensive support for individuals struggling with substance use. They offer a range of treatment durations, including extended, brief, and round-the-clock residential options, serving both adults and young adults. Their therapeutic specialties encompass 12-step program integration, anger management techniques, and short-term intervention strategies, all designed to offer personalized care for adult men and women. Additionally, specialized services are available for active military members. This center is committed to creating individualized treatment plans to aid all clients, regardless of gender, in achieving lasting recovery and improved well-being.

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Smithfield, NC

Situated in Smithfield, NC, the Carter Clinic delivers extensive outpatient treatment for individuals facing substance use issues, including adults and children who also have concurrent mental health challenges. This center features a variety of specialized programs that serve active duty military members, teens, and adult males. Emphasizing cognitive behavioral therapy and counseling for substance use disorders, the clinic also offers telehealth services to enhance accessibility. Aiming to accommodate both men and women, the facility develops personalized treatment plans for every client. The Carter Clinic remains committed to offering top-notch, evidence-driven care to aid individuals in their recovery process.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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