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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Chase Brexton Healthcare

Chase Brexton Healthcare, located in Baltimore, MD, provides targeted substance use treatment for adults facing significant mental health challenges and children dealing with major emotional issues. Their comprehensive outpatient programs utilize proven methods including 12-step facilitation, cognitive behavioral therapy, and short-term interventions. This center also offers outpatient treatments with methadone, buprenorphine, or naltrexone. Their specific programs are designed for adult males, females, and individuals who have suffered from intimate partner violence. By prioritizing exceptional care, Chase Brexton Healthcare supports adults and adolescents of all genders within a welcoming and inclusive setting.

Chateau Recovery

Chateau Recovery, situated in Midway, UT, provides extensive treatment for substance use disorders aimed at both adults and young adults. Offering a range of options, including long-term residential care, outpatient services, and day programs, the center employs methods such as 12-step facilitation, anger management, and brief intervention strategies. It features dedicated programs for active duty military members as well as separate tracks for adult men and women. Chateau Recovery is committed to maintaining a supportive atmosphere while delivering exceptional care to all clients. If you're interested in individualized addiction recovery options with various program structures and tailored paths, this facility may be a perfect fit for your healing process.

Chautauqua County Dept Mental Hygiene

Situated in Dunkirk, NY, the Chautauqua County Dept Mental Hygiene delivers extensive treatment for substance use disorders affecting both adults and children who are also dealing with significant mental health issues. The center specializes in outpatient care and offers therapies such as methadone/buprenorphine and naltrexone. Emphasizing techniques like anger management and cognitive behavioral therapy, the facility serves a diverse clientele, including active duty military personnel, adolescents, and adult males. Catering to adults and seniors of all genders, this center is dedicated to providing personalized care and assistance for individuals striving to address their addiction and mental health difficulties.

Chartiers Community MH and Retardatio

Situated in Bridgeville, PA, Chartiers Community MH and Retardatio specializes in treating adults dealing with substance use issues alongside significant mental health disorders, as well as children facing serious emotional challenges. The center offers various treatment options, including intensive outpatient programs, standard outpatient services, and medications such as methadone, buprenorphine, or naltrexone for those in need. Through the application of methods like cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders, the facility tailors its services to meet the unique needs of each client. The programs are designed to cater to both adults and youth of all genders, emphasizing a commitment to high-quality care through individualized treatment strategies.

Chase Brexton Healthcare

Chase Brexton Healthcare, situated in Glen Burnie, MD, delivers a wide-ranging approach to treating substance use disorders among adults with concurrent severe mental health challenges. This center features a variety of programs including intensive outpatient services, outpatient support, and specific treatments using methadone, buprenorphine, or naltrexone. Emphasizing a combination of 12-step support, cognitive behavioral therapy, and targeted interventions, the facility customizes its offerings to address individual requirements. Specialized programs are available for adult men and women, as well as those who have faced domestic or intimate partner violence. Catering to adults and young adults across all gender identities, Chase Brexton Healthcare is dedicated to providing exceptional care and assistance for those on their journey to recovery.

Chautauqua County Department of

Situated in Jamestown, NY, the Chautauqua County Department of Rehabilitation Center specializes in outpatient treatment for adults dealing with substance use issues alongside serious mental health conditions. This center offers tailored support for those experiencing emotional challenges, incorporating services like cognitive behavioral therapy, anger management, and brief intervention. Additionally, it features unique programs designed for active military members, teenagers, and adult males. The facility is committed to providing high-quality care to adults and seniors of all genders, utilizing various formats such as outpatient services, methadone/buprenorphine, or naltrexone treatments. For those in need of extensive addiction support within a nurturing environment, this center is focused on guiding you through your recovery journey.

Chemical Addictions Recovery Effort

Situated in Marianna, FL, Chemical Addictions Recovery Effort specializes in providing extensive treatment for adults facing substance use challenges, particularly those with concurrent severe mental health disorders, as well as children grappling with significant emotional issues. The center offers a range of services, including intensive outpatient, outpatient, and medications like methadone, buprenorphine, or naltrexone. It features specialized programs designed for various demographics, including adolescents, women, and individuals involved in the criminal justice system. By employing methods like anger management, cognitive behavioral therapy, and brief interventions, the facility ensures that care is personalized. Accommodating both men and women, this center emphasizes quality care focused on individualized treatment plans aimed at achieving enduring recovery.

Chemical Addictions Recovery Effort

Situated in Alford, FL, the Chemical Addictions Recovery Effort provides an extensive array of services for substance use treatment as well as transitional housing for adult women and seniors. The center focuses on addressing co-occurring substance use disorders alongside significant mental health challenges, employing effective methods like cognitive behavioral therapy and the 12-step framework. Its long-term and 24-hour residential programs are designed to meet the specific needs of clients who have faced intimate partner or domestic violence. Committed to delivering high-quality care, this facility offers tailored programs for active military members, adult females, and those coping with substance use and mental health difficulties.

Cherokee Health Systems

Cherokee Health Systems, located in Chattanooga, TN, specializes in outpatient care for individuals facing substance use challenges alongside mental health disorders, catering to both adults and children. The center utilizes various treatment modalities, including anger management strategies, cognitive behavioral therapy, and short intervention techniques. Customized programs are designed for those dealing with dual diagnoses of mental health issues and substance dependency. With an emphasis on serving adults and elderly individuals of all genders, Cherokee Health Systems delivers exceptional care through outpatient services, including methadone/buprenorphine or naltrexone treatment. This facility is committed to providing a nurturing atmosphere for those seeking extensive support on their recovery journey.

Cherokee Health Systems

Cherokee Health Systems, located in Alcoa, TN, specializes in outpatient services for individuals dealing with substance use issues and concurrent mental health challenges, serving both adults and children. The center employs a variety of evidence-supported methodologies, such as cognitive behavioral therapy, anger management, and brief intervention techniques. Prioritizing high-quality care, Cherokee Health Systems focuses on individuals with dual diagnoses, offering outpatient treatments like methadone/buprenorphine and naltrexone. Their programs are designed to meet the needs of adults and seniors of all genders. If you or someone close to you requires tailored and thorough treatment, this facility creates a nurturing and effective setting for the recovery journey.

Charlotte Behavioral Healthcare Inc

Charlotte Behavioral Healthcare Inc., situated in Punta Gorda, FL, delivers extensive rehabilitation support for individuals of all ages. The facility is dedicated to specialized care for addiction, withdrawal management, and dual diagnoses. Offering services that include round-the-clock hospital inpatient care, hospital inpatient detoxification, and outpatient options, each person benefits from customized support for their path to recovery. Distinctive programs are available for teenagers, adult men, and adult women. Through methods like 12-step facilitation, anger management techniques, and brief intervention strategies, the center emphasizes excellent, gender-tailored treatment to foster healing and well-being.

Chemical Abuse Services Agency Inc

Chemical Abuse Services Agency Inc, situated in Bridgeport, CT, delivers an extensive array of treatment options for adult women facing substance use disorders alongside mental health challenges. The center offers both intensive outpatient and general outpatient programs, as well as targeted treatments using methadone, buprenorphine, or naltrexone. Emphasizing therapeutic methods such as anger management, brief interventions, and cognitive-behavioral therapy, the facility is designed to support individuals across various age groups, including seniors and young adults. Additionally, the center features specialized programs tailored for clients who have suffered from intimate partner violence, domestic violence, and sexual abuse, creating a nurturing and welcoming atmosphere for women on their recovery journey.

Chemical Abuse Services Agency Inc

Situated in Bridgeport, CT, the Chemical Abuse Services Agency Inc delivers an extensive array of services aimed at treating substance use issues. This center features hospital inpatient care, intensive outpatient programs, and transitional living arrangements, including halfway houses and sober living facilities. It offers specialized services for active-duty service members, adult men and women, and incorporates various methods such as 12-step programs and anger management. Catering to adults and young adults of all genders, the center emphasizes high-quality treatment using evidence-based strategies like brief interventions.

Chemical Addictions Recovery Effort

Chemical Addictions Recovery Effort, situated in Panama City, FL, provides extensive programs for individuals of all ages struggling with substance dependence and co-occurring mental health conditions. The center offers both intensive outpatient and standard outpatient care, which includes methadone and buprenorphine treatment. Their approach incorporates 12-step facilitation, anger management techniques, and brief intervention strategies. This facility is equipped to serve active duty military personnel, teenagers, and adult men. Welcoming all genders, they are committed to delivering customized treatment plans. For those in pursuit of a high-quality, individualized, and caring path to addiction recovery, this program stands out.

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Siler City, NC

Chatham Recovery PLLC, located in Siler City, NC, is committed to delivering thorough substance abuse rehabilitation. This establishment provides outpatient detoxification and medication-assisted treatment using methadone, buprenorphine, or naltrexone. Additionally, it incorporates therapeutic methods like 12-step program support, anger management techniques, and brief intervention strategies. The center features tailored programs for adult males, adult females, and individuals affected by intimate partner or domestic violence, addressing a wide spectrum of client requirements. Catering to adults, youth, and older adults across all genders, Chatham Recovery PLLC emphasizes personalized care for every individual. Discover caring and successful treatment here, where excellent service is paramount.

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Situated in Panama City, FL, the Chemical Addictions Recovery Effort specializes in extensive detox programs designed for both adults and young adults facing substance dependency issues. This center offers residential detox services alongside 24/7 support within a nurturing environment. Emphasizing methods such as 12-step support, brief interventions, and motivational interviewing, the facility customizes its strategies to suit each individual's requirements. It features specialized programs for active military members, as well as distinct offerings for adult men and women. Accredited by CARF, the center guarantees superior care for clients of all genders seeking constructive treatment for chemical dependencies.

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Chenango Co Behavioral Hlth Servs OP, situated in Norwich, NY, provides extensive outpatient services aimed at addressing substance use issues, co-occurring mental health conditions, and trauma recovery. This center focuses on the needs of adults and seniors, offering customized programs tailored for both men and women. By employing evidence-based techniques such as cognitive behavioral therapy and the Matrix Model, the facility ensures high-quality support for those on the path to recovery. Furthermore, Chenango Co Behavioral Hlth Servs OP offers specialized care for clients with trauma backgrounds, including outpatient treatments with methadone, buprenorphine, or naltrexone, committed to fostering enduring health and well-being.

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Situated in Gaffney, SC, the Cherokee County Commission provides extensive treatment options for individuals dealing with substance use issues, including adults and seniors. The facility offers various levels of care, such as intensive outpatient treatment, outpatient services, and day treatment/partial hospitalization programs. Emphasizing approaches like 12-step facilitation, anger management, and brief intervention, this center serves both men and women. Specialized programs are also available for adolescents as well as adult males and females. With a commitment to high-quality care and customized treatment plans, the center stands out as an excellent choice for those in need of effective addiction recovery services.

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New Tazewell, TN

Cherokee Health Systems, situated in New Tazewell, TN, delivers comprehensive outpatient care for adults battling substance use and for individuals of all ages experiencing co-occurring mental health challenges. Employing proven techniques like anger management, cognitive behavioral therapy, and brief intervention, the center is dedicated to personalized treatment plans, especially for those with dual diagnoses. Cherokee Health Systems offers a spectrum of outpatient services, including methadone, buprenorphine, or naltrexone treatment, alongside general outpatient support for adults and seniors across all genders. Discover effective, individualized support at Cherokee Health Systems.

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Cherokee Health Systems, located in Knoxville, TN, provides an extensive variety of outpatient programs aimed at supporting both adults and young adults dealing with substance use issues. This center excels in addressing both substance use disorders and severe mental health concerns, offering tailored therapies that include anger management, cognitive-behavioral therapy, and short-term interventions. It features specialized programs for those with simultaneous challenges of pain and substance abuse. Prioritizing high-quality and individualized treatment, Cherokee Health Systems serves a diverse clientele, accepting both men and women in need of outpatient care involving methadone, buprenorphine, or naltrexone treatment, alongside regular outpatient support.

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Maynardville, TN

Cherokee Health Systems, located in Maynardville, TN, specializes in outpatient services for adults dealing with substance use issues and co-occurring serious mental health disorders, alongside offering support for children's emotional challenges. The center emphasizes personalized treatment through methods such as cognitive behavioral therapy and motivational interviewing. Each program is customized to meet individual needs, ensuring that clients receive thorough and tailored care. Their offerings include outpatient treatment options with methadone, buprenorphine, or naltrexone, facilitating effective pathways to recovery. With a commitment to high-quality care, this facility serves adults and seniors of all backgrounds, aiding them in their quest for sustained sobriety and improved mental health.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)