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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Childrens Home of Northern Kentucky

The Childrens Home of Northern Kentucky, located in Covington, KY, provides comprehensive specialized care for individuals of all ages grappling with substance abuse and co-occurring mental health conditions. They offer a spectrum of therapeutic modalities, including intensive outpatient, standard outpatient, and day treatment services, all tailored to meet individual needs. Their therapeutic framework incorporates proven techniques such as cognitive behavioral therapy, anger management, and brief interventions. The center also features dedicated programs for adolescents, trauma survivors, and those facing dual diagnoses. Open to adults and seniors across all gender identities, The Childrens Home of Northern Kentucky is committed to delivering high-quality, evidence-based treatment to foster lasting recovery.

CHOICE Program
Indianapolis, IN

Situated in Indianapolis, IN, the CHOICE Program delivers extensive services for addiction treatment. This center offers hospital inpatient detoxification, round-the-clock care, and outpatient services tailored for both adults and older adults. With a focus on substance use recovery, the facility serves female clients, including active military members, adult women, and young individuals. Employing evidence-based methods such as brief interventions, motivational interviewing, and relapse prevention strategies, the program is designed to provide customized care for every participant. Emphasizing high standards and specialized programs for diverse groups, the CHOICE Program is recognized as a reliable option for individuals in need of effective rehabilitation.

CHRIS 180 Inc
Atlanta, GA

CHRIS 180 Inc, located in Atlanta, GA, presents a wide array of addiction recovery services designed to meet the unique requirements of each client. The center specializes in intensive outpatient care, outpatient detox support, and various programs aimed at adults and older adults. Emphasizing techniques such as cognitive behavioral therapy, anger management, and brief interventions, clients receive tailored support for substance use disorders and co-occurring mental health issues. Additionally, specialized programs are offered for teenagers and young adults. CHRIS 180 Inc accommodates both men and women, fostering a welcoming and supportive atmosphere for everyone. Discover effective care and research-supported treatments at this center committed to guiding individuals toward long-term recovery.

Christian Community Health Center

Located in Chicago, IL, the Christian Community Health Center specializes in outpatient programs for substance use treatment. The center employs a range of methodologies, including 12-step programs, brief interventions, and cognitive behavioral therapy, to assist clients. It features targeted services for individuals who have faced trauma, those living with HIV or AIDS, and patients dealing with both mental health and substance use challenges. The center's offerings are designed for adults and seniors of diverse backgrounds and include outpatient options with methadone, buprenorphine, or naltrexone treatment, along with standard outpatient services. Emphasizing personalized care and effective treatment strategies, this center fosters a nurturing atmosphere for individuals on their path to recovery from substance use issues.

Christiansburg Comprehensive Trt Ctr

Christiansburg Comprehensive Trt Ctr, situated in Christiansburg, VA, delivers a full spectrum of outpatient care for addiction and recovery. Their services include outpatient detox, medication-assisted treatment with methadone, buprenorphine, or naltrexone, and they utilize proven therapies like anger management, CBT, and the Matrix Model. This center is particularly dedicated to serving pregnant and postpartum women, as well as adults and young adults, regardless of gender. Christiansburg Comprehensive Trt Ctr is a prime option for individuals looking for personalized and effective treatment for substance use challenges due to their high standards and customized approach.

Christian Community Health Center

Situated in Calumet City, IL, the Christian Community Health Center offers a wide range of services for individuals battling substance use issues. This facility specializes in outpatient therapies including methadone/buprenorphine or naltrexone treatments, standard outpatient care, along with 12-step support, brief intervention strategies, and cognitive behavioral therapy. The center also features specialized programs for clients who have faced trauma, those living with HIV or AIDS, and individuals managing both mental health and substance use challenges. Catering to adults and seniors of all genders, this center provides compassionate care in a nurturing setting, focused on the distinct needs of each person on their road to recovery.

Christophers Reason
Staten Island, NY

Christophers Reason, situated in Staten Island, NY, provides a complete spectrum of addiction recovery support. Their offerings include detox services, treatment for substance misuse, temporary housing, and sober living arrangements. The center's programs encompass intensive outpatient care, extended residential stays, and standard outpatient services. Specializing in techniques such as anger management, brief intervention, and cognitive behavioral therapy, Christophers Reason supports young people and adults of all genders. They are dedicated to delivering excellent care that is customized to each person's unique situation. For those in search of successful rehabilitation with a customized strategy, Christophers Reason stands as a significant resource for achieving lasting recovery.

Child and Family Guidance Centers

Child and Family Guidance Centers, located in Kingston, NY, provides an extensive range of substance abuse treatment services for adults facing concurrent mental health issues, as well as for children dealing with significant emotional challenges. Their intensive outpatient services are based on validated techniques, incorporating methods like 12-step facilitation, anger management, and short intervention strategies. The center caters to specific needs with programs designed for adolescents, adult men, and adult women, offering personalized support for diverse age and gender groups. Whether individuals are looking for outpatient services or methadone/buprenorphine therapy, the center is committed to delivering high-quality care and guidance on their recovery journey.

Child Center of NY

The Child Center of NY, situated in Jamaica, NY, provides extensive support for individuals of all ages dealing with substance use issues and significant emotional challenges. Their services include outpatient care options such as methadone and buprenorphine treatment, alongside general outpatient services. Therapeutic interventions employed include anger management techniques, cognitive behavioral therapy, and motivational interviewing. A specific program is available for adult men, and services are extended to adult men and women, as well as seniors. The Child Center of NY is dedicated to fostering a nurturing and effective setting for those aiming to manage substance dependencies and associated mental health concerns.

Chris Kyle Patriots Hospital

Chris Kyle Patriots Hospital, located in Anchorage, AK, provides a wide array of treatment options for adults and young adults facing substance use issues and concurrent mental health challenges. This center specializes in inpatient detoxification and treatment, catering to the unique needs of active duty military members and those who have undergone traumatic experiences. Emphasizing 12-step support, anger management strategies, and short-term intervention techniques, the facility tailors its care to accommodate both male and female patients. Its dedication to high-quality treatment and fostering long-term recovery establishes it as an excellent option for individuals in need of effective rehabilitation.

Chillicothe Treatment Services

Chillicothe Treatment Services, located in Chillicothe, OH, provides dedicated addiction recovery services utilizing several outpatient methodologies, including medication-assisted treatment with methadone, buprenorphine, or naltrexone. The facility employs scientifically validated therapeutic techniques like anger management, brief intervention strategies, and cognitive behavioral therapy. Their specialized programming addresses the unique requirements of adult males, adult females, and individuals who are pregnant or postpartum. Serving a broad demographic of adults and young adults regardless of gender, this establishment ensures thorough care. By prioritizing effective treatment and personalized assistance, Chillicothe Treatment Services is a distinguished option for those pursuing impactful recovery in the region.

Chilton County Treatment Center

Chilton County Treatment Center in Clanton, AL, delivers extensive support for those overcoming addiction and co-occurring mental health challenges. Their offerings include detox services, intensive outpatient care, and outpatient detox, designed for adults and young adults. The center also features distinct programs for active military, men, and women, promoting personalized treatment. Employing methods like 12-step support, anger management, and brief intervention, the facility is dedicated to high-quality care and assistance for everyone pursuing recovery.

Childrens Campus
Raleigh, NC

Nestled in Raleigh, NC, Childrens Campus provides extensive recovery support for individuals battling addiction and co-occurring psychological challenges. They serve both younger and adult populations, offering various care models including round-the-clock residential stays, structured outpatient sessions, and round-the-clock residential care. Employing proven therapeutic methods like cognitive behavioral therapy, anger management techniques, and brief intervention strategies, the center welcomes clients of all ages and genders. Their specialized services are designed for teens, those with dual diagnoses, and individuals managing chronic pain alongside substance dependence, ensuring personalized treatment plans. Clients can anticipate superior care and assistance at Childrens Campus.

Chrysalis House Inc
Lexington, KY

Chrysalis House Inc in Lexington, KY, stands as a distinguished rehabilitation facility dedicated to assisting adult women overcome substance use challenges. They provide extended residential care for individuals grappling with both addiction and significant mental health conditions. Employing strategies like 12-step facilitation, anger management techniques, and brief intervention methods, Chrysalis House Inc delivers thorough treatment plans customized for each person. Their specialized services are designed for adult women, including those who have experienced intimate partner violence, domestic abuse, and sexual trauma. Catering to adults, seniors, and young adults, this center fosters a secure and encouraging atmosphere for women on their journey to recovery and well-being.

Chrysalis House Inc
Lexington, KY

Chrysalis House Inc, located in Lexington, KY, is dedicated to providing focused substance use treatment for adult women who are also managing serious mental health conditions or emotional challenges. Their offerings include extended stay, brief stay, and round-the-clock residential care, all personalized to meet individual needs. Treatment modalities encompass 12-step integration, techniques for managing anger, and concise therapeutic interventions. Special programs are available for those who have experienced intimate partner violence, domestic abuse, or sexual assault. Catering to adults, young adults, and older adults, this center prioritizes a women-centered approach within a secure and nurturing setting. Chrysalis House Inc is committed to delivering effective care with empathy, guiding individuals toward lasting recovery.

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Concord, NH

Situated in Concord, NH, "Choices" features a wide array of substance use recovery programs designed for adults and seniors. This center offers various options including intensive outpatient treatment, outpatient care, and outpatient programs for methadone, buprenorphine, or naltrexone. By implementing evidence-based methods such as brief interventions, cognitive behavioral therapy, and motivational incentives, "Choices" customizes its offerings to fit each person's unique circumstances. The facility provides specialized programs for adolescents and distinct services for adult men and women, fostering a welcoming atmosphere for all individuals. Committed to delivering top-notch care, "Choices" is recognized for its dedication to assisting people in overcoming addiction and achieving enduring recovery.

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Situated in South Holland, IL, the Christian Community Health Center specializes in extensive treatment for substance use through its outpatient services. The center offers a range of formats, such as outpatient treatments utilizing methadone, buprenorphine, or naltrexone, along with regular outpatient care and 12-step support. Emphasizing brief interventions and cognitive behavioral therapy, this facility serves adults and seniors of various gender identities. It also features specialized programs for individuals who have faced trauma, those living with HIV or AIDS, and clients dealing with both mental health and substance use challenges. The center's dedication to high-quality care positions it as an essential resource for personalized and effective addiction recovery.

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Christian Family Counseling in Mankato, MN, provides comprehensive rehabilitation for adults and young adults facing substance abuse and dual-diagnosis issues. Their treatment options include intensive outpatient, day treatment, and partial hospitalization programs. Emphasizing anger management, CBT, and motivational interviewing, they create individualized plans for each client. Specialized tracks for men, women, and trauma survivors ensure tailored support. This center is committed to offering excellent, person-centered rehabilitation in a nurturing setting for all genders.

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Florence, SC

The Chrysalis Center in Florence, SC, is dedicated to providing expert substance use therapy within a secure and encouraging setting. This institution features both long-term residential and around-the-clock residential options, specifically designed for adult women who have endured intimate partner violence, domestic abuse, or sexual assault. By emphasizing strategies such as anger management, short-term intervention, and cognitive behavioral techniques, the center serves adults, older adults, and young adults in need of thorough support. Its distinct method for meeting the requirements of its female clientele distinguishes it, promising excellent and personalized treatment for individuals pursuing recovery.

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Crownsville, MD

Chrysalis House Inc, situated in Crownsville, MD, delivers extensive treatment for substance use disorders and provides supportive housing for adult women. This center focuses on individuals managing co-occurring mental health and substance use issues, as well as those impacted by domestic violence or sexual trauma. Offering a spectrum of care from outpatient services to extended residential stays, Chrysalis House Inc employs proven methods such as 12-step integration, anger management techniques, and short-term counseling. Designed for adults and older adults, the center is dedicated to exceptional care and guidance throughout the recovery process.

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Anchorage, AK

Chugachmiut, located in Anchorage, AK, stands out as a prominent rehabilitation facility that specializes in outpatient services for both substance use disorders and co-occurring mental health challenges affecting children and adults. Their programs are grounded in evidence-based practices, featuring options such as 12-step facilitation, anger management, and brief therapeutic interventions. The center serves a diverse clientele, including adolescents and adult men and women, ensuring tailored support for each demographic. With an emphasis on providing personalized care for adults and seniors of all genders, Chugachmiut is dedicated to delivering exceptional treatment that promotes recovery. If you or someone dear to you is looking for thorough addiction support in a nurturing and encouraging setting, consider Chugachmiut for their effective and empathetic approach to care.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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