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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Changing Tides
Kitty Hawk, NC

Nestled in Kitty Hawk, NC, "Changing Tides" delivers complete addiction recovery care for adults and young adults. The center provides detox, substance abuse therapy, and supportive transitional housing. Tailored programs like intensive outpatient, day treatment, and partial hospitalization are available, incorporating methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. Catering to both men and women, "Changing Tides" emphasizes a personalized, whole-person path to healing, offering excellent support for individuals battling addiction.

Chapa de Indian Health Program Inc

Chapa de Indian Health Program Inc, located in Auburn, CA, provides extensive outpatient care for those needing detoxification, help with substance use, and support for co-occurring mental health challenges. They have distinct programs designed for pregnant and postpartum women, addressing the specific requirements of adults and older adults, with gender-sensitive treatment available for men and women. The center employs methods like anger management, brief intervention, and cognitive behavioral therapy to customize treatment plans. Additionally, their outpatient detoxification services and methadone/buprenorphine treatment options improve the ease of access and success of their care, ensuring excellent treatment for everyone requiring it.

Chapters Recovery Center Inc

Chapters Recovery Center Inc. in Danvers, MA, is dedicated to providing comprehensive addiction treatment alongside specialized care for concurrent mental health challenges affecting adults and younger individuals. They offer a range of treatment modalities including intensive outpatient, outpatient, and day treatment, complemented by personalized therapeutic approaches like 12-step facilitation, anger management techniques, and brief intervention strategies. The center distinguishes itself with distinct programs catering to active-duty military personnel, as well as specific support for adult men and women, ensuring a highly personalized recovery journey. Open to all genders within the adult and young adult population, Chapters Recovery Center Inc. emphasizes high-quality care and a holistic approach aimed at fostering enduring sobriety and well-being.

Charles K Post Addiction Treatment Ctr

Situated in Brentwood, NY, the Charles K Post Addiction Treatment Ctr delivers focused programs for overcoming substance dependency within a nurturing setting. This institution features inpatient services emphasizing 12-step integration, emotional regulation techniques, and brief counseling strategies. The treatment is designed for adult men and women, including individuals affected by domestic abuse. The center also offers interim housing and sober living accommodations, serving adults and adolescents in need of brief inpatient stays. Their dedication to excellent support and personalized recovery plans establishes them as a significant provider for individuals pursuing help with addiction.

Charles River Recovery LLC

Charles River Recovery LLC, situated in Weston, MA, delivers thorough programs for substance abuse, encompassing detoxification. This center provides hospital-level inpatient detox and care, with tailored services for adult men, women, and active military. Employing methods like 12-step facilitation and anger management, the facility serves adult men and women, as well as young adults. Prioritizing exceptional care and personalized plans, Charles River Recovery LLC is committed to supporting individuals in their path to regaining health.

Charleston Area Medical Center

Charleston Area Medical Center located in Charleston, WV, provides a wide range of services for individuals battling addiction, encompassing both adults and young adults. This facility specializes in inpatient detoxification and addresses various substance use disorders alongside any concurrent mental health issues. With targeted programs designed for men, women, and those with dual diagnoses, treatment is customized to meet the unique requirements of each client. The center employs methods such as brief intervention, cognitive behavioral therapy, and strategies for preventing relapse, ensuring exceptional care for all patients. For those in search of tailored addiction treatment in a hospital environment, this center is committed to supporting your recovery journey.

Charleston Comprehensive Trt Ctr

Charleston Comprehensive Trt Ctr, located in Charleston, WV, provides comprehensive outpatient care for individuals and young adults grappling with addiction. Their expertise includes withdrawal management and addiction therapy, offering services such as outpatient detox, medication-assisted treatment (methadone, buprenorphine, naltrexone), and remote counseling. The center emphasizes strategies for maintaining sobriety and offers counseling for addiction, customizing its offerings for active military, adult males, and females. Serving both men and women, this institution is dedicated to high standards of care and personalized rehabilitation plans.

Channel Islands Rehab

Channel Islands Rehab, situated in Oxnard, California, delivers extensive addiction recovery services tailored for both adults and young adults. The center features a hospital-based inpatient detox and treatment program that includes specialized options for active military members, as well as for adult males and females. Treatment methodologies employed here encompass 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. Channel Islands Rehab also supports individuals dealing with both substance use disorders and significant mental health challenges. With a commitment to high-quality care, this facility prioritizes the specific requirements of clients on their journey to overcoming addiction.

Charak Center for Health and Wellness

Charak Center for Health and Wellness in Cleveland, OH, delivers comprehensive rehabilitation solutions. Their expertise lies in addressing addiction and dual diagnoses for both adults and minors, offering robust intensive outpatient and standard outpatient options, notably including methadone/buprenorphine services. Prioritizing personalized support, they utilize therapeutic techniques like anger management, cognitive behavioral therapy, and the Matrix Model. Open to individuals of any gender, Charak Center distinguishes itself with customized recovery strategies designed for sustained wellness.

Changes Carrollton Springs

Carrollton Springs, located in Plano, TX, provides a wide array of evidence-supported rehabilitation programs for individuals dealing with substance abuse and co-existing mental health issues, targeting both adults and children. The services offered include intensive outpatient programs, outpatient day services, and partial hospitalization. The center focuses on techniques such as brief intervention, cognitive behavioral therapy, and strategies for preventing relapse. Specialized programs are available for active military members, LGBTQ individuals, and those facing dual diagnoses. Catering to a diverse population of adults and young adults, this facility is committed to delivering exceptional care within a nurturing atmosphere. If you're in search of effective and empathetic support for addiction recovery, Carrollton Springs stands out as an exemplary option.

Charles Evans Center at Glen Cove

The Charles Evans Center, situated in Glen Cove, NY, provides extensive outpatient services for individuals of all ages struggling with substance use issues. This facility is particularly adept at treating those with co-occurring mental health conditions. Their expertise includes anger management, brief intervention strategies, and cognitive behavioral therapy, allowing for personalized treatment plans, especially for those with a history of trauma. The center features dedicated programs for adult women and a strong emphasis on supporting individuals facing concurrent mental health and substance use challenges, ensuring each client receives customized care. The Charles Evans Center is committed to delivering excellent support and treatment, including outpatient options for methadone, buprenorphine, or naltrexone, to all individuals pursuing recovery.

Charak Center for Health and Wellness

Charak Center for Health and Wellness, located in Stow, OH, provides targeted substance misuse treatment services for both adults and young adults facing serious mental health challenges or emotional issues in children. Their outpatient and intensive outpatient programs are designed with personalized strategies and offer gender-specific treatment options for both men and women. The center employs proven methods, including anger management, cognitive behavioral therapy, and the Matrix Model, ensuring thorough assistance for individuals on their path to recovery. With an emphasis on high-quality care and customized treatment approaches, Charak Center for Health and Wellness is dedicated to meeting the distinct needs of each client.

Charak Center for Health and Wellness

The Charak Center for Health and Wellness, located in Elyria, OH, specializes in addressing substance use issues along with co-occurring mental health disorders. The center offers a wide range of programs, including intensive outpatient services, regular outpatient support, and options for methadone, buprenorphine, or naltrexone treatments. By utilizing evidence-based practices such as cognitive behavioral therapy, anger management techniques, and the Matrix Model, they ensure personalized care for both adults and young adults. Charak Center emphasizes a tailored approach, welcoming both male and female clients in need of effective rehabilitation within a nurturing atmosphere.

Charak Center for Health and Wellness

Charak Center for Health and Wellness, located in Medina, OH, provides tailored treatment for substance use and co-occurring disorders for both adults and children. Their outpatient services feature methods such as methadone and buprenorphine therapy, grounded in evidence-based practices including cognitive behavioral therapy and the Matrix Model. Prioritizing individualized care, the center supports adults and young adults alike, offering gender-responsive services for males and females. Notably, Charak Center emphasizes anger management and customized therapy, distinguishing itself through its commitment to delivering high-quality, personalized rehabilitation for individuals facing addiction and mental health issues.

Charak Center for Health and Wellness

The Charak Center for Health and Wellness, situated in Mentor, OH, is dedicated to offering expert treatment for substance use disorders in adults and young adults who are also managing significant mental health challenges or emotional distress. Their program includes intensive outpatient and standard outpatient services, employing proven therapeutic techniques such as anger management, cognitive behavioral therapy, and the Matrix Model. Emphasizing personalized care, the center serves both male and female individuals in need of effective rehabilitation. This facility distinguishes itself through its customized treatment plans and unwavering dedication to meeting the specific requirements of every client.

Charleston Center of Charleston County

Nestled in North Charleston, SC, the Charleston Center of Charleston County delivers extensive care for substance abuse. Their offerings include detox and a variety of treatment options such as intensive outpatient, long-term residential, and standard outpatient care. Employing methods like anger management, brief intervention, and cognitive behavioral therapy, they support adolescents, adult men, and adult women. This facility also extends its services to seniors of all genders, prioritizing tailored treatment plans and proven therapeutic techniques to guide individuals toward lasting recovery. The Charleston Center stands as a dedicated provider of specialized addiction services.

Changes Springs Dublin

Changes Springs Dublin, located in Dublin, OH, provides a holistic approach to treating substance use disorders in both adults and children, particularly those facing simultaneous mental health challenges. The center features a range of treatment options, including intensive outpatient programs, outpatient day treatments, and partial hospitalization. It specializes in tailored programs for youths, women, and those with co-occurring conditions, addressing a wide spectrum of needs. By employing methodologies such as 12-step support, anger management, and brief intervention strategies, the facility focuses on personalized care. Accommodating clients of all genders, it emphasizes high-quality treatment to foster sustainable recovery for individuals grappling with addiction and mental health issues.

Changing Echoes
Angels Camp, CA

Located in Angels Camp, CA, Changing Echoes is a dedicated facility providing extensive support for individuals overcoming addiction. They focus on long-term residential stays, safe detoxification within a residential setting, and round-the-clock residential care for both adults and younger adults. Their therapeutic methods include 12-step integration, anger management techniques, and brief intervention strategies to create individualized recovery plans. Changing Echoes is particularly committed to serving adult men and women, including those who have faced intimate partner or domestic violence, fostering a safe and welcoming atmosphere. Their dedication to customized care and scientifically proven methods positions them as an excellent option for those pursuing successful recovery.

Changing Lives at Home Mental Health

"Changing Lives at Home Mental Health in Baltimore, MD, delivers thorough treatment for substance abuse and concurrent mental health issues for both adults and children. It features specialized programs tailored for active military personnel, teenagers, and adult males. The center offers both intensive outpatient and outpatient care, including options for daytime treatment. By employing proven methods such as 12-step support, anger management, and short interventions, the facility accommodates male and female clients of various ages. Its dedication to high standards of care and personalized treatment strategies makes it a trusted option for individuals pursuing successful rehabilitation."

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Changing Turn Community Healthcare, located in Edgewood, MD, provides extensive care for adults and young adults battling addiction, especially those also dealing with significant mental health or emotional challenges. Their services include intensive outpatient care, standard outpatient services, and day treatment or partial hospitalization programs. The center employs therapeutic techniques such as anger management, brief intervention, and cognitive behavioral therapy, customizing each treatment plan to the client's unique needs. Catering to both men and women, the facility emphasizes gender-specific support throughout the recovery process. Changing Turn Community Healthcare is distinguished by its commitment to delivering excellent, individualized care, aiding individuals on their journey toward lasting recovery.

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Charleston Residential Services, located in Las Vegas, NV, provides an extensive array of addiction recovery services encompassing detox, treatment for substance use disorders, transitional housing, and sober living options. The facility emphasizes hospital-based inpatient detoxification and treatment, utilizing strategies like 12-step facilitation, brief interventions, and cognitive behavioral therapy. Special programs are designed for active military members, adult women, and those who have faced trauma. Catering to both adults and young adults, regardless of gender, Charleston Residential Services is committed to delivering high-quality support and care for those aiming to overcome substance abuse challenges.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)