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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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CNV Detox Inc
Los Angeles, CA

Located in Los Angeles, CA, CNV Detox Inc delivers a wide range of services aimed at treating addiction. This center specializes in hospital-based inpatient detox and therapeutic programs designed for both adults and young adults who are grappling with substance abuse and related mental health challenges. CNV Detox Inc utilizes methods such as 12-step support, brief interventions, and cognitive behavioral therapy to create customized treatment plans. The facility offers special programs tailored for adult men, adult women, and individuals with dual diagnoses. Its dedication to high-quality care and individualized treatment options positions CNV Detox Inc as a leading option for effective rehabilitation.

Coachella Valley Recovery Ctr

Coachella Valley Recovery Ctr, located in Cathedral City, CA, delivers a wide range of addiction treatment options for both adults and young adults. The center specializes in hospital-based detox services and addresses substance use issues along with accompanying serious mental health challenges. Catering to a variety of demographics, including active duty military and adult men and women, the facility personalizes its services to address unique requirements. Employing techniques like 12-step programs, anger management, and concise interventions, the center guarantees tailored and impactful treatment. Committed to high-quality care, Coachella Valley Recovery Ctr also offers gender-specific initiatives to assist individuals in their recovery journey.

Coalition Recovery

Coalition Recovery, located in Tampa, FL, provides an extensive array of treatment solutions for those looking to address substance use challenges. Their services encompass intensive outpatient programs, day treatment options, and transitional living arrangements, aiming for a well-rounded recovery experience. The center employs proven methods such as cognitive behavioral therapy and 12-step strategies, focusing on both adults and young adults who may also be dealing with mental health issues. With tailored programs designed for active military personnel, men, and women, Coalition Recovery prioritizes customized care to meet various requirements. The facility fosters a nurturing atmosphere conducive to healing and personal development, making it a leading option for individuals in need of specialized rehabilitation assistance.

Coastal Community Behav Health LLC

Coastal Community Behav Health LLC, situated in Saint Marys, GA, delivers targeted care for individuals struggling with addiction. The center offers outpatient services designed for adults and young adults, encompassing medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient programs. Employing proven therapeutic methods like cognitive behavioral therapy, motivational incentives, and motivational interviewing, Coastal Community Behav Health LLC is committed to effective recovery. They also provide specialized support for those managing co-occurring pain and substance use issues, as well as for pregnant and postpartum women, tailoring treatment to individual circumstances. Both men and women receive comprehensive and effective care at this facility.

Coastal Detox Inc

Coastal Detox Inc, situated in Stuart, Florida, provides a full spectrum of recovery care, addressing detox, substance abuse, and co-occurring mental health conditions for both adults and minors. Operating as a hospital inpatient facility with round-the-clock services, they offer targeted programs for active military personnel, adult men, and adult women. Treatment methodologies employed include 12-step facilitation, anger management, and brief intervention. Coastal Detox Inc serves individuals of all genders, including adults and young adults, offering customized treatment plans. This center is committed to delivering high-quality, individualized care to guide those seeking to regain their health.

Coastwise Recovery Center

Situated in San Pedro, CA, Coastwise Recovery Center provides focused treatment for adults and young adults dealing with substance use issues, particularly those with concurrent severe mental health conditions. Their offerings encompass intensive outpatient and outpatient programs, featuring strategies such as 12-step facilitation, anger management, and brief intervention tactics. Emphasizing a personalized approach, the center serves both men and women. Clients can choose between outpatient day treatment and partial hospitalization, receiving exceptional care that meets their individual requirements. Coastwise Recovery Center is distinguished by its all-encompassing programs that tackle both substance use and mental health challenges, making it an excellent option for individuals ready to begin their recovery journey.

Coatesville Comprehensive Trt Center

Coatesville Comprehensive Trt Center, located in Coatesville, PA, provides expert care for substance use disorders through various programs customized to meet individual requirements. The center offers a variety of treatment options, including intensive outpatient care, outpatient services, and medication-assisted treatments with methadone, buprenorphine, or naltrexone. Employing strategies such as 12-step facilitation, coping skills development, and cognitive behavioral therapy, the facility serves adult men and women, including active military members. Focusing on both adults and young adults, the center ensures that all clients receive comprehensive support and high-quality care throughout their recovery process.

CODA Inc
Hillsboro, OR

CODA Inc, situated in Hillsboro, Oregon, delivers thorough substance use recovery programs for adults and young adults. Their services include intensive outpatient care, general outpatient support, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. CODA Inc focuses on methods like 12-step facilitation, anger management, and brief intervention strategies. The center offers customized programs designed for adult men, adult women, and individuals affected by intimate partner or domestic violence, ensuring personalized attention. CODA Inc is dedicated to providing high-quality rehabilitation and support for individuals overcoming substance use challenges.

Coastal Horizons Center Inc

Situated in Wilmington, NC, Coastal Horizons Center Inc provides extensive treatment for substance use issues affecting both adults and young adults. This center is adept at addressing co-occurring disorders alongside significant mental health challenges in adults, as well as emotional disturbances in children. Emphasizing intensive outpatient and standard outpatient services, Coastal Horizons Center Inc has tailored programs for adult males, adult females, and those who have faced intimate partner violence or domestic abuse. Their methods of treatment encompass anger management strategies, brief intervention techniques, and cognitive behavioral therapy. Committed to delivering high-quality care, this facility serves clients of all genders in their path to recovery and healing.

CODA Inc
Portland, OR

CODA Inc, located in Portland, Oregon, specializes in outpatient services for substance use disorders, offering treatments involving methadone, buprenorphine, or naltrexone alongside standard outpatient support. The center emphasizes therapeutic approaches such as cognitive behavioral therapy, anger management, and brief interventions, ensuring that it meets the needs of adult men and women, including those who have faced traumatic experiences. Catering to a diverse clientele of all genders, CODA Inc provides personalized care designed to support unique recovery journeys. With a dedication to delivering high-quality treatment and an array of tailored programs, this center stands as a source of hope for individuals pursuing effective and empathetic addiction recovery solutions.

Coastal Carolina Neuropsychiatric Ctr

Coastal Carolina Neuropsychiatric Ctr in Jacksonville, NC, provides targeted addiction recovery services for adults and adolescents. Their offerings include outpatient medication management with methadone, buprenorphine, or naltrexone, along with standard outpatient care. They also utilize cognitive behavioral therapy, individualized counseling for substance use disorders, and convenient virtual therapy sessions. This center is dedicated to personalized recovery journeys for all genders, emphasizing a complete strategy for overcoming addiction and delivering excellent care.

CODAC Behavioral Healthcare

In Cranston, RI, CODAC Behavioral Healthcare provides extensive addiction recovery support. Their expertise covers detoxification, managing substance dependency, and concurrent treatment for adults with serious mental health issues or children experiencing emotional distress. They offer various treatment levels, such as intensive outpatient services, standard outpatient care, and outpatient detoxification, employing proven methods like cognitive behavioral therapy and motivational incentives to foster sustained healing. Personalized programs are designed for adult men, adult women, and young adults, accommodating different age demographics and genders. CODAC Behavioral Healthcare distinguishes itself with its all-encompassing and personalized approach to recovery, serving adults and seniors.

Coastal Horizons Inc

Coastal Horizons Inc, situated in Shallotte, NC, offers a diverse array of services aimed at treating addiction in both adults and young adults. The center specializes in detoxification, substance use rehabilitation, and provides targeted support for those facing co-occurring mental health issues alongside substance use challenges. Their treatment modalities include intensive outpatient services, outpatient programs, and day treatment alternatives. Emphasizing evidence-based methodologies such as cognitive behavioral therapy and motivational incentives, Coastal Horizons Inc customizes its treatment plans to address the individual needs of each client. Additionally, the center features special programming designed for clients involved with the criminal justice system. Both male and female clients benefit from high-caliber, gender-specific treatment within this distinguished rehabilitation center.

Cobb County Community Services Board

The Cobb County Community Services Board in Marietta, GA, delivers extensive addiction recovery programs for adults and young adults. Their expertise includes initial detoxification, ongoing substance use therapy, and support for dual diagnoses. The center provides both in-person and live-in detox options, customized for each person's unique situation. Employing proven therapeutic methods such as cognitive behavioral therapy and the Matrix Model, they ensure high-quality care for individuals facing both addiction and mental health challenges. Emphasizing short-term interventions and distinct tracks for men and women, this establishment is committed to offering impactful and supportive recovery services.

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Situated in Indio, California, Coachella Valley Treatment Center specializes in outpatient detox and substance use rehabilitation services for both adults and seniors. Emphasizing anger management, cognitive behavioral therapy, and motivational interviewing, this center delivers focused support for clients who have faced issues related to intimate partner or domestic violence. Programs are customized for adult males and females, promoting personalized care. The facility also provides outpatient treatment options with methadone, buprenorphine, or naltrexone. Dedicated to high-quality care, Coachella Valley Treatment Center creates a nurturing space for those aiming to conquer substance use challenges.

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Situated in Brunswick, GA, Coastal Community Behavioral Health specializes in outpatient programs for substance use treatment. This center offers a variety of services such as relapse prevention, counseling for substance use disorders, and telehealth therapy options. Their tailored programs support adult men, women, pregnant and postpartum women, as well as young adults. Emphasizing personalized care, the facility accommodates clients of all genders. Coastal Community Behavioral Health is distinguished by its holistic approach to addiction recovery, delivering high-quality support for adults pursuing recovery in the Brunswick region.

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Situated in Rocky Point, NC, Coastal Horizons Center Inc delivers tailored treatment for substance use issues and associated mental health disorders for both adults and children. Their outpatient services encompass intensive outpatient programs along with methadone and buprenorphine assistance. Emphasizing strategies such as 12-step facilitation, cognitive behavioral therapy, and brief intervention techniques, the center offers customized care for both elderly and adult clients of various genders. Specialized initiatives are available for adult males, females, and those who have experienced intimate partner violence. Coastal Horizons Center Inc is committed to ensuring high-quality, personalized treatment aimed at fostering enduring recovery and improved mental health.

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Coastal Horizons Center Inc, situated in Burgaw, NC, provides extensive care for individuals of all ages struggling with substance use disorders and co-occurring mental health conditions. Their service offerings include intensive outpatient, outpatient, and medication-assisted treatment with methadone or buprenorphine. Emphasizing methodologies such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center crafts personalized programs for various demographics, including adults, older adults, women, and men. They have a particular expertise in serving adolescents, ensuring each individual receives a tailored treatment approach. Coastal Horizons Center Inc is dedicated to offering superior, gender-informed addiction treatment within a nurturing and empathetic setting.

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Seaside, OR

Situated in Seaside, OR, CODA Inc provides outpatient treatment services for substance use aimed at both adult men and women, along with young adults. This center specializes in managing anger, conducting brief interventions, and employing cognitive behavioral therapy, offering personalized support for those who have faced trauma. CODA Inc features dedicated programs for adult men, adult women, and survivors of trauma, ensuring that each individual receives customized care. By providing outpatient options such as methadone/buprenorphine or naltrexone therapies, the center emphasizes high-quality care and proven methods to assist clients in achieving enduring recovery.

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East Providence, RI

Situated in East Providence, RI, CODAC Behavioral Healthcare delivers a wide array of evidence-supported treatment options for adults and young adults facing challenges related to substance use and concurrent mental health issues. The facility specializes in intensive outpatient care, outpatient services, and outpatient detox programs, employing methods like brief intervention, cognitive behavioral therapy, and motivational incentives. With tailored programs for adult men, adult women, and young adults, CODAC Behavioral Healthcare accommodates a variety of populations. Their dedication to providing high-quality care for individuals of all genders, including seniors, positions this center as a crucial asset for those in search of effective and customized addiction treatment solutions.

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CODAC Behavioral Healthcare in Pawtucket, RI, delivers a full spectrum of addiction recovery support. Their offerings encompass detox and comprehensive substance use therapy. Patients can access structured day programs, general outpatient care, and detoxification outside of a residential setting, all adapted to personal circumstances. CODAC employs proven methods like brief intervention, cognitive behavioral therapy, and motivational incentives. They serve adult men, adult women, and young adults, as well as older adults, providing specialized care for all genders to guide them toward lasting sobriety.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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