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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Community and Family Resources

Situated in Tipton, IA, Community and Family Resources provides a full range of substance abuse treatment services for adults, children, and teenagers. Their outpatient programs feature options such as methadone/buprenorphine or naltrexone treatment, employing evidence-based methods like cognitive behavioral therapy and motivational interviewing. With a commitment to personalized care, this center fosters a welcoming environment for all clients, regardless of gender. The facility's distinct focus on brief interventions guarantees that treatment is both targeted and efficient. For those in need of high-quality outpatient addiction support tailored to individual needs, this center is committed to guiding clients towards recovery.

Community Bridges Inc

Community Bridges Inc, located in Payson, AZ, specializes in a wide range of substance abuse treatment for adults, including individuals with concurrent mental health issues. This center offers various treatment modalities, including intensive outpatient, outpatient, and day programs that incorporate proven techniques like cognitive behavioral therapy and motivational interviewing. Featuring tailored programs designed for active military personnel, as well as specific services for adult men and women, this facility addresses a broad spectrum of needs. Community Bridges Inc is committed to providing personalized care to adults and young adults of all genders, fostering enduring recovery and health.

Community Bridges Inc

Community Bridges Inc in Payson, AZ provides extensive support for adults and young adults battling addiction. This center is particularly adept at addressing dual diagnoses, combining addiction treatment with care for significant mental health challenges. Their outpatient services incorporate evidence-based techniques like CBT, motivational interviewing, and relapse prevention, ensuring personalized recovery plans. Dedicated programs are available for active military members, as well as men and women in general. Community Bridges Inc also offers outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, serving all individuals committed to achieving sobriety.

Community Behavioral Health

Situated in Hamilton, OH, Community Behavioral Health delivers a complete suite of treatment options for individuals of all ages grappling with addiction and mental health concerns. Their services encompass intensive outpatient care, day treatment, and partial hospitalization, utilizing proven methods like anger management, cognitive behavioral therapy, and brief intervention. The center is equipped with specialized services for active military personnel, teenagers, and adult men, demonstrating a commitment to varied populations. Community Behavioral Health further customizes support through distinct programs for adults and older adults, and separate tracks for men and women, emphasizing personalized healing and recovery.

Community Assessment and Trt Servs Inc

Community Assessment and Trt Servs Inc located in Cleveland, OH, delivers an extensive selection of services for addiction recovery. The center offers various programs including intensive outpatient, long-term residential, and outpatient treatments, implementing methods like 12-step facilitation, anger management, and cognitive behavioral therapy. They provide specialized programs designed for adult men and women, as well as individuals who have faced domestic or partner violence. This facility excels in addressing co-occurring substance use disorders alongside significant mental health issues in adults, along with serious emotional challenges in children. Emphasizing personalized and quality care for adults and young individuals across all genders, this center is recognized for its comprehensive approach to rehabilitation.

Community Bridges Inc

Community Bridges Inc, located in Mesa, AZ, provides outpatient treatment for substance use and dedicated support for those facing both substance abuse issues and severe mental health disorders. Utilizing techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, the center designs customized treatment plans for adults and young adults. With programs specifically for active duty military personnel as well as for adult men and women, this center fosters a welcoming atmosphere for individuals of all genders. Their commitment to high-quality care and personalized treatment options establishes Community Bridges Inc as a reliable option for comprehensive rehabilitation services in the Mesa region.

Community and Family Resources

Community and Family Resources in Iowa City, IA, delivers dedicated detox programs for adults and young adults within a residential environment. This center prioritizes personalized attention, offering continuous assistance adjusted to every individual's requirements. Employing methods like brief intervention, motivational interviewing, and counseling for substance use disorders, the facility guarantees a thorough recovery journey. Featuring distinct services for both male and female individuals, Community and Family Resources serves a broad spectrum of people aiming for sobriety. Anyone looking for a nurturing and successful recovery program will discover excellent treatment and individualized support at this location.

Community Bridges Inc

Community Bridges Inc. in Tucson, AZ, provides comprehensive recovery solutions designed for adult men facing addiction and co-occurring psychological conditions. Their services include options for individuals who do not require 24-hour care as well as structured live-in programs. Treatment methodologies employed at the facility include encouragement of 12-step principles, cognitive behavioral approaches, and the evidence-based Matrix Model, ensuring that each person's recovery plan is personalized. Special attention is given to specific populations, such as active duty service members, survivors of domestic abuse, and older adults. Community Bridges Inc. stands out for its dedication to high standards and tailored support, offering a vital avenue for effective and individualized recovery from substance dependence.

Community Bridges Inc

Community Bridges Inc, located in Phoenix, AZ, delivers comprehensive care for individuals struggling with substance use and co-occurring mental health conditions. Their services cater to adults and young adults, encompassing a variety of therapeutic options such as intensive outpatient programs and medication-assisted treatment with methadone or buprenorphine. Employing proven methods like cognitive behavioral therapy and motivational interviewing, the center also offers specialized tracks for active duty military personnel, adult men, and adult women. Community Bridges Inc is dedicated to providing high-quality, personalized treatment plans to foster lasting recovery for all clients, regardless of gender.

Community and Family Resources

Situated in Iowa City, IA, Community and Family Resources presents an extensive array of treatment options to tackle substance use issues, dual mental health diagnoses, and emotional challenges for both adults and children. The facility offers outpatient services, transitional living, and sober housing solutions. Employing evidence-based methodologies like cognitive behavioral therapy and anger management, the center customizes treatment plans for each person. With a commitment to personalized care, it serves male and female clients across various age groups. Community and Family Resources is focused on delivering high-quality support to assist clients in attaining sustainable recovery.

Community and Family Resources

Situated in Iowa City, IA, Community and Family Resources delivers a wide array of services for those dealing with addiction. This center features intensive outpatient programs, general outpatient care, and specialized initiatives aimed at young people. With a focus on substance abuse and related mental health issues, the facility also provides transitional housing and sober living arrangements. Incorporating methods such as 12-step facilitation and anger management, the center serves individuals of all ages and genders. Community and Family Resources is committed to offering high-quality support and care to those pursuing recovery from addiction in a supportive environment.

Community Assessment and Trt Servs

Community Assessment and Trt Servs in Cleveland, OH, delivers thorough treatment for adults grappling with substance use and significant mental health challenges. The facility provides options such as intensive outpatient programs, regular outpatient services, and medication-assisted treatments including methadone, buprenorphine, or naltrexone. With a focus on personalized care, the center employs approaches like 12-step facilitation, anger management, and cognitive behavioral therapy. Specialized programs are available for adult males, adult females, and individuals affected by intimate partner violence. This center strives to offer exceptional care and support to adults and young adults of any gender seeking to overcome addiction and mental health issues.

Community Bridges Inc

Situated in Holbrook, AZ, Community Bridges Inc provides an extensive array of treatment options for substance use issues. This facility is known for addressing co-occurring disorders that involve substance use alongside significant mental health challenges in adults, as well as emotional difficulties in children. Available services include outpatient care, residential treatment, and short-term programs, utilizing proven techniques like cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. Community Bridges Inc specifically serves various demographics, including active military members, adult men and women, and young adults. The center emphasizes customized care for both male and female patients, ensuring personalized and effective treatment for anyone pursuing recovery.

Community Bridges Inc

Situated in Mesa, AZ, Community Bridges Inc provides outpatient treatment for substance use and is particularly adept at addressing co-occurring disorders in both adults and children. The center utilizes techniques such as cognitive behavioral therapy, motivational interviewing, and relapse prevention to offer personalized care that meets the unique needs of each individual. Catering to active duty military personnel, as well as adult men and women, Community Bridges Inc serves individuals of all genders, including young adults. For those in search of effective treatment within a nurturing atmosphere, this center offers extensive services that tackle both substance use and mental health issues. Its commitment to holistic care and evidence-based practices makes Community Bridges Inc a leading option for individuals on their recovery journey.

Community Bridges Inc

Community Bridges Inc, situated in Globe, AZ, delivers an extensive variety of services for individuals in need of substance use treatment and transitional housing. The center features outpatient, residential, and short-stay options that employ evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies. Community Bridges Inc also offers targeted programs for active duty military personnel, as well as adults of both genders, addressing a diverse array of needs. Their distinct focus on both substance use and mental health disorders allows for specialized support for adults and young adults alike. This facility fosters a nurturing atmosphere for those pursuing recovery, prioritizing personalized care that meets the specific requirements of each individual.

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Situated in Des Moines, IA, Community and Family Resources provides exceptional treatment for substance use disorders and specialized support for adults experiencing co-occurring substance use and significant mental health challenges, as well as for children dealing with severe emotional issues. This center offers both residential and short-term residential programs that incorporate customized approaches including 12-step methods, anger management strategies, and focused interventions. With a strong emphasis on tailored care, the facility serves adults and young adults across all gender identities. Community and Family Resources is distinguished by its dedication to quality care and individualized treatment plans, positioning it as a leading option for individuals in need of extensive rehabilitation services.

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In Washington, IA, Community and Family Resources provides extensive support for individuals battling substance use disorders via its outpatient services. The center offers targeted treatment options including outpatient care with methadone/buprenorphine or naltrexone, standard outpatient services, and brief intervention strategies. Employing proven methods such as cognitive behavioral therapy and contingency management/motivational incentives, the facility crafts personalized care plans for a diverse clientele, encompassing adults and young people of any gender. Community and Family Resources is distinguished by its dedication to customized recovery journeys and high-quality, individualized attention.

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Community and Family Resources, situated in Clive, IA, delivers outpatient care for adults struggling with substance use disorders. They also provide tailored interventions for individuals experiencing co-occurring substance use and mental health challenges, encompassing serious mental illness in adults and significant emotional disturbances in children. Their treatment modalities include 12-step facilitation, brief intervention strategies, and cognitive behavioral therapy. The center is equipped to serve a broad spectrum of individuals with specific programs for active duty military personnel, adolescents, and adult men. Catering to adults and seniors of all genders, Community and Family Resources ensures comprehensive support through outpatient medication-assisted treatment (methadone/buprenorphine or naltrexone) and general outpatient services.

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Community Behavioral Health, located in Indianapolis, IN, provides outpatient services that focus on substance use disorders and concurrent mental health issues affecting both adults and children. This center employs evidence-based methods, such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. Customized programs are designed specifically for adult women, individuals with a history of trauma, and people experiencing dual diagnoses. The facility caters to adults and young adults of all genders, fostering a nurturing atmosphere conducive to recovery. Committed to delivering high-quality care and personalized treatment, this center stands as a symbol of hope for individuals in need of thorough rehabilitation support.

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Community Behavioral Health in Salisbury, MD, delivers focused care for individuals of all ages grappling with addiction and co-occurring mental health challenges. Their therapeutic offerings include intensive outpatient, standard outpatient, and day treatment formats, incorporating evidence-based methods like anger management, brief interventions, and cognitive behavioral therapy. Specialized services are also available for those involved with the criminal justice system. Committed to gender-inclusive treatment for adults and seniors, the center prioritizes personalized, high-quality support. For those pursuing a path to recovery that integrates substance abuse treatment with mental wellness, Community Behavioral Health offers a comprehensive solution.

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Community Bridges Inc, located in Winslow, AZ, delivers extensive treatment for adults dealing with substance use issues, particularly those with concurrent mental health disorders. The center features both intensive outpatient and outpatient services, alongside specialized treatments using methadone/buprenorphine and naltrexone. Emphasizing cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, the facility customizes its care to meet the specific needs of its clients. It also offers tailored programs aimed at active duty military personnel as well as separate tracks for adult men and women to provide focused assistance. Committed to high-quality care, this center employs evidence-based practices to support sustained recovery for both adult and young adult clients of all genders.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)