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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Community and Family Resources

Situated in Fort Dodge, IA, Community and Family Resources provides a wide array of detox and substance abuse rehabilitation services. Emphasizing an all-encompassing strategy, this center delivers intensive outpatient, outpatient, and standard outpatient treatment options. It specializes in programs designed for teenagers, adult males, and adult females, serving clients of all genders and various age groups, from adolescents to adults. Community and Family Resources is distinguished by its customized treatment plans, committed to delivering high-quality support for individuals pursuing recovery from addiction.

Community Action Against Addiction

Community Action Against Addiction, based in Cleveland, OH, provides extensive treatment for substance use disorders through multiple formats such as intensive outpatient, outpatient, and medication-assisted therapies using methadone, buprenorphine, or naltrexone. The center focuses on personalized treatment plans that incorporate methods like cognitive behavioral therapy, anger management, and the Matrix Model. Specialized programs are designed for adult men, adult women, and individuals who have faced intimate partner or domestic violence. Catering to both adult and young adult populations, this facility prioritizes delivering effective care to assist individuals in their recovery journey.

Communicare Inc
Bardstown, KY

Communicare Inc, located in Bardstown, KY, specializes in outpatient services for individuals struggling with substance use disorders and those facing dual diagnoses of addiction and severe mental health challenges. The center employs proven therapeutic methods, including cognitive behavioral therapy, anger management, and brief intervention, within its regular outpatient program. Catering to adolescents, adult men, and adult women, Communicare Inc extends its supportive and effective care to seniors and adults of all genders. Their commitment to personalized treatment strategies and all-encompassing assistance positions Communicare Inc as a premier option for exceptional recovery services in the Bardstown region.

CommQuest Services Inc

CommQuest Services Inc, located in Canton, OH, provides extensive addiction recovery programs for individuals of all ages. Their expertise encompasses withdrawal management, comprehensive substance abuse care, and dual diagnosis treatment. They offer structured intensive outpatient, standard outpatient, and outpatient detoxification options. Through therapeutic approaches such as anger management, cognitive behavioral techniques, and motivational interviewing, patients receive individualized support. The center is notably equipped to serve specific populations including those involved with the justice system, military households, and veterans. CommQuest Services Inc is dedicated to delivering effective, research-supported treatment for both addiction and co-occurring mental health conditions for all genders.

Communicare
Sardis, MS

Situated in Sardis, MS, Communicare is a fully-equipped rehabilitation facility that delivers targeted treatment options for substance abuse and concurrent mental health issues affecting both adults and children. The center offers a variety of services, including intensive outpatient programs, standard outpatient care, and treatments with methadone, buprenorphine, or naltrexone. Emphasizing techniques such as 12-step guidance, anger management, and short-term intervention strategies, Communicare addresses the needs of teenagers and individuals dealing with trauma, intimate partner abuse, and domestic violence. With a commitment to high-quality care, the center formulates personalized treatment strategies for adults and seniors across all gender identities to foster sustainable recovery.

Communities of Recovery Inc

Communities of Recovery Inc in Branson, MO, delivers a variety of scientifically-backed therapies for addiction. The center offers extended, brief, and immediate residential services, utilizing methods including 12-step integration, cognitive behavioral therapy, and contingency management. Featuring tailored programs for adult males, adult females, and younger adults, this establishment serves various demographics. Its dedication to personalized treatment and complete assistance distinguishes this facility, providing excellent care for individuals pursuing recovery. Regardless of your age or gender, Communities of Recovery Inc is dedicated to aiding your path to abstinence.

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Senatobia, MS

Situated in Senatobia, MS, Communicare specializes in outpatient care for adults facing substance misuse and co-occurring mental health issues, as well as for children experiencing significant emotional difficulties. The center offers a variety of services, including outpatient treatment options like methadone or buprenorphine and naltrexone therapies, 12-step programs, anger management, and short-term intervention strategies. With an emphasis on distinct groups such as teens, those who have encountered trauma or domestic violence, and individuals impacted by intimate partner violence, Communicare provides customized support for each person. Catering to adults and seniors of all genders, this establishment is dedicated to offering exceptional, personalized care aimed at fostering enduring recovery.

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Oxford, MS

Communicare, situated in Oxford, MS, is a multifaceted rehabilitation facility that specializes in addressing substance use issues along with accompanying mental health challenges in both adults and children. The center offers a variety of treatment options, such as intensive outpatient programs, standard outpatient services, and medication-assisted therapies like methadone, buprenorphine, and naltrexone. Employing research-backed methodologies, Communicare provides support through 12-step programs, anger management courses, and brief interventions. The center features distinctive programs aimed at adolescents, those affected by intimate partner or domestic violence, and individuals who have experienced trauma. With dedicated services designed for adults and seniors of diverse backgrounds, Communicare is committed to delivering personalized care and support for every individual.

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Holly Springs, MS

Communicare, located in Holly Springs, MS, provides a variety of outpatient treatment options that address issues related to substance use, co-occurring disorders, and traumatic experiences. The center is particularly adept at dealing with intimate partner violence, domestic abuse, and trauma recovery, and it serves adults and seniors of all genders. The treatment methodologies implemented include 12-step programs, anger management, and short-term interventions. With a special emphasis on adolescents and those facing serious mental health challenges, Communicare ensures effective care through outpatient services, including methadone/buprenorphine or naltrexone therapies. This facility is committed to guiding clients through their recovery process with tailored and thorough support.

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Oxford, MS

Situated in Oxford, MS, Communicare provides an array of specialized treatment options designed for both adults and young adults facing challenges related to substance use and concurrent mental health conditions. The center offers a variety of services, including hospital inpatient detoxification and around-the-clock hospital inpatient care, delivering thorough support for those on their journey to recovery. By employing strategies such as 12-step facilitation and anger management, Communicare customizes its treatment plans to align with the specific needs of each client. Additionally, the center features distinct programs for active duty military personnel, as well as for adult men and women, ensuring a tailored approach to care. With an emphasis on high-quality and individualized treatment, Communicare is committed to assisting individuals in achieving enduring sobriety and overall wellness.

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Pittsboro, MS

Situated in Pittsboro, MS, Communicare specializes in providing outpatient care for individuals dealing with substance abuse and co-occurring mental health issues, serving both adults and children. The center focuses on customized treatment plans for those who have faced trauma or domestic violence, fostering a nurturing atmosphere for recovery. Employing methods like 12-step support and anger management techniques, Communicare prioritizes personalized attention for each client. Their offerings include outpatient treatments with methadone/buprenorphine and specific interventions for older adults. Moreover, they feature tailored programs for teenagers, accommodating a broad spectrum of needs. The facility also implements gender-specific services for men and women to ensure a more tailored therapeutic journey.

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Water Valley, MS

Communicare, situated in Water Valley, MS, delivers outpatient care for individuals of all ages struggling with substance use disorders, particularly those also experiencing mental health concerns. The facility distinguishes itself with targeted interventions for teens, survivors of domestic abuse and trauma, and caters to both male and female clientele. Their therapeutic modalities encompass 12-step support, anger resolution techniques, and concise counseling strategies. Prioritizing effective treatment, Communicare also administers outpatient medication-assisted treatment, including methadone, buprenorphine, or naltrexone. Their services are designed to comprehensively address the recovery needs of adults and older adults grappling with addiction and psychological well-being.

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Elizabethtown, KY

Communicare Inc, located in Elizabethtown, KY, provides an extensive selection of outpatient programs aimed at addressing substance use and concurrent mental health challenges in adults, as well as emotional issues in children. Their offerings encompass 12-step support, anger management sessions, and short-term interventions. This center serves diverse groups, such as active duty military members, teenagers, adult males and females, and seniors. Emphasizing personalized care and tailored treatment approaches, Communicare Inc aims to deliver specialized assistance to aid individuals on their journey to recovery.

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Elizabethtown, KY

Communicare Inc, located in Elizabethtown, KY, provides targeted treatment for substance use disorders alongside mental health services for both adults and children. This facility features residential and short-term accommodations and offers methods such as 12-step facilitation, anger management, and brief intervention strategies. The center has distinct programs designed for adult women, particularly those who have experienced intimate partner violence, domestic violence, or sexual abuse. Catering specifically to females, it serves a broad range of individuals, including adults, seniors, and young adults. With a commitment to quality care and personalized treatment plans, this center stands out as a caring option for individuals looking to recover from addiction and traumatic experiences.

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Lebanon, KY

Communicare Inc, located in Lebanon, KY, provides targeted rehabilitation services for adults dealing with substance use challenges alongside mental health disorders, as well as for children facing significant emotional issues. Their treatment options include intensive outpatient, outpatient, and standard outpatient programs that utilize proven methods such as anger management, brief intervention techniques, and cognitive behavioral therapy. The center offers customized programs for adolescents, as well as distinct services for adult men and women, ensuring personalized care for individuals of all ages and genders. Celebrated for its high standards of care and extensive range of services, Communicare Inc is a leading option for those in the Lebanon region seeking effective and empathetic support for addiction recovery.

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Springfield, KY

Communicare Inc, located in Springfield, KY, stands as a prominent rehabilitation facility dedicated to providing outpatient services for individuals struggling with substance use and co-occurring mental health challenges. They cater to a diverse clientele, including adults and young people, and possess expertise in areas such as anger management, cognitive behavioral therapy, and motivational incentives. Communicare Inc offers personalized treatment plans for adults and older adults across the gender spectrum. Their specialized services extend to adolescents, survivors of domestic abuse, and those who have experienced trauma, ensuring thorough assistance for everyone. Regardless of whether one requires ongoing outpatient support or specific methadone/buprenorphine treatment, clients will find a supportive and results-oriented environment at this center.

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Communities of Recovery Inc in Springfield, MO, delivers thorough addiction recovery services, emphasizing extended stays in a residential setting. The center provides structured living environments, including transitional housing, halfway house accommodations, and sober living arrangements, specifically designed for adult men, adult women, and young adults. Through evidence-based methods such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, the program supports individuals of all genders on their path to recovery. Dedicated to the unique needs of young adults, this facility ensures personalized treatment plans for every resident. Communities of Recovery Inc is distinguished by its effective treatment strategies and dedication to fostering sustained abstinence.

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Situated in Willmar, MN, Community Addiction Recovery provides an extensive array of services for individuals dealing with substance use disorders, as well as those facing serious mental health challenges or emotional issues. The center offers various treatment options, including inpatient care, round-the-clock residential support, and guidance based on the 12-step model. Catering to both adult men and women, it also extends its services to those who have faced domestic or intimate partner violence. The facility emphasizes personalized treatment plans, encompassing anger management and short-term interventions, making Community Addiction Recovery a notable choice for high-quality, individualized rehabilitation services.

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Nestled in Carlton, MN, Community Addiction Recovery is dedicated to providing targeted substance use disorder treatment for adult women facing concurrent mental health challenges. The facility features diverse residential care options, encompassing extended stays, shorter programs, and round-the-clock support. Their therapeutic approach emphasizes 12-step facilitation, anger management techniques, and brief intervention strategies, all customized to each person's unique journey. Distinctive offerings are available for adult women, including those who have experienced intimate partner violence, domestic abuse, or sexual assault. Serving a broad age range from young adults to seniors, this center cultivates a secure and encouraging atmosphere for female clients pursuing comprehensive healing and lasting recovery.

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In Anoka, Minnesota, Community Addiction Recovery provides extensive support for individuals struggling with addiction and related mental health challenges. The center specializes in long-term residential care and continuous support, utilizing proven methods like 12-step integration, emotional regulation techniques, and short-term counseling. They offer distinct programs tailored for adult men, adult women, and survivors of sexual trauma, ensuring a personalized approach to recovery. Community Addiction Recovery is dedicated to addressing substance abuse in conjunction with significant mental health concerns, offering a reliable and individualized path to healing for all clients.

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Community and Family Resources, situated in Des Moines, IA, is a complete rehabilitation center for addiction and housing support. They provide outpatient services focusing on 12-step methods, managing anger, and short-term interventions. This establishment assists adult women dealing with combined mental health and substance use issues, including those with a history of trauma. Serving adults, older adults, and younger adults, the center delivers excellent care in a nurturing setting. For those needing expert help with addiction and mental health challenges, Community and Family Resources is committed to guiding individuals toward recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)