NWVCIL Logo
Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6711 results

Compass Health
Raymore, MO

Compass Health, situated in Raymore, MO, is an esteemed rehabilitation facility providing a wide range of treatment options. This center focuses on addressing substance abuse as well as co-occurring disorders for both adults and children. Emphasizing various treatment modalities, including intensive outpatient, outpatient, and standard outpatient care, Compass Health delivers personalized support through methods such as anger management, brief intervention, and cognitive behavioral therapy. A distinctive feature of this center is its dedicated program for those grappling with concurrent mental health and substance abuse issues. Catering to clients of all genders and ages, Compass Health prioritizes high-quality, customized treatment to foster enduring recovery.

Compass Health
Butler, MO

Situated in Butler, MO, Compass Health is an all-encompassing rehabilitation center that specializes in addressing substance use issues along with co-occurring mental health challenges for both adults and children. The center offers a variety of programs including intensive outpatient, outpatient, and treatments involving methadone, buprenorphine, or naltrexone. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, Compass Health is equipped to meet the needs of clients facing intricate issues. The center provides customized care for adults and seniors of all genders, ensuring personalized support and attention. Compass Health is distinguished by its dedication to providing top-tier, evidence-based treatments aimed at fostering long-term recovery and enhancing overall health and wellness.

Compass Health
Osage Beach, MO

In Osage Beach, MO, Compass Health provides a full spectrum of outpatient care for individuals, both young and old, who are struggling with addiction and related mental health challenges. Their expertise includes addressing anger, offering concise interventions, and utilizing cognitive behavioral strategies. Compass Health is particularly adept at supporting those with multiple diagnoses, tailoring treatment for adults and seniors, irrespective of gender. The center delivers outpatient medication-assisted treatment using methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Compass Health is committed to delivering effective, research-backed support to aid in each person's path toward wellness.

Compass Health
Lebanon, MO

Situated in Lebanon, MO, Compass Health provides focused treatment for adults and seniors dealing with substance use issues. Their outpatient program offers consistent therapy employing proven methods such as brief interventions, cognitive behavioral therapy, and motivational interviewing. This center effectively support individuals facing both mental health challenges and substance use disorders, promising an all-encompassing care approach. Emphasizing customized treatment strategies, Compass Health extends its services to both men and women with dedication and skill. For those in need of high-quality addiction rehabilitation in an encouraging setting, Compass Health is a strong choice for personalized recovery solutions.

Compass Health
Raymore, MO

Situated in Raymore, MO, Compass Health specializes in rehabilitation for adults and seniors facing challenges related to substance use disorders alongside severe mental health issues. The center features a range of services including intensive outpatient care, day treatment, and standard outpatient programs, utilizing methods such as anger management, brief interventions, and cognitive behavioral therapy. Emphasizing personalized treatment, Compass Health develops programs to address the distinct needs of every individual. The facility supports clients of all genders, fostering a welcoming atmosphere. For those in search of thorough and quality rehabilitation services, Compass Health is committed to delivering compassionate and effective care.

Compass Health Systems

Compass Health Systems, located in Miami, FL, provides targeted outpatient care for individuals dealing with substance use and co-occurring mental health issues, catering to both adults and children. The center offers various treatment options, including outpatient programs utilizing methadone/buprenorphine and naltrexone. Emphasizing cognitive behavioral therapy, anger management, and brief therapeutic interventions, the facility customizes its approach based on each person's requirements. Additionally, Compass Health Systems has specialized programs designed for clients within the criminal justice system. This center is dedicated to delivering high-quality care to adults and seniors of all genders in a supportive atmosphere that fosters enduring recovery.

Compass Health
Columbia, MO

Compass Health, situated in Columbia, MO, provides a variety of outpatient treatment options focused on substance use issues and co-existing mental health challenges for both adults and children. The center ensures personalized support by employing methods like cognitive behavioral therapy, anger management, and brief intervention strategies. Designed with specific programs for active duty service members as well as male and female adults, Compass Health addresses the unique requirements of its clients. By accommodating both adults and younger individuals, the facility guarantees thorough care for all demographics. Highlighting its commitment to high-quality, tailored treatment, Compass Health remains a reliable choice for individuals seeking effective rehabilitation for addiction.

Compass Health
Higginsville, MO

Compass Health located in Higginsville, MO, specializes in treating substance use disorders alongside co-existing mental health issues for both adults and children. Their offerings comprise intensive outpatient programs, outpatient services, and medications like methadone, buprenorphine, or naltrexone. The center emphasizes anger management techniques, cognitive behavioral therapy, and short-term interventions tailored to clients facing both chronic pain and substance abuse challenges. Serving adults and seniors of any gender, Compass Health focuses on delivering personalized support in a nurturing setting. If you are looking for empathetic and effective treatment options for addiction, this center is committed to guiding you toward sustainable recovery.

Compass Health
Clinton, MO

Compass Health, situated in Clinton, MO, delivers comprehensive outpatient services for adults and youth grappling with substance use and co-occurring mental health concerns. Their day treatment programs are specifically designed for individuals managing both pain and addiction. Employing proven therapeutic methods such as cognitive behavioral therapy and anger management, the center prioritizes personalized, high-quality care for every participant. Compass Health caters to a diverse population, including adults and seniors of all genders, and is distinguished by its all-encompassing approach to simultaneously treating addiction and mental health challenges.

Compass Health
Nevada, MO

Compass Health, situated in Nevada, MO, delivers targeted care for individuals, both young and adult, struggling with substance use and co-occurring mental health conditions. The facility features intensive outpatient, standard outpatient, and medication-assisted treatment programs, including methadone, buprenorphine, or naltrexone. Employing strategies like brief intervention, cognitive behavioral therapy, and motivational interviewing, they are equipped to support those with dual diagnoses. Compass Health extends its services to adults and older adults across all genders, emphasizing personalized attention and proven therapeutic methods. Their mission is to provide high-quality, all-encompassing treatment to guide clients toward lasting recovery.

Compass Health

Compass Health, situated in Salem, MO, stands as a leading outpatient rehabilitation facility dedicated to addressing substance abuse and associated mental health challenges for adults, as well as emotional difficulties in children. The center excels in therapeutic interventions such as anger management, brief intervention strategies, and cognitive behavioral therapy, all delivered with a personalized methodology. Compass Health caters to adults and seniors across all gender identities, offering superior care within a nurturing setting. For those in pursuit of successful addiction recovery, emphasizing individualized attention and scientifically supported methods, this institution is committed to fostering enduring wellness.

Compass Health
Warrensburg, MO

Compass Health in Warrensburg, MO, provides specialized outpatient care for adults and children grappling with substance use disorders and co-occurring mental health conditions. Employing evidence-based techniques such as brief intervention, cognitive behavioral therapy, and motivational interviewing, the center delivers individualized treatment plans designed for clients facing dual diagnoses. Open to adults and seniors across all demographics, Compass Health is committed to meeting the distinct requirements of individuals managing concurrent mental health and addiction challenges. The facility prioritizes high-quality, personalized treatment aimed at fostering sustained recovery and enhanced emotional well-being.

Compass Health
Clinton, MO

Compass Health in Clinton, MO, provides extensive substance use recovery services for adults and young adults. This center is particularly adept at addressing individuals with both substance use disorders and significant mental health challenges or emotional difficulties. Their treatment offerings include intensive outpatient, outpatient, and standard outpatient programs, employing proven methods such as anger management, cognitive behavioral therapy, and motivational interviewing. A distinguishing feature of Compass Health is its specialized care for individuals with trauma histories, dual diagnoses of mental and substance use disorders, and those managing concurrent pain and addiction. Offering gender-specific support, Compass Health is dedicated to delivering high-quality rehabilitation and assistance for those pursuing sobriety.

Placeholder image
Columbia, MO

Situated in Columbia, MO, Compass Health stands out as a leading rehabilitation center dedicated to addressing substance abuse and co-occurring disorders in both adults and children. The facility features a range of treatment options, including intensive outpatient, outpatient, and standard outpatient programs, employing proven methods like cognitive behavioral therapy and motivational interviewing. Compass Health offers targeted programs for adult women, individuals who have experienced trauma, and those facing dual mental health challenges. Designed for adults, seniors, and young adults, this women-centered facility commits to delivering exceptional care for individuals in need of thorough and effective rehabilitation services.

Placeholder image
Columbia, MO

Situated in Columbia, MO, Compass Health provides a variety of research-supported treatment options for substance abuse and concurrent mental health challenges in both adults and children. Individuals can participate in intensive outpatient care, day outpatient programs, and partial hospitalization. The facility excels in offering services such as anger management, brief interventions, and cognitive behavioral therapy. Tailored programs are available specifically for teenagers, those facing dual diagnoses, and individuals dealing with both pain and substance dependence. Compass Health is dedicated to serving adults and older adults of all genders, emphasizing quality care and customized treatment strategies to meet each client's unique requirements.

Placeholder image
Owensville, MO

Situated in Owensville, MO, Compass Health delivers a wide variety of outpatient services aimed at helping individuals recover from substance use disorders and related mental health challenges. This center focuses on detoxification, treatment for substance use issues, and assists those dealing with concurrent pain and addiction. Emphasizing brief interventions, cognitive behavioral therapy, and motivational interviewing, Compass Health customizes treatment strategies to address the specific needs of each individual. The facility offers specialized programs for those who have faced trauma and for individuals with co-occurring mental health difficulties. Catering to both adults and youth, the center provides outpatient detox services and treatments using methadone/buprenorphine or naltrexone, welcoming clients from all genders.

Placeholder image
Odessa, MO

Situated in Odessa, MO, Compass Health delivers extensive outpatient rehabilitation solutions for individuals grappling with substance use and co-occurring mental health conditions, serving both adults and adolescents. The center customizes treatment plans, incorporating outpatient methadone/buprenorphine therapy alongside cognitive behavioral interventions. Unique offerings address the needs of clients with past trauma, concurrent pain and substance use issues, and those benefiting from short-term support. Prioritizing motivational interviewing and personalized care, Compass Health is committed to providing high-quality support for all genders and age groups. For those pursuing scientifically proven methods within a nurturing setting, this establishment is devoted to facilitating the journey toward recovery.

Placeholder image

Situated in Eldon, MO, Compass Health excels as a premier rehabilitation establishment, delivering expert care for individuals battling substance use disorders and concurrent mental health conditions, encompassing adults and youth. They offer a spectrum of treatment approaches, including outpatient services and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center's holistic approach encompasses crucial elements like brief intervention strategies, relapse prevention planning, and dedicated counseling for substance use disorders. Compass Health distinguishes itself through its customized treatment plans, specifically addressing the needs of clients who have undergone trauma, those managing co-occurring pain and substance use issues, and individuals with dual diagnoses. Catering to both male and female patients of all ages, the facility is committed to providing superior, personalized care aimed at fostering recovery and overall well-being.

Placeholder image
Fulton, MO

Compass Health in Fulton, MO provides comprehensive, research-backed recovery services for individuals of all ages facing addiction and coinciding mental health challenges. Their program offerings include intensive outpatient, outpatient, and standard outpatient care, employing proven methods like anger management, brief intervention, and cognitive behavioral therapy. They have specific support for those with dual diagnoses, chronic pain and addiction, and individuals navigating legal issues. Compass Health welcomes both men and women, dedicating themselves to excellent care and personalized strategies that foster lasting recovery and improved health.

Placeholder image
Jefferson City, MO

Compass Health in Jefferson City, MO, delivers extensive addiction recovery services for adults and youth facing concurrent mental health challenges. The center features robust intensive outpatient and outpatient options, notably including specialized methadone and buprenorphine therapies. Emphasizing anger management, brief intervention, and cognitive behavioral techniques, Compass Health supports those with co-occurring pain and addiction. Offering gender-specific programming, the facility ensures high-quality support for individuals pursuing sustained sobriety. Compass Health is committed to facilitating your journey toward a more robust well-being within a nurturing setting.

Placeholder image

Compass Health Network Inc, located in Sedalia, MO, provides targeted outpatient services for adults and children dealing with substance use issues and concurrent mental health conditions. The center offers a range of therapies, including anger management, cognitive behavioral therapy, and short-term interventions tailored to meet the specific needs of individuals. It features outpatient treatment options using methadone/buprenorphine or naltrexone, ensuring holistic support for clients facing dual diagnoses. With an emphasis on serving adults and seniors across all genders, Compass Health Network Inc is recognized for its personalized strategies and dedication to delivering high-quality care for those on the path to recovery from substance use and mental health difficulties.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)