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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Community and Family Resources

Situated in Fort Dodge, IA, Community and Family Resources provides a wide array of detox and substance abuse rehabilitation services. Emphasizing an all-encompassing strategy, this center delivers intensive outpatient, outpatient, and standard outpatient treatment options. It specializes in programs designed for teenagers, adult males, and adult females, serving clients of all genders and various age groups, from adolescents to adults. Community and Family Resources is distinguished by its customized treatment plans, committed to delivering high-quality support for individuals pursuing recovery from addiction.

Community Partners Integrated

Community Partners Integrated, located in Tucson, AZ, provides a variety of treatment options including intensive outpatient, outpatient, and standard outpatient programs for those dealing with substance use and co-occurring disorders in both adults and children facing significant mental health challenges. The facility emphasizes key areas such as Anger Management, Brief Intervention, and Cognitive Behavioral Therapy, ensuring that care is customized to meet the unique requirements of every client. Catering to adults and seniors across all genders, the center is known for its all-encompassing methodology and dedication to delivering high-quality care. Individuals seeking assistance for substance use or dual diagnoses can expect personalized support and expert guidance at Community Partners Integrated.

Community Renewal Team

The Community Renewal Team in Hartford, CT, provides targeted substance abuse services for adults dealing with co-occurring mental health conditions or children with emotional disturbances. Their offerings encompass intensive outpatient and standard outpatient care, along with medication-assisted treatment options like methadone, buprenorphine, and naltrexone. Employing therapeutic strategies such as anger management, cognitive behavioral therapy, and brief intervention, the center supports adult men and women, including survivors of domestic violence. This establishment offers a full spectrum of care for adults and young adults of any gender, prioritizing personalized attention and effective treatment results.

Community Mental Health Center Inc

Situated in Lawrenceburg, IN, Community Mental Health Center Inc specializes in addressing substance use and co-occurring disorders in both adults and children. The center offers a range of therapeutic programs, including intensive outpatient, outpatient, and day treatment options. It employs various methodologies, such as 12-step facilitation, anger management, and brief intervention strategies. Committed to personalized care, the facility serves individuals of all genders, including adults and seniors. Community Mental Health Center Inc is notable for its diverse treatment alternatives and dedication to providing exceptional support for individuals pursuing recovery from addiction and mental health issues.

Community and Family Resources

Situated in Iowa City, IA, Community and Family Resources presents an extensive array of treatment options to tackle substance use issues, dual mental health diagnoses, and emotional challenges for both adults and children. The facility offers outpatient services, transitional living, and sober housing solutions. Employing evidence-based methodologies like cognitive behavioral therapy and anger management, the center customizes treatment plans for each person. With a commitment to personalized care, it serves male and female clients across various age groups. Community and Family Resources is focused on delivering high-quality support to assist clients in attaining sustainable recovery.

Community and Family Resources

Situated in Iowa City, IA, Community and Family Resources delivers a wide array of services for those dealing with addiction. This center features intensive outpatient programs, general outpatient care, and specialized initiatives aimed at young people. With a focus on substance abuse and related mental health issues, the facility also provides transitional housing and sober living arrangements. Incorporating methods such as 12-step facilitation and anger management, the center serves individuals of all ages and genders. Community and Family Resources is committed to offering high-quality support and care to those pursuing recovery from addiction in a supportive environment.

Community Mental Health Center Inc

Community Mental Health Center Inc located in Lawrenceburg, IN, provides targeted support for individuals dealing with substance abuse and simultaneous mental health issues for both adults and youth. The center offers a variety of programs, including intensive outpatient and outpatient care, as well as day treatment options. Their approach features 12-step facilitation, anger management strategies, and brief intervention methods. Customized programs are created for adults and seniors across all genders, demonstrating the center's commitment to exceptional care and individualized service. For those seeking reliable, evidence-based treatment in a compassionate setting, this facility's extensive services and focus on personal requirements make it an essential aid for anyone striving for recovery.

Community Mental Health Center Inc

Community Mental Health Center Inc in Vevay, IN provides extensive care for individuals struggling with substance abuse. This facility specializes in treating adults who also experience serious mental health conditions, as well as children with emotional disturbances. Their treatment offerings include outpatient and intensive outpatient services, integrating methodologies like 12-step facilitation, anger management, and brief interventions. Community Mental Health Center Inc is committed to offering personalized care, adapting treatment strategies to the specific needs of adults and seniors across all gender identities. Their dedication to developing customized recovery plans ensures a unique approach for every client. For those looking for scientifically supported treatment within a nurturing setting, this center is devoted to delivering excellent support.

Community Services Associates

Community Services Associates in Portage, WI, provides outpatient care for adults struggling with addiction and co-occurring mental health challenges. They have distinct programs designed for young people, men, and women, utilizing proven methods like cognitive behavioral therapy and anger management. This facility offers personalized treatment, including outpatient medication management with methadone, buprenorphine, or naltrexone, alongside general outpatient support. Community Services Associates is dedicated to delivering high-quality, individualized recovery plans for adults and seniors.

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Community and Family Resources, situated in Des Moines, IA, is a complete rehabilitation center for addiction and housing support. They provide outpatient services focusing on 12-step methods, managing anger, and short-term interventions. This establishment assists adult women dealing with combined mental health and substance use issues, including those with a history of trauma. Serving adults, older adults, and younger adults, the center delivers excellent care in a nurturing setting. For those needing expert help with addiction and mental health challenges, Community and Family Resources is committed to guiding individuals toward recovery.

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Situated in Des Moines, IA, Community and Family Resources provides exceptional treatment for substance use disorders and specialized support for adults experiencing co-occurring substance use and significant mental health challenges, as well as for children dealing with severe emotional issues. This center offers both residential and short-term residential programs that incorporate customized approaches including 12-step methods, anger management strategies, and focused interventions. With a strong emphasis on tailored care, the facility serves adults and young adults across all gender identities. Community and Family Resources is distinguished by its dedication to quality care and individualized treatment plans, positioning it as a leading option for individuals in need of extensive rehabilitation services.

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Situated in Brookville, IN, Community Mental Health Center Inc delivers a wide-ranging substance use rehabilitation program for both adults and children dealing with serious mental health issues alongside addiction. The center features intensive outpatient programs, outpatient day treatment, and partial hospitalization options, employing techniques that include 12-step facilitation, anger management, and brief interventions. Emphasizing personalized care, the facility serves adults and elderly individuals of all genders. Community Mental Health Center Inc is recognized for its customized treatment strategies and dedication to high-quality care, establishing itself as a leading option for individuals in need of effective and individualized rehabilitation solutions.

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Situated in Batesville, IN, Community Mental Health Center Inc delivers focused rehabilitation services tailored for both adults and children dealing with substance use issues and significant mental health challenges. This center offers a range of treatment programs, including intensive outpatient, outpatient, and partial hospitalization, utilizing methods such as 12-step facilitation, anger management, and brief intervention strategies. Emphasizing personalized care, the facility serves adults and seniors of all genders. Community Mental Health Center Inc is distinguished by its wide-ranging treatment offerings and dedication to high-quality care, positioning it as an essential resource for individuals in need of customized rehabilitation support.

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Situated in West Harrison, IN, the Community Mental Health Center Inc delivers a wide range of rehabilitation services aimed at adults and older adults facing challenges related to substance abuse and concurrent mental health disorders. The center provides multiple treatment options, including intensive outpatient programs, day treatment, and partial hospitalization, prioritizing personalized attention. Various therapeutic strategies such as 12-step facilitation, anger management, and brief interventions are employed to meet the specific requirements of each individual. With specialized programs designed for both men and women, this facility creates a nurturing atmosphere for all clients. If you're in search of effective support for addiction and mental health issues, this center is committed to guiding you towards sustainable recovery.

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Community Mental Health Center Inc, situated in Batesville, IN, delivers a full spectrum of care for individuals struggling with addiction and accompanying mental health challenges, catering to both younger and adult populations. Their services include robust intensive outpatient options, general outpatient care, and partial hospitalization programs. Emphasizing a holistic approach that incorporates 12-step principles, emotional regulation strategies, and short-term counseling techniques, the center prioritizes personalized treatment plans. Open to adults and seniors regardless of gender, Community Mental Health Center Inc is distinguished by its customized recovery pathways, offering effective support for everyone on their journey to wellness.

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Situated in Safford, AZ, Community Partners Integrated provides extensive treatment for substance use disorders along with targeted support for dual diagnoses involving substance use and severe mental health issues in adults, as well as serious emotional challenges in children. The center emphasizes intensive outpatient programs, diversified outpatient services, and medicated treatments using methadone, buprenorphine, or naltrexone. Utilizing effective methodologies such as cognitive behavioral therapy, anger management, and brief interventions, the facility designs personalized programs for adults and seniors of every gender, guaranteeing customized assistance for each patient. Community Partners Integrated is distinguished by its dedication to high-quality care and individualized treatment strategies.

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Community Programs Inc, located in Waterford, MI, provides extended residential and round-the-clock support for detoxification and treatment of substance use disorders. Their customized programs feature 12-step methods, anger management training, and brief intervention strategies. This center focuses on assisting adult males, young adults, and those facing both mental health and substance use challenges. Additionally, they serve clients involved with criminal justice proceedings. With distinct programs tailored for men and women, this facility offers personalized care that addresses a variety of needs. Community Programs Inc is committed to delivering high-quality assistance and support for individuals pursuing thorough and impactful addiction recovery.

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Community Programs Inc, situated in Waterford, MI, delivers thorough addiction treatment for adults and young adults. Their services encompass detoxification and substance use treatment, available through extended residential stays, outpatient care, and outpatient methadone/buprenorphine or naltrexone options. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, the facility supports adult men and women, including those managing co-occurring mental health and substance use challenges. The center's specialized offerings provide personalized care, ensuring high-quality treatment and assistance for all clients pursuing sobriety.

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Situated in Oceanside, California, the Community Research Foundation provides exceptional residential treatment for substance use disorders. Emphasizing methods such as 12-step facilitation, anger management, and brief intervention techniques, the facility serves both adult men and women, including those affected by domestic violence or intimate partner issues. Customized programs are designed for adults and young adults, offering gender-specific care. The center's dedication to high-quality, personalized treatment distinguishes it as an excellent option for individuals looking for thorough rehabilitation services within a nurturing atmosphere.

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Nestled in Chula Vista, California, Community Research Foundation provides outpatient services for individuals of all ages facing challenges with substance abuse and co-occurring mental health disorders. Their approach integrates proven therapeutic modalities, including cognitive behavioral therapy and motivational interviewing, to equip clients with relapse prevention tools essential for sustained well-being. The center excels in supporting individuals with dual diagnoses and young adults, offering gender-specific programs. Prioritizing personalized care, Community Research Foundation is committed to empowering adults and young adults in their journey toward recovery from addiction and mental health issues.

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Situated in Carlyle, IL, the Community Resource Center provides outpatient treatment for substance use disorders and focused support for individuals dealing with concurrent mental health challenges. Employing methods such as cognitive behavioral therapy and anger management, the center delivers ongoing outpatient programs for both adults and seniors. Tailored initiatives are available for clients who have faced trauma, those with dual diagnoses of mental health and substance use disorders, as well as individuals linked to the criminal justice system. The facility serves a diverse clientele, emphasizing a commitment to high-quality care and assistance for those in pursuit of thorough rehabilitation options.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)