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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Cornerstone Adult Outpatient

Cornerstone Adult Outpatient, located in Santa Ana, CA, provides a range of intensive outpatient services, standard outpatient programs, and day treatment options for individuals battling substance use disorders. The center features specialized programs aimed at active duty military personnel, as well as tailored treatments for adult men and women, addressing the needs of a wide demographic. Incorporating strategies such as 12-step facilitation, cognitive-behavioral therapy, and brief interventions, this facility delivers thorough and customized care for adults and young adults, regardless of gender. By emphasizing personalized treatment plans within a nurturing environment, Cornerstone Adult Outpatient is committed to offering high-quality support for those on their path to recovery from addiction. Rely on Cornerstone Adult Outpatient for compassionate, evidence-based treatment in an inviting atmosphere.

Cornerstone Healing Center

Cornerstone Healing Center, located in Scottsdale, AZ, provides an all-encompassing program for substance use rehabilitation alongside targeted support for those experiencing co-occurring mental health issues. The center offers both residential and short-term residential treatment options specifically designed for adults and young adults. Their methodology incorporates 12-step support, strategies for managing anger, and short intervention methods. With dedicated programs available for active duty military personnel, men, and women, the center addresses a wide range of requirements. By serving both genders, Cornerstone Healing Center emphasizes exceptional care and personalized treatment to assist clients in their recovery journey.

Cornerstone Healing Center

Cornerstone Healing Center in Scottsdale, AZ, provides extensive support for individuals battling addiction and those needing stable living arrangements. Their expertise lies in addressing dual diagnoses, treating substance abuse concurrently with severe mental health conditions in adults and significant emotional challenges in youth. Their treatment offerings include robust outpatient programs like intensive outpatient, day treatment, and partial hospitalization. Utilizing methods such as 12-step integration, anger management techniques, and brief intervention strategies, Cornerstone Healing Center delivers personalized recovery plans for adult men, women, and young adults. They also offer specialized support for active military members. Committed to delivering high-caliber services to both adult men and women, the center is devoted to guiding clients toward lasting recovery.

Cornerstone of Medical Arts Center

Cornerstone of Medical Arts Center, located in Fresh Meadows, NY, provides extensive treatment options for substance use disorders and specialized support for those facing both substance abuse and significant mental health issues. The center features both residential and short-term residential programs designed for adults and young adults. Emphasizing 12-step programming, anger management techniques, and brief intervention strategies, it serves adult men, women, and individuals who have undergone trauma. The facility prioritizes personalized care for all clients, fostering a compassionate and encouraging atmosphere essential for successful recovery.

Cornerstone of Recovery

Cornerstone of Recovery, located in Louisville, TN, provides an extensive array of services for those struggling with addiction. The center specializes in detox programs, treatment for substance abuse, and offering targeted support for adults facing both substance use issues and serious mental health conditions, as well as addressing emotional challenges in children. With a variety of treatment options such as intensive outpatient care, long-term residential stays, and standard outpatient programs, the center meets a wide range of individual needs. Applying techniques like 12-step principles, anger management sessions, and short-term interventions, Cornerstone of Recovery prioritizes personalized treatment. It also features dedicated programs for active military members, along with services specifically for adult men and women. This facility is committed to providing high-quality, effective rehabilitation care for adults and young adults of every gender.

Cornerstone of Rhinebeck

Situated in Rhinebeck, NY, the Cornerstone of Rhinebeck delivers a full range of addiction recovery services. Focusing on detoxification and substance abuse rehabilitation, the center offers residential options in different lengths of stay, including both short-term solutions and around-the-clock support. Employing research-backed methods such as 12-step programming, anger management techniques, and brief interventions, this facility provides customized programs for adult males, adult females, and LGBTQ clientele, addressing a wide spectrum of requirements. Aiming to assist both adults and young adults of all genders, Cornerstone of Rhinebeck emphasizes high-quality care and personalized treatment plans to encourage sustainable recovery.

Cornerstone of Rhinebeck

Situated in Rhinebeck, NY, Cornerstone of Rhinebeck specializes in treating substance use disorders in a tranquil residential atmosphere. This facility serves adult men and women, including those with a history of trauma, and offers customized programs tailored to individual needs. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, the center provides thorough care for its clients. Cornerstone of Rhinebeck features both short-term and 24-hour residential options for adults and young adults, fostering a nurturing environment for healing and recovery. With a strong commitment to high-quality care, this facility serves as a vital source of hope for individuals seeking effective treatment for addiction.

Cornerstone of Southern California

Situated in Tustin, CA, Cornerstone of Southern California delivers a wide array of services for addiction recovery. This facility emphasizes detoxification and treatment for substance use, offering long-term residential care, residential detox, and round-the-clock support. It employs various therapeutic approaches, including 12-step facilitation, brief intervention, and cognitive behavioral therapy, addressing the needs of adult men and women, particularly those facing co-occurring mental health issues alongside substance use disorders. Cornerstone of Southern California provides high-quality, individualized treatment programs tailored to the needs of adults and young adults of all genders.

Cottonwood Tucson

Cottonwood Tucson, located in Tucson, AZ, delivers a wide array of services designed for the treatment of addiction, aimed at both adults and young adults. The center specializes in detox services, substance use treatment, transitional living options, halfway houses, and sober housing, with offerings that include intensive outpatient programs, long-term residential care, and outpatient treatment. Cottonwood Tucson has unique programs tailored for adult men, adult women, and active duty military members, employing methods like 12-step programs, anger management, and brief interventions to meet the specific needs of individuals. The facility prioritizes high-quality care with gender-specific services aimed at males and females, positioning itself as an essential resource for those in need of personalized addiction rehabilitation support.

Council Bluffs Comprehensive Trt Ctr

Council Bluffs Comprehensive Trt Ctr, located in Council Bluffs, IA, delivers outpatient substance abuse treatment and detox services designed for adults and young adults. Their specialized offerings include anger management, cognitive behavioral therapy, and brief intervention strategies. Dedicated to providing excellent care, this center features distinct programs for active military duty members, adult males, and adult females. Treatment modalities encompass outpatient care with methadone, buprenorphine, or naltrexone. The facility is equipped to serve both male and female individuals, promoting a thorough and welcoming approach to overcoming addiction.

Council for Alcohol/DA Servs Inc

Council for Alcohol/DA Servs Inc in Chattanooga, TN, provides comprehensive addiction recovery support. They offer a spectrum of services including detox, substance use therapy, and housing options like transitional living, halfway houses, and sober living environments. Treatment modalities encompass intensive outpatient, long-term residential, and standard outpatient programs. Their therapeutic interventions include 12-step facilitation, anger management, and brief intervention strategies. This facility assists adult men and women, including those facing co-occurring mental health and substance use challenges, and serves young adults of all genders. Council for Alcohol/DA Servs Inc is committed to delivering effective care for individuals pursuing sobriety.

Cornerstone Services Inc

Cornerstone Services Inc, located in Joliet, IL, provides an array of tailored treatment options for both adults and young adults who are facing challenges related to substance abuse and associated mental health issues. The center features intensive outpatient, outpatient, and standard outpatient programs, employing proven methods such as cognitive behavioral therapy and anger management techniques. Specialized programs are available for those who have suffered from trauma as well as individuals dealing with dual diagnoses. Committed to delivering high-quality care and personalized treatment plans, Cornerstone Services Inc serves both male and female clients in need of holistic support as they work towards recovery.

Counseling Associates Inc

Counseling Associates Inc, located in Conway, AR, provides outpatient services for adults battling substance use issues alongside mental health disorders. This facility employs a range of therapeutic methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. Additionally, it offers customized programs for teenagers as well as individuals involved in the criminal justice system. Focusing on outpatient treatments using methadone, buprenorphine, or naltrexone, the center serves adults and older adults across all genders. With a dedication to personalized care and research-supported methods, it aims to deliver effective support for those working towards recovery from addiction and mental health difficulties.

Coshocton Cnty Drug/Alc Council Inc

Coshocton Cnty Drug/Alc Council Inc, situated in Coshocton, OH, delivers extensive support for individuals overcoming addiction. The center offers a range of recovery accommodations, including transitional and sober living environments. It also addresses the complexities of dual diagnoses, providing integrated care for co-occurring mental health and substance use challenges. Recognizing varied circumstances, specialized tracks are available for young people, those who have experienced trauma, and individuals navigating the legal system. Treatment modalities encompass intensive outpatient services and outpatient medication-assisted treatment with methadone or buprenorphine. Employing evidence-based practices like 12-step facilitation, cognitive behavioral therapy, and anger management, Coshocton Cnty Drug/Alc Council Inc offers individualized recovery journeys for adults and seniors, irrespective of gender.

Counseling and Recovery Services of OK

Situated in Tulsa, OK, Counseling and Recovery Services of OK provides extensive programs for substance use treatment along with transitional housing options. The center focuses on addressing both substance use problems and significant mental health challenges in adults, as well as emotional issues in children. Offering outpatient care and tailored programs for pregnant or postpartum women, this facility employs methods such as cognitive behavioral therapy, community reinforcement, and contingency management. Catering to adults and seniors of all genders, the center is committed to delivering high-quality support for those on their journey to recovery in an encouraging setting.

Counseling Associates Inc

Situated in Russellville, AR, Counseling Associates Inc delivers extensive outpatient services for individuals struggling with substance use disorders, including both adults and children facing significant mental health challenges. The center features targeted programs for those with co-occurring issues, employing research-backed methods such as cognitive behavioral therapy and motivational interviewing. Clients have access to outpatient treatment options like methadone/buprenorphine or naltrexone, along with services for preventing relapse. The facility places a strong emphasis on serving adolescents, seniors, and clients involved with the criminal justice system, offering personalized care for every individual. Both male and female clients benefit from specialized, high-quality treatment tailored to their specific needs at this esteemed rehabilitation center.

Counseling Associates Inc

Counseling Associates Inc, situated in Morrilton, AR, provides extensive outpatient services for individuals dealing with substance abuse and co-occurring mental health disorders, catering to both adults and children. Employing evidence-supported methodologies such as motivational interviewing and cognitive behavioral therapy, the center delivers tailored treatment for men, women, and older adults. Emphasizing personalized treatment strategies and relapse prevention, this facility also serves clients involved in the criminal justice system. In addition, it offers outpatient treatment options with methadone, buprenorphine, and naltrexone to support those on their journey to recovery in a nurturing setting.

Counseling Associates Inc

Counseling Associates Inc located in Clinton, AR, provides outpatient treatment for substance use issues affecting both adults and children with significant mental health challenges. The center emphasizes the use of cognitive behavioral therapy, motivational interviewing, and strategies for relapse prevention. It also offers programs specifically designed for clients involved in the criminal justice system and those with forensic considerations, ensuring a focus on specialized care for unique needs. Catering to both adult and older adult populations of any gender, the facility provides outpatient services including methadone/buprenorphine or naltrexone treatment alongside standard outpatient offerings. Renowned for its high-quality care and holistic approach, this center is dedicated to effectively managing co-occurring disorders within a nurturing environment.

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Cornerstone Behavioral Healthcare LLC, located in Bangor, ME, stands as a leading outpatient center for addiction recovery. They provide a range of specialized services, including medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. Additional offerings encompass anger management, brief intervention strategies, and cognitive behavioral therapy. The center emphasizes a person-centered philosophy, serving adult and senior individuals across all demographics. Cornerstone Behavioral Healthcare LLC fosters a secure and supportive setting for those pursuing effective, customized support in their path to sobriety. Their commitment to excellence and scientifically-backed methods ensures comprehensive client support throughout the recovery process.

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Nestled in Fort Pierce, FL, Counseling and Recovery Center Inc provides targeted rehabilitation programs for both adults and young adults coping with substance use issues. The center features various treatment formats, including intensive outpatient services, standard outpatient care, and structured day programs. Emphasizing techniques such as 12-step support, anger management, and brief intervention strategies, this facility serves adult clients of all genders, including individuals who have faced domestic violence or intimate partner violence. With a commitment to personalized care and tailored programs addressing the unique needs of different age groups and genders, the center strives to deliver effective and holistic support for those on their path to recovery from substance use disorders.

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Counseling Associates Inc, situated in Marshall, AR, delivers outpatient care for adults grappling with substance misuse and co-occurring mental health conditions. Their expertise encompasses cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. The center provides standard outpatient services alongside medication-assisted treatment options like methadone, buprenorphine, or naltrexone. They offer specialized programming for individuals with dual diagnoses, ensuring a holistic approach to recovery. Counseling Associates Inc caters to adult and senior clients, accommodating all genders, and provides a gender-specific setting. For those in search of robust addiction treatment that integrates mental health support, this facility presents dedicated services designed to meet individual requirements.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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