Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.
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Located in Tucson, AZ, COPE Community Services Inc delivers both intensive outpatient and standard outpatient treatment for substance use issues aimed at adults and young adults. This center focuses on individuals with dual mental health challenges, offering therapy rooted in cognitive behavioral methods and strategies for managing anger. Their program incorporates contingency management to encourage successful recovery. Designed specifically for those with trauma backgrounds, they also tackle substance use disorders. Featuring distinct programs for male and female participants, COPE Community Services Inc ensures holistic support for those facing addiction and mental health obstacles.

Situated in Copper Center, AK, the Copper River Native Association provides outpatient treatment options for those dealing with substance use issues. The center offers therapies that include methadone/buprenorphine and naltrexone, along with standard outpatient services. Their approach features techniques like 12-step programs, anger management, and brief intervention. Catering to adolescents, as well as adult men and women, this facility serves individuals of all ages and backgrounds. The Copper River Native Association is dedicated to delivering individualized care combined with evidence-based methods to assist clients on their path to recovery.

Situated in Avondale, AZ, Copper Springs specializes in providing extensive treatment for addiction affecting both adults and young individuals. The center features hospital-based inpatient detox and addresses issues related to substance use disorders, offering specialized support for those with simultaneous mental health conditions. Employing research-supported strategies like cognitive behavioral therapy and motivational incentives, the facility is attentive to the specific requirements of active military personnel, teenagers, and families associated with the military. With programs designed for both male and female adults, as well as seniors, Copper Springs is dedicated to delivering effective care and assistance for those on the path to recovery from substance abuse and mental health difficulties.

Core Recovery LLC, located in Phoenix, AZ, specializes in treating substance use disorders for both adults and children who also face mental health challenges. The center offers a variety of treatment options, including intensive outpatient programs, outpatient care, and day treatment sessions, all grounded in evidence-based practices such as cognitive behavioral therapy and motivational interviewing. Catering to both men and women, as well as those who have endured trauma, Core Recovery LLC provides personalized programs for adults and youth of all ages and genders. Individuals looking for either short-term interventions or extensive outpatient treatment will discover effective solutions available at this center.

The Cornell Scott Hill Health Center located in New Haven, CT, offers extensive outpatient treatment for adults dealing with substance use issues alongside significant mental health conditions, as well as support for children facing serious emotional challenges. The center provides options such as methadone, buprenorphine, or naltrexone therapy and emphasizes programs in anger management, brief interventions, and cognitive behavioral therapy. Specialized services are designed for adult men and women, including those affected by intimate partner or domestic violence. This center serves both adults and young adults, ensuring that care is tailored to the gender-specific needs of its clients. Committed to delivering high-quality, personalized treatment, the Cornell Scott Hill Health Center fosters a nurturing atmosphere for individuals on their journey to recovery.

The Cornell Scott Hill Health Center, situated in Ansonia, CT, delivers extensive outpatient services for individuals facing substance use challenges, including adults and young adults. The center focuses on treating those with co-occurring disorders relating to substance use and significant mental health concerns, alongside addressing emotional issues in children. It employs a variety of evidence-based techniques such as cognitive behavioral therapy, anger management, and motivational interviewing. The facility also features specialized programs designed for adult men and women, as well as individuals impacted by intimate partner violence, ensuring personalized treatment for every patient. The center provides outpatient options for methadone/buprenorphine or naltrexone therapy, accommodating both men and women seeking effective rehabilitation solutions.

COPE Community Services Inc, located in Tucson, AZ, specializes in treating adults facing substance use issues alongside severe mental health disorders and offers assistance to children dealing with significant emotional challenges. The center features a range of programs, including intensive outpatient, standard outpatient, and treatment options using methadone, buprenorphine, or naltrexone. Through methods such as anger management, cognitive behavioral therapy, and contingency management, this center addresses the needs of clients who have encountered trauma as well as those with combined mental health and addiction challenges. COPE Community Services Inc provides effective care and resources for adults and young adults of all genders in their journey toward recovery.

COPE Community Services Inc, located in Tucson, AZ, is dedicated to providing targeted addiction recovery services for adults and young adults facing concurrent mental health challenges. This center features robust intensive outpatient and outpatient offerings, which include medication-assisted treatment with methadone or buprenorphine. Their methodology is grounded in proven techniques like cognitive behavioral therapy and anger management, further enhanced by specialized interventions for individuals who have experienced trauma or have dual diagnoses, guaranteeing holistic support. COPE Community Services Inc is distinguished by its individualized treatment strategies and its unwavering dedication to assisting all clients, male and female alike, in their journey toward lasting sobriety.

COPE Community Services Inc, located in Tucson, AZ, provides a variety of research-backed therapies for individuals facing substance abuse issues as well as co-existing mental health conditions, applicable to both adults and youth. The facility offers several treatment modalities, including intensive outpatient services, outpatient care, and medication-assisted therapies. Emphasizing anger management, cognitive behavioral approaches, and motivational strategies, the programs are designed to assist those with trauma backgrounds and dual diagnoses. This center is committed to offering personalized, compassionate care to individuals of all genders, supporting them as they work towards recovery.

CORE Health in Longview, WA, delivers comprehensive outpatient and intensive outpatient substance use disorder recovery services. They cater to adults and young adults grappling with co-occurring serious mental health conditions. The center offers tailored support for active duty military, adult men, and women. Their therapeutic modalities encompass 12-step facilitation, anger management techniques, and brief intervention strategies. Emphasizing personalized recovery plans, CORE Health provides outpatient medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Serving both genders, CORE Health is dedicated to providing high-quality rehabilitative care, customized to meet the distinct requirements of every patient.

Copes Outpatient, situated in Pendleton, OR, provides a wide array of treatment options for substance use disorders, including intensive outpatient and outpatient services, alongside methadone, buprenorphine, or naltrexone treatments. This center emphasizes a range of therapeutic techniques, such as 12-step programs, anger management, and brief interventions. It primarily serves adult men and women, as well as individuals who have faced intimate partner or domestic violence, ensuring a service tailored to a varied clientele. Copes Outpatient is committed to offering high-quality, personalized support to assist both adults and youth in their recovery processes.

Coras Behavioral Health and Wellness, located in Seaford, DE, specializes in the treatment of substance use disorders and co-occurring mental health issues for both adults and children. The facility offers a variety of programs, including intensive outpatient therapy, outpatient services, and options for medication-assisted treatment. Emphasizing approaches such as 12-step facilitation, anger management, and brief interventions, Coras Behavioral Health and Wellness customizes its programs to address the unique needs of each client. Understanding the significance of tailored care, they provide gender-specific treatment for male and female clients of all ages. Their dedication to high-quality, individualized care positions them as a reliable choice for those in need of thorough rehabilitation solutions.

Coras Wellness and Behavioral Health in Millsboro, DE, provides comprehensive behavioral health services for individuals facing substance use challenges and co-occurring mental health conditions, serving both youth and adults. Their structured outpatient and intensive outpatient programs encompass medication-assisted treatment options like methadone and buprenorphine. The center also integrates therapeutic modalities such as 12-step support, anger management techniques, and brief intervention strategies. Coras Wellness and Behavioral Health is dedicated to creating personalized recovery plans for adult men and women, including those with a history of trauma, and young adults of all genders, fostering enduring mental well-being and sobriety.

CORE Medical Clinic Inc. in Sacramento, California, provides outpatient services for individuals struggling with substance use disorders. The clinic employs proven methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention techniques. Services are available for adults, young people, and expectant or new mothers. The center also offers tailored programs for individuals facing co-occurring mental health and substance use issues, as well as those navigating the legal system. Both male and female clients can access outpatient treatment, which may include medication-assisted treatment with methadone, buprenorphine, or naltrexone, in addition to standard outpatient support. CORE Medical Clinic is committed to delivering high-quality, personalized care to assist individuals on their journey to recovery.

COPE Community Services Inc, located in Green Valley, AZ, provides an extensive selection of substance use treatment options for both adults and children/adolescents dealing with simultaneous mental health issues. The center offers intensive outpatient programs and outpatient services, which include treatments utilizing methadone/buprenorphine or naltrexone. Emphasizing evidence-based methods such as cognitive behavioral therapy and the Matrix Model, this facility is dedicated to tackling concerns such as intimate partner violence, trauma, and co-occurring disorders. COPE Community Services Inc serves a diverse clientele, ensuring high-quality care and personalized treatment plans to facilitate recovery and promote overall well-being.

COPE Community Services Inc, located in Tucson, AZ, provides focused treatment for substance use and co-occurring mental health disorders for both adults and children. Their outpatient and intensive outpatient programs implement proven methods such as cognitive behavioral therapy and anger management techniques. This center is dedicated to offering customized services for individuals with a history of trauma and those facing concurrent mental health and substance use challenges. Catering to both male and female adults as well as young adults, COPE is recognized for its extensive range of treatment options and commitment to high-quality care. Clients have access to outpatient methadone/buprenorphine or naltrexone therapies, supporting a comprehensive recovery process.

Copes Outpatient, situated in La Grande, OR, provides a comprehensive array of rehabilitation services aimed at individuals in need of substance abuse treatment and transitional living options. The center features an intensive outpatient program, along with outpatient care that includes methadone/buprenorphine or naltrexone therapy, in addition to support for 12-step initiatives, anger management counseling, and brief intervention techniques. Copes Outpatient serves both men and women adults, as well as those affected by issues of intimate partner violence or domestic abuse. With tailored programs for adults and youth of all genders, this facility prioritizes individualized attention and aid for people throughout their recovery process.

COPE Community Services Inc, located in Tucson, AZ, provides holistic substance abuse treatment for both adults and children who also face mental health challenges. The center features intensive outpatient services, outpatient programs, and targeted therapies, including cognitive behavioral therapy and anger management strategies. Emphasizing support for clients with a history of trauma, the treatment is customized to accommodate personal requirements. There are dedicated programs designed for adolescents and young adults, as well as individuals experiencing dual diagnoses. Committed to delivering exceptional care, COPE Community Services Inc caters to male and female individuals in need of successful rehabilitation options.

Situated in Kansas City, MO, the COPS Outpatient Treatment Program delivers thorough substance use rehabilitation services for both adults and young adults. This center features a variety of programs, including intensive outpatient treatment, outpatient services, and standard outpatient therapies. Emphasizing high-quality care, the facility employs evidence-based methodologies such as brief intervention, cognitive behavioral therapy, and contingency management with motivational incentives. Tailored programs are offered for adult men, women, seniors, and older individuals. The center is inclusive, catering to both male and female clients to provide personalized recovery support for all individuals battling addiction.

CORE Medical Clinic Inc, located in West Sacramento, CA, provides extensive outpatient treatment for substance use for both adults and children/adolescents. The center features dedicated programs specifically for pregnant or postpartum women and clients involved with the criminal justice system. Emphasizing techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for relapse prevention, the clinic customizes its treatment approaches to meet the unique needs of each patient. Catering to both males and females, the services offered include outpatient treatment options with methadone, buprenorphine, or naltrexone, in addition to regular outpatient care. CORE Medical Clinic Inc is committed to delivering high-standard, evidence-supported treatment to facilitate individuals in their recovery journey.

At the Cornell Scott Hill Health Center in New Haven, CT, a full spectrum of recovery support is accessible. The center specializes in care for individuals grappling with addiction and mental health challenges, offering detox, substance abuse therapy, and specific interventions for co-occurring disorders in adults and children experiencing severe emotional difficulties. Their treatment modalities encompass inpatient hospital detox, continuous 24-hour hospital care, and flexible outpatient options to meet varied requirements. Specialized tracks are offered for adult men, adult women, and individuals with HIV or AIDS. Employing therapeutic techniques like 12-step program integration, anger resolution, and concise counseling strategies, the center ensures personalized recovery plans. The Cornell Scott Hill Health Center is committed to delivering exceptional, empathetic services to adults and young adults of all backgrounds seeking recovery.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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