NWVCIL Logo
Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6655 results

Daymark Recovery Services

Daymark Recovery Services, located in Lillington, NC, delivers a wide range of outpatient treatment options designed for both adults and children dealing with substance use issues and co-occurring mental health conditions. The center employs various techniques, including anger management, cognitive behavioral therapy, and brief interventions, to create personalized treatment plans. Daymark Recovery Services features dedicated programs for different groups, including teenagers, adult men, and women, addressing the unique needs of each demographic. Their outpatient services include methadone, buprenorphine, and naltrexone treatment options, reflecting a comprehensive approach to recovery. Focused on providing high-quality care, the center supports individuals of all genders throughout their healing journey.

Daymark Recovery Services

Daymark Recovery Services, located in Newland, NC, delivers focused treatment for individuals of all ages dealing with substance use disorders alongside mental health issues. The facility features both intensive outpatient and standard outpatient programs, which encompass treatments like methadone and buprenorphine. Utilizing methods such as 12-step programs and anger management, the center emphasizes personalized care for both men and women. By providing short-term interventions and customized strategies, Daymark Recovery Services is committed to offering effective and thorough support for individuals striving to overcome addiction and mental health difficulties.

Daymark Recovery Services

Daymark Recovery Services, located in Concord, NC, provides extensive treatment for adults experiencing substance use issues alongside mental health challenges, as well as for children facing significant emotional problems. Their outpatient offerings consist of intensive treatment options and specialized detoxification therapies using methadone and buprenorphine. Employing proven methodologies, such as cognitive behavioral therapy and anger management techniques, the center ensures that care is customized for each patient. With distinct programs aimed at adolescents and separate services for adult men and women, Daymark Recovery Services addresses a wide array of treatment needs. Their commitment to delivering gender-specific and age-sensitive care distinguishes them in their mission to promote sustained recovery for their clients.

Daymark Recovery Services
Winston Salem, NC

Daymark Recovery Services, located in Winston Salem, NC, provides targeted treatment for substance use and co-occurring disorders for both adults and children. The center offers intensive outpatient and outpatient options, including methadone and buprenorphine treatments. Employing evidence-based practices such as cognitive behavioral therapy and anger management, the facility has programs tailored specifically for adolescents, women, and those impacted by intimate partner violence. Committed to delivering high-quality care, this center serves individuals of all ages and genders who are in need of thorough rehabilitation services within a nurturing atmosphere.

Daymark Recovery Services
North Wilkesboro, NC

Daymark Recovery Services, located in North Wilkesboro, NC, provides targeted treatment solutions for substance use disorders and concurrent mental health challenges for both adults and youth. Their offerings encompass intensive outpatient programs, outpatient care, and treatments involving methadone, buprenorphine, or naltrexone. The center emphasizes techniques such as anger management, cognitive behavioral therapy, and the Matrix Model, addressing the needs of teenagers, survivors of sexual trauma, and those who have encountered various forms of distress. Catering to adults and seniors of all backgrounds, Daymark Recovery Services ensures a holistic and empathetic care experience, positioning itself as an excellent option for individuals in search of tailored rehabilitation support.

Daymark Recovery Services

Daymark Recovery Services, located in Lexington, NC, delivers thorough treatment for substance use disorders alongside specialized support for those experiencing serious mental health challenges. The facility offers a range of services including intensive outpatient programs and various outpatient care options, such as methadone, buprenorphine, or naltrexone treatments. Focusing on research-backed methods like cognitive behavioral therapy and anger management, Daymark Recovery Services serves both adults and youth, providing targeted programs for adult men, adult women, and adolescents. The center is committed to providing high-quality care that is personalized to meet the specific needs of each individual, promoting a comprehensive recovery journey for all clients.

Daymark Recovery Services

Daymark Recovery Services in Monroe, NC, provides thorough care for individuals struggling with addiction and those facing dual diagnoses of substance use and mental health challenges, including emotional difficulties in children. Through intensive and standard outpatient programs, this center delivers customized treatment strategies that feature anger management techniques, cognitive behavioral therapy, and brief intervention methods. Special provisions are made for teenagers, adult women, and survivors of sexual abuse, demonstrating a commitment to meeting the unique needs of various demographics. Daymark Recovery Services is recognized for its high-quality, individualized support, serving as a vital resource for individuals on their journey toward recovery and well-being.

Daymark Recovery Services

Nestled in Jefferson, NC, Daymark Recovery Services provides extensive outpatient care for individuals grappling with substance abuse and co-occurring mental health challenges, serving both young people and adults. The center features distinct programs designed for teenagers, adult women, and those who have gone through traumatic experiences, guaranteeing individualized support for everyone. By employing methodologies such as anger management, cognitive behavioral therapy, and brief intervention, Daymark Recovery Services extends high-quality treatment to its male and female clientele. The facility also offers outpatient treatment with methadone/buprenorphine or naltrexone, demonstrating its commitment to addressing a wide spectrum of needs and ensuring effective, personalized recovery for adults and children/adolescents.

Daymark Recovery Services

Nestled in Albemarle, NC, Daymark Recovery Services delivers a full spectrum of care for individuals grappling with substance abuse and co-occurring mental health challenges. Their offerings include intensive outpatient care, standard outpatient services, and tailored outpatient treatment using methadone, buprenorphine, or naltrexone. Employing proven therapeutic methods such as cognitive behavioral therapy and anger management, the facility serves both adults and young people, with specific programs designed for adolescents, adult men, and adult women. Daymark Recovery Services is recognized for its dedication to high-quality, individualized addiction recovery within a nurturing setting.

Daymark Recovery Services

Daymark Recovery Services in Asheville, NC, provides extensive care for adults and children facing addiction and mental health challenges. Their services include hospital-based inpatient detoxification and treatment, with specific modules for anger management, crisis intervention, and preventing relapse. They also offer specialized support for young people, as well as individuals who have experienced intimate partner violence, domestic abuse, or sexual assault. Daymark Recovery Services is committed to offering a secure and nurturing setting for all clients, ensuring personalized and high-quality treatment to foster sustained recovery and enhanced mental health.

Daymark Recovery Services

Daymark Recovery Services, situated in Statesville, NC, provides extensive addiction rehabilitation options. The facility offers inpatient detox, round-the-clock residential support, and shorter inpatient stays. Their therapeutic methods encompass 12-step guidance, brief interventions, and cognitive behavioral therapy. Prioritizing personalized attention, this center serves adults and young adults, regardless of gender. Daymark Recovery Services is distinguished by its customized treatment strategies and dedication to high-quality recovery, positioning it as a leading facility for individuals pursuing successful and individualized addiction healing.

Daymark Recovery Services

In High Point, NC, Daymark Recovery Services delivers tailored therapeutic interventions for individuals grappling with addiction and co-occurring mental health conditions, serving both youth and adults. The facility features robust intensive outpatient and outpatient options, incorporating medication-assisted treatment with methadone, buprenorphine, and naltrexone. Their therapeutic approach emphasizes brief intervention strategies, cognitive behavioral therapy, and the Matrix Model, specifically addressing the needs of those with trauma histories and dual diagnoses. Daymark Recovery Services welcomes clients of all ages and genders, providing individualized care pathways. Discover empathetic and impactful recovery support at this esteemed treatment facility.

Daymark Recovery Services

Daymark Recovery Services in Raeford, NC, delivers extensive outpatient care for substance use disorders, addressing the needs of adults and children dealing with co-occurring mental health challenges. The center features tailored services for adult males, adult females, and individuals with a history of sexual trauma. Their therapeutic interventions encompass anger management, brief intervention strategies, and cognitive behavioral therapy. Offering a range of services including outpatient, medication-assisted treatment (methadone/buprenorphine or naltrexone), and regular outpatient programs, Daymark Recovery Services is equipped to meet varied client requirements. Committed to providing high-quality support for both male and female individuals, Daymark Recovery Services focuses on guiding each person toward lasting recovery.

Daymark Recovery Services

Situated in Pinehurst, NC, Daymark Recovery Services delivers thorough addiction treatment for adults, encompassing individuals managing co-occurring mental health conditions. The facility features intensive outpatient services, general outpatient support, and specific medication-assisted treatments like methadone, buprenorphine, or naltrexone. Therapeutic modalities such as anger management, brief intervention, and cognitive behavioral therapy are adapted to each person's unique requirements. Daymark serves various groups through dedicated programs for adult men, women, and those with a history of trauma, reflecting its commitment to diverse populations. The center extends its quality care to both adults and younger individuals, with a particular emphasis on gender-affirming care.

Dayspring Health
Jellico, TN

Dayspring Health, located in Jellico, TN, delivers targeted outpatient treatment solutions for individuals grappling with substance abuse and accompanying mental health issues for both adults and children. The center offers an array of services, which include anger management sessions, cognitive behavioral therapy, and short-term interventions. Emphasizing support for pregnant and postpartum women, Dayspring Health provides customized care for this specific group. Catering to adults and seniors across all genders, the facility also offers outpatient treatments involving methadone, buprenorphine, or naltrexone. Renowned for its high standard of care and varied therapeutic methods, Dayspring Health is a reliable ally in the recovery process.

Dayton VA Medical Center

Dayton VA Medical Center, located in Dayton, OH, provides extensive services for those battling addiction, catering to both adults and young adults. This center features hospital inpatient detoxification and treatment specifically designed for substance use issues, including co-existing severe mental health disorders. It offers tailored programs designed for active duty service members, men, and women, addressing the needs of various groups. Employing strategies such as 12-step support, anger management, and brief interventions, the center emphasizes customized care for each patient. With a commitment to high-quality and personalized treatment, Dayton VA Medical Center aims to assist individuals as they embark on their recovery journey.

DeCoach Rehabilitation Centre

Situated in Xenia, OH, DeCoach Rehabilitation Centre provides a wide array of addiction recovery services specifically designed for both adults and young adults. The offerings encompass detoxification, treatment for substance use issues, transitional accommodation, and options for sober living. Individuals can select from various treatment modalities, including intensive outpatient, outpatient, and partial hospitalization, ensuring they receive the most appropriate level of care. Tailored programs are available for active duty military, as well as for adult men and women. The center employs methodologies such as 12-step facilitation, anger management techniques, and brief intervention strategies to customize care. DeCoach Rehabilitation Centre is committed to offering exceptional, gender-sensitive treatment that aids individuals on their path to recovery.

DeCoach Rehabilitation Centre

DeCoach Rehabilitation Centre, situated in Fairfield, OH, delivers a full spectrum of addiction recovery care for adults and adolescents. Their services encompass detox, comprehensive substance abuse therapy, and supportive living environments like halfway houses and sober living residences. They offer flexible treatment plans, including intensive outpatient, outpatient, and day programs. Employing methods such as 12-step guidance, anger management techniques, and brief interventions, the center personalizes recovery journeys. They also provide specialized support for active military members, adult men, and adult women. DeCoach Rehabilitation Centre is dedicated to providing high-quality, individualized treatment for all clients pursuing lasting sobriety.

Daystar Recovery Center
Detroit Lakes, MN

Situated in Detroit Lakes, MN, Daystar Recovery Center provides extensive substance use treatment designed specifically for adult men in a nurturing atmosphere. The facility offers a range of options, including long-term, short-term, and 24-hour residential programs, catering to adults, seniors, and younger adults. Focusing on 12-step facilitation, anger management, and brief interventions, the center delivers individualized care to suit varying needs. What distinguishes Daystar is its emphasis on adult men, allowing for focused attention and a specialized recovery journey. With a dedication to high-quality care and effective treatment strategies, this center serves as a vital resource for individuals in need of rehabilitation support.

De Novo Services
Salt Lake City, UT

De Novo Services, located in Salt Lake City, UT, provides a variety of outpatient rehabilitation options designed for adults and young adults facing challenges with substance use and concurrent mental health issues. Their range of specialized programs features detox, cognitive behavioral therapy, anger management, and 12-step support. The center offers outpatient detox services and treatment with medications such as methadone, buprenorphine, or naltrexone, serving both male and female clients. De Novo Services is particularly notable for its customized programs that address the unique needs of individuals dealing with both mental health conditions and substance use disorders. Emphasizing personalized treatment and evidence-based methods, this center is dedicated to delivering effective care for clients on their path to recovery.

Placeholder image
Decatur, GA

In Decatur, GA, DeKalb CSB provides extensive addiction recovery solutions for individuals and young adults. Services include medically supervised detox, partial hospitalization programs, and outpatient medication-assisted treatment. The center excels in addressing dual diagnoses, treating concurrent substance use and severe mental health conditions, with specialized care plans for active duty military, teenagers, and adult males. Employing strategies such as 12-step immersion, cognitive behavioral techniques, and motivational interviewing, DeKalb CSB delivers personalized, gender-informed treatment for all clients.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)