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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Decatur Morgan Hospital

Decatur Morgan Hospital, located in Decatur, AL, provides extensive detoxification services within its inpatient program and around-the-clock care. The center employs techniques such as motivational interviewing, brief interventions, and strategies aimed at preventing relapse to offer specialized care for adults, children, and adolescents, regardless of gender. With a strong emphasis on custom treatment plans, Decatur Morgan Hospital guarantees a personalized recovery experience. Individuals can anticipate exceptional care within a nurturing environment that fosters sustainable sobriety. For those in need of dedicated detox services in a hospital context, this facility stands out for its focus on individualized treatment, making it an essential option for individuals aiming to conquer addiction.

Decision Point Center Inc

Situated in Prescott, Arizona, Decision Point Center Inc. delivers complete substance abuse recovery services for adults and young adults. This establishment offers hospital-based inpatient detox, residential treatment, and intensive outpatient therapy. Emphasizing 12-step facilitation, anger management, and brief intervention strategies, Decision Point Center Inc. serves individuals with co-occurring substance use and significant mental health conditions. Specialized services are provided for active military personnel, adult men, and women. Their individualized methods and skilled support render it an excellent option for those pursuing impactful and custom-tailored recovery.

Decision Point LLC
Prescott, AZ

Decision Point LLC, located in Prescott, AZ, specializes in offering extensive treatment for adults and young adults dealing with co-occurring mental health conditions and substance use disorders. The center provides various treatment options, including intensive outpatient care, long-term residential stays, and standard outpatient services, effectively addressing a range of requirements. Through methods such as 12-step facilitation and anger management, as well as brief interventions, the staff at Decision Point LLC delivers customized support. They have specific programs designed for active-duty military personnel, adult men, and women, ensuring that treatment plans are personalized for every individual. With a commitment to high-quality care and evidence-based approaches, Decision Point LLC stands out as a reliable option for those in need of rehabilitation.

Defining Wellness Centers

Defining Wellness Centers, situated in Brandon, MS, delivers a full spectrum of addiction recovery care for adults and adolescents. This establishment features hospital-grade inpatient detox, comprehensive substance abuse treatment, and tailored therapies for those managing dual diagnoses of mental health conditions. Employing proven therapeutic methods like 12-step integration, cognitive behavioral techniques, and contingency management, Defining Wellness Centers prioritizes high-quality care for active military, adult men, and adult women. Their sex-segregated treatment tracks address the distinct requirements of each client, fostering a nurturing and successful path to recovery.

Denoon Recovery Center

Denoon Recovery Center, located in Waukesha, WI, provides an extensive selection of addiction recovery services. The facility features intensive outpatient care, day treatment options, and partial hospitalization programs. Emphasizing evidence-driven methodologies such as 12-step support, cognitive behavioral therapy, and brief intervention, this center addresses the needs of adults and young adults dealing with substance abuse issues and concurrent mental health challenges. Denoon Recovery Center also offers tailored programs for military personnel, as well as specific services for adult men and women. Dedicated to delivering high-quality care, this center fosters a nurturing atmosphere for those pursuing sustainable recovery.

DeNova
Lexington, KY

Situated in Lexington, KY, DeNova is a respected addiction treatment facility that specializes in intensive outpatient programs for individuals grappling with substance use disorders and related mental health conditions. The center offers medication-assisted treatment options, including methadone, buprenorphine, and naltrexone, serving both adults and young adults. DeNova utilizes proven therapeutic strategies such as 12-step facilitation, anger management techniques, and brief intervention to deliver holistic support. Recognizing diverse needs, the facility features distinct programs for active duty military personnel, adult men, and adult women, ensuring personalized care pathways. DeNova's dedication to high-quality services positions it as a leading option for those pursuing successful and individualized recovery.

Denton County MHMR Center

In Denton, TX, the Denton County MHMR Center delivers a complete spectrum of care for those pursuing recovery from addiction and co-occurring mental health challenges. This institution offers structured outpatient programs, including detoxification services and general outpatient support, employing proven methodologies like motivational interviewing, cognitive behavioral therapy, and the Matrix Model. Dedicated programs cater to active duty military, young people, and adult males. Emphasizing personalized treatment plans, the center supports adults and young individuals of every gender, fostering a nurturing setting for well-being and recuperation.

Denver Womens Recovery

Denver Women's Recovery, located in Denver, CO, is a dedicated rehabilitation facility designed specifically for adult women who are in need of treatment for substance use and related significant mental health challenges. The center provides various treatment options, such as intensive outpatient care and standard outpatient sessions, utilizing proven methods like cognitive behavioral therapy and contingency management. Tailored to meet the needs of adult women, seniors, and young adults affected by intimate partner violence, Denver Women's Recovery emphasizes personalized programs that ensure high-quality care and focused assistance. Additionally, active duty military members looking for recovery help are encouraged to seek services at this center.

Deer Hollow Recovery

Deer Hollow Recovery, situated in Draper, UT, specializes in delivering tailored substance use treatment for adults and young adults. The center offers various levels of care including intensive outpatient programs, outpatient services, and partial hospitalization options. Employing research-backed methods such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, it effectively serves clients who have experienced trauma and those dealing with dual diagnoses of mental health and substance use disorders. Deer Hollow Recovery welcomes clients of all genders, fostering an inclusive and holistic recovery environment. With an emphasis on high-quality care and individualized treatment strategies, this center is committed to aiding individuals in their recovery journey towards a sober life.

Deer Hollow Recovery

Deer Hollow Recovery, situated in Draper, UT, provides an extensive array of treatment options for substance use, including intensive outpatient, long-term residential, and outpatient services. The center emphasizes the use of 12-step programs, cognitive behavioral therapy, and motivational interviewing techniques, serving both adults and young adults from all backgrounds. With a special emphasis on individuals who have faced trauma and those struggling with both mental health and substance use issues, Deer Hollow Recovery focuses on personalized care within a nurturing atmosphere. Clients can look forward to evidence-based methodologies and high-quality support throughout their recovery process.

Deer Hollow Recovery

Deer Hollow Recovery, situated in Draper, UT, delivers extensive addiction treatment services for adults and young adults. They provide varied programs, including intensive outpatient, extended residential, and general outpatient plans, focusing on personalized care for individuals dealing with trauma and co-occurring mental health conditions. Employing proven methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, the center customizes treatment strategies. Deer Hollow Recovery accepts both male and female patients, fostering a welcoming and equitable atmosphere. Discover compassionate support and successful recovery strategies at this esteemed addiction treatment facility.

Delta Village Inc

Delta Village Inc, situated in Sanborn, NY, delivers exceptional care for men of all ages, from young adults to seniors, struggling with substance use disorders. The center offers extended stay residential programs and around-the-clock care, emphasizing 12-step integration, emotional regulation skills, and short-term problem-solving strategies. They have a particular expertise in supporting young adults, adapting their services to address the specific challenges faced by this group. Dedicated to providing both effective and empathetic recovery support, Delta Village Inc stands as a reliable option for those in need of thorough, individualized addiction treatment within a nurturing residential environment.

DeVaughn Intervention Teach and Trt

DeVaughn Intervention Teach and Trt in Baltimore, MD offers an extensive array of addiction recovery services tailored to individuals of all ages and genders. The center provides detoxification, treatment for substance use, and options for transitional housing. It particularly focuses on intensive outpatient treatment while incorporating 12-step facilitation, anger management techniques, and brief interventions. Specialized programs address the needs of adolescents, adult men, and women, delivering customized support for every person. With services available for adults, children and adolescents, as well as seniors, the facility emphasizes individualized care to encourage sustainable recovery. Whether clients are looking for male or female-specific programs, DeVaughn Intervention Teach and Trt is dedicated to offering top-quality care and assistance for all who seek help.

Denver Health Community Detox

Denver Health Community Detox in Denver, CO, delivers a complete suite of support for those on their journey to overcome substance use challenges. Their offerings include services for those living at home while detoxing, ongoing outpatient therapy, and temporary accommodations. Employing proven methods such as cognitive behavioral therapy and 12-step program guidance, the center supports adult men and women, including survivors of intimate partner or domestic violence. Specialized programs are available for young adults, offering targeted assistance. Denver Health Community Detox is dedicated to offering excellent, empathetic care designed for long-term sobriety.

Denton County MHMR Center

Situated in Flower Mound, Texas, the Denton County MHMR Center provides a wide range of rehabilitation services that address diverse requirements. This facility focuses on detoxification and treatment for substance use, as well as support for co-occurring disorders in adults and serious emotional disturbances in children. Emphasizing both intensive outpatient and outpatient programs, Denton County MHMR Center utilizes proven methods, including cognitive behavioral therapy and contingency management. It also features specialized programs aimed at active duty military members, adolescents, and adult males. Catering to both adults and younger individuals, the center offers personalized care for individuals of all genders. The Denton County MHMR Center is committed to offering high-quality support and services to those pursuing recovery.

Deerfield Centers for Addictions Trt

Deerfield Centers for Addictions Trt located in Warren, PA, delivers targeted substance use recovery programs designed specifically for both adults and older individuals. The center features intensive outpatient care, general outpatient services, and outpatient options for methadone, buprenorphine, or naltrexone therapy. Emphasizing anger management, short-term intervention, and cognitive behavioral strategies, this facility personalizes its services to meet the unique needs of each individual. Among its key offerings are programs dedicated to active duty military members, adolescents, and adult males. This center is committed to providing high-quality care for every client, regardless of their gender, who is in pursuit of effective addiction rehabilitation strategies.

Delaware Co Alcohol and Drug Service

Delaware Co Alcohol and Drug Service in Walton, NY, provides community-based support for individuals facing challenges with substance use. This center is equipped to assist adults experiencing co-occurring mental health conditions, as well as children with emotional difficulties. Their specialized services include guidance in following the 12-step model, strategies for managing anger, and short-term therapeutic approaches. Programs are specifically designed for members of the armed forces, young people, and adult men. Delaware Co Alcohol and Drug Service is committed to delivering effective care for adults and older adults across all gender identities. They offer a range of treatment options, including outpatient services, medication-assisted treatment with methadone, buprenorphine, or naltrexone, and ongoing outpatient support, all aimed at fostering lasting recovery.

Delphi Rise
Rochester, NY

Situated in Rochester, NY, Delphi Rise is a renowned rehabilitation facility focused on addressing substance use disorders. The center provides various treatment modalities, including outpatient services, methadone/buprenorphine, and naltrexone therapies, available for both adult men and women as well as young adults. What distinguishes Delphi Rise is its customized treatment programs, which encompass 12-step facilitation, anger management, and cognitive behavioral therapy. Of particular interest is their dedicated support for adult women, fostering a secure and encouraging space for those in recovery. Known for its high standards of care and a diverse array of evidence-based practices, Delphi Rise is an excellent option for individuals in search of personalized addiction recovery solutions.

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Delta Counseling Associates Inc located in Warren, AR, provides various outpatient treatment options for individuals struggling with substance use, catering to both adults and youth. The center has expertise in addressing co-occurring serious mental health disorders alongside substance use issues, delivering personalized counseling approaches. Focused on supporting active duty military members, adult males, and adolescents, this facility offers outpatient therapies including methadone, buprenorphine, or naltrexone treatments within a nurturing atmosphere. With a commitment to serving both men and women, the dedicated staff prioritizes top-quality care for individuals on their path to recovery from substance use and mental health difficulties.

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Greenwood, MS

Denton House CDC, situated in Greenwood, MS, provides extensive, top-tier recovery programs for adult men grappling with addiction and coinciding severe mental health conditions. This facility offers inpatient hospital detox and treatment, employing proven methods like 12-step facilitation and anger management. Denton House CDC also caters specifically to active military, adult men, and survivors of domestic violence. Prioritizing individualized support for male patients, the center fosters a nurturing atmosphere for healing. Denton House CDC delivers dedicated and expert treatment for seniors, young adults, and men pursuing successful recovery paths.

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Situated in Denver, CO, the Denver Health and Hospital Authority provides extensive care for individuals dealing with substance use issues alongside significant mental health challenges. Their offerings encompass intensive outpatient programs, outpatient care, and specific treatments using methadone/buprenorphine or naltrexone. By employing research-backed methods such as cognitive behavioral therapy and contingency management, this facility delivers customized support for adult men and women, including those who have faced intimate partner violence. With an emphasis on high-quality, personalized treatment, the center meets the needs of all clients in a nurturing atmosphere conducive to healing.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)