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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Desert Hope
Las Vegas, NV

Desert Hope, situated in Las Vegas, NV, is a premier treatment center dedicated to addressing substance use disorders and concurrent mental health challenges for individuals of all ages. The facility offers a range of programs, including intensive outpatient, outpatient services, and day treatment, all customized to meet the unique requirements of each client. Desert Hope employs specialized approaches such as anger management, cognitive behavioral therapy, and brief intervention strategies to provide thorough care for adults, particularly those with co-occurring conditions. Catering to adults and young adults across the gender spectrum, this center prioritizes delivering exceptional, individualized support to guide them toward lasting recovery.

Desert Hope Treatment Center

Desert Hope Treatment Center, situated in Las Vegas, NV, delivers complete care for those battling addiction and co-occurring mental health challenges. This center features inpatient hospital detox and treatment plans designed for adults and young adults. Desert Hope Treatment Center employs proven therapeutic methods like cognitive behavioral therapy, brief interventions, and anger management, offering distinct programs for adult men, adult women, and individuals with dual diagnoses. The facility is committed to delivering exceptional treatment, prioritizing the distinct requirements of each person to foster enduring sobriety.

Desert Mountain Healing IOP LLC

Desert Mountain Healing IOP LLC, located in Rio Rancho, NM, presents an extensive array of therapeutic services geared towards individuals pursuing recovery from addiction and similar mental health conditions. The facility features intensive outpatient treatment, outpatient services, and daytime treatment options, incorporating proven methods like 12-step programs, anger management, and brief interventions. It also offers tailored programs for military personnel, as well as for adult men and women, addressing the specific requirements of various groups. Serving both adults and young adults of all genders, Desert Mountain Healing IOP LLC is committed to providing exceptional care within a nurturing space to foster sustainable recovery and enhance overall health.

Desert Parkway Behav Healthcare Hosp

Desert Parkway Behav Healthcare Hosp, located in Las Vegas, NV, specializes in thorough rehabilitation services for detoxification, substance abuse, and dual diagnosis mental health disorders affecting both adults and minors. The facility provides around-the-clock inpatient care and utilizes a variety of therapeutic methods, including 12-step programs, anger management, and short-term interventions. There are tailored programs available for active military personnel, as well as separate services for adult men and women. Catering to individuals of all genders, Desert Parkway Behav Healthcare Hosp focuses on personalized treatment strategies to meet the distinct needs of each patient, making it an excellent option for those in need of effective addiction recovery solutions in Las Vegas.

Design for Change
Lancaster, CA

In Lancaster, California, "Design for Change" delivers a full spectrum of addiction treatment for adults and young adults. The center offers extended residential stays, detox services within a residential setting, and round-the-clock residential support. Emphasizing 12-step principles, anger control techniques, and short-term intervention strategies, "Design for Change" is equipped to help individuals dealing with co-occurring substance use disorders and significant mental health conditions. The facility also provides specialized care for active military members, as well as adult men and women, ensuring personalized recovery pathways for all.

Destination Hope
Fort Lauderdale, FL

Situated in Fort Lauderdale, FL, Destination Hope delivers a wide array of rehabilitation services tailored for adults and young adults facing challenges related to substance use disorders and concurrent mental health conditions. The facility offers residential detox services, around-the-clock residential treatment, and short-term residential options. Utilizing specialized methods like 12-step integration, anger management sessions, and brief interventions, Destination Hope addresses the specific requirements of each client. Their targeted programs are designed for adult men, adult women, and individuals who have dealt with trauma. This center is dedicated to providing high-quality care to both male and female clients, establishing itself as a premier choice for personalized addiction recovery.

Destination Hope
Fort Lauderdale, FL

Situated in Fort Lauderdale, FL, Destination Hope provides dedicated rehabilitation services for adults facing challenges with substance use disorders and concurrent severe mental health issues. The center offers a range of treatment options, including intensive outpatient programs, daytime outpatient services, and partial hospitalization, utilizing proven methods such as 12-step facilitation, anger management, and brief intervention strategies. Destination Hope serves both men and women, including individuals who have endured trauma, creating a safe and nurturing atmosphere for recovery. With customized programs that address various age groups and genders, this facility commits to personalized care and successful treatment for individuals striving to overcome addiction and mental health obstacles.

Detox Center of San Diego LLC

Detox Center of San Diego LLC, located in San Diego, California, provides thorough detox and substance use recovery programs for both adults and young adults. This center is dedicated to supporting those dealing with both substance use disorders and significant mental health challenges. With customized inpatient options and proven methods such as cognitive behavioral therapy and 12-step support, the facility guarantees top-notch care. It also offers specialized programs addressing the unique needs of both men and women. By emphasizing personalized treatment plans and gender-sensitive programs, the center highlights its dedication to comprehensive recovery for individuals battling addiction.

Department of Veteran Affairs Hospital

The VA Medical Center in Dallas, Texas, delivers extensive substance abuse recovery programs for adults and adolescents. This institution features hospital-based inpatient detox and care for various addictions, addressing co-occurring mental health issues as well. They offer distinct tracks for adult males, adult females, and survivors of domestic abuse, guaranteeing personalized support. Employing strategies such as 12-step peer support and emotional regulation techniques, the center emphasizes customized recovery journeys. Committed to high standards of treatment and a nurturing atmosphere, this center is devoted to guiding individuals toward lasting sobriety.

Department of Veterans Affairs Medical

Situated in Beckley, WV, the Department of Veterans Affairs Medical Center provides an extensive array of outpatient services aimed at treating substance use disorders alongside concurrent mental health challenges for both adults and children. The center is particularly dedicated to veterans, offering services that include detoxification, as well as outpatient treatments utilizing methadone, buprenorphine, or naltrexone. Additionally, the facility employs diverse therapeutic methods such as anger management, brief intervention, and cognitive behavioral therapy. Committed to delivering high-quality care, this center supports adult and young adult patients of all genders in their pursuit of personalized rehabilitation programs designed to meet their specific needs.

Desert Star Addiction Recovery Center

Situated in Tucson, AZ, Desert Star Addiction Recovery Center delivers extensive treatment for substance use disorders in adults, including those experiencing concurrent mental health issues. The center features various programs such as intensive outpatient treatment, outpatient day treatment, and partial hospitalization, employing evidence-based methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing. With tailored programs for adult men, women, and individuals with dual diagnoses, this center addresses a wide spectrum of client needs. Serving both adults and young adults of all genders, Desert Star Addiction Recovery Center is committed to offering personalized, high-quality care aimed at fostering sustainable recovery.

Destiny Recovery Center LLC

Destiny Recovery Center LLC, situated in Redlands, CA, provides extensive addiction recovery solutions for adults and adolescents. This establishment focuses on extended stay residential support, encompassing detoxification and addressing co-occurring substance use and severe mental health conditions. Employing methodologies like 12-step facilitation, anger management, and brief intervention, Destiny Recovery Center LLC delivers individualized programs for adult men and women, along with individuals with a history of trauma. Their round-the-clock residential care is available for both genders needing a nurturing setting for healing.

Desert Bloom Recovery LLC

Desert Bloom Recovery LLC, located in Victorville, CA, specializes in the treatment of substance use disorders through multiple modalities, including intensive outpatient programs, standard outpatient services, and day treatment options. The center employs evidence-based methodologies such as 12-step programs, anger management techniques, and brief intervention strategies. It also features distinct programs designed for active duty military members and those impacted by partner violence or trauma. Catering to adults and young adults of diverse backgrounds, this facility prioritizes personalized care and support. Desert Bloom Recovery LLC is committed to providing exceptional and thorough rehabilitation services to assist individuals in attaining long-term recovery from addiction.

Dept of Behavioral Healthcare Services

Situated in Portsmouth, VA, the Dept of Behavioral Healthcare Services provides targeted treatment for substance use issues, including dual diagnosis for adults and emotional challenges in children. The center features outpatient services along with methadone and buprenorphine therapies, offering anger management, cognitive behavioral therapy, and short-term interventions. Customized programs are designed for adolescents, adult males, and females, addressing the needs of adults, young adults, and children/adolescents. Specialized care for males and females ensures individualized treatment plans. Experience exceptional quality of care and research-backed methods at this center, where individuals can access extensive support throughout their recovery journey.

Detox Center II
Boca Raton, FL

Detox Center II, located in Boca Raton, FL, provides an all-encompassing approach to detoxification and treatment for substance use disorders in both adults and young adults dealing with significant mental health issues. The center features residential detox services, round-the-clock care, and short-term program options. By employing methods such as the 12-step model, anger management techniques, and brief intervention, it effectively serves men and women, including those in active military duty. With programs designed for various age groups and genders, Detox Center II offers personalized care to meet individual needs. The center's commitment to high-quality treatment and innovative service offerings positions it as a leading choice for individuals in need of reliable rehabilitation solutions.

Department of Human Services

The Department of Human Services located in Sparta, WI, provides targeted outpatient care for adults facing substance use challenges and those with significant mental health issues, as well as for children experiencing serious emotional difficulties. This center emphasizes personalized treatment plans, utilizing proven methods such as cognitive behavioral therapy, motivational interviewing, and counseling specific to substance use disorders. It serves both male and female adults, including young adults, ensuring that each individual's unique needs are met. The Department of Human Services offers a variety of outpatient options, including treatments with methadone, buprenorphine, or naltrexone, affirming its commitment to delivering top-notch care to assist individuals in their recovery process.

Destiny Sober Living

Destiny Sober Living in Phoenix, AZ, offers a complete program for adult men overcoming substance dependency. They provide extended, brief, and around-the-clock live-in care designed for those with significant co-occurring mental health challenges. Their expertise includes 12-step guidance, anger control techniques, and rapid intervention strategies. The center also supports individuals with histories of trauma, domestic abuse, or sexual assault. Catering to a wide age range from young adults to seniors, Destiny Sober Living is committed to delivering excellent support for lasting sobriety.

Destiny Sober Living

Destiny Sober Living in Laveen, AZ, delivers targeted care for adult women facing addiction and co-occurring mental health challenges. The center provides both extended and shorter residential stays, emphasizing principles of the 12-step program, techniques for managing anger, and swift therapeutic interventions. Specialized support is available for adult women who have experienced intimate partner violence, domestic abuse, or sexual trauma. Destiny Sober Living serves adults of all ages, including seniors and young adults, offering tailored, gender-exclusive treatment within a nurturing setting. Dedicated to high standards and personalized approaches, this institution stands as a guiding light for individuals aiming for profound healing and lasting sobriety.

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Desert Visions RTC, situated in Sacaton, AZ, is dedicated to offering extensive long-term residential treatment for those facing challenges with substance use disorders alongside significant mental health issues. The center is well-equipped to assist individuals grappling with the effects of intimate partner violence, sexual abuse, and domestic abuse. Prioritizing approaches such as 12-step facilitation, anger management, and targeted interventions, Desert Visions RTC serves a diverse population, including adults, children, teens, and young adults of all genders. Their superior residential services focus on tailored care and support, guiding clients towards successful recovery.

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Destiny Sober Living, situated in Buckeye, AZ, is a dedicated facility providing tailored substance use recovery services for adult men within a secure and nurturing setting. They offer flexible residential options, including extended stays, shorter durations, and round-the-clock support, all personalized to each individual's journey. Their approach integrates 12-step principles, anger management techniques, and brief intervention strategies to tackle dual diagnoses of substance abuse and significant mental health conditions. Additionally, they feature specialized programs designed for individuals who have experienced intimate partner violence, sexual assault, or other forms of trauma. Serving a broad demographic from young adults to seniors, Destiny Sober Living is committed to providing effective care that promotes sustained sobriety.

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Destiny Sober Living in Buckeye, AZ, provides thorough care for adult males struggling with substance abuse and co-occurring serious mental health conditions or emotional challenges. They offer various program lengths, including extended stays, shorter durations, and round-the-clock residential options. Treatment modalities include 12-step facilitation, anger management techniques, and brief intervention approaches. Unique programs are available for those affected by domestic violence, sexual assault, or trauma. Catering to a broad age range from young adults to seniors, the facility fosters a nurturing setting for healing. Emphasizing excellent treatment and personalized plans, Destiny Sober Living stands as a source of renewed hope for individuals pursuing effective recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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