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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Duffy Health Center Inc

Duffy Health Center Inc in Hyannis, MA is a dedicated facility providing specialized outpatient care for individuals of all ages struggling with substance use and co-occurring mental health conditions. Employing a variety of proven therapeutic methods like anger management, CBT, and brief interventions, the center crafts personalized treatment plans. Specific programs are available for teens, adult men, and women, ensuring each client receives focused support. Duffy Health Center Inc's expertise includes outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone for both male and female patients. This center distinguishes itself through its all-encompassing and individualized approach to treating adults and younger individuals.

Dunes East Hampton
East Hampton, NY

Dunes East Hampton, situated in East Hampton, NY, delivers a wide range of substance use recovery options, including intensive outpatient services, outpatient programs, and medication-assisted therapies such as methadone, buprenorphine, and naltrexone. The center emphasizes therapies like 12-step support, anger management, and cognitive behavioral approaches. Targeting adult men and women, as well as clients who have faced sexual trauma, this facility serves individuals across various age groups and genders. Dunes East Hampton fosters a nurturing atmosphere that prioritizes tailored and evidence-based treatment for those looking to conquer addiction.

Dunes East Hampton
Southampton, NY

Dunes East Hampton, situated in Southampton, New York, delivers extensive treatment for individuals struggling with substance use disorders, including adults and young adults facing concurrent serious mental health conditions or emotional challenges. This establishment features residential options for varying lengths of stay, including 24-hour care, employing scientifically validated methods such as 12-step integration, emotional regulation techniques, and cognitive behavioral interventions. Dunes East Hampton offers distinct tracks for adult men and women, alongside specialized support for survivors of intimate partner violence, addressing a wide spectrum of client requirements. Their gender-focused approach guarantees personalized treatment plans for both male and female patients. Discover exceptional care and customized assistance at Dunes East Hampton.

Dunmore Comprehensive Treatment Center

Situated in Scranton, PA, the Dunmore Comprehensive Treatment Center provides a variety of outpatient services for individuals battling substance use disorders. Their offerings encompass outpatient programs utilizing methadone, buprenorphine, or naltrexone. The center employs a multifaceted therapeutic strategy, integrating brief intervention techniques, cognitive behavioral therapy, and motivational interviewing to foster healing. Serving adult men and women, along with young adults, they offer tailored support adjusted for distinct gender and age demographics. Prioritizing high-quality care and personalized treatment journeys, the center is dedicated to assisting patients in achieving enduring sobriety.

Dynamic Youth Community Inc

Situated in Brooklyn, NY, Dynamic Youth Community Inc provides extended residential treatment for substance use issues specifically aimed at teenagers and young adults. The center emphasizes therapeutic techniques such as anger management, cognitive behavioral therapy, and motivational interviewing. Offering customized programs for both genders, this facility delivers exceptional care tailored to adults, children, and youth. Dynamic Youth Community Inc is distinguished by its commitment to young individuals, fostering a nurturing atmosphere for those on their path to recovery from substance use disorders. If you are in search of thorough addiction treatment within a residential environment, this center may be an ideal fit for your needs.

Dynamic Youth Community Inc

Situated in Brooklyn, NY, Dynamic Youth Community Inc delivers a variety of substance abuse therapies for both adults and teenagers. This center features intensive outpatient programs, standard outpatient services, and outpatient day treatment or partial hospitalization alternatives. It emphasizes techniques such as anger management, cognitive behavioral therapy, and motivational interviewing. The facility accommodates adult men and women as well as adolescents, providing tailored programs for each demographic. With a commitment to personalized care, Dynamic Youth Community Inc guarantees high-quality support for individuals of all genders and ages who are pursuing recovery from addiction.

EHS Inc
Buffalo, NY

EHS Inc, situated in Buffalo, NY, delivers targeted substance abuse recovery through its outpatient services. The facility offers diverse treatment modalities, encompassing outpatient methadone/buprenorphine or naltrexone support, standard outpatient care, and brief intervention strategies. Emphasizing cognitive behavioral therapy and motivational interviewing, EHS Inc customizes its offerings for adult men and women, including those with a history of trauma. Catering to adults and young adults of all genders, EHS Inc is dedicated to providing excellent care and assistance to those pursuing holistic addiction treatment in a supportive atmosphere.

EOH Acquisition Group LLC

EOH Acquisition Group LLC in East Orange, NJ, offers extensive addiction recovery programs for adults and adolescents. Their services include hospital-based inpatient detox and treatment for various substance use disorders, alongside support for co-occurring mental health challenges. They feature distinct tracks for adult men, adult women, and individuals managing dual diagnoses, personalizing each person's path to wellness. Employing methods like 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center fosters a complete recovery experience. EOH Acquisition Group LLC provides high-quality care for all genders, establishing itself as a reliable choice for individuals pursuing effective and empathetic addiction treatment.

EPEC Clinic LLC
Rosedale, MD

EPEC Clinic LLC, located in Rosedale, MD, provides outpatient treatment for substance use disorders and specializes in addressing the complexities of co-occurring substance use and severe mental health conditions in adults, as well as serious emotional challenges in children. The center offers outpatient services that include methadone/buprenorphine or naltrexone treatment in addition to regular therapy sessions. Through the use of telehealth options, EPEC Clinic LLC serves active duty military members, adolescents, and adult men, while also delivering programs tailored for adults and seniors across all genders. Committed to high-quality treatment and personalized care strategies, EPEC Clinic LLC strives to deliver thorough and meaningful rehabilitation solutions.

Duke City Recovery Toolbox LLC

Duke City Recovery Toolbox LLC in Albuquerque, NM, delivers outpatient programs for adults grappling with substance use disorders alongside significant mental health challenges. They offer focused support for those with serious emotional disturbances. Treatment modalities encompass outpatient medication management with methadone, buprenorphine, or naltrexone, alongside traditional outpatient services. The curriculum integrates 12-step principles, anger management techniques, and brief intervention strategies. Duke City Recovery Toolbox LLC features distinct offerings for adult men and women, as well as individuals who have faced intimate partner or domestic violence. Catering to adults and young adults of all genders, the facility is dedicated to high-quality, personalized care.

ETANO Center
Tucson, AZ

Situated in Tucson, AZ, ETANO Center delivers extensive outpatient care for individuals facing substance use challenges. Their expertise encompasses medically supervised withdrawal, medication-assisted treatment options like methadone, buprenorphine, or naltrexone, and targeted short-term therapeutic interventions. Employing approaches such as cognitive behavioral therapy and contingency management, the center supports adult men and women, including those managing concurrent pain and addiction. ETANO Center also extends its services to young adults, ensuring personalized support for every client's path to recovery through proven, individualized strategies.

EXCEL Treatment Center of Dover

EXCEL Treatment Center of Dover, located in Dover, NJ, provides focused treatment for adults and young adults facing challenges related to substance use, particularly those also experiencing serious mental health disorders or emotional difficulties. The facility offers a range of services including intensive outpatient programs, outpatient care, and partial hospitalization, utilizing methods such as 12-step facilitation, anger management, and brief interventions. Customized programs are designed for active duty military members as well as adult men and women. Emphasizing high-quality care, this center supports both male and female individuals seeking successful rehabilitation in a nurturing setting.

DuPage County Health Department

Situated in Addison, IL, the DuPage County Health Department provides outpatient treatment for substance use disorders tailored for adults and young adults. This center is adept at addressing co-existing substance use issues in conjunction with significant mental health conditions or emotional challenges. Services encompass outpatient treatment options involving methadone, buprenorphine, and naltrexone. The rehabilitation program employs research-backed methods including brief interventions, motivational interviewing, and strategies for preventing relapse. A distinctive aspect of this facility is its emphasis on supporting individuals who have dealt with trauma. It offers treatment for both male and female clients, promoting a thorough and high-quality recovery process.

Drug and Alcohol Treatment Services

Everett Recovery Center provides complete detox and addiction recovery services for adults and adolescents. This location offers hospital-based inpatient detoxification and treatment, with round-the-clock medical supervision. The center employs proven therapeutic methods, including cognitive behavioral therapy and motivational interviewing, delivering tailored support through customized recovery plans. Emphasizing a person-centered methodology, the program accommodates both male and female individuals. Clients can anticipate top-tier support within a nurturing setting designed to foster lasting sobriety. For those in search of impactful addiction therapy, explore the offerings at Everett Recovery Center.

ECHO Community Healthcare

ECHO Community Healthcare, situated in Evansville, IN, specializes in outpatient services for adults and children dealing with substance use issues and concurrent mental health disorders. This facility offers a variety of programs, including anger management, cognitive behavioral therapy, and brief intervention strategies. Emphasizing personalized care, ECHO Community Healthcare serves both adults and young adults, providing distinct programs tailored to males and females. The center includes outpatient treatments with methadone, buprenorphine, or naltrexone options, in addition to standard outpatient services. Patients can anticipate exceptional care and customized support throughout their recovery process.

Dynamic Youth Community Inc

Situated in Fallsburg, NY, Dynamic Youth Community Inc provides a full spectrum of substance abuse treatment solutions. This establishment excels in extended stay residential care, inpatient detoxification, and round-the-clock residential support for teens and young adults. Employing strategies such as anger control, cognitive behavioral therapy, and motivational interviewing, the center delivers personalized recovery plans for male and female patients. Their specialized programs are designed to address the distinct requirements of adolescents and young adults, guaranteeing excellent care and assistance during the healing process. Dynamic Youth Community Inc stands as a reliable choice for those in search of impactful addiction treatment and detox services.

EAC Network
Hempstead, NY

EAC Network in Hempstead, NY, provides tailored substance abuse recovery services for adolescents and adults. Their offerings include robust outpatient treatment options, general outpatient services, and medication-assisted treatment such as methadone, buprenorphine, or naltrexone. The center emphasizes evidence-based practices including 12-step program encouragement, anger control techniques, and swift intervention strategies. EAC Network serves adult males and females, with particular support for individuals affected by domestic or intimate partner abuse. They are committed to offering personalized care for all clients, fostering a secure setting conducive to healing and long-term sobriety.

EPIC Recovery Center
Saint Augustine, FL

Situated in Saint Augustine, FL, the EPIC Recovery Center delivers extensive outpatient services focused on detoxification, addressing substance use disorders, and managing co-occurring conditions for both adults and youth. This center emphasizes specialized support for individuals who have experienced trauma, offering customized programs for men and women. By employing evidence-based techniques such as cognitive behavioral therapy and the 12-step approach, EPIC Recovery Center is committed to providing high-quality care for those aiming to achieve recovery. Featuring options for outpatient detoxification and treatments involving methadone and buprenorphine, the center meets the distinct requirements of its clients within a nurturing setting. Programs are available for young adults and individuals of all genders who aspire to create positive transformations in their lives.

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Delray Beach, FL

Situated in Delray Beach, FL, the Drug Abuse Foundation of offers thorough detox services for those aiming to overcome substance addiction. This center provides both residential detoxification and round-the-clock residential programs, incorporating proven methods like brief intervention, cognitive behavioral therapy, and community reinforcement with vouchers. The facility is particularly focused on assisting pregnant and postpartum women while also serving adults, children, and adolescents of all gender identities. Committed to high-quality care and tailored treatment strategies, the Drug Abuse Foundation of creates a nurturing atmosphere for individuals ready to embark on their path to recovery.

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Delray Beach, FL

Situated in Delray Beach, Florida, the Drug Abuse Foundation offers an extensive array of treatment options for individuals facing substance use disorders alongside mental health challenges. This center specializes in intensive outpatient programs, as well as general outpatient services, and provides specific treatments involving methadone, buprenorphine, or naltrexone. Emphasizing 12-step support, anger management techniques, and short-term intervention strategies, the facility serves both adult men and women, including younger adults. There are also specialized programs designed for pregnant or postpartum women, ensuring customized care for every client. The center's dedication to high-quality, personalized treatment establishes it as a leading resource for effective rehabilitation solutions.

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Sandy, UT

EVNSQ LLC, situated in Sandy, UT, delivers focused care for substance misuse and dual diagnoses in adult men. Their comprehensive outpatient and intensive outpatient services integrate 12-step support, anger management techniques, and brief intervention strategies. This establishment offers customized assistance for adult men, individuals with a history of sexual abuse, and those dealing with trauma. Catering to adults, seniors, and young adults, EVNSQ LLC is committed to providing superior, personalized treatment to foster sustained recovery. Through their available outpatient day programs, this center aims to empower clients toward enduring well-being and freedom from addiction.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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