Medication-Assisted Treatment (MAT) Centers in Indiana
Medically reviewed by NWVCIL Editorial TeamLast reviewed: May 2026
Our directory lists 316 MAT programs across Indiana, with the largest concentrations in Indianapolis (41), Fort Wayne (16) and Evansville (11).
Medication-Assisted Treatment (MAT) combines FDA-approved medications — methadone, buprenorphine, and naltrexone — with counseling and behavioral therapies for comprehensive addiction care. MAT is the evidence-based gold standard for opioid and alcohol use disorders.
Treatment landscape in Indiana:
- Indiana recorded 2,244 drug overdose deaths in 2023 at 34.2 per 100,000 (CDC NCHS).
- 257 buprenorphine providers serve the state alongside only 15 methadone OTPs — buprenorphine carries most of the MAT load.
- Healthy Indiana Plan (HIP) covers all three FDA-approved MAT medications including long-acting injectables.
- The Family and Social Services Administration (FSSA) requires new OTPs to demonstrate unmet need before licensure under state cap rules.
MAT in Indiana — By the Numbers
34.2
per 100,000 drug overdose mortality (CDC 2023)
2,244
total overdose deaths in Indiana (2023)
406
verified facilities in our directory
315 / 406
facilities offering telehealth
365
accept Medicaid for treatment
15
SAMHSA-certified Opioid Treatment Programs
Top cities by buprenorphine provider density
Indianapolis (31) · Fort Wayne (11) · Anderson (9)
Sources: CDC NCHS Drug Overdose Mortality (2023) · SAMHSA Treatment Locator · NWVCIL directory snapshot, May 2026
Healthy Indiana Plan (HIP)
HIP covers all three FDA-approved MAT medications, including long-acting injectables; counseling is covered when delivered by a licensed addiction provider.
State regulations
Indiana caps the number of OTPs through the Family and Social Services Administration (FSSA); new OTPs must demonstrate unmet need before licensure.
- Cash or self-payment294
- Private health insurance282
- Medicaid281
- State-financed health insurance plan other than Medicaid224
- Medicare221
- Federal military insurance (e.g., TRICARE)204
- Outpatient268
- Regular outpatient treatment235
- Outpatient methadone/buprenorphine or naltrexone treatment233
- Intensive outpatient treatment109
- Residential/24-hour residential60
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MAT Treatment Providers in Indiana
MAT programs in Indiana
Indianapolis · 41 centers

CHOICE Program
Indianapolis, IN
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CleanSlate Centers
Indianapolis, IN
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Community Fairbanks Recovery Center
Indianapolis, IN
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Ethan Crossing Addiction Campus
Indianapolis, IN
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Evolve Indy LLC
Indianapolis, IN
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Journey Road Treatment Center
Indianapolis, IN
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Landmark Recovery
Indianapolis, IN
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Recovery Centers of America
Indianapolis, IN
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Salvation Army Harbor Light Center
Indianapolis, IN
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Shalom Healthcare Center
Indianapolis, IN
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CleanSlate Centers
Indianapolis, IN
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Adult and Child Health
Indianapolis, IN
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AppleGate Recovery
Indianapolis, IN
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Aspire Indiana Health
Indianapolis, IN
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Aspire Indiana Health
Indianapolis, IN
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Aware Recovery Care of Indiana LLC
Indianapolis, IN
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Hickory Treatment Center
Indianapolis, IN
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Sandra Eskenazi Mental Health
Indianapolis, IN
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Spero Health
Indianapolis, IN
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Community Health Network
Indianapolis, IN
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Miller Care Group
Indianapolis, IN
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Shalom Healthcare Center
Indianapolis, IN
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Spero Health
Indianapolis, IN
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Ascension St Vincent Indianapolis
Indianapolis, IN
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Avenues Recovery Center at
Indianapolis, IN
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Indianapolis Comprehensive
Indianapolis, IN
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Roudebush VA Medical Center
Indianapolis, IN
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Sandra Eskenazi MH Center
Indianapolis, IN
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Spark Recovery
Indianapolis, IN
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AppleGate Recovery
Indianapolis, IN
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New Vista North
Indianapolis, IN
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Adult and Child Center
Indianapolis, IN
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American Behavioral Counseling LLC
Indianapolis, IN
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American Behavioral Counseling LLC
Indianapolis, IN
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Bright Heart Health Indianapolis
Indianapolis, IN
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Community Behavioral Health
Indianapolis, IN
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Community Hospitals of Indiana Inc
Indianapolis, IN
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Cummins BH Systems Inc
Indianapolis, IN
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Fresh Start Treatment Facility
Indianapolis, IN
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Groups Recover Together
Indianapolis, IN
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Fort Wayne · 16 centers

AppleGate Recovery
Fort Wayne, IN
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Avenues Recovery Center at Fort Wayne
Fort Wayne, IN
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CleanSlate Centers
Fort Wayne, IN
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Fort Wayne Recovery
Fort Wayne, IN
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VA Northern Indiana Healthcare System
Fort Wayne, IN
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Otis R Bowen Ctr for Human Servs
Fort Wayne, IN
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Allendale Behavioral Health
Fort Wayne, IN
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BHG Fort Wayne Treatment Center
Fort Wayne, IN
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Legacy Treatment Center
Fort Wayne, IN
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Strive Recovery
Fort Wayne, IN
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Inspiration House
Fort Wayne, IN
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Parkview Behavioral Health
Fort Wayne, IN
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Bowen Health Clinic
Fort Wayne, IN
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Bowen Recovery Center
Fort Wayne, IN
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Groups Recover Together
Fort Wayne, IN
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Park Center Inc
Fort Wayne, IN
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Evansville · 11 centers

CleanSlate Centers
Evansville, IN
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Evansville Comprehensive Treatment Ctr
Evansville, IN
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Deaconess Cross Pointe
Evansville, IN
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ECHO Community Healthcare
Evansville, IN
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NOW Counseling Services LLC
Evansville, IN
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NOW Counseling Services LLC
Evansville, IN
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NOW Counseling Services LLC
Evansville, IN
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NOW Counseling Services LLC
Evansville, IN
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NOW Counseling Services LLC
Evansville, IN
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Southwestern Behavioral Healthcare Inc
Evansville, IN
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Anderson · 9 centers

Ascension Saint Vincent
Anderson, IN
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Bridges of Hope
Anderson, IN
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CleanSlate Centers
Anderson, IN
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Aspire Indiana Health
Anderson, IN
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Aspire Indiana Health
Anderson, IN
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Aspire Indiana Health
Anderson, IN
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Community Fairbanks Behavioral Health
Anderson, IN
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Aspire Indiana Health
Anderson, IN
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Groups Recover Together
Anderson, IN
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Bloomington · 9 centers

Boca Recovery Center
Bloomington, IN
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Indiana Center for Recovery
Bloomington, IN
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Groups Recover Together
Bloomington, IN
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CleanSlate Centers
Bloomington, IN
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Groups Recover Together
Bloomington, IN
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Indiana Ctr for Recovery/Alcohol and
Bloomington, IN
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Centerstone of Indiana Inc
Bloomington, IN
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Centerstone of Indiana Inc
Bloomington, IN
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Indiana University Health Bloomington
Bloomington, IN
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Kokomo · 9 centers

AppleGate Recovery
Kokomo, IN
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CleanSlate Centers
Kokomo, IN
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First City Recovery Center
Kokomo, IN
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Saint Vincent Kokomo
Kokomo, IN
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Turning Point System of Care
Kokomo, IN
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Community Howard Regional Health
Kokomo, IN
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Pinnacle Treatment Centers IN III LLC
Kokomo, IN
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Community Fairbanks Behavioral Health
Kokomo, IN
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Groups Recover Together
Kokomo, IN
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Jeffersonville · 8 centers

Clark Memorial Hospital
Jeffersonville, IN
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PAX Riverbend
Jeffersonville, IN
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Lifespring Health Systems
Jeffersonville, IN
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LifeSpring Health Systems
Jeffersonville, IN
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Spero Health
Jeffersonville, IN
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LifeSpring Health Systems
Jeffersonville, IN
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Family Ark
Jeffersonville, IN
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North Clark Medical Group
Jeffersonville, IN
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Lawrenceburg · 7 centers

East Indiana Comprehensive Trt Ctr
Lawrenceburg, IN
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Community Mental Health Center Inc
Lawrenceburg, IN
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Groups Recover Together
Lawrenceburg, IN
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Community Mental Health Center Inc
Lawrenceburg, IN
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FOCUS House
Lawrenceburg, IN
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INcompass Healthcare
Lawrenceburg, IN
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INcompass Healthcare
Lawrenceburg, IN
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Richmond · 6 centers

CleanSlate Centers
Richmond, IN
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Centerstone of Indiana Inc
Richmond, IN
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Richmond State Hospital
Richmond, IN
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Groups Recover Together
Richmond, IN
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Auburn · 5 centers

Allendale Treatment
Auburn, IN
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Community Health and Outreach Center
Auburn, IN
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Otis R Bowen Ctr for Human Servs
Auburn, IN
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Northeastern Center Inc
Auburn, IN
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Northeastern Center Inc
Auburn, IN
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Lafayette · 5 centers

Sycamore Springs LLC
Lafayette, IN
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CleanSlate Centers
Lafayette, IN
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Groups Recover Together
Lafayette, IN
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MedMark Treatment Centers
Lafayette, IN
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Indiana Community Addiction Network
Lafayette, IN
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Marion · 5 centers

VA Northern Indiana Healthcare System
Marion, IN
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Groups Recover Together
Marion, IN
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Radiant Health North
Marion, IN
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Radiant Health South
Marion, IN
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Muncie · 5 centers

CleanSlate Centers
Muncie, IN
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IU Health Ball
Muncie, IN
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Spero Health
Muncie, IN
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AppleGate Recovery
Muncie, IN
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Groups Recover Together
Muncie, IN
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New Albany · 5 centers

Groups Recover Together
New Albany, IN
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LifeSpring Health Systems
New Albany, IN
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Cleanse Clinic
New Albany, IN
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LifeSpring Health Systems
New Albany, IN
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New Albany Community Medical Services
New Albany, IN
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Seymour · 5 centers

New Beginnings Recovery Center LLC
Seymour, IN
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Seymour Comprehensive Treatment Center
Seymour, IN
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Centerstone of Indiana Inc
Seymour, IN
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Groups Recover Together
Seymour, IN
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ProTech Recovery
Seymour, IN
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Terre Haute · 5 centers

Anabranch Recovery Center
Terre Haute, IN
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Harsha Behavioral Center Inc
Terre Haute, IN
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Groups Recover Together
Terre Haute, IN
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Hamilton Center Inc
Terre Haute, IN
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Hickory Treatment Center
Terre Haute, IN
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Greenwood · 4 centers

Valle Vista Hospital
Greenwood, IN
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CleanSlate Centers
Greenwood, IN
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American Behavioral Counseling LLC
Greenwood, IN
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New Vista Outpatient Recovery Center
Greenwood, IN
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La Porte · 4 centers

NorthShore Health Centers
La Porte, IN
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LaPorte County Comp MH Council Inc
La Porte, IN
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Porter Starke Services Inc
La Porte, IN
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Groups Recover Together
La Porte, IN
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Lebanon · 4 centers

Aspire Indiana Health
Lebanon, IN
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Boone County Offices
Lebanon, IN
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Cummins BH Systems Inc
Lebanon, IN
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Integrative Wellness LLC
Lebanon, IN
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Martinsville · 4 centers

Recovery Works
Martinsville, IN
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Groups Recover Together
Martinsville, IN
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Centerstone of Indiana Inc
Martinsville, IN
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Merrillville · 4 centers

CleanSlate Centers
Merrillville, IN
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Addiction/Behavioral Csl Servs
Merrillville, IN
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Medmark Treatment Center
Merrillville, IN
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Regional Health Systems
Merrillville, IN
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Vincennes · 4 centers

Groups Recover Together
Vincennes, IN
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Samaritan Center Residency Clinic
Vincennes, IN
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Good Samaritan
Vincennes, IN
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Samaritan Center
Vincennes, IN
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Batesville · 3 centers

Community Mental Health Center Inc
Batesville, IN
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Community Mental Health Center Inc
Batesville, IN
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Community Mental Health Center Inc
Batesville, IN
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Bedford · 3 centers

Centerstone of Indiana Inc
Bedford, IN
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Groups Recover Together
Bedford, IN
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Serenity Now Psychiatric and Csl
Bedford, IN
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Carmel · 3 centers

Praxis of Carmel by Landmark Recovery
Carmel, IN
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Community Fairbanks
Carmel, IN
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Aspire Indiana Health
Carmel, IN
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Columbus · 3 centers

Columbus Regional Health
Columbus, IN
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Groups Recover Together
Columbus, IN
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Centerstone of Indiana Inc
Columbus, IN
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Connersville · 3 centers

Groups Recover Together
Connersville, IN
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Reid Outpatient Behavioral Health
Connersville, IN
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Centerstone of Indiana Inc
Connersville, IN
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Crawfordsville · 3 centers

Valley Oaks Health
Crawfordsville, IN
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Cummins BH Systems Inc
Crawfordsville, IN
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Groups Recover Together
Crawfordsville, IN
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Mishawaka · 3 centers

Praxis of South Bend
Mishawaka, IN
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Avenues Recovery Center at
Mishawaka, IN
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Indiana Ctr for Recovery Alcohol and
Mishawaka, IN
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Noblesville · 3 centers

Aspire Indiana Health
Noblesville, IN
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CleanSlate Centers
Noblesville, IN
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Indiana Community Addiction Network
Noblesville, IN
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Scottsburg · 3 centers

Centerstone of Indiana Inc
Scottsburg, IN
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Lifespring Health Systems
Scottsburg, IN
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Groups Recover Together
Scottsburg, IN
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Warsaw · 3 centers

CleanSlate Centers
Warsaw, IN
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Bowen Health
Warsaw, IN
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Otis R Bowen Ctr for Human Servs
Warsaw, IN
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Albion · 2 centers

NorthEastern Center Inc
Albion, IN
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Otis R Bowen Ctr for Human Servs
Albion, IN
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Angola · 2 centers

Otis R Bowen Ctr for Human Servs
Angola, IN
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Northeastern Center Inc
Angola, IN
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Avon · 2 centers

Indiana University West Hospital
Avon, IN
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Cummins BH Systems Inc
Avon, IN
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Bloomfield · 2 centers

SEE Purpose Treatment
Bloomfield, IN
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Charlestown · 2 centers

North Clark Medical Group
Charlestown, IN
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Chesterton · 2 centers

NorthShore Health Centers
Chesterton, IN
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Parkdale Center
Chesterton, IN
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Clarksville · 2 centers

Avenues Recovery Center at Louisville
Clarksville, IN
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Columbia City · 2 centers

Otis R Bowen Ctr for Human Servs
Columbia City, IN
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Park Center Inc
Columbia City, IN
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Corydon · 2 centers

Hickory Treatment Center at Corydon
Corydon, IN
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LifeSpring Health Systems
Corydon, IN
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Decatur · 2 centers

Adams Behavioral Health
Decatur, IN
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Park Center Inc
Decatur, IN
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Elkhart · 2 centers

CleanSlate Centers
Elkhart, IN
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Oaklawn Psychiatric Center Inc
Elkhart, IN
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Franklin · 2 centers

Tara Treatment Center Inc
Franklin, IN
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Groups Recover Together
Franklin, IN
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Gary · 2 centers

Semoran Treatment Center
Gary, IN
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Greencastle · 2 centers

CleanSlate Centers
Greencastle, IN
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Cummins BH Systems Inc
Greencastle, IN
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Greenfield · 2 centers

Groups Recover Together
Greenfield, IN
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Community Fairbanks Behavioral Health
Greenfield, IN
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Greensburg · 2 centers

Groups Recover Together
Greensburg, IN
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Centerstone of Indiana Inc
Greensburg, IN
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Jasper · 2 centers

Groups Recover Together
Jasper, IN
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LifeSpring Health Systems
Jasper, IN
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LaGrange · 2 centers

Otis R Bowen Ctr for Human Servs
LaGrange, IN
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Northeastern Center Inc
LaGrange, IN
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Lexington · 2 centers

Centerstone of Indiana Inc
Lexington, IN
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Centerstone of Indiana Inc
Lexington, IN
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Madison · 2 centers

Centerstone of Indiana Inc
Madison, IN
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LifeSpring Health Systems
Madison, IN
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Peru · 2 centers

4C Health
Peru, IN
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Grove Estate Addiction Treatment
Peru, IN
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Plymouth · 2 centers

Otis R Bowen Ctr for Human Servs
Plymouth, IN
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Michiana Behavioral Health
Plymouth, IN
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Rockport · 2 centers

NOW Counseling Services LLC
Rockport, IN
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LifeSpring Health Systems
Rockport, IN
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Salem · 2 centers

Groups Recover Together
Salem, IN
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Lifespring Health Systems
Salem, IN
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Shelbyville · 2 centers

Community Fairbanks Behavioral Health
Shelbyville, IN
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Groups Recover Together
Shelbyville, IN
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South Bend · 2 centers

Oaklawn Psychiatric Center Inc
South Bend, IN
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Cardinal Recovery
South Bend, IN
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Valparaiso · 2 centers

Porter Starke Services Inc
Valparaiso, IN
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Porter Starke Services Inc
Valparaiso, IN
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Wabash · 2 centers

Otis R Bowen Ctr for Human Servs
Wabash, IN
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Groups Recover Together
Wabash, IN
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Washington · 2 centers

Knox County Hospital
Washington, IN
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Groups Recover Together
Washington, IN
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Alexandria · 1 center

CleanSlate Centers
Alexandria, IN
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Attica · 1 center

Valley Oaks Health
Attica, IN
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Aurora · 1 center

St Elizabeth Physicians
Aurora, IN
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Austin · 1 center

LifeSpring Health Systems
Austin, IN
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Bluffton · 1 center

Park Center Inc
Bluffton, IN
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Brookville · 1 center

Community Mental Health Center Inc
Brookville, IN
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Delphi · 1 center

Valley Oaks Health
Delphi, IN
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Dyer · 1 center

Franciscan Alliance Inc
Dyer, IN
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East Chicago · 1 center

Regional Health Systems
East Chicago, IN
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Elwood · 1 center

Aspire Indiana Health
Elwood, IN
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English · 1 center

LifeSpring Health Systems
English, IN
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Goshen · 1 center

Oaklawn Psychiatric Center Inc
Goshen, IN
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Hartford City · 1 center

Grant Blackford Mental Health Inc
Hartford City, IN
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Hobart · 1 center

Groups Recover Together
Hobart, IN
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Huntington · 1 center

Otis R Bowen Ctr for Human Servs
Huntington, IN
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Kendallville · 1 center

Northeastern Center Inc
Kendallville, IN
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Knox · 1 center

Porter Starke Services Inc
Knox, IN
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Ladoga · 1 center

Ladoga Recovery Center LLC
Ladoga, IN
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Linton · 1 center

Hickory House Recovery
Linton, IN
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Loogootee · 1 center

Knox County Hospital
Loogootee, IN
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Lowell · 1 center

Heartland Wellness Center
Lowell, IN
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Morocco · 1 center

IFC Clinics
Morocco, IN
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New Castle · 1 center

Groups Recover Together
New Castle, IN
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Newburgh · 1 center

Brentwood Springs
Newburgh, IN
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North Vernon · 1 center

Groups Recover Together
North Vernon, IN
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Osgood · 1 center
Paoli · 1 center

LifeSpring Health Systems
Paoli, IN
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Portage · 1 center

Porter Starke Services Inc
Portage, IN
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Rochester · 1 center

4C Health
Rochester, IN
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Rockville · 1 center

Hickory Treatment Center at Rockville
Rockville, IN
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Rushville · 1 center

Centerstone of Indiana Inc
Rushville, IN
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Spencer · 1 center

Centerstone of Indiana Inc
Spencer, IN
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Tell City · 1 center

LifeSpring Health Systems
Tell City, IN
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Tipton · 1 center

Community Fairbanks Behavioral Health
Tipton, IN
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Vevay · 1 center

Community Mental Health Center Inc
Vevay, IN
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West Harrison · 1 center

Community Mental Health Center Inc
West Harrison, IN
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Winchester · 1 center

Groups Recover Together
Winchester, IN
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Showing 300 of 316 MAT programs in Indiana. Browse all centers in Indiana
Frequently Asked Questions About MAT in Indiana
Can I start mat while I am on probation or parole in Indiana?
Yes. Federal guidance and Indiana law protect your right to continue FDA-approved MAT while under community supervision. Share your probation-officer contact with the clinic so they can document treatment — probation cannot legally require you to stop mat.
Can I get free mat treatment in Indiana?
Free mat treatment is possible in Indiana for patients who qualify for Healthy Indiana Plan (HIP), are enrolled in State Opioid Response–funded clinics, or use charity-care programs at community behavioral-health centers. Call 988 or 1-800-662-4357 for live referrals.
Does Healthy Indiana Plan (HIP) cover long-acting buprenorphine (Sublocade) or naltrexone (Vivitrol)?
Yes. Healthy Indiana Plan (HIP) covers Sublocade and Vivitrol as part of the MAT benefit; most plans require prior authorization documenting prior MAT adherence. Billing is handled by the Indiana provider as a medical (not pharmacy) benefit.
Does COBRA cover mat in Indiana?
Yes. COBRA continues your former employer’s health plan unchanged for up to 18 months, including MAT benefits. The monthly COBRA premium is higher than a marketplace plan for most people; explore Marketplace options too before the 60-day COBRA deadline.
Was the DEA X-waiver requirement for buprenorphine removed in Indiana?
Yes — federal Congress eliminated the X-waiver in December 2022, so any Indiana clinician with a DEA registration can now prescribe buprenorphine for OUD. Continuing-education requirements apply; training is free through Providers Clinical Support System (PCSS) and SAMHSA.
Does length of treatment with mat affect outcomes?
Yes. Meta-analyses consistently find that patients who remain on MAT longer than 12 months have lower rates of relapse, infectious disease, and overdose death. Indiana Medicaid-funded programs report improved retention with long-acting injectables compared to sublingual treatment.
Can I start mat while I’m still using opioids?
For methadone and buprenorphine, continued opioid use at entry is expected — the medication is designed to stop use safely. For naltrexone, 7–14 opioid-free days are required first. Your Indiana clinician will confirm the correct induction strategy at intake.
Will I feel high or sedated after the first mat dose?
Most patients feel calm relief of withdrawal rather than euphoria. Mild drowsiness is common the first day; avoid driving or operating machinery until you know how you react. Severe sedation is rare and warrants a call to the Indiana clinic.
Can mat affect my heart?
Methadone can prolong the QTc interval on ECG; Indiana clinics screen patients with baseline and follow-up ECGs. Buprenorphine and naltrexone do not carry this risk. Patients with cardiac disease can safely use MAT under close cardiology and MAT-team coordination.
Will pediatricians in Indiana know how to care for my MAT-exposed baby?
Yes. Indiana pediatricians and neonatologists receive training on caring for infants with prenatal opioid exposure. Eat, Sleep, Console protocols, parental involvement, and compassionate postpartum care are standard. Share your MAT history openly so the team can tailor monitoring.
Will my counseling sessions be confidential?
Yes — counseling records are protected by 42 CFR Part 2 and HIPAA. The counselor cannot disclose your MAT status or session content to family, employer, or law enforcement without your specific written consent or a narrowly tailored court order.
Can I travel internationally with mat from Indiana?
Yes, with proper documentation. Bring a letter from your Indiana MAT prescriber, medication in its original pharmacy container, and check destination-country rules — some countries restrict methadone and buprenorphine. The International Narcotics Control Board maintains destination-country guidance.
Other Treatment Options in Indiana
Medication-Assisted Treatment in Other States
Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)







