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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Greater Boston Addiction Center

Situated in Needham Heights, MA, the Greater Boston Addiction Center specializes in treatment for substance use disorders among adults and young adults. The center offers a range of services, including intensive outpatient programs, outpatient day therapy, and partial hospitalization. Emphasizing methodologies such as 12-step support, anger management, and brief intervention techniques, it serves clients dealing with both substance use and serious mental health challenges. Additionally, there are tailored programs for active military members, as well as for men and women. This facility is committed to delivering high-quality care and customized treatment strategies, guiding individuals toward successful recovery.

Greater Family Health

Greater Family Health, situated in Elgin, IL, stands as a leading facility for outpatient care, addressing substance use disorders and co-occurring mental health challenges in adults, as well as emotional difficulties in children. This center offers comprehensive care, encompassing medication-assisted treatment (methadone/buprenorphine or naltrexone), brief interventions, cognitive behavioral therapy, and motivational interviewing. Tailored programs are available for adolescents, adult men, and women, ensuring that adults and young adults of all gender identities receive high-quality, research-backed treatment. For those in pursuit of personalized and successful rehabilitation, Greater Family Health is committed to guiding individuals on their path to wellness.

Greater Family Health

Greater Family Health, situated in Wheeling, IL, is a respected institution providing outpatient services for individuals battling substance use challenges. Their expertise lies in addressing dual diagnoses, where substance abuse intertwines with significant mental health conditions in adults or emotional difficulties in young people. The center offers various treatment modalities, including medication-assisted treatment (methadone/buprenorphine/naltrexone), general outpatient care, and distinct programs designed for teenagers, adult men, and adult women. Employing scientifically validated methods like brief intervention, cognitive behavioral therapy, and motivational interviewing, Greater Family Health delivers effective and personalized recovery support to all clients.

Greater Seacoast Community Health

Greater Seacoast Community Health, situated in Portsmouth, NH, delivers outpatient care centered on detox and addiction recovery. Their services include outpatient detoxification, medication-assisted treatment (methadone, buprenorphine, naltrexone), and evidence-based therapies like brief intervention, CBT, and motivational interviewing. This center prioritizes personalized treatment plans for adults and young adults, regardless of gender. Greater Seacoast Community Health is recognized for its customized approaches and dedication to high-quality support for individuals pursuing sobriety.

Green Bay Comprehensive Treatment Ctr

Green Bay Comprehensive Treatment Ctr in Green Bay, WI, provides comprehensive outpatient care for addiction and substance abuse recovery. Their treatment methods include cognitive behavioral therapy, anger management, and brief intervention, serving adults and young adults of all genders. The center offers specialized support for individuals facing co-occurring mental health and addiction issues, pregnant or new mothers, and those navigating the legal system. Emphasizing personalized care, they deliver outpatient detox and medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone.

Green Country Behavioral Hlth Servs

Green Country Behavioral Hlth Servs located in Muskogee, OK, provides a wide array of outpatient services targeted towards detoxification, substance abuse treatment, and addressing co-occurring mental health challenges in adults, as well as emotional issues in children. The center excels in outpatient detox and offers treatment options involving methadone and buprenorphine. It employs various therapeutic techniques, including anger management and cognitive behavioral therapy, to support clients of all genders, including adults and seniors. The facility also features specialized programs for individuals with dual diagnoses and for pregnant or postpartum women, emphasizing personalized care. With a commitment to high-quality treatment and individualized attention, Green Country Behavioral Hlth Servs fosters a nurturing and efficient atmosphere for individuals on their path to recovery.

Green Hill Recovery LLC

Green Hill Recovery LLC, located in Raleigh, NC, delivers a complete spectrum of addiction treatment and tailored support for those facing concurrent mental health challenges. Their offerings include intensive outpatient care, day treatment, and partial hospitalization programs, all grounded in proven therapeutic modalities like 12-step facilitation, cognitive behavioral therapy, and contingency management. The center prioritizes individuals with dual diagnoses and young adults, serving adult, senior, and young adult male patients. Green Hill Recovery LLC is committed to delivering exceptional, personalized services to guide clients toward sustained recovery and enhanced mental wellness.

Greater Family Health

Greater Family Health, situated in Sycamore, IL, provides targeted outpatient services for individuals of all ages facing substance use and related mental health challenges. The facility employs proven therapeutic methods, including cognitive behavioral therapy and motivational interviewing. Catering to various needs, Greater Family Health offers distinct programs for teenagers, adult males, and adult females. Adults and adolescents can find suitable options for methadone/buprenorphine treatment or general outpatient support, with gender-specific care available. This center is committed to a caring and successful strategy for guiding people toward lasting recovery.

Greater Nashua Council on Alcoholism

The Greater Nashua Council on Alcoholism, situated in Nashua, NH, delivers extensive programs for individuals of all ages battling substance use challenges. Their offerings include in-depth residential stays, structured outpatient services, and flexible regular outpatient care, all customized to each person's unique recovery journey. The center is particularly adept at addressing dual diagnoses, supporting adults with co-occurring substance use and significant mental health conditions, and assisting children experiencing profound emotional difficulties. Utilizing proven methods such as 12-step program support, anger management techniques, and brief intervention strategies, they provide high-caliber support for men and women on the path to lasting sobriety.

Greater Family Health
Hanover Park, IL

Situated in Hanover Park, IL, Greater Family Health delivers extensive outpatient rehabilitation services. This center focuses on addressing substance use disorders in adults facing simultaneous mental health challenges and emotional issues in children. The therapeutic techniques employed include cognitive-behavioral therapy, motivational interviewing, and brief intervention strategies. Customized programs are designed for adolescents as well as adult men and women, emphasizing personalized care. The facility offers outpatient treatment options with methadone/buprenorphine or naltrexone, in addition to standard outpatient services. Greater Family Health is dedicated to providing high-quality care and using evidence-based methods to support recovery for adults and young adults of all genders.

Greenbriar Treatment Center

Situated in Washington, PA, Greenbriar Treatment Center delivers long-term residential treatment for adult males dealing with substance use issues. The center emphasizes 12-step programs, anger management, and cognitive behavioral therapy, fostering a nurturing atmosphere for individuals on their path to recovery. With options for transitional housing and specialized programs designed specifically for men, Greenbriar Treatment Center addresses the unique requirements of its patient population. Catering to adults, seniors, and young adults, this facility is committed to providing high-quality care and efficient rehabilitation services in a male-focused environment. If you or someone you care about is seeking a structured and supportive approach to recovery, Greenbriar Treatment Center is ready to assist.

Greenbriar Treatment Center

Greenbriar Treatment Center located in Washington, PA, delivers thorough detoxification and substance use treatment options. The center offers a range of treatment modalities, including inpatient detox, 24-hour residential support, and short-term residential care. By incorporating methods such as 12-step programs, anger management techniques, and cognitive behavioral therapy, this center addresses the needs of adult men and women facing co-occurring mental health issues alongside substance use disorders. Greenbriar Treatment Center is committed to serving both adults and young adults of all genders, providing tailored support for each person. With an emphasis on high-quality, evidence-based approaches, this facility is focused on aiding individuals on their recovery journey.

Greater Essex Counseling Services

Greater Essex Counseling Services, located in Newark, NJ, provides targeted treatment for substance use disorders, particularly for adults facing serious mental health challenges as well as for children with emotional issues. This center emphasizes intensive outpatient programs and offers outpatient treatments with methadone, buprenorphine, and naltrexone. They provide services such as 12-step facilitation, anger management, and brief interventions. The facility designs customized programs for adult men, women, and those affected by intimate partner or domestic violence. Catering to both adults and young adults of diverse backgrounds, this center is committed to delivering exceptional care through various therapeutic methods aimed at fostering recovery and enhancing overall well-being.

Greenbriar Treatment Center
New Kensington, PA

Situated in New Kensington, PA, Greenbriar Treatment Center specializes in providing targeted substance abuse treatment for both adults and young adults through a range of programs including intensive outpatient, outpatient, and day treatment options. The center employs evidence-based methods such as 12-step support, anger management techniques, and cognitive behavioral therapy to customize care for male and female clients alike. By prioritizing individualized treatment plans, Greenbriar Treatment Center fosters a nurturing and thorough environment for individuals pursuing recovery from addiction. Dedicated to offering exceptional care, this center is recognized for its unique programs tailored to the needs of adult men and women, serving as an essential support system for those striving for sobriety.

Greenbriar Treatment Center

Greenbriar Treatment Center located in Wexford, PA, provides a wide range of substance use rehabilitation options, including intensive outpatient treatment, outpatient services, and partial hospitalization programs. Focused on methods such as 12-step guidance, anger management, and cognitive behavioral therapy, the center offers customized support for adult men and women. Catering to adults and young adults of all genders, Greenbriar Treatment Center prioritizes individualized treatment plans to meet specific needs effectively. The center's dedication to high-quality care and specialized programs for various groups positions it as a reliable option for those pursuing compassionate and evidence-informed addiction treatment in the Wexford region.

Greater Philadelphia Asian Social Serv

Located in Philadelphia, PA, Greater Philadelphia Asian Social Serv provides a full spectrum of addiction recovery options delivered via outpatient services, featuring methadone/buprenorphine or naltrexone therapies. This center focuses on providing specialized care for adults and young adults, with distinct programs designed for male and female individuals. Their approach emphasizes 12-step facilitation, anger management techniques, and brief intervention strategies, aiming to support those on their journey to recovery. A unique offering is their dedicated program for individuals involved with the criminal justice system, demonstrating a commitment to addressing complex needs. Greater Philadelphia Asian Social Serv is recognized for its high standards of care and personalized treatment strategies.

Green River Medical Center

Situated in Green River, UT, Green River Medical Center delivers an extensive array of outpatient rehabilitation services for both adults and elderly individuals. The center specializes in detoxification, treatment for substance abuse, and addressing co-occurring mental health disorders. It offers outpatient detox programs alongside options for methadone, buprenorphine, or naltrexone therapy. Emphasizing techniques such as anger management, cognitive behavioral therapy, and brief intervention, the facility accommodates both male and female clients, including survivors of intimate partner violence. Its program is designed to meet the specific requirements of individuals dealing with significant mental health challenges or emotional issues. Green River Medical Center is committed to offering high-quality support for those pursuing recovery from addiction.

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Situated in Nashua, NH, Greater Nashua Mental Health provides a thorough array of recovery programs for individuals of all ages. This institution focuses on detox, addiction treatment, and care for dual diagnoses. Their offerings are designed for patients facing significant mental health challenges and emotional distress. They offer intensive outpatient services, outpatient detox, and diverse therapeutic methods including 12-step support, cognitive behavioral therapy, and short-term counseling. There are also distinct programs for teens, adult men, and survivors of trauma. Greater Nashua Mental Health delivers personalized support to both male and female patients, ensuring excellent care for those requiring assistance.

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Greater Seacoast Community Health, situated in Somersworth, NH, specializes in outpatient services for individuals struggling with substance use disorders. They offer tailored treatment plans, incorporating techniques like cognitive behavioral therapy and motivational interviewing, for adults and young adults. The center is dedicated to providing personalized support for both men and women navigating addiction. Their programs include outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, all delivered within a nurturing setting. For those seeking effective and individualized addiction care, this center is prepared to guide you toward sustained recovery.

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Green Lake, WI

Green Lake County, situated in Green Lake, WI, delivers outpatient services for adults grappling with substance use disorders, particularly those with co-occurring severe mental health conditions or children experiencing emotional disturbances. This facility employs standard outpatient treatment methodologies, incorporating strategies like 12-step facilitation, anger management techniques, and brief intervention. Recognizing diverse needs, Green Lake County offers specialized programming for adolescents, adult women, and individuals impacted by intimate partner violence. Catering to a broad demographic including adults and seniors of all genders, the center is committed to providing individualized care. Clients can expect to find empathetic and results-oriented support aimed at fostering comprehensive well-being and sustained recovery.

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Situated in Pittsburgh, PA, Greenbriar Treatment Center delivers extensive treatment options for individuals grappling with substance use issues, including both adults and young adults. The facility offers various programs such as intensive outpatient care, outpatient services, and day treatment options like partial hospitalization. Emphasizing methods like 12-step support, anger management, and cognitive behavioral therapy, Greenbriar customizes its strategies to meet the unique needs of each client. The center also provides dedicated programs for adult men and women, ensuring tailored support. Committed to excellence, this facility offers a range of services for both genders, fostering a nurturing environment for those on their path to recovery from substance use disorders.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)