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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Hope and Healing

"Hope and Healing" in Mesa, AZ, provides extensive recovery support for adults and young adults confronting addiction and co-occurring severe mental health conditions. Their offerings include intensive outpatient, day treatment, and partial hospitalization programs, all grounded in proven therapies like 12-step facilitation, anger management, and cognitive behavioral therapy. This facility excels in delivering personalized care for both men and women, recognizing the unique needs of each client. "Hope and Healing" is distinguished by its dedication to superior treatment and customized plans, aiding individuals in their path to sustained recovery.

Hope Health Family Practice

Hope Health Family Practice, located in Rowland, NC, delivers extensive care for individuals of all ages struggling with addiction and co-occurring severe mental health conditions. The center features both extended stay and round-the-clock residential services, customized for each person's specific requirements. Employing strategies such as cognitive behavioral therapy, addiction counseling, and remote therapy options, the facility promotes a complete recovery journey. Dedicated to tailored support, this center serves adults and older adults, accommodating all genders. Their distinct commitment to creating unique treatment pathways signifies a dedication to providing excellent support and care for those on their healing journey.

Hope House
Scottsdale, AZ

Situated in Scottsdale, Arizona, Hope House delivers targeted rehabilitation services for those facing challenges with substance abuse and concurrent serious mental health issues. The facility offers various levels of care, including inpatient programs, residential treatment, and round-the-clock support for both adults and young adults. Emphasizing cognitive behavioral therapy, anger management, and short-term interventions, the center customizes its approach to meet the distinct needs of each client. Specialized programs are available for adult men and women, along with services for individuals affected by intimate partner violence. Hope House is committed to providing exceptional care for all patients seeking recovery and support in overcoming addiction and mental health difficulties.

Hope Rising
Hurricane, UT

Situated in Hurricane, UT, Hope Rising specializes in providing tailored substance use treatment for both adults and young adults within a nurturing atmosphere. Emphasizing long-term, residential, and short-term residential options, the center also offers brief interventions and counseling specific to substance use disorders. A distinguishing feature of this center is its commitment to personalized care, customizing treatment strategies to fit each individual's distinct circumstances. Hope Rising accommodates clients of all genders, fostering a welcoming and inclusive environment. For those looking for effective addiction treatment with a custom approach, this facility is committed to supporting you on your journey toward sustained recovery.

Hope Rising Outpatient
Saint George, UT

Situated in Saint George, UT, Hope Rising Outpatient specializes in comprehensive outpatient services, including intensive outpatient and day treatment for individuals grappling with substance use issues. The center offers various therapeutic modalities such as 12-step facilitation, anger management, and brief interventions, catering to both adult and young adult clients across all gender identities. Emphasizing personalized care, Hope Rising Outpatient is recognized for creating tailored treatment strategies that address the specific needs of each client. The facility's dedication to delivering high-quality care and well-rounded programs renders it an excellent option for individuals in search of effective and supportive addiction treatment within a nurturing atmosphere.

Hope Rising Residential

Situated in New Harmony, UT, Hope Rising Residential specializes in providing extensive treatment for substance use challenges among adults and young adults within a nurturing atmosphere. The center offers various residential options, including long-term, short-term, and 24-hour care, all designed to cater to individual needs. Their approach combines 12-step facilitation, anger management, and brief intervention techniques to create effective treatment plans. With a commitment to personalized care, Hope Rising Residential assists both men and women in their recovery paths, ensuring each client receives the quality support they require for lasting change.

Hope Valley Recovery
Circleville, OH

Hope Valley Recovery, located in Circleville, OH, provides a wide range of services aimed at treating addiction. These services encompass detoxification, substance use programming, transitional housing, and sober living arrangements. The center features hospital-based inpatient detox services and specializes in therapies such as 12-step support, anger management, and cognitive behavioral approaches. Additionally, the facility offers tailored programs for adult men and women, including support for those affected by intimate partner violence. With a commitment to delivering exceptional care, this center serves both adult and young adult clients of all genders in a nurturing and encouraging environment to aid in their recovery process.

Hope by the Sea
San Juan Capistrano, CA

Situated in San Juan Capistrano, CA, "Hope by the Sea" delivers an extensive array of substance abuse recovery programs tailored for both adults and young adults. This center is particularly adept at addressing co-occurring disorders and significant mental health challenges, including emotional issues in minors. The facility offers various levels of care such as intensive outpatient programs, outpatient day services, and partial hospitalization. Treatment methods include 12-step language, anger management strategies, and brief intervention techniques. "Hope by the Sea" also features specialized tracks for men, women, and individuals who have faced domestic violence, ensuring that it meets the diverse requirements of its clients. With its gender-specific treatment offerings, the center provides individualized attention, establishing itself as a leading option for effective rehabilitation.

Hope by the Sea
San Juan Capistrano, CA

Hope by the Sea in San Juan Capistrano, CA, delivers thorough addiction treatment for adults and young adults. The center features extended residential stays, detox services, and round-the-clock residential care. They focus on dual diagnoses involving substance abuse and significant mental health conditions. Treatment methods are personalized and include 12-step support, anger management techniques, and brief intervention strategies. Specialized tracks are available for adult men, adult women, and those who have faced intimate partner violence. Committed to high standards of care, Hope by the Sea guides individuals toward lasting recovery.

Hope by the Sea
San Juan Capistrano, CA

Nestled in San Juan Capistrano, CA, Hope by the Sea provides extensive recovery programs for adults. This center focuses on detox, addiction treatment, and dual diagnosis for adults with significant mental health conditions, as well as for children experiencing emotional distress. Offering long-term residential, detox residential, and round-the-clock residential care, the facility incorporates 12-step facilitation, anger management techniques, and brief intervention strategies. Hope by the Sea serves adult men and women, including survivors of intimate partner violence. Their specialized young adult programs are designed for personalized attention and assistance.

Hope House Treatment Center

Hope House Treatment Center, located in Crownsville, MD, provides a wide array of services for individuals dealing with substance abuse and concurrent mental health issues. The center features inpatient detoxification services and treatment, offering tailored programs for adult men, adult women, and those who have faced partner violence. By emphasizing 12-step methods, anger management, and brief intervention strategies, this facility meets the distinct requirements of both adults and young adults. Hope House Treatment Center is committed to delivering quality care and personalized treatment plans, making it a reliable option for individuals on their journey to recovery and wellness.

Hope on Haven Hill
Rochester, NH

Hope on Haven Hill in Rochester, NH, delivers targeted care for adult women struggling with substance use, including those who are pregnant or postpartum, and individuals facing co-occurring severe mental health conditions. The center offers various levels of care, such as hospital inpatient, round-the-clock inpatient, and intensive outpatient programs, incorporating therapeutic strategies like 12-step facilitation and anger management. They also emphasize brief intervention techniques and provide options for transitional living. Personalized treatment plans are available for adults, seniors, and young adults, ensuring each individual receives appropriate support. Emphasizing a women-centered approach, Hope on Haven Hill cultivates a nurturing atmosphere for women on their journey to recovery from addiction and mental health concerns.

Hope Valley Inc
Pilot Mountain, NC

Situated in Pilot Mountain, NC, Hope Valley Inc delivers exceptional treatment for substance use in a round-the-clock residential environment. This center is known for its specialization in 12-step programs, anger management, and brief intervention techniques. Aimed primarily at adult women, the services are available for adults of all ages, including seniors and young adults. The facility fosters a nurturing atmosphere exclusively for women, ensuring tailored support to aid in recovery. Hope Valley Inc's short-term residential services are specifically structured to address the distinct challenges faced by women struggling with addiction. For those in search of dedicated care within an empathetic setting, this center is committed to guiding you on your path to recovery.

Hope Valley Inc
Dobson, NC

Situated in Dobson, NC, Hope Valley Inc specializes in high-quality rehabilitation services for adult males dealing with substance use issues. This center delivers long-term, residential care around the clock, utilizing methods such as 12-step facilitation, anger management, and brief intervention. Emphasizing transitional housing and sober living, Hope Valley Inc serves a diverse clientele that includes adults, seniors, and young adults. With a dedicated environment exclusively for men, this facility guarantees tailored support and care, assisting individuals as they navigate their recovery journey. Opt for Hope Valley Inc for thorough and effective treatment within a secure and well-organized atmosphere.

Hope House Inc
Roxbury, MA

Hope House Inc, located in Roxbury, MA, provides extensive long-term residential care for adult men struggling with addiction and accompanying mental health challenges. This center is particularly adept at supporting individuals who have endured relationship violence or sexual trauma. Employing methods like 12-step integration, emotional regulation techniques, and cognitive restructuring, the program prioritizes personalized support for lasting recovery. Offering options for continued housing, Hope House Inc serves adult men, including older adults and young adults, with a program specifically designed for their distinct needs.

Hope House Inc
Augusta, GA

Hope House Inc, located in Augusta, GA, provides extensive treatment for substance use alongside support for individuals facing significant mental health challenges or emotional issues. The center features a range of treatment offerings, which include intensive outpatient programs, extended residential care, and standard outpatient services. It also has specialized programs designed for active duty military members, adult women, and survivors of intimate partner violence, addressing a variety of individual needs. The facility employs a variety of therapeutic methods such as 12-step programs, anger management, and cognitive behavioral therapy, ensuring customized care for adults, seniors, and young adults. With a specific focus on women's services, Hope House Inc prioritizes high-quality care in a nurturing atmosphere conducive to successful recovery.

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Laguna Hills, CA

Hope by the Sea, situated in Laguna Hills, CA, provides a variety of treatment options for adults and young adults dealing with substance use issues, particularly those facing concurrent mental health challenges. It features both short-term and long-term residential programs designed specifically for men and women, including support for individuals who have been affected by domestic violence. The treatment strategy includes methodologies like 12-step facilitation, anger management, and brief intervention, ensuring care is customized to meet each person's unique needs. This center fosters a nurturing environment conducive to recovery for all genders. Discover exceptional care and thorough treatment at Hope by the Sea.

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Albany, NY

Hope House Inc located in Albany, NY, provides long-term residential rehabilitation geared towards adult women dealing with substance use, transitional living, and co-existing mental health issues. The center fosters a nurturing atmosphere and features specialized programs aimed at individuals who have faced intimate partner violence, domestic violence, or sexual trauma. Treatment methods utilized include cognitive behavioral therapy, anger management, and the Matrix Model. Catering specifically to adults, seniors, and young adults, this facility prioritizes high-quality care with a gender-sensitive approach that addresses the distinct requirements of its female clientele. Hope House Inc stands as a symbol of support for those in pursuit of thorough and empathetic recovery services.

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Albany, NY

Hope House Inc located in Albany, NY, provides targeted rehabilitation services for individuals grappling with substance use issues and concurrent mental health conditions, catering to both adults and youth. Their therapeutic offerings encompass intensive outpatient programs, standard outpatient treatment, and options for methadone or buprenorphine administration. Utilizing proven methodologies such as cognitive behavioral therapy and motivational interviewing, Hope House Inc delivers thorough support for men, women, children, and teenagers alike. Prioritizing tailored care, this center addresses the unique requirements of each client, ensuring effective assistance for those on the path to overcoming addiction and mental health difficulties.

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Hope House Inc, located in Troy, NY, provides a variety of services for individuals dealing with substance use issues in a nurturing setting. The facility features extensive outpatient therapy, long-term residential treatment, and outpatient services, employing methods like cognitive behavioral therapy and motivational interviewing. Offering tailored programs for teenagers, adult males, and adult females, it accommodates a wide spectrum of clients. Hope House Inc serves both adults and the elderly, delivering individualized support for everyone. Residents have access to transitional housing, halfway houses, and sober living options, making the path to recovery inclusive and thorough. Opt for Hope House Inc for exceptional care and customized treatment solutions.

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Hope House Inc, located in Troy, NY, provides extensive programs for substance abuse recovery. They offer extended stay in a secure and nurturing setting, emphasizing 12-step integration, emotional regulation techniques, and short-term counseling to meet diverse client requirements. This center focuses its specialized support on adult women, older adults, and younger adults who have faced domestic abuse. Additionally, Hope House Inc extends its services to active military members in need of recovery assistance. Their dedication to high-quality treatment ensures individuals can attain enduring abstinence.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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