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Medically Reviewed Content
Updated: September 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Northern Nevada Hopes

Northern Nevada Hopes, situated in Reno, NV, delivers extensive substance abuse rehabilitation services for both adults and children grappling with concurrent mental health issues. The center offers various treatment modalities, including intensive outpatient care, outpatient services, and options like methadone, buprenorphine, or naltrexone. Their therapeutic strategies feature 12-step programs, brief interventions, and cognitive behavioral therapy. This facility serves adult men, women, and those affected by domestic violence, providing dedicated support to individuals of all genders, including seniors, in a nurturing environment aimed at fostering recovery and overall wellness.

Northern Ohio Recovery Association

Situated in Cleveland, Ohio, the Northern Ohio Recovery Association delivers an extensive array of treatment options for individuals dealing with substance use challenges, including services for both adults and minors. The center offers intensive outpatient care, long-term residential support, and standard outpatient programs, emphasizing therapeutic methods like cognitive behavioral therapy, anger management, and short intervention strategies. Specialized programs are available for adolescents, adult males, and adult females, allowing for customized treatment plans tailored to each person's needs. With its committed team of experts, the center provides high-quality support for clients of all genders aiming to recover from substance use disorders alongside related mental health conditions.

Northern Pines Mental Health Center

Northern Pines Mental Health Center, located in Wadena, MN, provides a variety of evidence-supported treatment options for individuals facing substance use issues and co-occurring mental health conditions, serving both adults and children. The center features intensive outpatient, outpatient, and standard outpatient programs that employ cognitive behavioral therapy, motivational interviewing, and strategies to prevent relapse. It also has specialized services for clients with dual diagnoses. Northern Pines Mental Health Center is inclusive, welcoming individuals of all genders, and emphasizes customized care for every patient. This facility is recognized as a reliable source for those in need of thorough rehabilitation support.

Northern Pines Mental Health Center

Situated in Little Falls, MN, Northern Pines Mental Health Center delivers targeted treatment for adults and young adults facing substance use issues alongside concurrent mental health challenges. Emphasizing methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, the center offers a range of programs, including intensive outpatient, outpatient, and standard outpatient options. Designed to accommodate both genders, this facility is particularly proficient in meeting the intricate needs of clients with dual diagnoses. Northern Pines Mental Health Center is recognized for its thorough methodology in addressing substance use disorders in conjunction with serious psychological conditions or emotional issues, guaranteeing top-notch care for individuals on their path to recovery.

Northlake Behavioral Health System

Situated in Mandeville, LA, Northlake Behavioral Health System delivers a wide range of rehabilitation services tailored for both adults and children. The center specializes in detoxification, treatment for substance use disorders, and managing co-occurring conditions, offering 24/7 inpatient care. The program features 12-step facilitation, strategies for anger management, and brief interventions. With services geared towards active duty military members and adults of all genders, Northlake Behavioral Health System serves a variety of demographics. Their customized approach and specialized programs for various age groups and genders ensure high-quality support and care for individuals on their path to recovery from addiction and mental health issues.

Northpoint Recovery

Northpoint Recovery in Meridian, ID, provides extensive care for adults and young adults struggling with addiction and related mental health challenges. They offer inpatient hospital detoxification and treatment, with tailored options for active military, adult men, and adult women. Employing methods such as 12-step facilitation, anger management, and brief intervention, Northpoint Recovery serves all genders. Their commitment to high-quality, personalized treatment aims to support individuals in attaining sustained recovery and enhanced mental health.

Northstar Recovery Center

Northstar Recovery Center, situated in Southborough, MA, provides thorough addiction treatment for both adults and young adults. This center excels in addressing dual diagnoses, treating substance use disorders concurrently with significant mental health conditions in adults and emotional challenges in children. Employing strategies such as 12-step support, emotional regulation techniques, and short-term counseling, Northstar offers intensive outpatient, standard outpatient, and partial hospitalization programs. Specialized care is available for active military personnel, as well as distinct programs for adult men and women, ensuring a personalized recovery journey. Northstar's dedication to high standards of care and customized treatment plans positions it as a leading option for individuals pursuing successful recovery.

Northern Pines Mental Health Center

Situated in Aitkin, MN, Northern Pines Mental Health Center provides extensive treatment for substance use and targeted support for those facing dual mental health challenges. The center offers a range of programs, including intensive outpatient, outpatient, and standard outpatient services for both adults and younger individuals. By implementing evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, the facility customizes treatment plans to address the specific needs of each client. Northern Pines Mental Health Center is recognized for its specialized offerings for those dealing with both mental health and substance use disorders, delivering exceptional care to clients of all genders pursuing recovery.

Northstar Recovery Center
West Springfield, MA

Northstar Recovery Center, located in West Springfield, MA, provides extensive care for substance misuse in adults and younger adults, including those with concurrent mental health issues. Their program offerings include intensive outpatient services, day treatment, and partial hospitalization. The center is equipped to support specific groups such as active military personnel, adult men, and adult women. By employing methods like 12-step facilitation, anger management strategies, and brief intervention techniques, Northstar delivers personalized treatment plans. They are dedicated to offering high-quality support for individuals facing addiction and dual diagnosis concerns, serving both male and female clients.

Northwell Health
West Hempstead, NY

Situated in West Hempstead, NY, Northwell Health delivers extensive treatment options for adults dealing with substance use issues, with a focus on those facing co-existing mental health challenges and emotional issues in children. Their outpatient services feature customized strategies including cognitive behavioral therapy and motivational incentives. The center offers specific care for adult men and women, as well as clients who have undergone trauma, ensuring a tailored recovery experience. Northwell Health is committed to providing exceptional treatment to adults and young adults of all genders, utilizing outpatient services, methadone/buprenorphine, and naltrexone programs, all designed to address unique individual requirements with empathy and professionalism.

Northern Pines Mental Health Center

Northern Pines Mental Health Center, located in Brainerd, MN, delivers tailored care for individuals grappling with addiction and co-occurring mental health conditions across all age groups. The center's offerings encompass intensive outpatient and standard outpatient services, which include medication-assisted treatment with methadone and buprenorphine. Employing proven therapeutic methods such as cognitive behavioral therapy and motivational interviewing, alongside robust relapse prevention techniques, Northern Pines serves both male and female patients. The facility places a particular emphasis on supporting adolescents and those with dual diagnoses, providing thorough support aimed at fostering enduring recovery and enhancing overall health for everyone they serve.

Northern Valley Indian Health Inc

Northern Valley Indian Health Inc, situated in Willows, CA, delivers extensive substance use care for individuals of all ages, particularly those facing concurrent severe mental health challenges. Their services include outpatient treatment options, such as methadone and buprenorphine programs, alongside therapeutic interventions like 12-step encouragement and emotional regulation training. The center features specialized offerings for young people, adult men, and women. Committed to serving a diverse adult and senior population of all genders, this establishment prioritizes personalized, top-tier treatment. Utilizing proven therapeutic methods in a nurturing atmosphere, Northern Valley Indian Health Inc is devoted to guiding individuals toward sustained well-being.

Northern Valley Indian Health Inc

Situated in Chico, CA, Northern Valley Indian Health Inc delivers extensive substance abuse rehabilitation services for both adults and children facing concurrent significant mental health challenges. The center offers outpatient care options, including treatments with methadone/buprenorphine and naltrexone, along with standard outpatient therapy sessions. It features specialized programs tailored for teenagers, as well as adult men and women, addressing a variety of community needs. By employing techniques such as 12-step facilitation, anger management, and brief intervention strategies, the center focuses on providing customized care. Dedicated to serving adults and seniors of all genders, this facility emphasizes quality treatment and personalized recovery plans aimed at fostering enduring healing.

Northstar Health Systems

Situated in Bayonne, NJ, Northstar Health Systems provides an extensive array of services for addiction rehabilitation. The facility is focused on detoxification and treatment for substance use disorders among both adults and young adults. Offering various programs, including intensive outpatient services and outpatient detox, Northstar Health Systems addresses the needs of those pursuing recovery. The center features specialized programs tailored for adolescents, men, and women, ensuring that each person's care is customized to their specific needs. Their treatment methods incorporate strategies such as 12-step facilitation, anger management, and brief intervention, all aimed at facilitating comprehensive recovery. Northstar Health Systems is dedicated to offering exceptional care within a nurturing atmosphere.

Northpointe Council Inc

Northpointe Council Inc, located in Lockport, NY, provides extensive care for substance use disorders via multiple outpatient options, including methadone and buprenorphine services. Their treatment modalities are grounded in proven methods such as cognitive behavioral therapy and anger management techniques. This center distinguishes itself with specific services designed for distinct populations, including active duty military personnel, teenagers, and adult men. Catering to a broad spectrum of individuals, from adults to children and adolescents of any gender, Northpointe Council Inc ensures personalized support for a wide array of requirements. The dedication to high-quality treatment and customized recovery plans positions Northpointe Council Inc as a premier facility for those pursuing successful and nurturing addiction recovery.

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Situated in Bemidji, Minnesota, the Northern MN Addiction Wellness Center provides a thorough approach to substance use recovery through its long-term and around-the-clock residential treatment programs. The facility emphasizes 12-step methodologies, anger management, and cognitive behavioral techniques. Tailored programs are available for adult men, women, and individuals who have faced issues related to intimate partner or domestic violence. Catering to both adults and young adults of all genders, the center delivers personalized care and scientifically-supported strategies to aid clients on their recovery path. Prioritizing high standards and specialized services, the Northern MN Addiction Wellness Center is a reliable option for effective addiction rehabilitation.

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Manchester Center, VT

Situated in Manchester Center, VT, Northshire UCS provides extensive treatment options for substance use aimed at both adults and children grappling with concurrent severe mental health challenges. The center offers a variety of programs, including intensive outpatient, standard outpatient, and outpatient services, all designed to meet individual needs through methods such as 12-step facilitation, anger management, and brief interventions. There are specialized programs available for adolescents, as well as dedicated services for adult men and women. Northshire UCS is committed to delivering high-quality care and personalized treatment strategies, focusing on fostering long-term recovery and overall wellness for adults and seniors of any gender. For those in search of effective and tailored rehabilitation options in Vermont, this center stands out as a dependable resource.

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Northstar Behavioral Health Network, situated in Fergus Falls, MN, stands as a leading addiction recovery center dedicated to assisting adult men in overcoming substance dependency. This establishment provides diverse care modalities, encompassing hospital-level inpatient services, extended residential stays, and round-the-clock residential support. Emphasizing methodologies such as 12-step program integration, emotional regulation strategies, and short-term counseling, the center delivers customized assistance for individuals managing coexisting mental health and addiction challenges. Northstar Behavioral Health Network is equipped to serve adult and younger adult males, fostering a nurturing atmosphere conducive to healing. Discover exceptional support and individualized recovery plans at this respected institution.

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Situated in Far Rockaway, NY, Northwell Hlth LI Jewish Med Ctr provides focused treatment for adults dealing with substance use issues alongside significant mental health challenges, as well as support for children affected by serious emotional difficulties. This center offers outpatient services that include therapies with methadone, buprenorphine, or naltrexone. It emphasizes approaches such as anger management, brief interventions, and cognitive behavioral therapy, addressing the needs of both adult men and women, including those with trauma histories. With dedicated programs for both adults and youth, the facility ensures personalized and effective care for all clients on their path to recovery.

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Situated in Fort Supply, OK, the Northwest Center for Behavioral Health delivers extensive detoxification services for both adults and adolescents. This center features inpatient detox programs and around-the-clock hospital services. Emphasizing strategies like anger management, brief intervention, and cognitive behavioral therapy, it adapts its methods to meet the distinct requirements of each individual. The facility also offers specialized programs for men and women, prioritizing personalized treatment to assist every client in their recovery journey. If you seek a committed center that emphasizes high-quality, tailored care, the Northwest Center for Behavioral Health could be the ideal option for you.

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Situated in Woodward, OK, the Northwest Center for Behavioral Health specializes in outpatient services for individuals dealing with substance abuse and dual mental health issues in both adults and children. This center emphasizes personalized treatment, employing methods such as anger management, cognitive behavioral therapy, and short-term interventions. It aims to provide tailored support to adults and seniors of varied backgrounds. The Northwest Center for Behavioral Health also delivers outpatient options for methadone/buprenorphine or naltrexone therapy alongside standard outpatient programs, ensuring comprehensive care for those on their journey to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated September 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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