Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.
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Spero Health in Morehead, KY, extends outpatient recovery services to adults of all genders, with particular consideration for individuals affected by domestic abuse. The facility caters to young adults and older individuals, utilizing therapeutic modalities like anger management, cognitive behavioral therapy, and brief intervention. Recognizing diverse needs, Spero Health provides individualized treatment through outpatient medication management with methadone, buprenorphine, or naltrexone, alongside standard outpatient programs. A key feature of this center is its commitment to gender-specific care and holistic support for those on their journey to overcome substance dependency.

Spero Health, situated in Paducah, KY, stands as a complete facility for substance use recovery, providing outpatient care. Services encompass medication-assisted treatment with methadone or buprenorphine, evidence-based therapies like cognitive behavioral therapy, strategies for managing anger, and short-term interventions. The center offers tailored programs designed for adult men and women, and for individuals affected by intimate partner or domestic violence. Spero Health serves adults and young adults across the gender spectrum, emphasizing personalized support and care. By prioritizing effective treatment modalities and customized plans, Spero Health is committed to guiding individuals toward lasting sobriety.

Spero Health, situated in Lexington, KY, provides accessible outpatient care for individuals facing substance use challenges. Their therapeutic offerings encompass crucial areas like anger management, cognitive behavioral therapy, and brief intervention strategies. The center is dedicated to supporting specific populations, including adult men and women, as well as those impacted by intimate partner or domestic violence. Spero Health extends its comprehensive services to adults and young adults across all gender identities, delivering effective treatment options such as outpatient methadone, buprenorphine, or naltrexone, alongside regular outpatient programs. Through a commitment to personalized treatment plans and proven, evidence-based methods, Spero Health strives to guide individuals toward sustained wellness and recovery.

Spero Health located in Martinsville, VA, specializes in outpatient treatment for substance use disorders among adults and young adults. The center offers a variety of treatment options, including outpatient services with methadone/buprenorphine or naltrexone, standard outpatient programs, and multiple therapeutic techniques such as anger management, brief interventions, and cognitive behavioral therapy. Spero Health implements specialized programs designed for adult men and women, in addition to those who have faced intimate partner or domestic violence, addressing a wide array of needs. The facility prioritizes personalized care to deliver effective treatment for everyone. As a reliable resource for both male and female clients, Spero Health is dedicated to facilitating thorough addiction recovery.

Spero Health, situated in Danville, KY, stands as a premier provider of outpatient recovery services focused on addiction treatment. Their offerings encompass medication-assisted treatment options such as methadone, buprenorphine, and naltrexone, alongside standard outpatient care. The center also integrates targeted therapeutic interventions, including strategies for managing anger, brief counseling approaches, and cognitive behavioral therapy. Spero Health extends its support to adults of all genders, including those affected by domestic or intimate partner violence, ensuring a holistic and empathetic approach to facilitate lasting recovery.

Spero Health in Galax, VA, offers extensive support for substance use disorders via personalized outpatient services. This center provides medication-assisted treatment (methadone/buprenorphine/naltrexone) alongside standard outpatient care. They also feature distinct programs for adult men, adult women, and individuals affected by intimate partner or domestic violence, ensuring a broad spectrum of support. Employing scientifically validated methods such as anger management, brief intervention, and cognitive behavioral therapy, Spero Health assists adults and young adults across the gender spectrum in achieving lasting recovery. Discover a caring and results-driven approach to rehabilitation at Spero Health.

Situated in Elizabethtown, Kentucky, Spero Health delivers outpatient care for individuals struggling with substance use disorders. Their services include medication-assisted treatment options like methadone, buprenorphine, and naltrexone, alongside comprehensive outpatient programs. Spero Health employs therapeutic strategies such as anger management, brief intervention, and cognitive behavioral therapy to address a range of client needs. The center serves adult men and women, including those impacted by domestic or intimate partner violence. Prioritizing a high standard of care, this establishment crafts personalized recovery plans tailored to each person's unique path.

Spero Health in Chattanooga, TN, delivers multifaceted substance use recovery services for adults and young adults managing co-occurring mental health challenges. Their offerings include intensive outpatient, outpatient, and specialized medication-assisted treatment options utilizing methadone, buprenorphine, or naltrexone. Emphasizing 12-step facilitation, anger management techniques, and brief intervention strategies, the center customizes treatment to each person's unique situation. They also feature dedicated programs for active military personnel, adult men, and adult women, providing focused assistance. Spero Health welcomes both male and female patients, ensuring professional and effective care. For those pursuing impactful addiction treatment within a nurturing setting, this center provides individualized plans for sustained recovery.

Spero Health in Marietta, OH, provides a full spectrum of care for substance use disorders, including intensive outpatient, outpatient, and medication-assisted treatment options like methadone, buprenorphine, and naltrexone. Their expertise extends to anger management, brief intervention strategies, and cognitive behavioral therapy. Spero Health also offers specialized programs tailored for adult men, adult women, and individuals who have faced intimate partner or domestic violence. Catering to adults and young adults across all gender identities, the facility fosters a nurturing atmosphere conducive to healing. Emphasizing personalized treatment plans and scientifically-backed methods, Spero Health in Marietta is committed to guiding clients toward sustained recovery and improved quality of life.

Spero Health, situated in Warren, OH, delivers a wide range of treatment options for substance use disorders, designed to meet the unique requirements of each individual. The center specializes in intensive outpatient care, outpatient programs, and medication-assisted treatments with methadone, buprenorphine, or naltrexone. Spero Health employs various therapeutic methods, including cognitive behavioral therapy, anger management, and brief interventions, to address the needs of adult clients, including those affected by intimate partner or domestic violence. Aiming to provide exceptional care for both men and women, this facility is dedicated to offering a supportive and professional setting for those pursuing recovery from addiction.

Spero Health, situated in Dublin, VA, specializes in outpatient programs aimed at treating substance use disorders with an emphasis on high-quality, evidence-based care. The center offers various treatment options, including methadone/buprenorphine or naltrexone outpatient services, standard outpatient care, and diverse therapeutic techniques such as anger management, brief intervention, and cognitive behavioral therapy. Spero Health accommodates adult clients, including men and women, as well as those who have faced intimate partner or domestic violence. This facility is committed to delivering personalized and extensive rehabilitation services to assist individuals of all genders, both adults and young adults, on their path to recovery.

Spero Health, located in Middlesboro, KY, provides extensive support for substance use disorders through accessible outpatient services, featuring medication-assisted treatment with methadone, buprenorphine, or naltrexone. Their approach incorporates proven therapeutic techniques like anger management, cognitive behavioral therapy, and brief intervention to foster successful addiction recovery. This center welcomes adult men and women, with specific attention given to those who have faced intimate partner or domestic violence. They extend their services to both adults and young adults, tailoring care to suit different age demographics and genders. Spero Health prioritizes high-quality, personalized treatment plans, committed to guiding individuals toward overcoming addiction and securing enduring sobriety.

Spero Health, situated in Elyria, OH, provides complete care for substance use disorders, featuring intensive outpatient, standard outpatient, and medication-assisted treatment options including methadone, buprenorphine, and naltrexone. Their expertise extends to specialized therapies such as anger management, brief intervention strategies, and cognitive behavioral therapy. The center offers tailored programs for adult men, adult women, and individuals affected by intimate partner or domestic violence. Spero Health is committed to delivering personalized support for adults and young adults of all genders, ensuring each person receives care aligned with their distinct recovery needs. Employing a dedication to high standards and proven therapeutic methods, this facility empowers individuals on their path to lasting recovery.

Spero Health, situated in Hazard, KY, delivers outpatient care for individuals battling substance use disorders. Their services are designed for adults and young adults, with tailored programs addressing the unique needs of men, women, and those impacted by domestic or intimate partner violence. Treatment methodologies employed include anger management, brief interventions, and cognitive behavioral therapy. Spero Health provides medication-assisted treatment options such as methadone, buprenorphine, or naltrexone, alongside standard outpatient services. The center is committed to delivering high-quality, individualized rehabilitation plans for all clients seeking recovery.

Spero Health, located in Cookeville, TN, specializes in outpatient treatment for substance abuse, emphasizing tailored care for each individual. The center offers a range of services, including outpatient programs for methadone/buprenorphine or naltrexone, standard outpatient therapy, anger management sessions, brief interventions, and cognitive behavioral therapy. It features specialized programs designed for adult men, women, and individuals who have faced intimate partner or domestic violence. Catering to both adults and young adults of any gender, this facility fosters a caring atmosphere for those pursuing recovery from addiction. With its dedication to high-quality care, Spero Health is recognized for its all-encompassing approach to rehabilitation, making it an excellent option for individuals seeking substance abuse treatment.

Spero Health, located in Frankfort, KY, specializes in outpatient treatment for substance use aimed at both adults and young adults. This center offers a variety of targeted services such as outpatient treatments with methadone, buprenorphine, or naltrexone, alongside additional support for anger management, brief interventions, and cognitive behavioral therapy. Emphasizing personalized care, the facility provides programs tailored for adult men, women, and those who have suffered from intimate partner or domestic violence. Spero Health maintains an inclusive atmosphere for all clients, prioritizing their needs. For those in search of effective addiction treatment delivered with empathy, this center is committed to supporting your recovery process.

Situated in Beckley, West Virginia, Spero Health delivers accessible, outpatient care for individuals grappling with substance use disorders. Their services include medication-assisted treatment utilizing methadone, buprenorphine, or naltrexone, alongside comprehensive outpatient programs. Therapies offered encompass anger management, brief intervention strategies, and cognitive behavioral approaches. Spero Health is equipped to support adult men and women, including those who have faced intimate partner or domestic violence. By offering targeted programs for diverse groups, the center prioritizes personalized recovery plans. Their commitment to high-quality care and a holistic approach establishes Spero Health as a leading provider of effective and empathetic addiction recovery services.

Spero Health, situated in Roanoke, VA, delivers extensive outpatient services for substance use treatment, featuring options such as methadone/buprenorphine or naltrexone. The center caters to both adult men and women, and is equipped to support clients who have faced domestic or intimate partner violence. Treatment methods encompass anger management, short interventions, and cognitive behavioral therapy. Spero Health is dedicated to providing tailored care and quality assistance for adults and young adults, regardless of gender, who are on the path to recovery from addiction.

Spero Health located in Coshocton, OH, provides outpatient treatment for substance use, featuring services like methadone/buprenorphine or naltrexone treatment along with general outpatient care. The center employs various strategies including anger management, brief intervention, and cognitive behavioral therapy. It offers specialized programs designed for adult men and women, as well as those who have faced intimate partner or domestic violence. Spero Health welcomes adults and young adults from all genders, ensuring that each client receives individualized care that meets their specific requirements. Committed to using evidence-based methods and maintaining high standards of treatment, this center strives to assist clients on their recovery paths with care and professionalism.

Situated in Gallipolis, OH, Spero Health stands out as a leading rehabilitation center focused on treatment for substance use disorders. The center provides outpatient services, including methadone, buprenorphine, and naltrexone therapies, alongside traditional outpatient programs. Spero Health also incorporates various therapeutic methods such as anger management and cognitive behavioral therapy, serving adult individuals, including those affected by intimate partner or domestic violence. Catering to all genders, Spero Health emphasizes personalized treatment strategies and utilizes evidence-based practices to ensure quality care. For those in search of supportive and effective addiction recovery options, this center is committed to facilitating your path to healing.

Situated in Erlanger, KY, Spero Health stands out as a premier center for substance use recovery, providing outpatient treatments such as methadone, buprenorphine, or naltrexone, alongside standard outpatient services. The facility incorporates various evidence-based methodologies, including cognitive behavioral therapy, anger management, and brief interventions. Spero Health offers dedicated programs for adult men and women, as well as individuals impacted by domestic or intimate partner violence. This center caters to adults and young adults across all genders, emphasizing a tailored approach to meet unique recovery requirements. For those in search of thorough addiction treatment within a nurturing atmosphere, Spero Health is an excellent choice for personalized rehabilitation solutions.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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