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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Tigard Comprehensive Treatment Center

Tigard Comprehensive Treatment Center in Portland, OR, delivers outpatient care for individuals struggling with substance use, serving adults and young adults. Services include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside regular outpatient programs. Therapeutic interventions such as anger management, brief intervention, and cognitive behavioral therapy are integrated. The center also features specialized programs for adult men, adult women, and those who are pregnant or postpartum. Emphasizing tailored support, Tigard Comprehensive Treatment Center is committed to offering exceptional, individualized recovery assistance within an inclusive setting for all clients.

Toiyabe Indian Health Project

The Toiyabe Indian Health Project in Bishop, CA, provides extensive addiction treatment for adults and older adults. Services include various outpatient options such as methadone, buprenorphine, or naltrexone treatment, alongside general outpatient care. Their approach incorporates proven methods like contingency management, motivational interviewing, and relapse prevention strategies. Dedicated programs exist for teenagers and individuals affected by sexual trauma. This center emphasizes personalized support for both men and women, fostering a welcoming setting for those on their recovery journey.

Tomah VAMC
Tomah, WI

Tomah VAMC located in Tomah, Wisconsin delivers extensive addiction recovery services for both adults and young adults. The center features hospital-based detox programs, comprehensive substance abuse treatment, and transitional living arrangements such as halfway houses and sober living facilities. With dedicated programs for various populations, including active duty service members, adult men, and adult women, this facility customizes its treatment to meet diverse needs. By employing methods like anger management, brief interventions, and cognitive behavioral therapy, Tomah VAMC guarantees quality support for all clients. If you are looking for effective rehabilitation in a nurturing atmosphere, this center is dedicated to guiding you on your journey to recovery.

Top of the World Ranch

Top of the World Ranch, situated in Milan, IL, delivers a full spectrum of recovery support for adults and young adults struggling with addiction and concurrent mental health challenges. Their treatment options include intensive outpatient, extended residential stays, and standard outpatient care. The center utilizes evidence-based therapies such as 12-step integration, emotional regulation training, and rapid intervention strategies. They also offer specialized services for active military members, adult men, and adult women, demonstrating a dedication to gender-specific needs. Top of the World Ranch is recognized for its dedication to high-quality, supportive recovery, positioning it as a leading provider of effective and empathetic addiction therapy.

Topsail Addiction Treatment Inc

Topsail Addiction Treatment Inc, situated in North Andover, MA, delivers extensive services for individuals facing substance use challenges, including both adults and young adults. The center offers various treatment formats, such as intensive outpatient programs, regular outpatient services, and day treatment options like partial hospitalization. Emphasizing methods like 12-step facilitation, anger management, and short intervention strategies, Topsail Addiction Treatment serves diverse populations, including active duty military members and both men and women. The facility is inclusive and committed to providing personalized care that meets the distinct requirements of each client. If you are looking for expert addiction support in a nurturing atmosphere, Topsail Addiction Treatment is ready to assist you.

Torn Counseling and Recovery Center

The Torn Counseling and Recovery Center in Acworth, GA, provides expert care for adults struggling with addiction and co-occurring mental health conditions, alongside support for children facing emotional challenges. They offer various outpatient services, including intensive options, delivering personalized treatment plans that incorporate strategies such as anger management, brief intervention, and cognitive behavioral therapy. Dedicated programs are available for teenagers, adult men, and women, ensuring specific needs are met. This center welcomes individuals of all genders and ages, from children to adults, and is committed to delivering high-quality, evidence-based therapeutic interventions to guide them toward lasting recovery.

Total Healthcare Inc

Total Healthcare Inc, located in Baltimore, MD, delivers thorough outpatient care for individuals struggling with substance use issues. The center excels in addressing dual diagnoses involving substance use disorders alongside significant mental health conditions in adults or emotional challenges in young people. They employ personalized treatment strategies, incorporating techniques like brief intervention, cognitive behavioral therapy, and motivational interviewing. Total Healthcare Inc designs its programs to meet the specific requirements of each client, offering high-quality services to all genders. The facility emphasizes customized strategies for successful recovery, whether clients require standard outpatient services or medication-assisted treatment using methadone, buprenorphine, or naltrexone.

Townhall II
Kent, OH

Townhall II, located in Kent, OH, provides targeted substance use rehabilitation services catering to adults as well as children and adolescents. The center emphasizes intensive outpatient and standard outpatient treatment options, offering medications like methadone, buprenorphine, or naltrexone for those on their recovery journey. By employing proven methods such as anger management techniques, cognitive behavioral therapy, and motivational interviewing, Townhall II customizes its treatment strategies to fit the individual needs of each client. Moreover, the center features specialized programs tailored for adolescents and individuals who have faced intimate partner violence, domestic violence, or sexual abuse. Dedicated to delivering high-quality care, Townhall II serves all genders, fostering a welcoming atmosphere for anyone looking to overcome addiction challenges.

Touch Angels Behav Healthcare LLC

Touch Angels Behav Healthcare LLC in Gilbert, AZ, is dedicated to providing comprehensive care for adults and children facing various challenges. Their services address substance use disorders, co-occurring mental health conditions, and serious emotional disturbances in young individuals. The center offers flexible living arrangements, including extended stays, shorter programs, and round-the-clock residential care, all tailored to individual needs. Treatment modalities employed include 12-step facilitation, anger management techniques, and brief intervention strategies. Specific support is available for adult women, survivors of intimate partner violence, domestic abuse, and sexual assault. Touch Angels Behav Healthcare LLC is committed to delivering high-quality, personalized treatment that fosters recovery and overall well-being for individuals of all ages and genders.

TLC Treatment Center

TLC Treatment Center, situated in Mesa, Arizona, provides an extensive range of services for individuals dealing with substance use issues, including options for transitional housing and sober living. The center features intensive outpatient care alongside outpatient and partial hospitalization programs. Emphasizing 12-step support, anger management, and brief therapeutic interventions, it serves both adult men and women, as well as those who have faced sexual abuse. TLC Treatment Center focuses on adults and young adults, offering gender-specific programming tailored for both sexes. With a strong dedication to delivering high-quality care and personalized treatment plans, this center is committed to assisting clients throughout their recovery process.

Total Healthcare Inc

Total Healthcare Inc., located in Baltimore, MD, delivers extensive outpatient services for individuals of all ages grappling with substance use disorders and co-occurring mental health challenges. Employing strategies such as brief intervention, cognitive behavioral therapy, and motivational interviewing, the center offers personalized care plans for adults and young adults. Their expertise includes outpatient treatment with methadone, buprenorphine, and naltrexone, serving both male and female patients. Total Healthcare Inc. is distinguished by its commitment to customizing treatment, guaranteeing that every person gets the specific assistance vital for successful rehabilitation.

Towns Health Services

Situated in Galt, CA, Towns Health Services presents a variety of rehabilitation programs tailored for adults and adolescents facing substance use challenges alongside mental health disorders. The center specializes in intensive outpatient therapy, day outpatient treatment, and partial hospitalization, employing methods like 12-step support, anger management, and brief intervention strategies. Towns Health Services features specialized programs designed for active military personnel, men, and women, addressing the needs of a broad audience. The facility is dedicated to providing personalized care and assistance for both male and female participants, making it an excellent option for individuals in pursuit of effective and tailored addiction recovery solutions.

Towns Health Services/Lodi

Towns Health Services/Lodi in Lodi, CA provides expert care for individuals facing challenges with substance use. Their services are comprehensive, addressing co-occurring substance use disorders and serious mental health conditions in adults, as well as serious emotional disturbances in children. The center offers various levels of care, including intensive outpatient, outpatient, and partial hospitalization programs. Utilizing proven methods like 12-step facilitation, anger management, and brief intervention, they support adult men and women, alongside active duty military members. Towns Health Services/Lodi is dedicated to delivering effective treatment to adults and young adults, tailoring interventions to each person's unique needs through evidence-based strategies.

Touchette Regional Hospital
East Saint Louis, IL

Touchette Regional Hospital, located in East Saint Louis, IL, delivers a wide array of services aimed at treating addiction for both adults and young adults. The facility specializes in hospital inpatient detox and provides round-the-clock care for those struggling with substance use disorders and related mental health issues. Emphasizing personalized treatment, Touchette employs various evidence-based methodologies, including anger management, brief interventions, and cognitive behavioral therapy. The center is distinguished by its customized programs that cater to the specific requirements of every individual. Both men and women can receive exceptional care in a nurturing and therapeutic setting at this center.

Tidewater Psychotherapy Services

Situated in Virginia Beach, VA, Tidewater Psychotherapy Services delivers targeted substance use recovery programs for adults and young adults facing significant mental health challenges or emotional issues. Emphasizing personalized treatment, this facility offers intensive outpatient options in addition to outpatient care using methadone, buprenorphine, or naltrexone. Incorporating techniques such as 12-step support, anger management, and brief interventions, the center serves both men and women. For those in search of thorough addiction recovery solutions with a customized focus, Tidewater Psychotherapy Services is dedicated to offering high-quality support to aid your journey towards healing.

Timberline Knolls

Timberline Knolls, located in Lemont, IL, provides extensive long-term residential treatment for women facing challenges related to substance use and concurrent mental health issues. Catering to adult women, teenagers, and active military personnel, this center employs proven treatment methods, including 12-step facilitation and cognitive behavioral therapy. With an emphasis on fostering a nurturing atmosphere conducive to recovery, Timberline Knolls features residential detox services and round-the-clock care customized to meet each person's needs. This center is distinguished by its dedication to high-quality treatment and specifically designed programs for women aiming for enduring recovery and rehabilitation.

Touchstone Short Term Residential

Touchstone Short Term Residential, situated in Lincoln, NE, specializes in providing residential treatment for substance use. The center offers round-the-clock support for both adults and young adults, with programs specifically designed for men, women, and those who have faced trauma. Emphasizing strategies such as 12-step guidance, anger management, and brief intervention, Touchstone Short Term Residential delivers thorough care for individuals pursuing recovery. Its dedication to high-quality therapy and gender-sensitive treatment choices for all clients distinguishes it as a caring and efficient option for short-term residential rehabilitation needs.

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Situated in Owego, NY, Tioga County Mental Hygiene provides focused outpatient services for individuals struggling with substance use and co-occurring issues in both adults and youth. Emphasizing brief interventions, cognitive behavioral therapy, and the Matrix Model, this center delivers personalized care designed to meet unique requirements. Their specialized programs are aimed at those with dual diagnoses, promoting comprehensive and integrative treatment. Tioga County Mental Hygiene offers outpatient options for methadone, buprenorphine, or naltrexone, catering to male and female clients alike, with a steadfast dedication to delivering high-quality rehabilitation support.

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Situated in Sells, AZ, the Tohono Oodham Dept of Health and Human offers thorough substance use recovery programs for both adults and children facing significant mental health challenges. The center provides various levels of care, including intensive outpatient therapy, day treatment, and partial hospitalization options. With a focus on serving adolescents, adult men, and women, it is equipped to assist individuals of all ages and backgrounds. Incorporating techniques such as 12-step support, anger management strategies, and brief therapeutic interventions, this facility aims to provide exceptional care for adults and seniors on their path to recovery. If you or someone you know is seeking personalized rehabilitation services, this center creates a nurturing and efficient atmosphere for healing.

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North Babylon, NY

The Town of Babylon rehabilitation center, situated in North Babylon, NY, delivers dedicated care for adults struggling with substance misuse and co-occurring psychological conditions, as well as for children experiencing emotional distress. Through its outpatient offerings, such as methadone/buprenorphine therapy, the center incorporates 12-step facilitation, anger management strategies, and brief intervention services. Specially designed programs for teenagers, adult men, and women ensure that each individual receives personalized support. The facility serves a broad demographic, accommodating both adult and young male and female clients. Recognized for its thorough treatment strategies and high standards of care, the Town of Babylon facility distinguishes itself through its wide array of therapeutic choices and dedication to complete personal wellness.

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Smithtown, NY

The Town of Smithtown rehabilitation center, situated in Smithtown, NY, delivers comprehensive outpatient substance use disorder treatment. Their specialized services include 12-step facilitation, anger management, and brief intervention strategies, serving adults and young people of all gender identities. The center also offers distinct programs designed for adolescents, adult males, and adult females, facilitating personalized care pathways. In addition to standard outpatient services, they provide medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. The Town of Smithtown rehabilitation center is committed to delivering high-caliber support for individuals pursuing lasting sobriety.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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