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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Townsend Recovery Center

Townsend Recovery Center, located in Covington, LA, provides a wide array of addiction recovery services designed for both adults and young adults. The center facilitates detox programs, treatment for substance use disorders, and offers targeted assistance for individuals dealing with simultaneous substance use and serious mental health challenges. Various treatment options are available, including intensive outpatient care, long-term residential stays, and outpatient services, ensuring that different needs are met. Emphasizing a comprehensive recovery process, Townsend Recovery Center incorporates 12-step support, anger management techniques, and short-term interventions. With specialized programs for men, women, and individuals who have faced trauma, the center showcases its dedication to personalized treatment. Townsend Recovery Center is committed to delivering high-quality care, focusing on helping clients achieve lasting sobriety.

Tranquil Shores
Saint Petersburg, FL

Tranquil Shores, situated in Saint Petersburg, FL, specializes in a wide range of rehabilitation services aimed at adults and young adults confronting substance abuse and simultaneous mental health challenges. The center offers intensive outpatient therapy, day treatment programs, and partial hospitalization options, employing methods like 12-step support, anger management techniques, and brief therapeutic interventions. To cater to specific needs, Tranquil Shores includes targeted programs for active military members and both male and female adults, ensuring personalized treatment for everyone. Dedicated to delivering high-quality care, this facility emphasizes a holistic approach to recovery, guiding clients toward sustainable wellness.

Tranquility Woods LLC

Tranquility Woods LLC, located in Pasadena, MD, presents a variety of targeted treatment options for both adults and young adults facing challenges with substance use disorders as well as related mental health issues. This center delivers a full range of services, including inpatient detoxification and treatment services in a hospital setting, emphasizing approaches like 12-step programs, anger management, and brief interventions. Specific programs are designed for active duty service members, as well as specialized support for adult men and women. Tranquility Woods LLC is devoted to offering high-quality care in a nurturing environment, ensuring that individuals pursuing recovery receive personalized attention and support tailored to their unique circumstances. The facility fosters a safe and empathetic atmosphere conducive to healing.

Transformations at Mending Fences LLC

Transformations at Mending Fences LLC in Morriston, FL provides thorough addiction recovery services and dedicated support for those facing concurrent serious mental health conditions or emotional distress. This center offers extended residential stays, outpatient care, and day treatment programs, employing methods like 12-step encouragement, impulse control training, and rapid intervention strategies. Featuring distinct programs for active military members, adult males, and adult females, the facility serves adults and young adults across all gender identities. Transformations at Mending Fences LLC is devoted to offering superior, personalized attention to aid individuals in their path toward healing.

Transformations by the Gulf
Saint Petersburg, FL

Nestled in Saint Petersburg, FL, Transformations by the Gulf is a premier addiction recovery facility serving adults and young adults. They provide a spectrum of care, including intensive outpatient, outpatient, and partial hospitalization programs. The center's therapeutic approach incorporates 12-step facilitation, anger management, and brief intervention strategies, addressing the needs of adult men and women, including those with trauma histories. Transformations by the Gulf delivers personalized recovery plans, making it a distinguished choice for effective and caring substance use disorder treatment.

Transformations Treatment Center Inc

Transformations Treatment Center Inc, located in Delray Beach, FL, delivers a range of rehabilitation services including intensive outpatient, outpatient, and day treatment specifically designed for individuals dealing with substance abuse and concurrent mental health issues. The center features dedicated programs aimed at active duty military personnel as well as separate tracks for adult men and women. Clients benefit from various therapeutic methods such as 12-step support, anger management, and brief intervention strategies. Suitable for adults and young adults of all genders, this facility prioritizes personalized care and employs evidence-based techniques to foster a comprehensive recovery experience. Transformations Treatment Center Inc is recognized for its emphasis on high-quality care and extensive support, making it an excellent option for those in search of effective rehabilitation solutions within the Delray Beach community.

Transition House Inc
Saint Cloud, FL

Transition House Inc, located in Saint Cloud, FL, provides extensive treatment options for adult men, seniors, and young adults struggling with substance use. With expertise in handling co-occurring substance use and significant mental health challenges, this center offers a variety of programs, including long-term, short-term, and 24-hour residential services. Utilizing personalized strategies such as 12-step engagement and anger management, the facility is well-equipped to assist active duty military members and individuals facing challenges related to intimate partner violence. Transition House Inc prioritizes high-quality care through targeted interventions and customized treatment plans. If you are looking for effective rehabilitation that addresses multifaceted needs, this center is committed to aiding you on your path to recovery.

Transitions Center

Transitions Center, situated in Tempe, AZ, specializes in outpatient addiction recovery services, including detox, substance use therapy, and integrated care for those facing concurrent mental health and substance use challenges. They utilize evidence-based methods like motivational interviewing and leverage telemedicine/telehealth to deliver methadone, buprenorphine, or naltrexone treatment. Their personalized programs are designed for adolescents, adult men, and adult women, serving all genders from young adults to seniors. Transitions Center is recognized for its thorough approach and dedication to personalized treatment plans, positioning it as a leading facility for effective and empathetic addiction support.

Transitions Inc
Fort Mitchell, KY

Transitions Inc, situated in Fort Mitchell, KY, offers an extensive range of services for substance use treatment along with specialized support for those facing both substance use disorders and severe mental health challenges. The center provides various programs, including long-term, short-term, and residential options, incorporating evidence-based strategies like 12-step facilitation, anger management, and brief interventions. With unique programs designed for active duty military members, adult men and women, Transitions Inc serves a diverse population of adults and young adults. This facility is dedicated to delivering high-quality care and personalized treatment plans to assist individuals in their recovery journey.

Transformations Care Inc

Transformations Care Inc, located in Gardena, CA, delivers thorough addiction recovery programs, encompassing both detox and ongoing substance abuse treatment. Prioritizing hospital-level inpatient care and round-the-clock availability, this establishment supports adults and young adults across all gender identities. The center distinguishes itself with tailored interventions like 12-step support, emotional regulation training, and custom-fit treatment strategies, ensuring each person receives uniquely suited assistance. Transformations Care Inc is recognized for its dedication to superior care and customized recovery journeys, establishing it as a premier destination for effective and empathetic addiction treatment in the Gardena community.

Transcendence Treatment Center LLC

Transcendence Treatment Center LLC, located in North Charleston, SC, delivers extensive addiction recovery services for adults and young adults. They feature intensive outpatient, standard outpatient, and day treatment programs. The center utilizes personalized care strategies, including anger management, brief intervention, and cognitive behavioral therapy. Designed for individual needs, their programs welcome both men and women. Transcendence Treatment Center LLC is committed to providing excellent care and guiding individuals toward lasting sobriety.

TPC Substance Use Outpatient Services

Situated in Amarillo, TX, TPC Substance Use Outpatient Services delivers focused outpatient care for individuals dealing with substance use issues and overlapping mental health conditions in both adults and children. The center employs strategies such as brief intervention, cognitive behavioral therapy, and community reinforcement in conjunction with vouchers to offer customized assistance to its clients, regardless of gender. Prioritizing individualized care, TPC Substance Use Outpatient Services is designed for adults and young adults who are in search of thorough support in an outpatient setting. If you or someone you know is in need of effective substance use treatment that emphasizes a tailored approach, this center is committed to facilitating a successful recovery journey.

Transformations Health Services

Transformations Health Services in Cincinnati, OH provides extensive addiction recovery and tailored support for individuals facing dual diagnoses of substance abuse and significant mental health challenges, as well as for children with emotional disruptions. Their structured intensive outpatient and outpatient services, which may involve medication-assisted treatment such as methadone, buprenorphine, or naltrexone, are designed to meet distinct patient requirements. By offering counseling for substance use disorders and incorporating virtual care via telemedicine, the facility guarantees customized support. Emphasizing a personalized strategy, they assist both adults and young individuals of all genders, delivering targeted interventions. Transformations Health Services is dedicated to high standards of care, establishing itself as a trusted provider of successful addiction treatment.

TPC Wellness
Jackson, OH

TPC Wellness, located in Jackson, OH, is dedicated to providing targeted substance use treatment specifically for adult males. This center features a variety of programs including intensive outpatient, outpatient, and day treatment formats. Emphasizing methods like 12-step facilitation, anger management, and cognitive behavioral therapy, TPC Wellness ensures that clients receive the attention they need. While primarily serving adult men, the facility also accommodates adult women and individuals living with HIV or AIDS, offering customized care to meet different requirements. Catering to adults, seniors, and young adults alike, this center focuses on delivering high-quality, personalized treatment strategies. For those in search of an inclusive addiction recovery program with an emphasis on male participants, TPC Wellness provides a nurturing space for healing and growth.

Transformation Healthcare Inc

Situated in Baltimore, MD, Transformation Healthcare Inc delivers targeted rehabilitation programs for both adults and young adults struggling with substance abuse issues and simultaneous mental health disorders. The center offers a range of treatment options such as intensive outpatient programs, outpatient services, and day treatment, all customized to meet the unique requirements of clients. Emphasizing 12-step support, anger management, and brief intervention techniques, the facility serves active duty military members as well as adult men and women. With a commitment to providing exceptional care for all clients, Transformation Healthcare Inc is distinguished by its all-encompassing programs aimed at fostering recovery and overall wellness.

Transformation Wellness Center

Situated in Klamath Falls, OR, the Transformation Wellness Center delivers extensive treatment programs for adults and young adults facing substance use challenges. This center specializes in intensive outpatient care, standard outpatient services, and offers methadone/buprenorphine or naltrexone therapy. Employing techniques such as anger management, the Matrix Model, and motivational interviewing, the center customizes its services to meet the unique needs of each client. With a commitment to personalized attention, the center serves both men and women who are seeking assistance on their path to recovery. For those in search of a facility that prioritizes tailored treatment and high-quality support, the Transformation Wellness Center is ready to assist.

Transformations Wellness Center

Transformations Wellness Center is situated in Klamath Falls, Oregon, and specializes in long-term residential treatment for substance use in an encouraging atmosphere. This facility offers transitional housing and sober living arrangements for adults of both genders. Emphasizing 12-step principles, anger management, and cognitive behavioral therapy, the program serves adults and young adults in need of thorough addiction rehabilitation. The center features tailored programs for men and women to ensure personalized care and attention. Transformations Wellness Center is committed to delivering effective treatment and assistance to individuals embarking on their recovery journey.

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Mount Orab, OH

TPC Wellness, situated in Mount Orab, OH, stands out as a leading rehabilitation facility focused on substance use recovery for adult males. The center offers a variety of programs including intensive outpatient treatment, traditional outpatient services, and daytime treatment options, all designed to foster a nurturing recovery atmosphere. Their approach integrates 12-step principles, anger management techniques, and cognitive behavioral therapy to meet the diverse needs of clients. TPC Wellness serves adult men, seniors, and young adults, with specialized programs available for those living with HIV or AIDS, as well as individuals facing dual mental health challenges. Renowned for its exceptional care and personalized treatment strategies, this center is committed to guiding individuals on their journey toward enduring sobriety.

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Ironton, OH

Situated in Ironton, OH, TPC Wellness is a prominent rehabilitation facility focused on providing substance use treatment specifically for adult women. The center offers various programs, including intensive outpatient, outpatient, and day treatment services, employing proven methods like 12-step facilitation, cognitive behavioral therapy, and anger management. TPC Wellness is distinguished by its targeted programs for adult women, as well as individuals living with HIV or AIDS and those facing dual diagnoses involving mental health and substance use issues. Catering to adults, seniors, and young adults, the center delivers holistic care designed to meet the distinct needs of female clients, ensuring effective treatment and support.

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San Diego, CA

Tradition One, situated in San Diego, CA, delivers long-term residential treatment for adult males dealing with substance use issues. This center features transitional housing within a halfway house framework, emphasizing anger management, cognitive behavioral therapy, and motivational interviewing techniques. Tradition One is particularly adept at helping clients who have faced intimate partner violence, domestic violence, and sexual abuse, catering to men of all ages, including seniors and young adults. The facility focuses on tailored care and evidence-based methods, ensuring clients receive the support they need on their recovery path. For those looking for a thorough and nurturing atmosphere to tackle substance use disorders, Tradition One in San Diego is recognized for its specialized programs and high-quality care.

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Transformation Healthcare Inc, located in Columbia, MD, specializes in the treatment of substance abuse and co-occurring mental health disorders for adults facing significant psychological challenges, as well as for children experiencing emotional issues. The facility offers a range of treatment modalities, including intensive outpatient programs, outpatient services, and day treatment options. By employing 12-step facilitation, anger management techniques, and concise intervention strategies, the center customizes its programs to fit the specific requirements of each client. Focusing on a personalized care model, Transformation Healthcare Inc caters to adults and young adults of all genders. Committed to providing exceptional care within a nurturing atmosphere, the center aims to support individuals as they navigate their recovery journey.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)