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Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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United Health Services Hospitals Inc

Situated in Binghamton, NY, United Health Services Hospitals Inc delivers extensive treatment for substance use through its inpatient programs. The center ensures round-the-clock care within a hospital setting, utilizing specialized methods like 12-step support, brief interventions, and motivational interviewing. Designed to address the unique requirements of each patient, this facility serves adults and young adults across all genders. With an emphasis on high-quality care and customized treatment strategies, United Health Services Hospitals Inc is dedicated to assisting individuals as they navigate their path to recovery in a nurturing and empowering atmosphere.

United Health Services Hospitals Inc

United Health Services Hospitals Inc in Binghamton, NY, provides extensive addiction care for adults facing mental health challenges and for children with emotional difficulties. Their services encompass intensive outpatient, standard outpatient, and medication-assisted treatments like methadone, buprenorphine, and naltrexone. The center also features distinct programs for active military personnel, teenagers, and adult men, accommodating various patient groups. Therapeutic methods employed include facilitating 12-step participation, anger control training, and brief intervention strategies. Accepting both male and female patients, this institution delivers effective rehabilitation tailored to individual needs.

Unity Hospital of Rochester

Unity Hospital of Rochester, located in Rochester, NY, provides outpatient services focusing on detoxification and the treatment of substance use disorders. The center emphasizes anger management, brief interventions, and cognitive behavioral therapy, offering personalized care to adult men and women, as well as clients dealing with both mental health issues and substance use disorders. Unity Hospital serves a diverse population, including both adults and minors, accommodating patients of all genders. Its outpatient detox and treatment programs with methadone, buprenorphine, or naltrexone are designed to support comprehensive recovery efforts. Committed to high-quality, individualized care, Unity Hospital of Rochester aims to assist patients in achieving enduring sobriety.

Unity Hospital of Rochester

Unity Hospital of Rochester, located in Rochester, NY, delivers outpatient services for individuals of all ages grappling with substance use and co-occurring mental health conditions. Their therapeutic methods encompass anger management, cognitive behavioral therapy, and brief intervention strategies. Tailored programs are available for adolescents, adult men, and adult women, with specialized gender-specific care designed to meet unique requirements. Emphasizing high standards and scientifically supported methods, Unity Hospital offers outpatient treatment using methadone, buprenorphine, or naltrexone, in addition to general outpatient services to foster lasting recovery and well-being.

Unity Hospital of Rochester

Unity Hospital, based in Rochester, NY, delivers a wide array of addiction rehabilitation services for both adults and children. The facility specializes in outpatient detox, treatment for substance use disorders, and therapy for those with concurrent mental health conditions. Emphasizing techniques like anger management and cognitive behavioral therapy, Unity Hospital supports clients who have faced trauma. Tailored programs are designed for adult men and women, along with individuals pursuing assistance for substance abuse and mental health challenges. The center ensures high-quality care for those seeking outpatient treatment with methadone, buprenorphine, or naltrexone. Unity Hospital of Rochester is committed to guiding individuals on their journey toward recovery.

Unity Hospital of Rochester

Unity Hospital of Rochester, located in Rochester, NY, offers a wide range of treatment options for substance use disorders, including specialized support for those facing both substance use and significant mental health issues. The center provides outpatient services, featuring programs such as methadone and buprenorphine treatment, and employs proven strategies like cognitive behavioral therapy and motivational interviewing to aid in the recovery process. Catering to adult men and women, as well as individuals who have undergone trauma, the programs are designed to address the specific requirements of each client. Unity Hospital of Rochester is dedicated to providing high-quality care in a nurturing and empathetic atmosphere for adults and youth of all genders.

University of Alabama at Birmingham

The University of Alabama at Birmingham, situated in Birmingham, AL, provides a wide range of rehabilitation services aimed at adults and seniors dealing with substance use issues and associated mental health challenges. This center offers intensive outpatient programs, as well as standard outpatient services, and features special initiatives designed for trauma survivors. Emphasizing techniques such as cognitive behavioral therapy, motivational interviewing, and contingency management, the facility serves a diverse clientele, including men, women, adolescents, and adult females. By utilizing evidence-based practices and personalized treatment plans, the center strives to deliver exceptional care to individuals embarking on their recovery paths.

University of Colorado Denver/ARTS

The University of Colorado Denver/ARTS, situated in Arvada, CO, provides targeted programs for substance use recovery aimed at adults and young adults. This center features intensive outpatient care, as well as outpatient services that include methadone, buprenorphine, or naltrexone treatments. Emphasizing anger management, concise intervention, and cognitive-behavioral therapy, the facility serves adult men and women along with individuals who have faced traumatic experiences. With customized programs for each gender, the University of Colorado Denver/ARTS is committed to delivering quality care and extensive support for those in need of effective and personalized addiction recovery solutions.

University Behavioral Center

University Behavioral Center, located in Orlando, FL, delivers an extensive range of services for detoxification and substance use disorders, with a focus on adults facing severe co-occurring mental health conditions and children dealing with emotional issues. The center features hospital inpatient care for detoxification and related treatments, providing around-the-clock support. Utilizing customized methods such as 12-step programs, anger management, and short intervention strategies, the facility supports active military personnel, men, and survivors of intimate partner violence. Catering to both adults and children/adolescents of any gender, University Behavioral Center is committed to offering top-notch care and individualized treatment plans to assist individuals in their recovery process.

University Hospital/Stony Brook ELIH

Situated in Riverhead, NY, University Hospital/Stony Brook ELIH delivers an extensive array of treatment solutions for individuals battling substance use disorders. It includes transitional living arrangements and addresses overlapping mental health issues for both adults and children. The center provides outpatient care, featuring methadone and buprenorphine therapy, alongside cognitive behavioral therapy. It emphasizes specialized programs in anger management, brief intervention, and tailored support for teens, adult women, and those with co-existing disorders, welcoming both male and female clients. Prioritizing quality and personalized care strategies, this facility stands out as a reliable option for individuals in need of effective rehabilitation services.

University of California San Francisco

University of California San Francisco, situated in San Francisco, California, delivers complete addiction recovery services for adults and adolescents. This institution is particularly adept at addressing dual diagnoses, managing substance use disorders concurrently with significant mental health conditions or developmental/emotional challenges in youth. Their offerings encompass outpatient treatment, including medication-assisted therapies with methadone, buprenorphine, or naltrexone, alongside standard outpatient support. Employing strategies such as brief intervention, cognitive behavioral therapy, and motivational interviewing, the center ensures personalized care plans. Distinct programs are available for adult men, adult women, and individuals with a history of trauma. The facility's commitment to high-quality, research-backed rehabilitation extends to specialized support for both genders.

University of Arkansas for

The University of Arkansas Rehabilitation Center, situated in Little Rock, AR, provides tailored outpatient programs for both adults and young adults grappling with substance use disorders and concurrent serious mental health issues. Emphasizing personalized treatment, this center offers a range of services, including 12-step initiatives, anger management classes, and brief intervention strategies. Distinctive programs are available for adult men and women, as well as individuals who have undergone sexual trauma. The center also provides outpatient treatment options using methadone/buprenorphine or naltrexone, ensuring that both male and female clients receive top-notch care. If you seek customized and efficient rehabilitation services, this facility is committed to aiding you on your path to recovery.

United Counseling Service of

United Counseling Service in Bennington, VT, delivers complete care for individuals facing substance use issues, especially those with concurrent serious mental health conditions or emotional difficulties in young people. This institution offers robust outpatient services, including specialized programs for adolescents, adult males, and females, and provides medication-assisted treatment options such as methadone, buprenorphine, or naltrexone. Their approach is personalized, incorporating methods like 12-step facilitation, anger management, and brief interventions. United Counseling Service is dedicated to offering excellent, customized support to adults and seniors of all genders on their journey to overcoming addiction and mental health struggles.

United Memorial Medical Center

United Memorial Medical Center in Batavia, NY, provides extensive inpatient care for substance use disorders. This facility offers specialized support for adults and young adults, welcoming individuals of all gender identities, including those in the LGBTQ+ community. Their therapeutic approaches include anger management, brief intervention strategies, and cognitive behavioral therapy, all adapted to each person's unique situation. United Memorial Medical Center stands as a dedicated provider of high-quality, inclusive inpatient rehabilitation in Batavia, NY.

United Services Inc
Mansfield Center, CT

Situated in Mansfield Center, CT, United Services Inc offers outpatient treatment for substance use aimed at adults and young adults. With a focus on co-occurring substance use disorders along with significant mental health challenges, the center provides tailored care through methods such as cognitive behavioral therapy and anger management strategies. Their programs are designed for both men and women, creating an all-encompassing and supportive treatment environment. Committed to a personalized approach, United Services Inc emphasizes the delivery of exceptional care through both regular outpatient services and outpatient treatments that include methadone/buprenorphine or naltrexone options. For those seeking effective and customized addiction treatment, this center is devoted to aiding your path to recovery.

Unity Place of Monmouth County LLC

Unity Place of Monmouth County LLC, located in Oceanport, NJ, delivers thorough addiction recovery services and tailored support for adults facing concurrent serious mental health conditions, as well as for children with emotional challenges. The center offers robust outpatient programs, including intensive day treatment and partial hospitalization, employing methodologies like 12-step integration, emotional regulation techniques, and rapid intervention strategies. Committed to personalized recovery paths, the facility provides specialized tracks for adult men and women, alongside support for survivors of domestic or intimate partner abuse. Catering to adults and older adults of every gender, this establishment prioritizes excellent care within a nurturing setting.

United Services Inc

At United Services Inc in Dayville, CT, adults and young adults receive complete outpatient care for substance use. The center is particularly adept at addressing dual diagnoses, where substance use disorders intersect with significant mental health challenges or emotional distress. Treatment plans are tailored to each individual and incorporate therapies like anger management, cognitive behavioral therapy, and brief interventions. Additionally, outpatient services for medication-assisted treatment, including methadone, buprenorphine, or naltrexone, are available. United Services Inc welcomes both male and female clients, fostering a welcoming atmosphere for everyone pursuing effective rehabilitation.

United Summit Center
Clarksburg, WV

United Summit Center, located in Clarksburg, WV, delivers intensive outpatient and outpatient services aimed at addressing substance use and concurrent mental health issues for both adults and children. The center employs methods like anger management and cognitive behavioral therapy to offer personalized treatment for individuals of all ages and genders. With an emphasis on high-quality, customized care, this facility is distinguished by its focused programs and wide-ranging services, including treatments with methadone/buprenorphine and naltrexone. For individuals in search of empathetic and effective addiction recovery solutions, United Summit Center creates a nurturing atmosphere conducive to healing and restoration.

University of Alabama at Birmingham

Nestled in Birmingham, AL, the University of Alabama at Birmingham provides extensive substance abuse recovery programs for adults and emerging adults. Their expertise lies in addressing co-occurring substance use disorders and severe mental health conditions. Services include intensive outpatient programs, standard outpatient care, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The center employs strategies like 12-step facilitation, anger management, and brief intervention, serving both men and women, including trauma survivors. Renowned for its excellent standards, this institution is a premier destination for those desiring tailored support within a nurturing setting.

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Cherry Hill, NJ

Situated in Cherry Hill, NJ, Unity Place provides an extensive array of rehabilitation services for individuals facing challenges related to substance use disorders alongside mental health issues. This center features intensive outpatient programs, day treatment options, and partial hospitalization tailored for both adults and young adults. Emphasizing 12-step support, anger management techniques, and brief intervention strategies, Unity Place is particularly attentive to the needs of adult women and individuals who have gone through trauma. By focusing on those with co-occurring mental health and substance use conditions, the center is dedicated to delivering high-quality care for all clients on their path to recovery.

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Situated in Hammonton, NJ, Unity Place of Atlantic County LLC provides focused rehabilitation services for both adults and young adults experiencing substance use issues alongside mental health challenges. The center features intensive outpatient programs, daytime outpatient treatment, and partial hospitalization, all grounded in evidence-based methods like 12-step facilitation, anger management, and cognitive behavioral therapy. Unity Place is dedicated to assisting individuals who have faced trauma, including intimate partner violence, domestic abuse, and sexual assault. Emphasizing high-quality care, this facility serves both male and female clients in pursuit of thorough and empathetic treatment.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)