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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.

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Center
Edmonds, WA

Situated in Edmonds, WA, the Center provides outpatient programs for substance use recovery, catering to adult men and women, including those facing concurrent mental health challenges. The treatment framework incorporates proven methods like anger management, cognitive behavioral therapy, and motivational interviewing. Designed for adults and young adults alike, this center offers tailored support for both sexes. Emphasizing personalized care and high standards, the Center aims to assist clients in their path to recovery. If you are looking for thorough and efficient addiction treatment in a supportive atmosphere, this facility is committed to guiding you towards enduring sobriety and enhanced wellness.

Center for Addiction Treatment

Situated in Cincinnati, OH, the Center for Addiction Treatment delivers an extensive array of services designed to assist individuals on their path to recovery. With a focus on detoxification and treatments for substance use, this center offers a variety of programs, including intensive outpatient, outpatient, and outpatient detox options. Emphasizing methods such as 12-step facilitation, anger management, and brief interventions, the facility customizes its programs to cater to adults and young adults of every gender. A distinguishing feature of this center is its commitment to a personalized care approach, ensuring that each client receives the specific support they need throughout their recovery journey. If you or someone you know is in search of effective addiction treatment, the Center for Addiction Treatment is committed to guiding you toward sustainable recovery.

Center for Behavioral Health Iowa

Situated in Davenport, IA, the Center for Behavioral Health Iowa delivers outpatient care for substance use issues, emphasizing treatments like methadone, buprenorphine, or naltrexone. The facility also offers standard outpatient services along with diverse strategies such as anger management, brief interventions, and cognitive behavioral therapy. This center features dedicated programs for adult males and females, accommodating both adults and younger adults. With a focus on high-quality care and a variety of customized services, the Center for Behavioral Health Iowa stands out as a supportive option for those pursuing effective and individualized treatment for addiction in the Davenport region.

Center for Behavioral Health

Situated in Amesbury, MA, the Center for Behavioral Health specializes in treating adults and young adults who are facing substance use challenges alongside significant mental health conditions. The center offers a range of outpatient services, which include anger management, cognitive-behavioral therapy, and short-term interventions. With specifically designed programs for adult men, adult women, and those who have experienced trauma, the center focuses on delivering individualized care for each client. It also provides outpatient treatment options such as methadone/buprenorphine or naltrexone, in addition to consistent outpatient programs, addressing a variety of needs. Committed to offering exceptional care and guidance, this facility strives to support individuals in their recovery journey.

Center for Behavioral Health
North Charleston, SC

Situated in North Charleston, SC, the Center for Behavioral Health provides an extensive array of outpatient services focused on detoxification and treatment for substance use disorders. The offerings encompass outpatient detox as well as treatment with methadone, buprenorphine, or naltrexone. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, this center supports active duty military members, adult males, and adult females. Catering to adults and young adults of all genders, the Center for Behavioral Health delivers personalized care designed to meet the specific requirements of individuals, guaranteeing effective treatment for those on the path to addiction recovery.

Center for Addictive Problems

Situated in Chicago, IL, the Center for Addictive Problems provides targeted outpatient programs designed for those in need of detoxification and substance use disorder treatment. The center offers outpatient detox services along with treatment options that include methadone, buprenorphine, or naltrexone. Their methods incorporate 12-step facilitation, brief interventions, and cognitive behavioral therapy. Emphasizing personalized care, this facility serves adults and young adults of every gender. The Center for Addictive Problems is distinguished by its customized treatment plans and dedication to providing exceptional addiction recovery services in a nurturing setting.

Center for Behavioral Health

The Center for Behavioral Health, situated in Las Vegas, NV, provides focused outpatient care for adults struggling with addiction and concurrent mental health challenges, as well as children experiencing emotional difficulties. Their services employ a variety of proven methods, such as techniques for managing anger, cognitive behavioral therapy, and motivational incentives. The center caters to specific needs with customized plans for adult men and women, those affected by domestic violence or intimate partner violence, and survivors of such abuse. With a commitment to offering top-tier care in a nurturing setting, the center supports adults and young adults across the gender spectrum. For extensive outpatient support, including medication-assisted treatment like methadone or buprenorphine, the Center for Behavioral Health stands as a reliable source for effective and empathetic healing.

Center for Addictions
Springfield, MO

Nestled in Springfield, MO, the Center for Addictions delivers thorough support for those battling addiction. This establishment features hospital-based inpatient detox, continuous hospital inpatient services, and rigorous outpatient options. Employing methods like 12-step encouragement, emotional regulation, and concise counseling, the center supports adults and young people facing concurrent mental health issues. Unique programs are offered for those who have experienced trauma or are dealing with pain alongside substance dependence. Prioritizing individualized attention and scientifically validated methods, this center crafts customized recovery journeys for all clients, regardless of gender, aiming to overcome addiction.

Center for Behavioral Health Idaho Inc

Situated in Meridian, ID, the Center for Behavioral Health Idaho Inc provides outpatient detox and treatment services for substance use aimed at both adults and young adults. This center offers tailored care for adult men, women, and those who are pregnant or in the postpartum phase. Employing methods such as brief intervention, cognitive behavioral therapy, and community reinforcement with vouchers, it delivers high-quality, gender-sensitive treatment. Committed to personalized care, this facility serves male and female clients in need of effective addiction support within a nurturing atmosphere.

Center for Behavioral Health Idaho Inc

The Center for Behavioral Health Idaho Inc, situated in Boise, ID, provides outpatient services for detoxification and addiction recovery. This center is dedicated to assisting adult men, adult women, pregnant or postpartum women, and young adults. Their treatment methods encompass brief intervention strategies, cognitive behavioral therapy, and a community reinforcement approach supplemented with vouchers. The facility emphasizes delivering high-quality care and offers distinct programs tailored for both male and female patients. For those in search of thorough addiction treatment within a supportive outpatient environment, this center offers personalized programs designed to address individual requirements.

Center for Alcohol and Drug Services

The Center for Alcohol and Drug Services in Davenport, IA, delivers complete addiction recovery support. This establishment features dedicated services such as detox programs, comprehensive substance abuse therapy, supervised living arrangements, and extended care housing. Employing inpatient hospital treatment models and varied methodologies like 12-step integration and emotional regulation techniques, the center serves adult individuals of all genders, as well as those affected by trauma. Personalized plans for adolescents and adults guarantee unique treatment journeys. The center's dedication to high-standard care and gender-focused programs establishes it as a reliable destination for individuals pursuing freedom from addiction.

Center for Behavioral Health
North Las Vegas, NV

Based in North Las Vegas, NV, the Center for Behavioral Health specializes in thorough outpatient detox and treatment programs for substance use. The center employs proven methodologies, including cognitive behavioral therapy and anger management, to offer tailored support to adult men, women, and young adults dealing with simultaneous mental health and substance use issues. Emphasizing personalized treatment strategies and motivational incentives, the facility fosters a nurturing atmosphere conducive to recovery. This program serves clients of all genders, providing exceptional care aimed at helping individuals attain sustainable sobriety and enhanced mental health.

Center for Behavioral Health
North Las Vegas, NV

The Center for Behavioral Health in North Las Vegas, NV, provides expert outpatient therapy for addiction and related mental health conditions. They have diverse services for adults and young adults, such as anger management, CBT, and motivational incentives. The center also features special programs for men, women, and survivors of domestic abuse. Committed to excellent, personalized care, the Center for Behavioral Health guides clients toward lasting recovery. They offer complete support for various needs, from standard outpatient services to methadone/buprenorphine treatment.

Center for Behavioral Health

The Center for Behavioral Health in Reno, NV, provides outpatient support for adults struggling with addiction, including individuals also managing significant mental health conditions. The center excels in addressing dual diagnoses with targeted strategies like anger management, brief interventions, and cognitive behavioral therapy. Customized treatment plans are developed for adult men, adult women, and young adults facing challenges with both substance use and mental well-being. Committed to high standards of care, the facility offers medication-assisted treatment with methadone, buprenorphine, or naltrexone, integrated with their general outpatient services. Clients receive thorough assistance within a professional and supportive setting.

Center for Behavioral Health Inc

Situated in Tucson, AZ, the Center for Behavioral Health Inc delivers targeted programs for the treatment of substance use disorders aimed at both adults and young adults. This center specializes in outpatient services, which include methadone/buprenorphine or naltrexone therapy, regular outpatient care, and a variety of evidence-backed interventions such as cognitive behavioral therapy, anger management, and motivational incentives/contingency management. Emphasizing personalized care, the center provides specialized programs for adult males, adult females, and individuals dealing with both mental health and substance use challenges. The array of comprehensive treatment options available ensures that all clients, regardless of gender, receive the support they need on their path to recovery.

Center for Behavioral Health LLC

Center for Behavioral Health LLC, located in Bowling Green, KY, specializes in outpatient detox and treatment programs for adults and young adults facing substance use challenges. Emphasizing anger management, cognitive behavioral therapy, and motivational incentives, this center offers targeted care for both adult males and females, including those with trauma backgrounds. The facility provides outpatient treatment options using methadone, buprenorphine, or naltrexone for its diverse clientele. Focused on high-quality care, Center for Behavioral Health LLC fosters a nurturing environment for individuals in pursuit of successful addiction recovery.

Centennial Peaks Hospital

Centennial Peaks Hospital located in Louisville, CO, provides an extensive array of rehabilitation services aimed at assisting both adults and children struggling with substance abuse issues alongside accompanying mental health challenges. The center features inpatient detoxification and treatment options, with specific programs developed for active duty military members as well as adult males and females. By utilizing evidence-based methodologies such as cognitive behavioral therapy and motivational interviewing, the center customizes treatment strategies to align with the distinct requirements of each patient. Catering to diverse needs, Centennial Peaks Hospital offers programs for all ages and maintains separate tracks for men and women, promoting a nurturing and inclusive atmosphere for those on the path to recovery.

Center for Behavioral Health LLC

The Center for Behavioral Health LLC, located in Woodbridge, VA, specializes in the treatment of substance use disorders and co-occurring mental health issues for both adults and young adults. This center offers various care options, including intensive outpatient, general outpatient, and programs involving methadone, buprenorphine, or naltrexone. Emphasizing cognitive behavioral therapy, strategies for relapse prevention, and counseling for substance use disorders, the center adopts a personalized treatment approach. Catering to men and women, this facility is recognized for its dedication to providing high-quality care and well-rounded treatment plans aimed at promoting sustainable recovery.

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Centennial Mental Health Center Inc in Julesburg, CO is dedicated to providing specialized outpatient care for individuals grappling with substance use challenges and co-occurring mental health conditions. Their comprehensive approach encompasses services like anger management, cognitive behavioral therapy, and motivational incentives, all designed to address a wide spectrum of client needs. The center distinguishes itself with distinct programs designed for adolescents, adult women, and survivors of sexual abuse, ensuring a highly personalized recovery journey. Catering to adults and seniors across all gender identities, Centennial Mental Health Center Inc is committed to delivering high-quality, individualized treatment plans. Their reliance on evidence-based methodologies and thorough support systems makes them a reliable resource for those pursuing effective recovery.

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Centennial Mental Health Center Inc in Holyoke, CO, delivers targeted outpatient services for adults struggling with addiction and dual diagnoses, as well as for children with significant emotional difficulties. Their therapeutic methods are grounded in proven techniques like anger management, cognitive behavioral therapy, and motivational incentives. The center excels in providing personalized treatment plans, with specific programs designed for teens, women, and survivors of sexual abuse, guaranteeing a customized recovery journey. Catering to adults and seniors of all genders, Centennial Mental Health Center Inc is dedicated to providing excellent care and thorough assistance to individuals confronting substance abuse and mental health concerns.

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The Center for Alcohol and Drug Treatment in Duluth, MN, provides extensive detox services for adults and young adults. Their residential detoxification and round-the-clock care cater to men, women, and seniors. Employing proven methods like CBT, the Matrix Model, and motivational interviewing, they customize treatment plans. The facility offers targeted programs for different demographics, ensuring a personalized and successful recovery path. Patients receive excellent care and encouragement at this respected treatment center.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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