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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Casa Esperanza Inc

Casa Esperanza Inc, situated in Roxbury, MA, provides an extensive array of therapeutic programs aimed at those facing substance use challenges alongside mental health issues. The center offers various outpatient services, including intensive outpatient care and partial hospitalization. It focuses on 12-step support, anger management techniques, and short intervention strategies. Additionally, there are specialized programs designed for active military personnel, as well as adults of all genders, including men and women. Individuals seeking assistance can anticipate receiving top-notch care and encouragement as they navigate their recovery process at this establishment.

Casa Esperanza Inc

Situated in Roxbury, MA, Casa Esperanza Inc delivers extensive treatment for substance use issues and transitional living arrangements specifically for adult women. The center is adept at addressing simultaneous substance use challenges and significant mental health issues in adults, as well as emotional difficulties encountered by children. Emphasizing long-term residential support, Casa Esperanza Inc utilizes a range of evidence-based practices, including 12-step programs and anger management strategies. The center is committed to providing high-quality, gender-sensitive care for its female clientele. It also features specialized programs for active military members, individuals who have experienced intimate partner violence, and those in need of domestic violence assistance. Catering to adults, seniors, and young adults, this facility is focused on promoting enduring recovery through customized treatment strategies.

Casa Esperanza Inc

Casa Esperanza Inc, situated in Boston, MA, specializes in providing targeted substance use recovery services for adult males. This center features intensive hospital inpatient care, round-the-clock medical support, and extended residential treatment options. Their treatment methods encompass 12-step programs, techniques for managing anger, and short-term intervention strategies. Casa Esperanza Inc also supports individuals who have gone through intimate partner violence, domestic abuse, and sexual trauma. Catering to adults, seniors, and young adults alike, the center prioritizes delivering high-quality care within a nurturing and safe atmosphere. If you or someone you know is in search of thorough addiction recovery options focused on personalized support, Casa Esperanza Inc could be an ideal choice.

Casa Palmera
Del Mar, CA

Casa Palmera, situated in Del Mar, California, delivers a wide array of rehabilitation services for those in need of detoxification and recovery from substance use. The center features options including residential detox, round-the-clock care, and short-term residential programs, fostering a nurturing atmosphere conducive to healing. Employing a variety of methodologies such as 12-step support, anger management techniques, and brief interventions, Casa Palmera addresses the unique requirements of each individual. There are specialized programs tailored for active duty military personnel, those experiencing dual diagnoses, and members of the LGBTQ community. Committed to assisting adults and young adults of all genders, Casa Palmera is focused on offering exceptional care and support throughout the recovery journey.

Casa Recovery
San Juan Capistrano, CA

Located in San Juan Capistrano, CA, Casa Recovery offers comprehensive rehabilitation services for adults and young adults struggling with substance use disorders and co-occurring mental health conditions. The facility provides intensive outpatient treatment, outpatient day treatment, and partial hospitalization programs. Casa Recovery specializes in 12-step facilitation, anger management, and brief intervention approaches. Unique programs cater to clients who have experienced sexual abuse, trauma, and those with co-occurring mental health and substance use disorders. With a focus on individualized care, Casa Recovery serves both male and female clients, ensuring a supportive environment for all seeking recovery.

Casa Serena
Santa Barbara, CA

In Santa Barbara, California, you'll find Casa Serena, a leading treatment facility dedicated to offering extended residential care for women of all ages. They excel in managing withdrawal symptoms and treating addiction through proven methods like 12-step support, strategies for managing anger, and brief counseling. Casa Serena is particularly recognized for its tailored programs catering to adult women, survivors of intimate partner violence, domestic abuse, and sexual trauma. Their commitment to exceptional care ensures a secure and nurturing setting for everyone seeking to reclaim their lives.

Casa Washington Heights

Casa Washington Heights, situated in New York, NY, offers a wide array of outpatient treatment services for both adults and young adults dealing with substance use issues. The center excels in addressing co-occurring substance use disorders alongside severe mental health conditions, including emotional challenges faced by children. It employs a variety of therapeutic techniques such as anger management, cognitive behavioral therapy, and motivational interviewing to provide customized care. Casa Washington Heights features specialized programs designed for adult men and women, including support for those affected by intimate partner violence, ensuring that every client receives personalized attention. Their outpatient options include methadone/buprenorphine or naltrexone treatments, as well as standard outpatient services for both males and females, prioritizing high-quality care and assistance for individuals on their path to recovery.

Catalyst
Lawton, OK

Catalyst, situated in Lawton, OK, is a premier facility dedicated to comprehensive recovery from addiction and co-occurring psychological conditions for individuals of all ages. They provide a spectrum of therapeutic options, including intensive outpatient, extended residential stays, and standard outpatient services, all designed to offer personalized support. The center employs distinct therapeutic methods such as 12-step integration, emotional regulation strategies, and concise intervention models. A notable aspect of Catalyst is its specialization in providing separate, tailored treatment tracks for adult men and women, as well as young adults, underscoring their dedication to effective, individualized care.

Catalyst Clinic
Boston, MA

At Catalyst Clinic in Boston, MA, we provide thorough substance use treatment designed for adults, seniors, and younger individuals. Our services encompass various outpatient options, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, standard outpatient care, brief counseling, cognitive behavioral therapy, and motivational strategies like contingency management. We have particular expertise in programs crafted for adolescents and young adults. Dedicated to high-quality care, Catalyst Clinic supports both men and women in their journey toward recovery, offering personalized addiction treatment in a nurturing setting.

Carter Clinic
Raleigh, NC

Carter Clinic, located in Raleigh, NC, specializes in outpatient care for adults dealing with substance use issues and coexisting mental health conditions, as well as providing support for children facing emotional challenges. The center offers a variety of services, including outpatient methadone and buprenorphine therapy, cognitive behavioral therapy, counseling for substance use disorders, and teletherapy options. Carter Clinic is designed to meet the needs of a wide range of clients, including active duty military members, adolescents, and men. This inclusive facility accepts individuals of all genders and prioritizes evidence-based practices along with personalized treatment plans, ensuring a high standard of care for those on their journey to recovery from addiction and mental health difficulties.

Carter Clinic
Laurinburg, NC

Situated in Laurinburg, NC, the Carter Clinic provides a wide range of outpatient rehabilitation services aimed at adults and children facing challenges related to substance use disorders and accompanying mental health problems. The center features targeted treatment plans for active military members, teenagers, and adult males. Employing proven methods such as cognitive behavioral therapy and counseling for substance abuse, the facility also includes telemedicine options to facilitate remote therapy sessions. Committed to personalized care, the Carter Clinic accommodates both men and women, focusing on customized recovery strategies for every patient.

Catalyst Health Solutions

Catalyst Health Solutions, situated in Johnson City, TN, delivers extensive outpatient care for those needing detoxification, addiction treatment, and support for simultaneous mental health concerns. The center features distinct programs for adult men, adult women, and individuals with trauma histories. Therapeutic methods employed include 12-step facilitation, anger management training, and short-term interventions. Emphasizing outpatient detoxification and medication-assisted treatment (methadone, buprenorphine, or naltrexone), Catalyst Health Solutions serves both adults and young people, offering personalized care irrespective of gender. Patients can anticipate high-standard treatment and customized assistance at this establishment.

Cascade Community Healthcare

Cascade Community Healthcare, located in Chehalis, WA, delivers extensive addiction treatment options for individuals of all ages. Their expertise encompasses detox, substance abuse intervention, and the management of dual diagnoses. They offer robust intensive outpatient and standard outpatient care, which includes supervised detox. Employing strategies such as brief intervention, cognitive behavioral therapy, and community reinforcement, Cascade Community Healthcare is equipped to assist those facing both chronic pain and addiction. The center is open to all genders, providing personalized support. Clients can expect effective, research-backed treatments aimed at fostering enduring recovery.

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Smithfield, NC

Situated in Smithfield, NC, the Carter Clinic delivers extensive outpatient treatment for individuals facing substance use issues, including adults and children who also have concurrent mental health challenges. This center features a variety of specialized programs that serve active duty military members, teens, and adult males. Emphasizing cognitive behavioral therapy and counseling for substance use disorders, the clinic also offers telehealth services to enhance accessibility. Aiming to accommodate both men and women, the facility develops personalized treatment plans for every client. The Carter Clinic remains committed to offering top-notch, evidence-driven care to aid individuals in their recovery process.

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Lumberton, NC

Carter Clinic, situated in Lumberton, NC, delivers extensive outpatient rehabilitation services aimed at those facing challenges with substance use disorders, along with co-existing mental health issues. This facility features targeted treatment options for adults grappling with significant mental health concerns, as well as for children experiencing serious emotional difficulties. Employing research-supported techniques like cognitive behavioral therapy and counseling for substance use disorders, Carter Clinic also incorporates telehealth services for greater accessibility. The center has customized programs designed for active duty military, adolescents, and adult males, thus serving a wide variety of individuals. With a focus on both adults and children, Carter Clinic prioritizes individualized treatment strategies for every client, promoting a nurturing atmosphere conducive to recovery.

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Fayetteville, NC

At its Fayetteville, NC location, Carter Clinic specializes in outpatient care for adults struggling with substance use and co-occurring serious mental health issues, as well as for children experiencing serious emotional disturbances. The center employs a range of therapeutic approaches, including cognitive behavioral therapy, substance use disorder counseling, and virtual therapy services. Dedicated programs are available for active duty military personnel, adolescents, and adult men. Treatment modalities include outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Carter Clinic is equipped to assist both male and female individuals of all ages, prioritizing personalized and high-quality care.

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Casa de Consejeria y Salud Integral, situated in Philadelphia, PA, offers thorough addiction recovery services via adaptable outpatient programs designed for each person's unique situation. Employing proven therapeutic methods like brief intervention, cognitive behavioral therapy, and contingency management, the facility delivers dedicated support for adults, young people, and teenagers, irrespective of gender. By emphasizing customized recovery strategies, Casa de Consejeria y Salud Integral guarantees high-quality treatment through its outpatient, medication-assisted treatment (methadone/buprenorphine or naltrexone), and standard outpatient options. Discover supportive and successful recovery from addiction at this establishment.

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Casa de Consejeria y Salud Integral, situated in Philadelphia, PA, delivers extensive outpatient services for individuals struggling with substance use disorders. This center's expertise lies in areas such as anger management, brief interventions, and cognitive behavioral therapy. They provide customized treatment plans designed for adult men, adult women, and individuals involved with the criminal justice system. Open to adults and young adults across all gender identities, Casa de Consejeria y Salud Integral fosters a nurturing space for those pursuing freedom from addiction. Their commitment to high-quality, evidence-based care establishes them as a leading option for those beginning their recovery journey.

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Casa La Providencia Inc, located in San Juan, PR, specializes in extensive residential treatment for substance use and transitional housing specifically designed for women. This center ensures round-the-clock support with tailored programs aimed at empowering adult women on their recovery journey. By implementing methods such as 12-step support, anger management, and short-term interventions, the facility prioritizes personalized care to meet the distinct needs of each individual. Committed to excellence and empathy, this center welcomes women of all ages, providing a secure environment dedicated to fostering sobriety and personal strength.

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The Cass County Health Department, situated in Beardstown, IL, delivers outpatient services for individuals of all ages struggling with substance use disorders. This center excels in addressing dual diagnoses, specifically co-occurring substance use and severe mental health conditions in adults, and serious emotional disturbances in children. Their treatment modalities encompass anger management, brief intervention strategies, and cognitive behavioral therapy, among others. Designed for both men and women, the program emphasizes a personalized approach to recovery. The Cass County Health Department also offers outpatient medication-assisted treatment options, including methadone, buprenorphine, or naltrexone, alongside general outpatient care, demonstrating a dedication to thorough and effective rehabilitation for its clients.

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Casteele Williams and Associates, located in Tacoma, WA, stands as a leading facility dedicated to providing robust outpatient rehabilitation services. Their focus encompasses the complexities of substance use disorders, co-occurring severe mental health conditions, and significant emotional distress. The center excels in approaches like 12-step facilitation, anger management techniques, and brief intervention strategies, offering complete care for individuals across the age spectrum. They offer specific programs for active military personnel, teenagers, adult men, and services catering to all genders. Casteele Williams and Associates fosters a nurturing atmosphere conducive to healing. They extend their high-standard, research-backed treatments to adults and older adults, aiding them in their journey toward sustained sobriety and enhanced mental well-being.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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