NWVCIL Logo
Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

Need Help Finding the Right Treatment Center?

Speak with a compassionate specialist now - 100% free & confidential

Call +1 (833) 244-3031
Available 24/7
All 50 States
Filters:

Showing 21 of 6655 results

Catholic Charities
Hartford, CT

Catholic Charities in Hartford, CT, delivers a full spectrum of substance abuse recovery services for adults managing co-occurring severe mental health challenges and children with significant emotional difficulties. The center employs evidence-based methods like anger management, brief intervention, and cognitive behavioral therapy within its intensive outpatient, outpatient, and standard outpatient programs. Tailored programs are available for teens, adult males, and adult females, addressing the needs of various age demographics and genders. Patients receive personalized, superior care, establishing Catholic Charities as a dependable resource for effective and empathetic recovery support.

Catholic Charities/Rockville Centre

Situated in Hampton Bays, NY, Catholic Charities/Rockville Centre specializes in comprehensive treatment for adults and young adults dealing with substance use issues, particularly those with co-occurring serious mental health conditions or emotional challenges. The center offers outpatient services, including treatments with methadone, buprenorphine, or naltrexone, along with standard outpatient care. Emphasizing techniques such as 12-step facilitation, brief interventions, and cognitive behavioral therapy, this facility serves active duty military members as well as adult men and women. Catholic Charities/Rockville Centre provides customized programs for both genders, ensuring high-quality support for individuals on their path to recovery.

Catholic Community Services

Catholic Community Services located in Seattle, WA provides outpatient treatment for substance use disorders in adults, including those who may also experience significant mental health challenges or emotional issues. This center offers a variety of treatment options, such as outpatient care utilizing methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Emphasizing personalized care, the facility employs evidence-based methods like cognitive behavioral therapy, motivational interviewing, and brief interventions. Customized programs are available for both adults and young adults, accommodating the needs of all genders. For individuals in search of effective addiction treatment that prioritizes individualized support, this center could be an excellent choice.

Cazenovia Manor
Buffalo, NY

Cazenovia Manor, located in Buffalo, NY, is a premier rehabilitation facility dedicated to providing long-term residential treatment for adult men dealing with substance use issues. The center delivers extensive support for individuals who also face mental health challenges concurrently. By implementing proven strategies such as anger management, cognitive behavioral therapy, and motivational incentives, the program serves diverse age groups, including adults, seniors, and young adults in pursuit of recovery. Cazenovia Manor is distinguished by its commitment to addressing both substance use problems and significant mental health disorders, fostering an environment conducive to comprehensive healing. Renowned for its exemplary care and tailored programs, this center serves as a guiding light for those embarking on their path to sobriety.

Cedar Mountain Center at

Situated in Cody, WY, Cedar Mountain Center offers an extensive range of addiction recovery services for both adults and young adults. With a focus on detoxification, treatment for substance use disorders, and addressing co-occurring mental health issues, the center provides round-the-clock hospital inpatient care. Utilizing evidence-driven methods such as cognitive behavioral therapy and 12-step support, clients benefit from care that is customized to meet their specific needs. The center also features specialized programs designed for individuals facing dual diagnoses. Committed to delivering high-quality and tailored treatment, Cedar Mountain Center fosters a nurturing atmosphere for all clients pursuing recovery from addiction and co-occurring conditions.

Catholic Charities of Miami

Catholic Charities of Miami, situated in Miami, FL, provides extensive addiction recovery services for adults and adolescents. This center excels in addressing dual diagnoses, treating individuals with both substance abuse and severe mental health conditions, alongside children experiencing significant emotional challenges. Offering extended residential stays, daily outpatient services, and medication-assisted treatment including methadone, buprenorphine, or naltrexone, the facility tailors each recovery journey with methods like 12-step encouragement, emotional regulation training, and short-term counseling. Special therapeutic offerings are available for those with trauma histories and co-occurring conditions. Emphasizing superior support, Catholic Charities of Miami serves both men and women in pursuit of successful recovery.

Catholic Charities Family and Comm

Situated in Rochester, NY, Catholic Charities Family and Comm delivers an extensive array of addiction treatment services. The center features intensive outpatient programs, standard outpatient services, and options for methadone, buprenorphine, or naltrexone therapy. Emphasizing strategies like anger management, brief interventions, and cognitive behavioral therapy, this facility is designed for adult males and females, including those who have faced intimate partner or domestic violence. Catering to both adults and young adults, this center prioritizes personalized care and assistance for individuals striving to break free from addiction.

Catholic Charities Family and Comm

Nestled in Rochester, NY, Catholic Charities Family and Comm is a dedicated facility providing targeted substance use interventions for adults facing concurrent serious mental health conditions, as well as for children with emotional challenges. Their services encompass intensive outpatient, standard outpatient, and medication-assisted treatment options including methadone, buprenorphine, or naltrexone. Employing therapeutic modalities such as anger management, brief intervention strategies, and cognitive behavioral therapy, the center supports adult men and women, including survivors of intimate partner violence. Catering to a broad age range, from adolescents to seniors, and offering gender-specific programming, Catholic Charities Family and Comm is committed to delivering holistic care that prioritizes individual recovery journeys and optimal treatment results.

Catholic Charities
Leominster, MA

Situated in Leominster, MA, Catholic Charities provides extended residential care aimed at addressing substance use issues, transitional living, and assistance for those dealing with concurrent substance use and significant mental health challenges. The center implements 12-step principles, anger management techniques, and cognitive behavioral strategies to deliver tailored services primarily for adult women who have faced intimate partner violence, domestic violence, or sexual assault. Emphasizing high-quality support, the facility serves adults, seniors, and young adults within a secure and nurturing space. Geared exclusively towards female participants, this initiative fosters a thorough pathway to recovery and emotional restoration.

Catholic Charities
Portland, ME

Catholic Charities, located in Portland, ME, presents a thorough array of substance use rehabilitation services aimed at both adults and younger individuals experiencing concurrent mental health issues. This center offers intensive outpatient and standard outpatient programs, which feature treatment alternatives such as methadone/buprenorphine and naltrexone. Emphasizing 12-step methodologies, anger management techniques, and brief intervention strategies, the facility customizes its treatment approaches to align with the unique needs of each client. Specialized programs are available for adult men and women, as well as those who have faced trauma. By catering to both male and female clients, Catholic Charities commits to delivering exceptional care in a nurturing and understanding atmosphere for individuals pursuing recovery.

Catholic Charities Neighborhood Servs

Situated in Brooklyn, NY, Catholic Charities Neighborhood Servs delivers a wide array of substance abuse treatment programs, with a particular emphasis on addressing co-occurring substance use disorders and severe mental health issues among adults, as well as emotional challenges in children. The facility offers various levels of care, including intensive outpatient, outpatient, and medication-assisted treatment featuring methadone, buprenorphine, or naltrexone. Committed to approaches like 12-step facilitation, anger management, and brief interventions, the center serves adolescents and adult men and women alike. Catering to individuals of all genders, the center prioritizes personalized care to meet diverse needs effectively.

Catholic Charities of Utica/Rome

Catholic Charities of Utica/Rome, situated in Utica, NY, provides extended residential care for adult women battling substance use disorders within a nurturing atmosphere. This establishment offers interim lodging, structured recovery housing, and sober living arrangements for individuals managing both mental health and substance dependency issues. The program employs proven therapeutic methods, including techniques for managing anger, cognitive restructuring, and motivational strategies, to adeptly meet each person's unique challenges. Emphasizing support for those with a history of trauma, the center serves adults, older adults, and younger adults in search of all-encompassing support within a women-only environment. Catholic Charities of Utica/Rome is committed to delivering superior rehabilitative services to foster enduring recovery.

Cecil Community Recovery Center LLC

Cecil Community Recovery Center LLC in Elkton, MD provides outpatient addiction treatment for adults and young adults. Their services include specialized programs for methadone, buprenorphine, or naltrexone treatment, as well as general outpatient care. They employ therapeutic methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. This center offers gender-specific treatment and is dedicated to providing high-quality, personalized support for individuals pursuing recovery from substance use disorders.

Catholic Charities of SE Michigan

Catholic Charities of SE Michigan, situated in Lapeer, MI, delivers expert outpatient services designed for individuals of all ages struggling with substance abuse and related mental health challenges. Their approach is personalized, incorporating methods like 12-step support, anger management techniques, and brief intervention strategies. The center is equipped to support adolescents, adult men, and women through various treatment options, including outpatient medication-assisted treatment (methadone, buprenorphine, naltrexone) and standard outpatient care, all aimed at fostering lasting recovery.

Placeholder image
Worcester, MA

Catholic Charities, located in Worcester, MA, provides an extended residential program for men struggling with substance abuse in a nurturing atmosphere. This center implements tailored treatment methods, including 12-step programs, anger management strategies, and cognitive behavioral therapy. It features distinct services aimed at adult men, survivors of sexual trauma, and those affected by other traumatic experiences. Additionally, the facility offers transitional housing, halfway houses, and sober living arrangements. Catering to a range of male demographics, from young adults to seniors, Catholic Charities is committed to delivering effective support for those on their path to recovery from addiction. Its diverse range of services and focused programs position it as a key player in the field of rehabilitation.

Placeholder image
Cleveland, OH

Situated in Cleveland, Ohio, Catholic Charities delivers a broad spectrum of rehabilitation services for those battling substance abuse and related mental health issues. The center features intensive outpatient, outpatient, and round-the-clock residential programs, employing proven methods such as 12-step support, anger management, and cognitive behavioral therapy. Catholic Charities specifically addresses the needs of adult men and women, including individuals who have faced sexual trauma, providing tailored care for these populations. Emphasizing quality and personalized treatment, this facility creates an encouraging atmosphere for recovery and personal growth.

Placeholder image

Catholic Charities Maine in Auburn, ME, provides comprehensive long-term residential care for adult men facing substance use disorders and co-occurring severe mental health conditions. This center delivers round-the-clock support through proven methods such as 12-step facilitation and anger management. It features distinct programs tailored for active military members, survivors of domestic abuse, and individuals needing short-term interventions. Serving adult, senior, and young adult males, the facility prioritizes personalized treatment plans and assistance for each client's recovery path. Catholic Charities Maine is committed to delivering excellent rehabilitation services in a secure and supportive setting.

Placeholder image

Situated in Utica, NY, Catholic Charities/Diocese of Syracuse provides high-quality substance abuse treatment in a long-term residential framework for adult males. This center delivers targeted care for individuals dealing with both mental health and substance abuse challenges, utilizing methods such as anger management, cognitive-behavioral therapy, and motivational techniques. Programs are customized for clients with a history of trauma. The center also features transitional housing and sober living options. Aimed at adult, senior, and younger adult males, this facility creates a nurturing atmosphere for individuals pursuing extensive rehabilitation support.

Placeholder image

Situated in Marquette, MI, Catholic Social Services of the UP delivers a wide range of services for addressing substance use disorders among adults and young adults. The center offers outpatient support, along with treatments involving methadone, buprenorphine, or naltrexone, in addition to standard outpatient care. Emphasizing approaches such as 12-step programs, brief interventions, and cognitive behavioral therapy, treatment plans are customized to meet the unique needs of each client. There are specialized programs available for active duty military personnel as well as separate services for adult men and women. Catering to both genders, the center is committed to providing exceptional care within a nurturing atmosphere. Catholic Social Services of the UP focuses on empowering individuals to conquer addiction and attain sustainable recovery.

Placeholder image

Catholic Social Services of the UP in Escanaba, MI, delivers extensive addiction recovery services to adults and young adults. Their offerings include outpatient treatment with methadone, buprenorphine, or naltrexone, alongside general outpatient care. They also utilize therapeutic interventions such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. The center features specialized programs designed for active military personnel, adult men, and adult women, guaranteeing personalized support for varied requirements. This facility, catering to both male and female individuals, is dedicated to providing excellent care and encouragement for those pursuing freedom from addiction. Catholic Social Services of the UP is distinguished by its focused approaches and unwavering dedication to assisting individuals in attaining sustained recovery.

Placeholder image

Cayuga Addiction Recovery Services, located in Trumansburg, NY, provides extensive live-in treatment for adult males struggling with addiction and concurrent severe mental health issues. This establishment is particularly skilled in creating individualized plans for individuals with histories of intimate partner violence, domestic abuse, and sexual assault. Employing 12-step encouragement, emotional regulation strategies, and concise intervention methods, the center delivers holistic support to adults, older individuals, and younger adults. The round-the-clock residential atmosphere offers a nurturing space for men pursuing sobriety. Cayuga Addiction Recovery Services is dedicated to offering excellent services with a unique emphasis on tackling trauma and co-occurring conditions with empathy and efficacy.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

Naltrexone resources:

Find Naltrexone (Vivitrol) by State

Browse naltrexone (vivitrol) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)