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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Center for Comp Health Practice

The Center for Comp Health Practice, located in New York, NY, provides a diverse array of outpatient programs aimed at treating substance use disorders. With a focus on individuals facing both substance use and significant mental health challenges, the center delivers targeted support for both adults and young adults. Emphasizing techniques such as cognitive behavioral therapy, brief interventions, and anger management, treatment plans are customized to meet the specific requirements of each client. The center also features unique programs specifically designed for adult men and women, as well as those who have dealt with domestic or intimate partner violence. Offering outpatient options with methadone, buprenorphine, or naltrexone, the facility is committed to delivering high-quality care for clients in their recovery journey.

Center for Family Services

Situated in Camden, NJ, the Center for Family Services delivers extensive treatment options for substance use disorders aimed at both adults and young adults. The facility offers a range of services, including intensive outpatient programs, standard outpatient care, and outpatient options featuring methadone, buprenorphine, or naltrexone. Emphasizing methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, the center customizes its approach to meet the specific needs of each patient. Special initiatives are available for adult women, individuals who have faced trauma, and those dealing with simultaneous mental health and substance use challenges. Catering to both men and women, the center provides excellent support and care for those on their journey to recovery from addiction.

Center for Creative Values Inc

Center for Creative Values Inc, situated in Towson, MD, provides a wide array of treatment solutions for those dealing with substance use issues and related mental health disorders. This center features intensive outpatient programs, day treatment, and partial hospitalization, employing methods like cognitive behavioral therapy, anger management, and brief interventions. The facility has tailored services for active duty military members, as well as programs for adult men and women, ensuring it meets the needs of a varied clientele. Committed to serving adults and seniors of any gender, the center prioritizes high-quality, individualized care to address each person's specific requirements.

Center for Behavioral Health Iowa

Situated in Davenport, IA, the Center for Behavioral Health Iowa delivers outpatient care for substance use issues, emphasizing treatments like methadone, buprenorphine, or naltrexone. The facility also offers standard outpatient services along with diverse strategies such as anger management, brief interventions, and cognitive behavioral therapy. This center features dedicated programs for adult males and females, accommodating both adults and younger adults. With a focus on high-quality care and a variety of customized services, the Center for Behavioral Health Iowa stands out as a supportive option for those pursuing effective and individualized treatment for addiction in the Davenport region.

Center for Behavioral Health
North Charleston, SC

Situated in North Charleston, SC, the Center for Behavioral Health provides an extensive array of outpatient services focused on detoxification and treatment for substance use disorders. The offerings encompass outpatient detox as well as treatment with methadone, buprenorphine, or naltrexone. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, this center supports active duty military members, adult males, and adult females. Catering to adults and young adults of all genders, the Center for Behavioral Health delivers personalized care designed to meet the specific requirements of individuals, guaranteeing effective treatment for those on the path to addiction recovery.

Center for Family Services

Situated in Voorhees, NJ, the Center for Family Services specializes in providing targeted substance abuse treatment programs for both adults and young adults. The facility features intensive outpatient programs, outpatient services, and options for outpatient treatment with methadone, buprenorphine, or naltrexone. Emphasizing personalized care, the center employs various strategies, including 12-step facilitation, anger management, and brief intervention. To address the distinct needs of each individual, the Center for Family Services offers treatments tailored specifically for men and women. For those in search of thorough addiction support with a customized approach, this center is committed to delivering exceptional care to aid in your recovery process.

Center for Behavioral Health

The Center for Behavioral Health, situated in Las Vegas, NV, provides focused outpatient care for adults struggling with addiction and concurrent mental health challenges, as well as children experiencing emotional difficulties. Their services employ a variety of proven methods, such as techniques for managing anger, cognitive behavioral therapy, and motivational incentives. The center caters to specific needs with customized plans for adult men and women, those affected by domestic violence or intimate partner violence, and survivors of such abuse. With a commitment to offering top-tier care in a nurturing setting, the center supports adults and young adults across the gender spectrum. For extensive outpatient support, including medication-assisted treatment like methadone or buprenorphine, the Center for Behavioral Health stands as a reliable source for effective and empathetic healing.

Center for Family Services

Situated in Williamstown, NJ, the Center for Family Services delivers a wide range of substance use treatment options, including intensive outpatient, outpatient, and medication-assisted therapies. This center focuses on 12-step facilitation, anger management, and short interventions to effectively tackle addiction issues. With specialized programs designed for adult males and females, it also accommodates young adults from both sexes. The Center for Family Services fosters a nurturing and welcoming atmosphere for those in search of high-quality care and individualized treatment for substance use challenges. Whether you require outpatient support or medication-assisted solutions, this facility is committed to guiding individuals toward sustainable recovery.

Center for Behavioral Health Idaho Inc

Situated in Meridian, ID, the Center for Behavioral Health Idaho Inc provides outpatient detox and treatment services for substance use aimed at both adults and young adults. This center offers tailored care for adult men, women, and those who are pregnant or in the postpartum phase. Employing methods such as brief intervention, cognitive behavioral therapy, and community reinforcement with vouchers, it delivers high-quality, gender-sensitive treatment. Committed to personalized care, this facility serves male and female clients in need of effective addiction support within a nurturing atmosphere.

Center for Behavioral Health Idaho Inc

The Center for Behavioral Health Idaho Inc, situated in Boise, ID, provides outpatient services for detoxification and addiction recovery. This center is dedicated to assisting adult men, adult women, pregnant or postpartum women, and young adults. Their treatment methods encompass brief intervention strategies, cognitive behavioral therapy, and a community reinforcement approach supplemented with vouchers. The facility emphasizes delivering high-quality care and offers distinct programs tailored for both male and female patients. For those in search of thorough addiction treatment within a supportive outpatient environment, this center offers personalized programs designed to address individual requirements.

Center for Behavioral Health
North Las Vegas, NV

Based in North Las Vegas, NV, the Center for Behavioral Health specializes in thorough outpatient detox and treatment programs for substance use. The center employs proven methodologies, including cognitive behavioral therapy and anger management, to offer tailored support to adult men, women, and young adults dealing with simultaneous mental health and substance use issues. Emphasizing personalized treatment strategies and motivational incentives, the facility fosters a nurturing atmosphere conducive to recovery. This program serves clients of all genders, providing exceptional care aimed at helping individuals attain sustainable sobriety and enhanced mental health.

Center for Behavioral Health
North Las Vegas, NV

The Center for Behavioral Health in North Las Vegas, NV, provides expert outpatient therapy for addiction and related mental health conditions. They have diverse services for adults and young adults, such as anger management, CBT, and motivational incentives. The center also features special programs for men, women, and survivors of domestic abuse. Committed to excellent, personalized care, the Center for Behavioral Health guides clients toward lasting recovery. They offer complete support for various needs, from standard outpatient services to methadone/buprenorphine treatment.

Center for Behavioral Health

The Center for Behavioral Health in Reno, NV, provides outpatient support for adults struggling with addiction, including individuals also managing significant mental health conditions. The center excels in addressing dual diagnoses with targeted strategies like anger management, brief interventions, and cognitive behavioral therapy. Customized treatment plans are developed for adult men, adult women, and young adults facing challenges with both substance use and mental well-being. Committed to high standards of care, the facility offers medication-assisted treatment with methadone, buprenorphine, or naltrexone, integrated with their general outpatient services. Clients receive thorough assistance within a professional and supportive setting.

Center for Behavioral Health Inc

Situated in Tucson, AZ, the Center for Behavioral Health Inc delivers targeted programs for the treatment of substance use disorders aimed at both adults and young adults. This center specializes in outpatient services, which include methadone/buprenorphine or naltrexone therapy, regular outpatient care, and a variety of evidence-backed interventions such as cognitive behavioral therapy, anger management, and motivational incentives/contingency management. Emphasizing personalized care, the center provides specialized programs for adult males, adult females, and individuals dealing with both mental health and substance use challenges. The array of comprehensive treatment options available ensures that all clients, regardless of gender, receive the support they need on their path to recovery.

Center for Behavioral Health LLC

Center for Behavioral Health LLC, located in Bowling Green, KY, specializes in outpatient detox and treatment programs for adults and young adults facing substance use challenges. Emphasizing anger management, cognitive behavioral therapy, and motivational incentives, this center offers targeted care for both adult males and females, including those with trauma backgrounds. The facility provides outpatient treatment options using methadone, buprenorphine, or naltrexone for its diverse clientele. Focused on high-quality care, Center for Behavioral Health LLC fosters a nurturing environment for individuals in pursuit of successful addiction recovery.

Center for Behavioral Health LLC

The Center for Behavioral Health LLC, located in Woodbridge, VA, specializes in the treatment of substance use disorders and co-occurring mental health issues for both adults and young adults. This center offers various care options, including intensive outpatient, general outpatient, and programs involving methadone, buprenorphine, or naltrexone. Emphasizing cognitive behavioral therapy, strategies for relapse prevention, and counseling for substance use disorders, the center adopts a personalized treatment approach. Catering to men and women, this facility is recognized for its dedication to providing high-quality care and well-rounded treatment plans aimed at promoting sustainable recovery.

Center for Emotional Care

Situated in Salem, VA, the Center for Emotional Care delivers outpatient services for substance use treatment targeting both adults and children who are facing concurrent mental health challenges. This center offers personalized care via 12-step facilitation methods and specifically crafted programs for individuals with dual diagnoses. Emphasizing outpatient options such as methadone, buprenorphine, or naltrexone treatments, it serves adults and seniors of all genders. The Center for Emotional Care distinguishes itself through its holistic strategy in tackling substance use disorders in conjunction with significant emotional issues. Engage in quality support within a nurturing atmosphere that fosters healing and recovery.

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The Center for Community Alternatives Inc, located in Brooklyn, NY, provides various specialized programs aimed at addressing substance abuse and related mental health concerns for both adults and children. Their offerings include intensive outpatient services, standard outpatient treatment, as well as methadone, buprenorphine, or naltrexone therapies. The center utilizes evidence-based methods like anger management, brief interventions, and cognitive behavioral therapy to meet the unique needs of each client. They have distinct programs designed for individuals who have faced intimate partner violence, domestic violence, or who are navigating the criminal justice system. Catering to both men and women, this facility emphasizes comprehensive care that prioritizes holistic recovery and sustainable outcomes.

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The Center for Family Services, located in Washington, NJ, specializes in outpatient treatment for adults dealing with substance abuse and significant mental health disorders, as well as children facing severe emotional challenges. Utilizing methods grounded in research such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse, the center has tailored programs to assist adolescents and individuals who have encountered intimate partner violence, domestic abuse, and trauma. This facility caters to all genders among adults and children/adolescents, ensuring personalized care and a supportive atmosphere. Committed to high-quality and holistic services, the Center for Family Services is focused on guiding individuals towards recovery and improved well-being.

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The Center for Family Services in Phillipsburg, NJ, provides extensive substance abuse treatment services for individuals of all ages. The center excels in addressing dual diagnoses, treating co-occurring addiction and mental health conditions in adults, and co-occurring addiction and emotional disorders in young people. Employing therapeutic approaches such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, they offer various levels of care, including intensive outpatient, general outpatient, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. Targeted programs are available for adolescents, adult women, and survivors of domestic or intimate partner violence. This facility is committed to delivering personalized, evidence-informed care to foster sustained recovery for all clients.

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Situated in North Brunswick, NJ, the Center for Great Expectations specializes in offering various treatment options for individuals dealing with substance abuse and concurrent mental health issues, catering to both adults and children. The center features an array of services, including intensive outpatient programs, general outpatient care, and medication-assisted treatments with methadone, buprenorphine, or naltrexone. By employing strategies such as anger management, cognitive behavioral therapy, and motivational interviewing, the center customizes its approach to address the unique needs of each client. Additionally, it provides specific programs for adult men and women, as well as for those who have faced intimate partner violence, fostering a nurturing environment for all participants. Committed to delivering high-quality support, the Center for Great Expectations serves individuals of all genders on their journey to recovery.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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