Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,711 treatment centers offering naltrexone (vivitrol) across the United States.
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Nestled in San Jose, CA, Central Valley Clinic delivers a full spectrum of substance abuse recovery services via personalized outpatient plans. They offer medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient care. Their approach incorporates scientifically proven methods such as anger management, cognitive behavioral therapy, and motivational interviewing. The clinic is adept at serving adult men and women, including those affected by intimate partner or domestic violence. Central Valley Clinic is dedicated to providing effective rehabilitation and compassionate support to adults and young adults of all genders.

Central Wyoming Counseling Center in Casper, WY, provides extensive support for individuals struggling with substance abuse and offers tailored services for children and adults facing concurrent mental health challenges. The center delivers various treatment modalities, including intensive outpatient, extended residential stays, and flexible outpatient options, all adapted to each person's unique requirements. Employing proven therapeutic methods such as cognitive behavioral therapy and anger management, Central Wyoming Counseling Center also features distinct programs for active military personnel, teenagers, and adult men. The facility is dedicated to serving adults and seniors across all gender identities, prioritizing excellent care aimed at fostering lasting recovery and overall wellness.

Chalmers P Wylie VA ACC located in Columbus, OH, provides an extensive variety of rehabilitation services aimed at adults and young adults who are struggling with substance abuse along with co-existing mental health issues. Their offerings encompass detoxification, intensive outpatient therapy, and targeted assistance for those affected by intimate partner violence. Emphasizing techniques such as 12-step facilitation, anger management, and brief interventions, this facility delivers customized support for both genders. The center's dedication to high-quality care and a range of treatment modalities position it as an essential asset for individuals in need of effective and compassionate support in overcoming addiction.

Situated in Lexington, KY, Changed Lives Mental Health and Rehabilitation Center provides extensive treatment options for adults dealing with substance use issues alongside major mental health challenges. The facility offers a range of programs including intensive outpatient, outpatient, and standard outpatient services, employing methodologies such as 12-step facilitation, anger management techniques, and brief interventions. Tailored programs are available for adult men and women, as well as children and adolescents, including services for those affected by domestic or intimate partner violence. With a focus on delivering effective care to both genders, this center is committed to supporting individuals on their journey toward sustained recovery and enhanced mental health.

Changed Lives Substance in Lexington, KY provides tailored programs for individuals of all ages struggling with addiction and accompanying mental health conditions. The center utilizes proven therapies, including 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, within intensive outpatient and standard outpatient settings. Services are available for adult men and women, as well as those affected by domestic or intimate partner violence. Changed Lives Substance is dedicated to personalized care for adults, children, and adolescents, assisting both males and females on their journey to recovery and enhanced mental well-being.

Nestled in Kitty Hawk, NC, "Changing Tides" delivers complete addiction recovery care for adults and young adults. The center provides detox, substance abuse therapy, and supportive transitional housing. Tailored programs like intensive outpatient, day treatment, and partial hospitalization are available, incorporating methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. Catering to both men and women, "Changing Tides" emphasizes a personalized, whole-person path to healing, offering excellent support for individuals battling addiction.

Chapa de Indian Health Program Inc, located in Auburn, CA, provides extensive outpatient care for those needing detoxification, help with substance use, and support for co-occurring mental health challenges. They have distinct programs designed for pregnant and postpartum women, addressing the specific requirements of adults and older adults, with gender-sensitive treatment available for men and women. The center employs methods like anger management, brief intervention, and cognitive behavioral therapy to customize treatment plans. Additionally, their outpatient detoxification services and methadone/buprenorphine treatment options improve the ease of access and success of their care, ensuring excellent treatment for everyone requiring it.

Channel Islands Rehab, situated in Oxnard, California, delivers extensive addiction recovery services tailored for both adults and young adults. The center features a hospital-based inpatient detox and treatment program that includes specialized options for active military members, as well as for adult males and females. Treatment methodologies employed here encompass 12-step facilitation, cognitive behavioral therapy, and the Matrix Model. Channel Islands Rehab also supports individuals dealing with both substance use disorders and significant mental health challenges. With a commitment to high-quality care, this facility prioritizes the specific requirements of clients on their journey to overcoming addiction.

Carrollton Springs, located in Plano, TX, provides a wide array of evidence-supported rehabilitation programs for individuals dealing with substance abuse and co-existing mental health issues, targeting both adults and children. The services offered include intensive outpatient programs, outpatient day services, and partial hospitalization. The center focuses on techniques such as brief intervention, cognitive behavioral therapy, and strategies for preventing relapse. Specialized programs are available for active military members, LGBTQ individuals, and those facing dual diagnoses. Catering to a diverse population of adults and young adults, this facility is committed to delivering exceptional care within a nurturing atmosphere. If you're in search of effective and empathetic support for addiction recovery, Carrollton Springs stands out as an exemplary option.

ChangePoint Integrated Health, located in Show Low, AZ, provides a wide range of services for individuals dealing with substance use disorders and co-existing serious mental health challenges in adults, as well as emotional disturbances in children. The facility offers various treatment options, including intensive outpatient programs, outpatient services, and medications such as methadone, buprenorphine, or naltrexone. Utilizing techniques such as anger management, brief interventions, and cognitive behavioral therapy, the center supports adolescents, men, and women. ChangePoint Integrated Health is dedicated to delivering high-quality care to adults and seniors of all genders, focusing on personalized treatment strategies and evidence-based methods to facilitate enduring recovery.

Situated in Plattsburgh, NY, Champlain Valley Family Center delivers a wide array of outpatient programs for substance use treatment. This center is dedicated to addressing co-occurring substance use disorders alongside significant mental health challenges in adults, in addition to supporting children with emotional issues. Emphasizing approaches such as cognitive behavioral therapy, anger management, and short-term interventions, the center offers personalized treatment plans for adult men and women, teenagers, and older adults. By focusing on outpatient therapies involving methadone, buprenorphine, or naltrexone, this facility prioritizes providing effective care for those on the road to recovery. It welcomes a diverse clientele, fostering a nurturing atmosphere for everyone in need of rehabilitation assistance.

Champlain Valley Family Center, situated in Schuyler Falls, NY, delivers thorough support for addiction recovery. This facility offers extended residential stays, detox services, and round-the-clock assistance for adults and young adults. Their approach integrates 12-step principles, anger management techniques, and brief intervention strategies, serving both men and women. Dedicated programs are designed for active military members, adult males, and adult females. Champlain Valley Family Center is committed to delivering excellent care and tailored treatment paths to guide individuals toward overcoming substance use challenges.

ChangePoint Integrated Health, located in Winslow, AZ, specializes in holistic treatment for adults facing substance use issues alongside mental health disorders. The facility offers both intensive outpatient and standard outpatient services, featuring treatment alternatives such as methadone, buprenorphine, and naltrexone. Emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy, ChangePoint devises customized treatment strategies to meet the unique needs of each individual. The center also has specialized programs designed for adolescents and distinct groups, including adult men and women. By welcoming adults and seniors of all genders, ChangePoint Integrated Health is committed to delivering excellent care and support to those on their journey to recovery from addiction and mental health struggles.

Changes Springs Dublin, located in Dublin, OH, provides a holistic approach to treating substance use disorders in both adults and children, particularly those facing simultaneous mental health challenges. The center features a range of treatment options, including intensive outpatient programs, outpatient day treatments, and partial hospitalization. It specializes in tailored programs for youths, women, and those with co-occurring conditions, addressing a wide spectrum of needs. By employing methodologies such as 12-step support, anger management, and brief intervention strategies, the facility focuses on personalized care. Accommodating clients of all genders, it emphasizes high-quality treatment to foster sustainable recovery for individuals grappling with addiction and mental health issues.

Located in Angels Camp, CA, Changing Echoes is a dedicated facility providing extensive support for individuals overcoming addiction. They focus on long-term residential stays, safe detoxification within a residential setting, and round-the-clock residential care for both adults and younger adults. Their therapeutic methods include 12-step integration, anger management techniques, and brief intervention strategies to create individualized recovery plans. Changing Echoes is particularly committed to serving adult men and women, including those who have faced intimate partner or domestic violence, fostering a safe and welcoming atmosphere. Their dedication to customized care and scientifically proven methods positions them as an excellent option for those pursuing successful recovery.

"Changing Lives at Home Mental Health in Baltimore, MD, delivers thorough treatment for substance abuse and concurrent mental health issues for both adults and children. It features specialized programs tailored for active military personnel, teenagers, and adult males. The center offers both intensive outpatient and outpatient care, including options for daytime treatment. By employing proven methods such as 12-step support, anger management, and short interventions, the facility accommodates male and female clients of various ages. Its dedication to high standards of care and personalized treatment strategies makes it a trusted option for individuals pursuing successful rehabilitation."

Centrec Care, located in Saint Louis, MO, delivers a wide range of addiction treatment services for both adults and young adults. The center specializes in detoxification, addressing substance use issues, and providing targeted support for individuals dealing with co-occurring disorders, including serious mental health challenges for adults and emotional issues for children. With a variety of treatment formats such as intensive outpatient, outpatient, and day programs, patients have access to resources like 12-step facilitation, anger management sessions, and brief intervention strategies. Centrec Care serves adult men, women, and active duty military members, offering tailored care aimed at fostering recovery, making it a top option for those in need of effective and empathetic addiction support.

ChangePoint Integrated Health in Snowflake, AZ, provides a wide array of services aimed at treating substance use disorders for both adults and children facing concurrent mental health challenges. Their offerings encompass intensive outpatient programs, standard outpatient treatment, as well as specific options for methadone, buprenorphine, or naltrexone therapies. Emphasizing techniques such as anger management, brief intervention strategies, and cognitive behavioral therapy, this center delivers customized assistance for youths, adult males, and adult females. ChangePoint Integrated Health is committed to delivering exceptional care for individuals of all genders, including seniors, as they navigate their recovery journey.

ChangePoint Integrated Health in Holbrook, AZ, is a premier facility dedicated to adults facing substance use disorders, particularly those with concurrent serious mental health conditions or emotional challenges in youth. They offer robust intensive outpatient and standard outpatient services, which include pharmacotherapy options like methadone and buprenorphine. Their therapeutic approach incorporates proven methods such as anger management, brief interventions, and cognitive behavioral therapy. ChangePoint Integrated Health serves a diverse population, including adolescents, adult men, adult women, and seniors, ensuring gender-inclusive and age-appropriate care. This center is committed to providing exceptional, all-encompassing rehabilitation programs focused on achieving sustained recovery and overall well-being.

ChangePoint Psychiatric Hospital, located in Lakeside, AZ, provides a wide range of rehabilitation services aimed at adults and young adults struggling with addiction and concurrent mental health challenges. The center features targeted programs designed for adult males, adult females, and those who have faced experiences of intimate partner violence. Various treatment methods are utilized, including anger management, brief interventions, and cognitive behavioral therapy. Committed to delivering high-quality care, the facility offers inpatient detoxification along with treatment services, ensuring around-the-clock support. ChangePoint Psychiatric Hospital is dedicated to serving both men and women, offering personalized care plans for each individual on their path to recovery.

Changing Turn Community Healthcare, located in Edgewood, MD, provides extensive care for adults and young adults battling addiction, especially those also dealing with significant mental health or emotional challenges. Their services include intensive outpatient care, standard outpatient services, and day treatment or partial hospitalization programs. The center employs therapeutic techniques such as anger management, brief intervention, and cognitive behavioral therapy, customizing each treatment plan to the client's unique needs. Catering to both men and women, the facility emphasizes gender-specific support throughout the recovery process. Changing Turn Community Healthcare is distinguished by its commitment to delivering excellent, individualized care, aiding individuals on their journey toward lasting recovery.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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