Naltrexone and Vivitrol Treatment Centers
Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.
Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.
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Centerstone of Illinois in Alton, IL, provides dedicated care for individuals struggling with substance use disorders and co-occurring mental health challenges. They offer tailored treatment plans for adults and young people, encompassing intensive outpatient and standard outpatient services. Medication-assisted treatment options, including methadone, buprenorphine, and naltrexone, are available. The center emphasizes therapeutic modalities such as 12-step facilitation, anger management, and brief intervention strategies, with a particular understanding of trauma-informed care. Serving all genders across adult and child/adolescent populations, Centerstone of Illinois is committed to fostering an inclusive and supportive environment for those pursuing sustained sobriety.

Centerstone of Illinois, located in Anna, IL, provides a wide range of addiction recovery services tailored for both adults and young adults. The center features specialized programs designed for active military personnel, as well as separate tracks for adult men and women, ensuring customized support for each group. Treatment modalities available include detox services, intensive outpatient programs, long-term residential care, and various outpatient options. Utilizing evidence-based methods such as 12-step support, anger management strategies, and brief intervention techniques, the facility effectively targets substance use issues. Committed to delivering high-quality care and personalized treatment plans, Centerstone of Illinois strives to facilitate clients' paths to recovery.

Centerstone of Illinois in Carbondale, IL, delivers targeted therapies for individuals of all ages struggling with substance use and co-occurring mental health conditions. The program features intensive and standard outpatient care, encompassing medication-assisted treatment like methadone and buprenorphine. Utilizing methodologies such as 12-step facilitation, anger management techniques, and brief intervention strategies, the center customizes treatment plans to suit each person's unique requirements. They have particular expertise in supporting clients with trauma histories, serving adults, children, and adolescents across the gender spectrum. Centerstone of Illinois is dedicated to providing thorough, excellent rehabilitation services to aid individuals in their path to wellness.

Centerstone of Indiana Inc, located in Lexington, IN, provides extensive residential treatment for individuals facing substance use issues alongside co-occurring mental health challenges, catering to both adults and children. Their offerings include a range of evidence-based methods, such as 12-step programs, anger management techniques, and cognitive behavioral therapy. The center has a special focus on supporting adult women and individuals who have experienced intimate partner violence, domestic abuse, and sexual trauma. By prioritizing personalized care for adult, senior, and young adult females, Centerstone of Indiana Inc is dedicated to guiding clients through their recovery journey with high-quality support.

Centerstone of Indiana Inc, located in Lexington, IN, offers a wide range of substance use treatment and transitional housing options within a long-term residential framework. This center is dedicated to addressing both substance use disorders and significant mental health challenges in adults, as well as emotional disturbances in younger populations. The treatment methods employed include 12-step programs, anger management techniques, and cognitive behavioral therapy. Special emphasis is placed on assisting adult women who have faced challenges such as intimate partner violence, domestic abuse, or sexual trauma. Catering to adults, seniors, and young women, this center prioritizes individualized care and support to facilitate each client's recovery journey.

Centerstone of Indiana Inc in Columbus, IN, delivers thorough care for substance misuse and concurrent serious mental health disorders or emotional disruptions. This center features intensive outpatient, standard outpatient, and medication-assisted treatment programs, including methadone, buprenorphine, or naltrexone. Employing methods such as anger control, brief guidance, and cognitive-behavioral therapy, the facility customizes treatment plans. Specialized services are offered for young people, adult males, and adult females. Catering to adults and older adults of all genders, Centerstone of Indiana Inc is dedicated to providing excellent support for individuals navigating recovery from addiction and mental health issues.

Centerstone of Illinois, located in West Frankfort, IL, provides extensive treatment for adults facing substance use disorders, particularly those with significant mental health challenges, as well as for children dealing with severe emotional issues. The facility offers both intensive outpatient and outpatient programs that include options such as methadone, buprenorphine, or naltrexone therapies. Emphasizing strategies like 12-step support, anger management, and brief interventions, the center addresses the needs of individuals who have undergone trauma. Catering to a diverse population of adults and children/adolescents, Centerstone of Illinois ensures personalized care that meets the specific requirements of each person.

Centerstone of Indiana Inc, located in Seymour, IN, provides outpatient treatment for individuals dealing with substance use issues alongside significant mental health challenges or emotional difficulties. The center offers a range of tailored services, including outpatient treatments with methadone, buprenorphine, or naltrexone, as well as programs focused on anger management, brief interventions, and cognitive behavioral therapy. Catering to both adult men and women, the facility also supports clients who have faced domestic violence or intimate partner violence. With a commitment to high-quality, personalized care, Centerstone of Indiana Inc creates effective programs aimed at assisting adults and seniors in their journey toward recovery and overall well-being.

Centerstone of Indiana Inc in Richmond, IN, delivers focused inpatient care for adult males contending with addiction and accompanying severe mental health issues or emotional difficulties. Employing methods such as 12-step support, emotional regulation techniques, and cognitive restructuring, the facility offers individualized support to those affected by past trauma, domestic abuse, or relationship violence. Serving adults, older adults, and younger adults, this male-exclusive residence provides both brief and round-the-clock accommodation. The center's all-encompassing strategies and distinct services position it as a prime option for individuals requiring effective treatment for multifaceted substance abuse and mental health concerns.

Centerstone of Indiana Inc in Scottsburg, IN provides extensive outpatient services for addiction and dual diagnoses. Their expert care encompasses medication-assisted treatment for opioid use disorder, anger management programs, short-term interventions, and cognitive behavioral therapy. This center serves adult men, adult women, and survivors of domestic or intimate partner abuse. Focusing on adults and seniors, Centerstone delivers individualized, evidence-based treatment in a nurturing setting, guided by skilled professionals.

Centerstone of Illinois, situated in Marion, IL, delivers targeted addiction recovery services for individuals and young people managing concurrent severe mental health challenges. The clinic offers robust outpatient programs, standard outpatient care, and medically supported recovery plans. Emphasizing strategies like 12-step encouragement, emotional regulation skills, and concise therapeutic methods, the center customizes its offerings to suit each person's unique requirements. With expertise in care designed to address past trauma, Centerstone of Illinois supports both male and female patients. The clinic's all-encompassing methodology and commitment to superior support establish it as a crucial provider for those in the Marion vicinity pursuing successful recovery solutions.

Centerstone of Indiana Inc, located in Martinsville, IN, provides outpatient services for individuals dealing with substance use issues and those facing co-occurring mental health conditions in adults or emotional challenges in children. Their offerings include anger management, brief interventions, and cognitive behavioral therapy. The facility also delivers outpatient treatment options involving methadone, buprenorphine, or naltrexone. Catering to a diverse clientele, they have specialized programs for adolescents, adult men, and adult women, serving both male and female adults and seniors. Centerstone of Indiana Inc is dedicated to delivering personalized care and tailored treatment plans to foster recovery and enhance overall well-being.

Centerstone of Indiana Inc, located in Bedford, IN, delivers outpatient services focused on treating substance abuse and concurrent serious mental health disorders in adults, along with significant emotional issues in children. The center is proficient in anger management, short-term interventions, and cognitive behavioral therapy, offering personalized treatment for adult men and women, seniors, and those who have faced intimate partner or domestic violence. With offerings catered to both genders, this facility is committed to providing extensive assistance for a wide variety of individuals in need of effective rehabilitation support.

Centerstone of Indiana Inc located in Bloomington, IN provides extensive treatment options for adults dealing with substance use issues alongside mental health conditions, as well as support for children facing significant emotional challenges. Their specialized outpatient programs feature approaches such as 12-step support, anger management techniques, and short-term interventions. This center is committed to offering personalized care for adolescents and both men and women. It serves a diverse range of adults and seniors regardless of gender and includes outpatient options like methadone, buprenorphine, or naltrexone therapies. With an emphasis on high-quality care and customized treatment plans, Centerstone of Indiana Inc aims to assist clients in achieving sustainable recovery.

Centerstone of Indiana Inc in Greensburg, Indiana, delivers complete care for individuals struggling with addiction and co-occurring mental health conditions. They serve adults who have both substance use disorders and serious mental illnesses, as well as children facing significant emotional challenges. The center provides outpatient options, such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside cognitive behavioral therapy. Dedicated programs are available for adult men and women, and for those affected by domestic or intimate partner violence. Catering to adults and seniors across all gender identities, Centerstone of Indiana Inc emphasizes anger management, short-term support, and personalized treatment plans to foster enduring recovery. Their dedication to high standards and proven therapeutic approaches ensures they are a reliable resource for those seeking to regain their well-being.

Centerstone of Indiana Inc, located in Bloomington, IN, provides focused rehabilitation for adult men struggling with addiction and co-occurring severe mental health conditions. The center offers both residential and short-term residential care, utilizing proven methods such as 12-step facilitation, anger management techniques, and cognitive behavioral therapy. Distinctive programs are available for individuals who have faced trauma, intimate partner violence, or domestic abuse. Serving adult, senior, and young adult males, this establishment prioritizes high-quality support and tailored treatment strategies to foster recovery and overall well-being.

Centerstone of Indiana Inc, located in Madison, IN, provides extensive outpatient services for adults and youth addressing substance use concerns, alongside co-occurring mental health conditions. Their offerings encompass strategies for managing anger, cognitive behavioral techniques, and specific support for those impacted by domestic violence. The center offers outpatient medication-assisted treatment options like methadone, buprenorphine, or naltrexone, in addition to general outpatient therapy adapted for the distinct requirements of adult men and women. Emphasizing high-quality care and customized recovery paths, Centerstone of Indiana Inc supports individuals across all age groups, including seniors, who are navigating the complexities of addiction and mental wellness.

Centerstone of Illinois in Carterville, IL, delivers targeted care for adults battling substance abuse alongside severe mental health challenges, and for children experiencing emotional difficulties. They offer structured day programs and less intensive therapy options, incorporating medication-assisted treatment like methadone, buprenorphine, or naltrexone. Key therapeutic approaches include guidance in 12-step programs, techniques for managing anger, and short-term counseling, with special attention given to individuals with trauma histories. This center supports adult and youth populations, welcoming both men and women. Centerstone of Illinois is committed to providing high-quality, personalized recovery plans for comprehensive rehabilitation.

Centerstone of Indiana Inc, located in Connersville, IN, provides outpatient services for adults dealing with substance use disorders alongside significant mental health challenges, as well as emotional issues in children. Their program incorporates 12-step support, anger management strategies, and brief therapeutic interventions. This center focuses on assisting adult men and women, including those who have faced domestic violence. They offer outpatient treatment options with methadone, buprenorphine, or naltrexone, accommodating both adult and senior clients of all genders. Centerstone of Indiana Inc emphasizes high-quality care and personalized treatment plans, making it a reputable option for comprehensive rehabilitation in the Connersville area.

Centerstone of Indiana Inc, located in Rushville, IN, specializes in outpatient care for substance use disorders and offers targeted support for adults dealing with concurrent substance use and serious mental health challenges, as well as children facing significant emotional difficulties. Their therapeutic methods encompass strategies such as anger management, brief interventions, and cognitive behavioral therapy. The center provides outpatient options including methadone, buprenorphine, or naltrexone treatments alongside standard outpatient care. With specific programs designed for adult men, women, and individuals who have faced domestic violence, Centerstone serves a diverse range of adults and seniors. Emphasizing customized care and research-backed methods, the center aims to deliver top-notch treatment for those on their path to recovery.

Centerstone of Indiana Inc, located in Spencer, IN, provides a variety of outpatient programs aimed at addressing substance use disorders along with mental health challenges for both adults and youth. The center offers a range of services including 12-step programs, anger management courses, and short-term intervention strategies customized for each person. It also features specific programs designed for adult males, females, and those affected by domestic violence, ensuring a broad spectrum of support. Catering to adults and older individuals of all backgrounds, this facility emphasizes the delivery of excellent, individualized care to assist clients in their recovery journey.
Frequently Asked Questions
What is naltrexone and how does it work?
What are the most common naltrexone side effects?
What is Vivitrol and how is the injection administered?
What is the difference between naltrexone and naloxone?
How does naltrexone compare to Suboxone?
What is the standard naltrexone dosage?
How much does naltrexone cost and does insurance cover it?
What is low dose naltrexone (LDN)?
About Naltrexone (Vivitrol)
Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.
How Naltrexone Works
When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.
Naltrexone Side Effects
Common side effects include:
- Nausea, especially during the first few days
- Headache and dizziness
- Fatigue and insomnia
- Joint and muscle pain
- Decreased appetite and anxiety
Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.
Naltrexone for Alcohol Dependence
Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.
Naltrexone for Opioid Dependence
For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.
Vivitrol: Injectable Naltrexone
Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.
Vivitrol Side Effects
Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.
Revia: Oral Naltrexone Brand
Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.
Low Dose Naltrexone (LDN)
Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.
Naltrexone Cost and Insurance
Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.
Naltrexone Dosage
The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.
Naltrexone vs Naloxone: What's the Difference?
Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.
Naltrexone vs Suboxone
Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.
Naltrexone and Weight Loss
Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.
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