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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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CentraCare/Saint Cloud Hospital

CentraCare/Saint Cloud Hospital, located in Saint Cloud, MN, delivers an extensive selection of rehabilitation services for adults and youth dealing with substance use issues. The center is adept at addressing co-occurring substance use disorders in conjunction with significant mental health conditions or emotional challenges in children. Treatment options include intensive outpatient programs and outpatient day treatment, with specialized approaches such as 12-step facilitation and anger management courses. A distinguishing aspect of the center is its tailored programs for seniors and older adults, ensuring that clients of all ages receive individualized care. With a commitment to high-quality, personalized support, this center is recognized as a reliable choice for individuals seeking effective options for addiction recovery.

CentraCare/Saint Cloud Hospital

CentraCare/Saint Cloud Hospital, located in Saint Cloud, MN, provides a broad spectrum of rehabilitation services designed to meet the needs of individuals of all ages and genders. The facility focuses on treating substance use issues and related mental health disorders in both adults and youth. They offer various treatment modalities such as intensive outpatient programs, outpatient care, and day treatment. Utilizing strategies like 12-step programs and anger management, the center ensures care is tailored to the unique needs of each patient. Additionally, specialized programs for teenagers and those dealing with concurrent mental health challenges further enrich the center’s service range. Individuals seeking rehabilitation services can rely on CentraCare/Saint Cloud Hospital for high-quality, personalized care.

Central Alabama VA Healthcare System

Situated in Tuskegee, Alabama, the Central Alabama VA Healthcare System provides an extensive array of treatment services for individuals dealing with substance use issues, transitional housing needs, and co-occurring mental health disorders, for both adults and children. The offerings include intensive outpatient programs, outpatient day services, and partial hospitalization. These treatments incorporate various methods, such as 12-step support, anger management therapy, and brief interventions tailored to individual needs. The center is dedicated to serving adult men and women, along with those who have faced intimate partner or domestic violence. Emphasizing high-quality care, the center is committed to creating a nurturing atmosphere for adults and young adults across all genders in their journey towards recovery.

Central Jersey Comprehensive Trt Ctr

Central Jersey Comprehensive Trt Ctr, located in Cliffwood, NJ, offers a variety of scientifically supported treatment choices for those facing substance use challenges along with related mental health conditions. This facility features intensive outpatient services, standard outpatient treatment, and targeted methadone/buprenorphine or naltrexone therapies. Their methodology encompasses anger management techniques, brief interventions, and cognitive behavioral therapy. Specifically designed programs are available for adult men, adult women, and individuals who have undergone trauma. Catering to both adult and young adult demographics, the center ensures personalized treatment for all clients. Discover exceptional care and thorough support at Central Jersey Comprehensive Trt Ctr.

Central Kentucky Addiction Treatment

Central Kentucky Addiction Treatment, located in Danville, KY, provides outpatient detox services and substance use therapy for both adults and youth. This center is particularly skilled in addressing co-occurring substance use and severe mental health issues in adults, as well as significant emotional challenges in younger individuals. Their treatment approach encompasses brief interventions, motivational interviewing, and strategies for preventing relapse. Additionally, they offer specialized programs designed for individuals facing both chronic pain and substance use issues, as well as those who are pregnant or in the postpartum stage. Committed to delivering high-quality care, the center offers outpatient treatments with methadone/buprenorphine and naltrexone for patients of all genders.

Central City Integrated Health

Central City Integrated Health, situated in Detroit, MI, specializes in extensive addiction recovery for individuals of all ages who are concurrently facing mental health challenges. The center delivers outpatient care, including medication-assisted treatment options like methadone and buprenorphine. They also offer dedicated support for active military members, adult men, and women. Their approach incorporates proven methods such as 12-step support, anger management techniques, and short-term counseling, serving adults and young adults across the gender spectrum. Central City Integrated Health is committed to providing exceptional, customized treatment to meet each person's unique journey toward recovery.

Central Iowa Psychological Services

Central Iowa Psychological Services in Ames, IA, provides a full spectrum of recovery programs. They offer detox services, addiction treatment, and specialized support for those facing both substance use disorders and significant mental health challenges or emotional difficulties. Their adaptable treatment plans include intensive outpatient, standard outpatient, and outpatient detox options. Emphasis is placed on 12-step facilitation, anger management strategies, and brief intervention techniques. The center serves active military members, young people, and adult males. Treatment is accessible for all age groups, from children to adults, with distinct programs designed for both men and women. The commitment to high-quality care and varied therapeutic approaches positions this center as a significant resource for individuals on their journey to wellness.

Central Florida Recovery Centers

Central Florida Recovery Centers in Orlando, FL, is dedicated to aiding individuals on their journey to recovery. They provide comprehensive, research-backed therapies for detox, addiction, and intertwined mental health conditions. Their services are designed for both adults and young individuals, offering intensive outpatient, outpatient, and day treatment structures. Unique programs are available for active military personnel, teenagers, and adult men, ensuring personalized support for each demographic. Employing methods such as cognitive behavioral therapy and strategies for managing anger, the center prioritizes customized care plans. Committed to superior service and a broad spectrum of offerings, this institution creates a nurturing atmosphere for those striving to overcome addiction and mental health struggles.

Central Iowa Psychological Services

Central Iowa Psychological Services, located in West Des Moines, IA, delivers a full spectrum of recovery support for individuals of all ages. Their offerings include structured outpatient programs, accessible detox services, and specialized care for substance dependence and dual diagnoses. Dedicated tracks are available for military members, young adults, and adult men. Emphasizing proven methods like 12-step integration, emotional regulation techniques, and short-term counseling, the center is committed to personalized healing journeys. Accommodating both genders, this facility is dedicated to providing high-quality assistance for those navigating the path to recovery from addiction and mental health concerns.

Central Iowa Psychological Services

Central Iowa Psychological Services, located in West Des Moines, IA, delivers a wide range of rehabilitation options for both adults and children. The center specializes in detoxification, treatment for substance use, and offers tailored support for individuals facing concurrent substance use and mental health challenges. It features both intensive outpatient and standard outpatient programs, including detox services, to accommodate various treatment requirements. Employing methods such as 12-step support, anger management, and brief interventions, the center focuses on personalized care. Additionally, there are targeted programs for active military personnel, teenagers, and adult males. The facility serves clients of all genders and is dedicated to providing top-notch care for those on their journey toward recovery from addiction and mental health issues.

Central Maine Family Counseling PA

Situated in Lewiston, ME, Central Maine Family Counseling PA is dedicated to delivering thorough treatment for substance use disorders, as well as focused support for adults dealing with both substance-related issues and significant mental health conditions. The center also addresses emotional challenges faced by children. It offers both intensive outpatient and traditional outpatient programs, featuring treatments such as methadone, buprenorphine, or naltrexone. Utilizing various methodologies, including 12-step principles, anger management, and brief interventions, the center serves a diverse clientele, including active military personnel, adolescents, adult males, and seniors. With programs customized for each gender, this facility is committed to providing effective care and assistance for those on their journey to recovery and wellness.

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Central Behavioral Health in Norristown, PA, provides comprehensive outpatient care for adults struggling with substance use disorders. The center also addresses co-occurring mental health conditions in adults and emotional challenges in children. They offer tailored programs for active service members, teenagers, and adult men. Employing methods such as anger management, brief intervention, and cognitive behavioral therapy, Central Behavioral Health supports individuals of all ages and genders on their journey toward healing and lasting wellness.

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Central City Concern in Portland, Oregon, provides in-depth, long-term residential rehabilitation for individuals battling substance use disorders. This program is specifically designed to support adult women, seniors, and young adults who have endured intimate partner violence, domestic abuse, or sexual trauma. Through a combination of 12-step principles, anger management techniques, and cognitive behavioral therapy, the center offers a multifaceted approach to healing and recovery. Central City Concern prioritizes a nurturing atmosphere tailored to the unique challenges faced by its predominantly female clientele, establishing itself as a key provider of extended residential care in the Portland region.

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Central County Adult MH Services, located in Concord, California, provides a broad range of treatment options for adults dealing with substance use issues alongside severe mental health conditions. The center features various levels of care including intensive outpatient, outpatient, and standard outpatient programs that employ scientifically supported methods like 12-step facilitation, brief interventions, and cognitive behavioral therapy. The center offers specialized programs designed for individuals with dual diagnoses of mental health and substance use disorders, delivering customized support for both adults and young adults. With an emphasis on personalized treatment strategies and gender-sensitive care for both men and women, this center is dedicated to delivering high-quality rehabilitation services.

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Central Florida Behavioral Health, located in Tampa, FL, offers a wide range of addiction treatment services aimed at both adults and children grappling with co-occurring substance abuse and significant mental health issues. The center provides inpatient detox and treatment within a hospital setting, focusing on methods such as 12-step programs, anger management, and brief intervention techniques. Catering to various demographics, the facility features specialized plans for adolescents, as well as adult males and females, addressing the unique needs of different age groups and genders. Dedicated to delivering high-quality care, Central Florida Behavioral Health emphasizes personalized treatment approaches to foster recovery and overall wellness in a supportive rehabilitation atmosphere for adults and elderly individuals.

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Central Florida Recovery Centers, located in Apopka, FL, provides an extensive array of services for addiction treatment. The facility specializes in detox programs, recovery from substance use disorders, and dedicated support for those facing both substance-related issues and severe mental health conditions or emotional challenges. Treatment methods include various options such as intensive outpatient care, day programs, and partial hospitalization, designed for both adults and youth. The center employs diverse therapeutic techniques like anger management, brief interventions, and cognitive behavioral strategies, ensuring that each treatment plan is customized to meet individual requirements. Additionally, the center offers specialized programs for active military members, adolescents, and male adults. With a commitment to high-quality care, Central Florida Recovery Centers supports both men and women on their journey to recovery.

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Central Iowa Psychological Services, located in Ankeny, IA, provides an extensive selection of rehabilitation options. This center specializes in detoxification, treatment for substance use disorders, and focused care for patients dealing with both addiction and significant mental health challenges or emotional issues. The facility offers various treatment formats such as intensive outpatient programs, regular outpatient services, and outpatient detoxification. Emphasizing techniques like 12-step support, anger management, and brief therapeutic interventions, this facility customizes treatment strategies to meet the unique needs of each individual. There are also dedicated programs for active military personnel, teenagers, and adult males. By offering services to a diverse clientele, including both adults and children/adolescents of any gender, this center prioritizes delivering superior care with multiple specialized methodologies to facilitate recovery.

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Central Iowa Psychological Services, located in Waterloo, IA, provides an extensive array of rehabilitation options for those facing challenges with substance use and concurrent mental health issues. The center features intensive outpatient programs, outpatient detox, and customized services for both adult and youth populations. It has specialized initiatives for active military personnel, teenagers, and adult males, incorporating 12-step approaches, anger management strategies, and concise intervention methods. Clients can anticipate receiving top-notch care within a nurturing atmosphere aimed at fostering enduring recovery. There are also gender-specific programs designed for both women and men.

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Central Iowa Psychological Services, located in Knoxville, IA, provides an extensive array of addiction treatment options for both adults and children. The center features tailored programs for active military personnel, teenagers, and adult males, offering both intensive outpatient care and outpatient detox services. Their treatment methodologies encompass 12-step programs, anger management strategies, and brief intervention techniques aimed at treating co-occurring substance use disorders and significant mental health conditions. Catering to male and female clients alike, the facility prioritizes delivering personalized care that meets the specific needs of each individual. If you are looking for effective and customized addiction recovery support, this center is committed to guiding you toward sustainable healing.

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Central Iowa Psychological Services, located in Des Moines, IA, provides a complete spectrum of recovery programs for individuals of all ages struggling with addiction. Their services encompass detoxification, comprehensive substance abuse therapy, and tailored support for dual diagnoses, addressing co-occurring mental health conditions in adults or emotional challenges in young people. The facility offers various levels of care, including intensive outpatient, outpatient detox, and general outpatient treatment. Emphasizing techniques like 12-step support, anger control, and brief therapeutic approaches, their services are accessible to military members, youth, and adult males. Clients of any gender benefit from personalized attention from skilled clinicians dedicated to supporting their journey to wellness.

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Central Iowa Psychological Services in Decorah, IA, provides thorough addiction care for individuals of all ages. Services encompass detox, addiction therapy, and support for dual diagnoses involving substance abuse and mental health. Their intensive outpatient and outpatient options feature 12-step support, anger control, and short-term counseling. Dedicated programs exist for military personnel, teenagers, and adult men, offering personalized recovery paths. This center is committed to delivering excellent treatment for both men and women addressing addiction and mental wellness concerns.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

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