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Medically Reviewed Content
Updated: October 2026
Sources: SAMHSA, NIDA

Naltrexone and Vivitrol Treatment Centers

Naltrexone is an FDA-approved opioid antagonist medication used to treat both alcohol dependence and opioid use disorder. Available as a daily oral tablet (Revia) or a monthly Vivitrol injection, naltrexone works by blocking opioid receptors in the brain to reduce cravings and prevent relapse. Use our directory to find treatment centers that offer naltrexone-based medication-assisted treatment near you.

Found 6,655 treatment centers offering naltrexone (vivitrol) across the United States.

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Crossroads Treatment Centers

Crossroads Treatment Centers in Knoxville, TN, delivers accessible outpatient substance abuse recovery programs. Their approach centers on preventing setbacks and providing expert guidance for addiction. Services include medication-assisted treatment (methadone, buprenorphine, naltrexone), with the added convenience of remote counseling sessions. The center is particularly dedicated to supporting expectant and new mothers, serving adults and young adults across all gender identities. Crossroads Treatment Centers is dedicated to fostering a nurturing space for those on their journey to sobriety, with personalized care designed for individual circumstances.

Crouse Health Hospital Inc

Crouse Health Hospital Inc, located in Syracuse, NY, provides expert care for substance use disorders through its outpatient services. The center offers treatment options that include outpatient methadone/buprenorphine and naltrexone therapies, alongside general outpatient programs. Prioritizing methods such as anger management, cognitive behavioral therapy, and motivational interviewing, this facility customizes its approach to best serve individual clients. There are specialized programs available for adolescents, adult men, and adult women. Catering to individuals of all ages and genders, Crouse Health Hospital Inc ensures a nurturing atmosphere for recovery. If you are looking for effective and personalized addiction treatment, Crouse Health Hospital Inc may be the right choice for you.

Crusader Community Health

Crusader Community Health, situated in Rockford, Illinois, provides outpatient services for adults dealing with substance use issues, including individuals facing significant mental health challenges simultaneously. The center has developed specialized programs aimed at young adults, emphasizing a personalized treatment strategy. They are proficient in delivering cognitive behavioral therapy, motivational interviewing techniques, and short-term intervention plans. By prioritizing high-quality care, Crusader Community Health offers custom outpatient treatment options using methadone/buprenorphine or naltrexone, facilitating a targeted and productive recovery process for clients of all genders.

Cumberland Heights
Nashville, TN

Cumberland Heights, situated in Nashville, TN, provides a wide range of addiction recovery services tailored for adults and young adults. The center specializes in detox and treatment for substance use, offering various options such as intensive outpatient, outpatient, and day treatment programs. Emphasizing methodologies like 12-step facilitation, anger management training, and brief intervention, the facility serves both male and female clients, including those who have faced traumatic experiences. Cumberland Heights is particularly noted for its dedicated programs for men, women, and trauma survivors, ensuring that each individual receives personalized care. Committed to high-quality and research-driven treatment methods, this center is focused on assisting clients throughout their recovery process.

Crownpoint Healthcare Facility

Crownpoint Healthcare Facility, situated in Crownpoint, NM, delivers expert outpatient rehabilitation. This establishment focuses on addressing substance dependence alongside significant mental health conditions or emotional struggles for both younger and adult individuals. Their therapeutic approach incorporates strategies like anger management, short-term interventions, and cognitive behavioral techniques, serving adolescents, adult males, and females. Specialized treatment pathways are designed for adults and elderly individuals, accommodating all genders. Crownpoint Healthcare Facility is dedicated to providing excellent care and customized recovery plans for those navigating addiction and mental health concerns.

Crossroads Turning Points Inc

Crossroads Turning Points Inc. in Alamosa, CO, delivers extensive addiction recovery programs for adults and older individuals. They offer detox services, substance use disorder therapy, and tailored support for adults dealing with co-occurring substance use and severe mental health conditions, along with children experiencing emotional difficulties. Services include intensive outpatient and outpatient treatment, as well as medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center employs therapeutic methods such as 12-step facilitation, anger management, and brief intervention to provide personalized recovery plans. Dedicated programs are provided for teenagers, adult men, and adult women, serving a broad spectrum of individuals. Crossroads Turning Points Inc. is recognized for its commitment to high-quality care and customized treatment paths, making it a significant resource for individuals pursuing successful addiction recovery.

Cumberland Heights
Nashville, TN

Cumberland Heights, located in Nashville, TN, specializes in outpatient care for adults dealing with substance abuse and co-existing mental health disorders, as well as emotional challenges in children. The center offers a range of therapeutic options such as outpatient services for methadone and buprenorphine, 12-step programs, and measures for anger management. Emphasizing tailored treatment, Cumberland Heights serves both adults and young adults across the gender spectrum. Their holistic methodology integrates proven techniques within a nurturing environment, aiming to support clients in achieving sustainable recovery. For those in search of customized and effective addiction support, this center is committed to delivering quality care specifically designed to meet the unique needs of each person.

Cumberland Heights
Brentwood, TN

Cumberland Heights, situated in Brentwood, TN, delivers targeted substance abuse recovery services for adults and teens. Their offerings include comprehensive outpatient care, general outpatient support, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. Emphasizing 12-step integration, emotional regulation skills, and concise therapeutic interventions, Cumberland Heights serves both men and women. A key feature is their distinct programming for adolescents, providing tailored assistance for young people facing addiction challenges. Cumberland Heights is committed to providing excellent, gender-tailored care to guide individuals toward lasting sobriety.

Crossroads Treatment Centers

Crossroads Treatment Centers in Memphis, TN, delivers comprehensive outpatient care for substance use disorders, utilizing medication-assisted treatments such as methadone, buprenorphine, and naltrexone. They equip clients with relapse prevention techniques, offer individual and group counseling for addiction, and provide telehealth options for greater accessibility. This center is particularly dedicated to serving pregnant and postpartum women, while also extending support to adult and young adult individuals across all genders. Crossroads Treatment Centers in Memphis is committed to delivering personalized treatment plans within a nurturing atmosphere, positioning it as a premier destination for those pursuing successful and empathetic recovery from addiction.

Crossroads Turning Points Inc

Crossroads Turning Points Inc, located in Pueblo, CO, delivers a complete spectrum of addiction recovery assistance. This establishment provides medically supervised withdrawal, comprehensive substance misuse care, and dedicated support for individuals facing both addiction and significant mental health conditions in adults, or emotional challenges in youth. Their therapeutic offerings encompass intensive outpatient, extended residential stays, and regular outpatient services. The center employs proven therapeutic modalities including strategies for managing anger, prompt intervention techniques, and cognitive behavioral therapy. Catering to specific age groups and needs, including adolescents, adult males and females, and all adults and older adults regardless of gender, Crossroads Turning Points Inc is committed to delivering personalized treatment and encouragement to everyone they serve.

Crouse Health Hospital Inc

Crouse Health Hospital Inc in Syracuse, NY offers robust inpatient substance use disorder care for adults, encompassing young adults, men, and women. Employing proven methods like CBT, motivational interviewing, and relapse prevention, their programs are customized for each patient's unique journey. The center emphasizes gender-specific support within its hospital-based recovery setting, providing a nurturing space for those pursuing lasting sobriety.

Crown Medical Support Services

Crown Medical Support Services, situated in Minneapolis, MN, provides dedicated rehabilitation programs designed for individuals grappling with substance use issues and related mental health challenges, catering to both adults and children. Emphasizing intensive outpatient treatment, the center also offers outpatient services and medication-assisted therapies. It incorporates proven methods like anger management techniques, cognitive behavioral therapy, and motivational interviewing into its programs. Customized plans for active-duty military members, as well as specialized care for adult men and women, are a hallmark of this facility. Crown Medical Support Services is committed to delivering thorough and high-quality care, assisting individuals across all genders as they navigate their recovery journey.

Crossroads Turning Points Inc

Crossroads Turning Points Inc in Lamar, CO, specializes in treating substance use disorders and co-occurring mental health issues for both adults and children. The center offers various treatment programs, including intensive outpatient care, outpatient services, and options for methadone, buprenorphine, or naltrexone. By emphasizing methods such as 12-step programs, anger management, and brief interventions, the facility serves a diverse population that includes adolescents, adult men, and women. Catering to individuals across different gender identities, this center provides personalized care designed to address specific needs. The high standard of care and unique services available at this facility make it an essential option for those in need of thorough addiction rehabilitation and mental health assistance.

Cumberland Hall Hospital
Hopkinsville, KY

Cumberland Hall Hospital, located in Hopkinsville, KY, provides a wide range of addiction recovery programs aimed at adults as well as children and adolescents dealing with substance abuse and related mental health concerns. The center features inpatient detox and therapeutic services, offering specialized support for active duty military personnel, teens, and adult males. Emphasizing personalized care, the facility incorporates methods such as 12-step facilitation, anger management, and short intervention strategies. Cumberland Hall Hospital is committed to delivering high-quality treatment, with programs designed specifically for men and women. Opt for this establishment to access research-backed therapies within a nurturing setting that promotes enduring recovery.

Cumberland Mountain Comm Servs Board

Cumberland Mountain Comm Servs Board in Grundy, VA, delivers extensive outpatient care for adults battling substance use disorders who also experience significant mental health challenges. Their expertise includes cognitive behavioral techniques, motivational guidance, and strategies to prevent relapse. This center provides personalized support to all clients, accommodating various age groups from young adults to older adults. Offering outpatient medication-assisted treatment with methadone, buprenorphine, or naltrexone, the facility emphasizes a complete recovery journey. Patients discover a nurturing atmosphere focused on their individual recovery paths, establishing Cumberland Mountain Comm Servs Board as a leading provider of specialized and tailored recovery solutions.

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Crossroads to Recovery, located in Brooklyn, NY, provides comprehensive outpatient and intensive outpatient treatment for substance use issues, targeting both adults and young adults. The center is particularly adept at addressing co-occurring substance use and serious mental health disorders in adults, as well as significant emotional challenges in children. Emphasizing methods such as anger management, short-term interventions, and cognitive behavioral therapy, the facility delivers personalized treatment plans designed for each individual. Additionally, distinct programs are available for individuals who have faced intimate partner violence, domestic violence, and those involved in the criminal justice system. Crossroads to Recovery welcomes clients of all genders, promoting an inclusive approach to the rehabilitation process for everyone.

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Crouse Health Hospital Inc, situated in Syracuse, NY, specializes in offering targeted substance use recovery programs designed for both adults and young adults. This center provides various outpatient services, such as outpatient day treatment, partial hospitalization, and treatments using methadone/buprenorphine or naltrexone. Their treatment methodology involves techniques like anger management, cognitive behavioral therapy, and motivational interviewing to effectively handle addiction challenges. Crouse Health Hospital Inc also features distinct programs aimed at adult men, adult women, and individuals who have faced trauma, ensuring personalized treatment plans. By emphasizing gender-specific care for both genders, the center remains dedicated to delivering high-quality and comprehensive rehabilitation support.

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Situated in Crowley, LA, the Crowley Behavioral Health Clinic provides outpatient treatment for substance use disorders in both adults and children dealing with concurrent mental health challenges. The services offered encompass anger management, brief intervention techniques, and cognitive behavioral therapy. This center serves a diverse clientele including active duty military members, teenagers, adult males, and seniors. Emphasizing quality care, the clinic features tailored treatment programs for both men and women. For those in search of thorough addiction support within a nurturing setting, the Crowley Behavioral Health Clinic is committed to guiding individuals toward sustained recovery.

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Crowleys Ridge Development Council Inc, located in Jonesboro, AR, provides a wide array of substance use rehabilitation services for both adults and young adults. The center features intensive outpatient programs, outpatient day programs, and partial hospitalization, employing evidence-backed methods such as 12-step facilitation and anger management techniques. It has a special emphasis on addressing both substance use and serious mental health issues, including emotional challenges in children. This facility supports adult men and women who are looking for a nurturing atmosphere conducive to healing. Committed to delivering high-quality care and personalized treatment strategies, the center also offers transitional housing and sober living arrangements to accommodate a variety of client needs.

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Cumberland County Alc and Drug Center, situated in Bridgeton, NJ, provides a variety of substance use treatment options, including intensive outpatient, outpatient, and standard outpatient programs. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, the center caters to specialized needs of adolescents, adult men, and adult women. It serves a diverse population, including adults and children/adolescents across all genders, ensuring personalized care that meets each individual's requirements. Whether you are looking for assistance for yourself or someone else, Cumberland County Alc and Drug Center offers a supportive environment and extensive treatment solutions to facilitate the recovery process.

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Situated in Fayetteville, NC, Cumberland County CommuniCare features a wide array of treatment options for both adults and children facing substance use challenges alongside mental health disorders. The center offers various levels of outpatient care, including intensive and regular outpatient programs, all designed to meet the unique needs of each individual. With methodologies like cognitive behavioral therapy, anger management, and brief interventions, this facility prioritizes customized treatment for all clients. Additionally, specialized programs are available for active military personnel, adolescents, and adult males. Cumberland County CommuniCare is committed to providing exceptional rehabilitation services to adults and seniors of all genders who require assistance.

Frequently Asked Questions

What is naltrexone and how does it work?
Naltrexone is an opioid antagonist medication approved by the FDA to treat both alcohol use disorder and opioid dependence. It works by binding to opioid receptors in the brain, blocking the euphoric and sedative effects of opioids and reducing alcohol cravings. Naltrexone is available as an oral tablet (brand name Revia) and as a monthly injection (brand name Vivitrol).
What are the most common naltrexone side effects?
The most common naltrexone side effects include nausea, headache, dizziness, fatigue, insomnia, and anxiety. Some patients also experience joint or muscle pain, decreased appetite, and stomach cramps. Most side effects are mild and tend to diminish within the first few weeks of treatment. Serious but rare side effects include liver damage, so physicians typically monitor liver function during treatment.
What is Vivitrol and how is the injection administered?
Vivitrol is the brand name for extended-release naltrexone, delivered as a once-monthly intramuscular injection. The Vivitrol injection is administered by a healthcare provider into the gluteal muscle and slowly releases naltrexone over approximately 30 days. This eliminates the need for daily pill compliance, making it a preferred option for many patients in recovery from alcohol or opioid dependence.
What is the difference between naltrexone and naloxone?
Although their names sound similar, naltrexone and naloxone serve different purposes. Naloxone (brand name Narcan) is a short-acting opioid antagonist used as an emergency rescue medication to reverse opioid overdoses, while naltrexone is a long-acting antagonist taken on a scheduled basis to prevent relapse. Naloxone works within minutes but wears off quickly, whereas naltrexone provides sustained receptor blockade over hours or weeks depending on the formulation.
How does naltrexone compare to Suboxone?
Naltrexone and Suboxone take fundamentally different approaches to treating opioid dependence. Suboxone contains buprenorphine (a partial opioid agonist) and reduces withdrawal symptoms by mildly activating opioid receptors, while naltrexone fully blocks those receptors without any opioid effect. Patients must be fully detoxed from opioids before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. The best choice depends on individual treatment history and clinical needs.
What is the standard naltrexone dosage?
The standard oral naltrexone dosage for both alcohol and opioid dependence is 50 mg taken once daily. Some providers use an initial dose of 25 mg for the first day to minimize side effects. For Vivitrol, the dosage is 380 mg delivered as a single intramuscular injection once every four weeks. Dosage should not be adjusted without medical supervision.
How much does naltrexone cost and does insurance cover it?
Generic oral naltrexone tablets typically range from $30 to $80 per month without insurance. Vivitrol injections are considerably more expensive, often costing $1,000 to $1,800 per injection without coverage. Most private insurance plans, Medicaid, and Medicare cover naltrexone in both forms, and manufacturer assistance programs are available for eligible patients.
What is low dose naltrexone (LDN)?
Low dose naltrexone (LDN) refers to naltrexone taken at very small doses, typically between 1 mg and 5 mg, far below the standard 50 mg addiction treatment dose. LDN is used off-label for conditions such as chronic pain, fibromyalgia, and certain autoimmune disorders, and it is not an approved treatment for addiction. Patients should not confuse LDN with standard naltrexone therapy for substance use disorders.

About Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist, meaning it binds to the mu-opioid receptors in the brain without activating them. By occupying these receptors, naltrexone effectively blocks the rewarding effects of opioids and reduces the neurochemical reinforcement that drives alcohol cravings. Unlike medications such as methadone or buprenorphine, naltrexone has no potential for abuse or physical dependence because it produces no opioid effect whatsoever.

How Naltrexone Works

When a person taking naltrexone consumes alcohol, the pleasurable dopamine surge that normally reinforces drinking behavior is significantly blunted. For individuals with opioid dependence, naltrexone prevents any ingested opioid from reaching the receptors, rendering opioid use ineffective. This pharmacological mechanism makes naltrexone a cornerstone of medication-assisted treatment (MAT) programs across the country. Naltrexone was first approved by the FDA in 1984 for opioid dependence and received additional approval for alcohol dependence in 1994.

Naltrexone Side Effects

Common side effects include:

  • Nausea, especially during the first few days
  • Headache and dizziness
  • Fatigue and insomnia
  • Joint and muscle pain
  • Decreased appetite and anxiety

Serious side effects are less common but include signs of liver injury such as yellowing of the skin or eyes, dark urine, and persistent abdominal pain. Severe injection site reactions from Vivitrol, including tissue necrosis, have been reported in rare cases. Importantly, naltrexone lowers opioid tolerance over time — if a person discontinues naltrexone and attempts to use opioids at previously tolerated doses, the risk of fatal overdose increases significantly.

Naltrexone for Alcohol Dependence

Naltrexone is one of only three FDA-approved medications for alcohol use disorder, alongside disulfiram (Antabuse) and acamprosate (Campral). For individuals struggling with alcohol dependence, naltrexone reduces heavy drinking days and increases the percentage of days abstinent. The oral formulation, sold under the brand name Revia, is typically prescribed at 50 mg daily and is most effective when combined with behavioral therapy and support groups.

Naltrexone for Opioid Dependence

For opioid dependence, naltrexone serves as a relapse-prevention tool rather than a detox medication. Patients must complete a full opioid detoxification and remain opioid-free for a minimum of 7 to 14 days before beginning naltrexone therapy. Starting naltrexone while opioids are still present can trigger sudden and severe precipitated withdrawal. Once initiated, naltrexone provides a pharmacological safety net — if a patient relapses, naltrexone blocks the drug from producing its usual effects.

Vivitrol: Injectable Naltrexone

Vivitrol is the brand name for naltrexone extended-release injectable suspension, delivering 380 mg in a single intramuscular dose once per month. A healthcare provider injects Vivitrol into the gluteal muscle using a special needle included in the product kit, alternating sides each month. The Vivitrol shot has become increasingly popular because it solves one of the biggest challenges in addiction treatment: medication adherence. Studies show that patients receiving monthly Vivitrol injections are significantly more likely to remain in treatment compared to those prescribed daily oral naltrexone.

Vivitrol Side Effects

Vivitrol shares many side effects with oral naltrexone but carries additional risks related to the injection site. These range from mild tenderness, redness, and swelling to severe complications including induration and in rare cases tissue necrosis requiring surgical intervention. As with oral naltrexone, Vivitrol can affect liver function, and depressed mood and suicidal thoughts have also been reported.

Revia: Oral Naltrexone Brand

Revia is the primary brand name for oral naltrexone hydrochloride tablets in a 50 mg strength. Today, most prescriptions are filled with generic naltrexone, which is bioequivalent and significantly less expensive. The main advantage of oral naltrexone over injectable Vivitrol is lower cost and greater dosing flexibility, but it requires daily compliance, which patients in early recovery frequently struggle with.

Low Dose Naltrexone (LDN)

Low dose naltrexone (LDN) refers to naltrexone prescribed at doses ranging from 0.5 mg to 5 mg — a fraction of the standard 50 mg addiction treatment dose. LDN is used off-label and is not FDA-approved for any condition at these low doses. It is not a treatment for addiction and operates through a fundamentally different mechanism. The theory proposes that a brief, transient blockade of opioid receptors causes a rebound effect that increases the body's natural endorphin production. LDN has been investigated for conditions including fibromyalgia, multiple sclerosis, and Crohn's disease, but large-scale clinical trials are still needed.

Naltrexone Cost and Insurance

Generic oral naltrexone typically costs $30 to $80 per month without insurance. With insurance or discount programs, out-of-pocket cost can fall below $15. Vivitrol injections cost $1,000 to $1,800 without insurance, but most private plans, Medicaid, and Medicare cover it. Alkermes offers the Vivitrol Co-Pay Savings Program for insured patients and a Patient Assistance Program for those without insurance.

Naltrexone Dosage

The standard oral dose is 50 mg once daily, with some providers starting at 25 mg for the first day to minimize side effects. For Vivitrol, the dose is 380 mg as a single intramuscular injection every four weeks. Patients must be opioid-free for a minimum of 7 to 14 days before initiating either formulation.

Naltrexone vs Naloxone: What's the Difference?

Both are opioid antagonists, but they differ in duration and use. Naloxone (Narcan) is a short-acting emergency overdose reversal agent that takes effect within minutes and wears off in 30 to 90 minutes. Naltrexone is a long-acting antagonist for ongoing relapse prevention, providing blockade for 24 hours (oral) or 30 days (Vivitrol). Naloxone is also a component of Suboxone, where it deters injection misuse.

Naltrexone vs Suboxone

Suboxone contains buprenorphine (a partial opioid agonist) that mildly stimulates opioid receptors, reducing cravings and withdrawal. Naltrexone fully blocks receptors with zero agonist activity. Patients must be fully detoxed before starting naltrexone, whereas Suboxone can be initiated during early withdrawal. A landmark 2017 clinical trial (X:BOT) found that among patients who successfully started treatment, relapse rates were similar between Vivitrol and Suboxone.

Naltrexone and Weight Loss

Naltrexone is one of two active ingredients in Contrave (naltrexone/bupropion), an FDA-approved weight management medication. However, naltrexone alone is not approved for weight loss. Some patients undergoing addiction treatment report modest weight changes related to reduced alcohol calories or appetite-suppressing side effects, but naltrexone should not be selected as an addiction medication primarily for weight effects.

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Medically Reviewed Updated October 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)