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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.

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ADAPT Counseling Services

ADAPT Counseling Services located in Evansville, IN, delivers an extensive range of substance abuse treatment for both adults and children facing concurrent mental health issues. The center features a variety of treatment formats, including intensive outpatient, outpatient, and standard outpatient programs that employ proven methods like 12-step facilitation, anger management, and brief intervention. ADAPT also offers specialized programs aimed at active duty military members, adolescents, and adult men, accommodating a wide spectrum of ages and genders, including both women and men. With an emphasis on personalized care and a nurturing atmosphere, the facility is dedicated to providing high-quality treatment for those in need of effective and empathetic rehabilitation support.

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Situated in Port Orford, OR, Adapt Integrated Healthcare delivers thorough treatment for substance use disorders via outpatient programs. The facility employs various evidence-based methods, including brief interventions, cognitive behavioral therapy, and motivational incentives to facilitate recovery. A distinguishing feature of this center is its tailored approach, accommodating adults as well as children and adolescents of diverse gender identities. With an emphasis on individualized care, Adapt Integrated Healthcare is committed to providing exceptional treatment that aids individuals on their path to recovery. If you're looking for efficient addiction support in a nurturing atmosphere, this center is focused on helping you attain enduring sobriety.

Adapt Integrated Healthcare

Adapt Integrated Healthcare, located in Roseburg, OR, provides outpatient services for substance use disorders, emphasizing 12-step support, short-term interventions, and motivational interviewing techniques. This center focuses on programs designed for adolescents and young adults, accommodating clients of all genders. It offers a holistic approach to recovery, addressing the needs of adults as well as children and teenagers. The committed staff at Adapt Integrated Healthcare delivers exceptional care and assistance to those looking to overcome their addiction challenges.

Adapt Integrated Healthcare

Adapt Integrated Healthcare, situated in Roseburg, OR, provides a comprehensive suite of empirically supported therapeutic interventions. This institution focuses on addressing addiction and co-occurring mental health conditions in both pediatric and adult populations. They offer various levels of care, including intensive outpatient and standard outpatient programs, and administer medication-assisted treatment such as methadone and buprenorphine. Their specialized therapeutic approaches encompass anger management, cognitive behavioral therapy, and brief intervention strategies. Adapt Integrated Healthcare welcomes adult men and women, including survivors of domestic abuse, and extends its services to young adults of any gender, fostering a nurturing setting for holistic recovery.

Adapt Integrated Healthcare

Adapt Integrated Healthcare in Roseburg, OR, provides extended stay and round-the-clock residential care for young individuals struggling with substance dependency. Their approach integrates methods such as 12-step facilitation, brief intervention, and motivational incentives. They also offer tailored services for individuals with a history of trauma and those dealing with combined mental health and addiction challenges. This facility is committed to delivering high-quality, gender-specific treatment, offering robust support for those seeking specialized recovery services.

Adapt Integrated Healthcare

Integrated Healthcare in North Bend, OR, delivers personalized outpatient care for substance use disorders. They offer distinct programs for adult men, adult women, and individuals with trauma histories, fostering a nurturing setting for healing. Employing evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and contingency management, the center prioritizes holistic recovery. Their services extend to both adults and young adults, accommodating both genders. This commitment to high-quality, individualized treatment establishes Integrated Healthcare as a crucial support for individuals pursuing successful addiction recovery in the North Bend region.

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In Grants Pass, OR, Adapt Integrated Healthcare provides excellent substance abuse rehabilitation using methods such as anger management, brief intervention, and cognitive behavioral therapy. This establishment supports adult men, adult women, and individuals affected by intimate partner and domestic violence. Adapt Integrated Healthcare offers intensive outpatient, outpatient, and standard outpatient programs for adults and young people of any gender. Prioritizing personalized care and scientifically supported treatments, Adapt Integrated Healthcare is a reliable choice for those pursuing effective and thorough recovery programs.

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Adapt Integrated Healthcare in Gold Beach, OR, delivers specialized outpatient care for substance use disorders, prioritizing a tailored approach for every individual. Their regular outpatient services employ proven methods like brief intervention, cognitive behavioral therapy, and motivational incentive programs. Catering to adults, children, and adolescents across all genders, this facility offers complete support. Adapt Integrated Healthcare is committed to providing excellent, customized addiction treatment that addresses each client's specific requirements.

Adapt Integrated Healthcare

Adapt Integrated Healthcare, situated in North Bend, OR, stands as a premier facility dedicated to overcoming substance abuse challenges. They provide a spectrum of care, including intensive outpatient, outpatient, and standard outpatient services for both young people and adults. Their approach integrates specialized interventions such as anger management, brief intervention, and cognitive behavioral therapy, ensuring personalized treatment plans that address the distinct requirements of every individual. The center also features dedicated support for adult men and women, as well as those affected by intimate partner or domestic violence. Offering gender-specific programs for all clients, Adapt Integrated Healthcare cultivates a nurturing setting. Their commitment lies in offering effective, research-supported care to guide individuals toward a successful recovery journey.

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Adapt Integrated Healthcare in Roseburg, OR, provides extensive substance abuse recovery options via personalized outpatient care. Their services include medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside standard outpatient therapy. They employ proven techniques like cognitive behavioral therapy, contingency management, and motivational interviewing. Specialized support is available for adult men, adult women, and individuals with trauma histories. Adapt Integrated Healthcare welcomes adults and young adults of all genders, offering dedicated and supportive addiction treatment in an affirming setting.

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Adapt Integrated Healthcare, situated in Brookings, OR, delivers outpatient care for individuals of all ages struggling with substance use disorders. They employ therapeutic strategies including brief intervention, cognitive behavioral therapy, and contingency management, often referred to as motivational incentives. Their approach emphasizes personalized treatment plans, designed to address the specific circumstances of every patient. Adapt Integrated Healthcare is committed to providing effective, research-supported addiction services in a supportive setting for anyone pursuing lasting sobriety.

Adapt Integrated Healthcare

Adapt Integrated Healthcare, situated in Roseburg, Oregon, delivers a full spectrum of detox and addiction recovery services. They offer hospital-based inpatient detox, treatment, and round-the-clock support for adults and young adults. The center features tailored programs for active military members, as well as separate tracks for adult men and women, addressing a variety of circumstances. Employing methods like 12-step encouragement, emotional regulation techniques, and brief counseling, this establishment ensures individualized support. Adapt Integrated Healthcare is dedicated to providing effective, research-backed care for all clients, aiding their path to sustained wellness.

ADAPT MOTS only Madrone

Madrone, located in Roseburg, OR, delivers extensive treatment for substance abuse and is proficient in addressing co-occurring disorders among both adults and children. This center features adaptable outpatient options, which include intensive outpatient programs and medication-assisted treatment. Emphasizing tools such as 12-step facilitation, anger management, and short interventions, the facility customizes its approach to meet each person's specific needs. It also offers distinct programs for active military members, adult men and women, and services tailored for children and teenagers, ensuring focused care for every individual. With a strong commitment to high-quality treatment and a variety of specialized methods, Madrone is resolute in assisting individuals throughout their recovery process.

Adapt Programs
Los Angeles, CA

Adapt Programs, situated in Los Angeles, California, provides outpatient care for substance use disorders. Their treatment strategies incorporate proven methods like anger management, brief intervention, and motivational incentives. The center serves a broad clientele, encompassing military members, young individuals, and adult males. Adapt Programs features distinct programs for adults and younger individuals of any gender, ensuring personalized and complete support tailored to each person's specific requirements. For those in the Los Angeles region looking for addiction recovery services, Adapt Programs stands out due to its excellent care and customized treatment paths.

ADAPT Psychology Inc

ADAPT Psychology Inc, located in Henderson, KY, specializes in outpatient services for individuals dealing with substance use challenges and concurrent mental health conditions in adults, along with severe emotional issues in children. The center employs methods such as 12-step facilitation, anger management techniques, and brief interventions to create customized treatment plans for men, women, and seniors. With specific initiatives for active military personnel and adolescents, ADAPT Psychology Inc prioritizes person-centered care, ensuring that rehabilitation services are thorough and nurturing. Clients are welcomed into a supportive environment that promotes recovery and well-being for anyone in need of assistance.

AdCare Hospital
Warwick, RI

AdCare Hospital, located in Warwick, Rhode Island, specializes in outpatient treatment for substance abuse and provides targeted assistance for adults dealing with both substance use disorders and significant mental health issues, as well as emotional disturbances in minors. The center employs a variety of techniques, including 12-step support, anger management strategies, and brief intervention methods. They offer personalized programs designed for adult men, adult women, and clients facing co-occurring disorders, ensuring that each individual receives the care they need. This facility caters to both adult and young adult clients, focusing on delivering high-quality care and extensive support for individuals on their journey to recover from addiction and mental health difficulties.

AdCare Hospital
Worcester, MA

Nestled in Worcester, MA, AdCare Hospital delivers a full spectrum of addiction recovery programs for adults and adolescents. They excel in medical detox, comprehensive substance abuse treatment, and care for dual diagnoses. This inpatient facility emphasizes 12-step integration, anger management techniques, and short-term intervention strategies. AdCare Hospital features distinct tracks for adult males, adult females, and those experiencing co-occurring conditions, addressing a variety of individual requirements. Their commitment to high-standard care and personalized recovery pathways positions them as a premier destination for those pursuing successful rehabilitation within a nurturing setting.

AdCare Outpatient

Located in Warwick, RI, AdCare Outpatient delivers an array of effective treatment options for individuals dealing with substance use issues and concurrent mental health conditions. The center features dedicated tracks for both adults and young adults, offering various levels of care including intensive outpatient, outpatient, and standard outpatient services. Employing strategies such as 12-step programs, anger management techniques, and brief interventions, AdCare Outpatient serves a diverse clientele, accommodating both men and women, including adult females. The center’s emphasis on addressing co-occurring disorders distinguishes its approach, ensuring thorough care for patients experiencing multifaceted challenges. AdCare Outpatient is committed to providing high-quality, personalized treatment aimed at fostering enduring recovery.

AdCare Outpatient
Worcester, MA

AdCare Outpatient in Worcester, MA, provides robust outpatient treatment for individuals grappling with substance use and concurrent mental health conditions. They serve adults and young adults with distinct programs for men, women, and those experiencing dual diagnoses. Employing methodologies such as 12-step support, emotional regulation techniques, and short-term counseling, the center delivers thorough and customized care. They offer various levels of care, including outpatient, day programs, and partial hospitalization, all delivered with a commitment to gender-specific services. AdCare Outpatient is dedicated to using proven therapeutic strategies and developing individualized recovery plans, promoting successful rehabilitation for those facing addiction and mental wellness issues.

AdCare Rhode Island Inc

AdCare Rhode Island Inc, located in Wakefield, RI, specializes in treating individuals with substance use issues and co-occurring mental health disorders for both adults and children. The center features a range of programs including intensive outpatient, outpatient, and partial hospitalization, employing evidence-based methods such as 12-step facilitation and anger management techniques. AdCare caters to the specific needs of various groups, including active duty military personnel, adult men and women. This facility focuses on providing high-quality, personalized care to ensure successful recovery for individuals of all genders. Whether individuals require substance use treatment or combined mental health services, AdCare Rhode Island Inc delivers thorough support in a nurturing setting.

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AdCare Rhode Island Inc, located in Greenville, RI, focuses on providing targeted treatment for substance use and co-occurring mental health disorders in both adults and children facing emotional challenges. The center offers a variety of programs, including intensive outpatient, outpatient, and standard outpatient options, employing established techniques such as cognitive behavioral therapy, brief interventions, and anger management. With specific programs designed to meet the needs of adult men, women, and individuals with dual diagnoses, this center serves a diverse population of adults and seniors. AdCare Rhode Island Inc is distinguished by its thorough care, personalized treatment strategies, and dedication to high-quality service, positioning it as a leading option for individuals in need of effective rehabilitation support.

Frequently Asked Questions

What is Medication-Assisted Treatment (MAT)?
MAT combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction treatment. Medications normalize brain chemistry, block euphoric effects of substances, relieve physiological cravings, and normalize body functions without negative effects of substance use. MAT is the gold standard for opioid and alcohol use disorders.
What medications are used in MAT?
For opioid use disorder: methadone, buprenorphine (Suboxone, Sublocade), and naltrexone (Vivitrol). For alcohol use disorder: naltrexone, acamprosate, and disulfiram. Each medication has unique benefits and considerations. A physician experienced in addiction medicine determines the most appropriate option based on individual circumstances, substance used, and treatment goals.
Is MAT just replacing one addiction with another?
No, this is a common misconception. MAT medications are prescribed at stable, therapeutic doses and don't produce euphoria when taken as directed. They're medicine, not substitution. MAT allows normal functioning, eliminates cravings, prevents withdrawal, dramatically reduces overdose risk, and enables engagement in therapy and rebuilding life. Research consistently shows MAT saves lives and improves outcomes.
How long does MAT last?
MAT duration varies by individual needs. Some people benefit from months of treatment, others years or indefinitely. There's no predetermined timeline. Research shows longer MAT duration improves outcomes and reduces overdose risk. Decisions about duration should be made collaboratively with healthcare providers based on stability, quality of life, and recovery goals, not arbitrary timelines.
Does insurance cover MAT?
Most health insurance plans cover MAT under mental health and substance use benefits. The Affordable Care Act and Mental Health Parity Act require coverage for addiction treatment including MAT. Coverage includes medications, office visits, counseling, and therapy. Contact your insurance provider or treatment center admissions to verify specific coverage and costs.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

Harm Reduction and Medication-Assisted Treatment

Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.

Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.

Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.

MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.

FDA-Approved Medications: Detailed Guides

The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.

Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.

Learn more about Naltrexone →

Buprenorphine (Suboxone)

Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.

Learn more about Buprenorphine →

Methadone

Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.

Learn more about Methadone →

Naloxone (Narcan)

Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.

Learn more about Naloxone →

MAT resources and information:

Find Medication-Assisted Treatment (MAT) by State

Browse medication-assisted treatment (mat) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)