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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.

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ACTS Behavioral Health and

Situated in Lynnwood, WA, ACTS Behavioral Health specializes in outpatient services for adults facing substance use challenges alongside significant mental health disorders, as well as for children experiencing serious emotional disturbances. Utilizing evidence-based methodologies such as anger management, brief intervention, and cognitive behavioral therapy, this center develops personalized programs for each individual. Catering to a diverse range of clients, including adults and children/adolescents of all genders, ACTS Behavioral Health is committed to delivering high-quality care through customized treatment plans. If you or someone you know is in need of thorough and effective addiction support, this program may be the ideal option for you.

ACTS Behavioral Health and

In Lakewood, WA, ACTS Behavioral Health provides comprehensive treatment programs for adults struggling with substance use and co-occurring mental health conditions, as well as for children with serious emotional disturbances. Their services encompass intensive outpatient, outpatient, and regular outpatient levels of care. Utilizing therapeutic approaches such as anger management, brief intervention, and cognitive behavioral therapy, ACTS Behavioral Health delivers tailored support. They offer personalized treatment plans for adults and children, accommodating both male and female clients who are looking for effective addiction recovery and mental health support in a nurturing setting.

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The Acute Stabilization Unit in Providence, RI, offers dedicated substance use treatment and dual diagnosis support for individuals of all ages. Their residential and short-term residential options employ techniques like brief intervention, cognitive behavioral therapy, and relapse prevention. Specialized tracks are provided for adult men, women, and those with a history of trauma. The center also offers gender-specific programming for adults and young adults, encompassing both male and female clients. The Acute Stabilization Unit is committed to providing effective, personalized care aimed at fostering recovery and enhancing general health.

Adams Behavioral Health

Located in Decatur, IN, Adams Behavioral Health provides outpatient services aimed at treating substance abuse and concurrent mental health issues in both adults and children. The center employs techniques like cognitive behavioral therapy, motivational interviewing, and anger management to deliver personalized treatment that meets diverse needs. It also features specialized programs designed for clients involved with the criminal justice system. Catering to adults and senior individuals regardless of gender, the facility emphasizes high-quality care grounded in evidence-based methods. Committed to a holistic approach to healing and recovery, Adams Behavioral Health stands as a reliable option for those in need of thorough and individualized rehabilitation assistance.

Adams Cnty Integrated Healthcare Servs

Adams Cnty Integrated Healthcare Servs, located in Othello, WA, specializes in extensive substance abuse recovery programs. This facility offers a variety of treatment options, including intensive outpatient and standard outpatient services. Emphasizing techniques such as 12-step programs, brief interventions, and cognitive behavioral therapy, the center provides personalized care tailored to the specific needs of each client. It also features dedicated programs for adolescents as well as adult men and women, accommodating a wide array of individuals. Catering to adults and seniors of every gender, the center fosters a nurturing atmosphere for healing. Adams Cnty Integrated Healthcare Servs is dedicated to providing exceptional support to help individuals attain long-term recovery.

Adams Recovery Center

Adams Recovery Center, located in Loveland, OH, features a wide array of evidence-based services for addiction treatment. This facility focuses on detoxification and support for substance use disorders, offering a variety of programs including intensive outpatient care, long-term residential stays, and outpatient options for adults and young adults. With an emphasis on cognitive behavioral therapy, relapse prevention strategies, and counseling for substance use disorders, the center effectively serves both men and women. The personalized programs designed for different client demographics ensure that each individual receives dedicated care and assistance. Adams Recovery Center is recognized for its dedication to providing high-quality care and a holistic approach to recovery.

Adams Recovery Center
New Richmond, OH

Adams Recovery Center, situated in New Richmond, OH, delivers comprehensive, science-backed therapies for those battling addiction. Their services include medical detox, structured outpatient care, extended stay residential treatment, and flexible outpatient options. Employing proven methods like cognitive behavioral therapy, relapse management, and addiction counseling, the center serves adult men, adult women, and young adults. By offering distinct programs for various demographics, Adams Recovery Center prioritizes personalized healing for enduring sobriety. Clients can anticipate thorough assistance and expert care from dedicated specialists at this respected recovery facility.

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Greensburg, KY

Adanta Group, located in Greensburg, KY, provides extensive outpatient services for both adults and children facing substance use issues, especially those with concurrent severe mental health challenges or emotional struggles. This center focuses on specific therapies, including anger management, cognitive behavioral therapy, and the Matrix Model, offering routine outpatient services alongside methadone/buprenorphine or naltrexone treatments. The programs are designed to support pregnant or postpartum women, as well as adults and seniors of all backgrounds. Emphasizing personalized treatment and proven methods, the center is dedicated to delivering top-notch care for individuals aiming to overcome addiction and mental health difficulties.

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Liberty, KY

The Adanta Group, situated in Liberty, KY, provides extensive outpatient services for individuals of all ages struggling with substance use disorders, including those with co-occurring mental health challenges. Employing proven therapeutic methods like cognitive behavioral therapy, anger management, and the Matrix Model, the center delivers individualized treatment plans. They uniquely support pregnant and postpartum women, demonstrating a dedication to diverse needs. Serving adult and senior men and women, the Adanta Group fosters a welcoming atmosphere. Clients can anticipate excellent care and customized support, whether they require standard outpatient services or specialized methadone/buprenorphine treatment.

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Campbellsville, KY

Adanta Group, located in Campbellsville, KY, specializes in outpatient treatment for adults dealing with substance use issues, particularly those with concurrent severe mental health conditions. They also extend their services to children experiencing significant emotional challenges. The center offers various treatment modalities, including outpatient programs involving methadone, buprenorphine, or naltrexone, alongside standard outpatient services to meet diverse patient requirements. By applying evidence-based methods such as cognitive behavioral therapy, anger management, and the Matrix Model, Adanta Group ensures an all-encompassing approach to treatment. Additionally, it features specialized programs for pregnant and postpartum women, distinguishing it from other facilities. The center serves adults and seniors of all gender identities, emphasizing personalized and high-quality rehabilitation care.

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Glasgow, KY

Adanta Group located in Glasgow, KY, specializes in outpatient care for adults and children facing substance abuse and concurrent mental health issues. The center employs various methodologies such as anger management, cognitive behavioral therapy, and the Matrix Model to customize treatment plans according to individual requirements. It also provides dedicated programs for pregnant or postpartum women, ensuring a wide range of support for different groups. Adanta Group serves adults and seniors of all genders and is committed to delivering high-quality, evidence-informed care to assist in the recovery process. Individuals in need of outpatient methadone or buprenorphine therapy, along with standard outpatient services, can receive tailored assistance at this center.

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Whitley City, KY

Situated in Whitley City, KY, the Adanta Group delivers targeted treatment for substance use issues alongside co-existing mental health challenges. This center provides outpatient care options, including treatments with methadone, buprenorphine, or naltrexone, customized for both adults and children. Utilizing evidence-based methodologies such as cognitive behavioral therapy, anger management, and the Matrix Model, the facility ensures thorough support. Importantly, the Adanta Group offers specific programs for women who are pregnant or in the postpartum phase and serves both male and female clients of all ages. Committed to high-quality and personalized treatment, this center stands as a vital resource for individuals on their recovery journey.

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Somerset, KY

Situated in Somerset, KY, the Adanta Group delivers targeted outpatient services for individuals battling substance abuse and concurrent severe mental health issues in adults, as well as significant emotional challenges in children. This center offers a range of treatment modalities, including outpatient methadone, buprenorphine, or naltrexone therapies, along with standard outpatient support. Emphasizing techniques such as anger management, cognitive behavioral therapy, and the Matrix Model, the facility customizes its services to meet each client's specific needs. Specialized programs for pregnant and postpartum women, together with resources available for adults and seniors across all genders, facilitate thorough and inclusive care. The Adanta Group is recognized for its exceptional treatment quality and varied therapeutic strategies.

Adanta Group
Monticello, KY

Situated in Monticello, KY, the Adanta Group delivers extensive outpatient services for adults dealing with substance use disorders alongside significant mental health challenges, as well as for children facing serious emotional difficulties. With expertise in areas such as anger management, cognitive behavioral therapy, and the Matrix Model, this center offers consistent outpatient treatment and medications like methadone, buprenorphine, or naltrexone. Tailored programs are available for pregnant and postpartum women, and the facility caters to adults and seniors across all genders. The Adanta Group is dedicated to providing high-quality care grounded in evidence-based practices to support individuals on their recovery journey.

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Jamestown, KY

The Adanta Group in Jamestown, KY, provides expert outpatient care for individuals of all ages struggling with substance use and related mental health conditions. This center prioritizes personalized treatment, offering options such as medication-assisted treatment with methadone, buprenorphine, or naltrexone, alongside routine outpatient counseling and dedicated support for pregnant and postpartum women. Employing proven therapeutic methods including anger management, cognitive behavioral therapy, and the Matrix Model, the Adanta Group serves a diverse clientele, from adults to seniors, across all genders. Its dedication to gender-sensitive services and customized recovery strategies makes it a leading destination for effective rehabilitation.

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Albany, KY

Adanta Group in Albany, KY, provides outpatient addiction services for adults and youth facing concurrent severe mental health conditions. Their specialized care includes programs for expectant and new mothers, incorporating techniques like anger management, cognitive behavioral therapy, and the Matrix Model. Patients can receive personalized outpatient care with methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Adanta Group, catering to individuals of all ages and genders, emphasizes personalized approaches and proven therapeutic strategies to deliver complete assistance for recovery.

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Columbia, KY

Adanta Group, located in Columbia, KY, provides dedicated outpatient services for individuals facing substance abuse issues and concurrent significant mental health disorders in adults, as well as severe emotional challenges in children. The center offers treatment options that include outpatient methadone, buprenorphine, or naltrexone, alongside standard outpatient services. Emphasizing techniques like anger management, cognitive behavioral therapy, and the Matrix Model, this facility customizes its approach to meet the unique needs of each client. Additionally, there are specialized programs available for pregnant and postpartum women to ensure thorough support. Adanta Group caters to adults and seniors regardless of gender, creating a nurturing setting for those in need of high-quality rehabilitation care.

ADAP Counseling Services
Port Saint Lucie, FL

ADAP Counseling Services located in Port Saint Lucie, FL, delivers outpatient treatment for substance use tailored to both adults and young adults. The center employs methods like cognitive-behavioral therapy, anger management, and motivational interviewing to create personalized care plans for each individual. With programs specifically designed for men and women, ADAP Counseling Services fosters a holistic and inclusive atmosphere for rehabilitation. Their commitment to high-quality care and individualized treatment options positions them as a significant asset for individuals looking for compassionate and effective support in overcoming addiction.

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ADAP Counseling Services in Stuart, FL, provides specialized outpatient addiction recovery programs for adults and adolescents. Employing evidence-based methods such as anger management, cognitive behavioral therapy, and motivational interviewing, the center delivers customized support to both male and female participants. ADAP Counseling Services prioritizes unique treatment trajectories, guaranteeing that every person gets the precise assistance required for their journey toward sobriety. The facility's dedication to superior care and bespoke recovery strategies makes it a noteworthy option for individuals pursuing impactful and thorough substance abuse treatment in the Stuart community.

ADAPT Addictions and Behavioral Health

ADAPT Addictions and Behavioral Health, located in Bismarck, ND, offers outpatient services specifically designed for adults and young adults facing substance use challenges. The facility emphasizes 12-step programs, anger management strategies, and short-term intervention techniques. It also has specialized offerings for individuals who have encountered intimate partner violence, domestic violence, trauma, and those dealing with both mental health issues and substance use problems. Committed to personalized treatment, ADAPT fosters a welcoming and supportive atmosphere for clients of all genders. For those seeking thorough and effective addiction support, this center is devoted to delivering high-quality care to aid in the recovery journey.

ADAPT Aware Zone Inc

ADAPT Aware Zone Inc, located in Whittier, CA, specializes in outpatient services for substance use treatment, particularly emphasizing Anger Management, Brief Intervention, and Contingency Management/Motivational Incentives. This center has dedicated programs for Active Duty Military members, as well as services for Adolescents and Adult Men. It offers assistance to both Adults and Children/Adolescents, ensuring that care is customized for individuals of all genders who are seeking support with addiction. With a strong dedication to high-quality treatment and evidence-based practices, ADAPT Aware Zone Inc stands out as a reliable option for those aiming to overcome substance use challenges in a compassionate outpatient environment.

Frequently Asked Questions

What is Medication-Assisted Treatment (MAT)?
MAT combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction treatment. Medications normalize brain chemistry, block euphoric effects of substances, relieve physiological cravings, and normalize body functions without negative effects of substance use. MAT is the gold standard for opioid and alcohol use disorders.
What medications are used in MAT?
For opioid use disorder: methadone, buprenorphine (Suboxone, Sublocade), and naltrexone (Vivitrol). For alcohol use disorder: naltrexone, acamprosate, and disulfiram. Each medication has unique benefits and considerations. A physician experienced in addiction medicine determines the most appropriate option based on individual circumstances, substance used, and treatment goals.
Is MAT just replacing one addiction with another?
No, this is a common misconception. MAT medications are prescribed at stable, therapeutic doses and don't produce euphoria when taken as directed. They're medicine, not substitution. MAT allows normal functioning, eliminates cravings, prevents withdrawal, dramatically reduces overdose risk, and enables engagement in therapy and rebuilding life. Research consistently shows MAT saves lives and improves outcomes.
How long does MAT last?
MAT duration varies by individual needs. Some people benefit from months of treatment, others years or indefinitely. There's no predetermined timeline. Research shows longer MAT duration improves outcomes and reduces overdose risk. Decisions about duration should be made collaboratively with healthcare providers based on stability, quality of life, and recovery goals, not arbitrary timelines.
Does insurance cover MAT?
Most health insurance plans cover MAT under mental health and substance use benefits. The Affordable Care Act and Mental Health Parity Act require coverage for addiction treatment including MAT. Coverage includes medications, office visits, counseling, and therapy. Contact your insurance provider or treatment center admissions to verify specific coverage and costs.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

Harm Reduction and Medication-Assisted Treatment

Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.

Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.

Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.

MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.

FDA-Approved Medications: Detailed Guides

The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.

Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.

Learn more about Naltrexone →

Buprenorphine (Suboxone)

Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.

Learn more about Buprenorphine →

Methadone

Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.

Learn more about Methadone →

Naloxone (Narcan)

Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.

Learn more about Naloxone →

MAT resources and information:

Find Medication-Assisted Treatment (MAT) by State

Browse medication-assisted treatment (mat) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)