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Medically Reviewed Content
Updated: May 2026
Sources: SAMHSA, NIDA

Medication-Assisted Treatment (MAT) Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction care. MAT is the gold standard for opioid and alcohol use disorders, significantly reducing overdose deaths and improving treatment outcomes.

Found 300 treatment centers offering medication-assisted treatment (mat) across the United States.

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Acenda Integrated Health

Acenda Integrated Health in Morristown, NJ, delivers a full spectrum of addiction recovery services designed for each person's unique journey. Their offerings include robust intensive outpatient programs, standard outpatient services, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The center utilizes proven therapeutic methods including motivational enhancement, cognitive restructuring, and rapid intervention to foster lasting sobriety. Specific treatment tracks are available for young people, adult men, and adult women, promoting a tailored approach to varied demographics. Acenda Integrated Health supports individuals of all ages and genders, providing high-caliber substance abuse care that prioritizes personalized and impactful outcomes.

Acenda Integrated Health

Acenda Integrated Health, located in Flemington, NJ, delivers personalized substance use recovery services. Their offerings include intensive outpatient treatment, standard outpatient care, and medication-assisted treatment options like methadone, buprenorphine, or naltrexone. The facility employs evidence-based approaches such as brief intervention, cognitive behavioral therapy, and motivational interviewing to foster healing. They provide specialized programs for adolescents, adult men, and adult women, with support extended to individuals and their children or adolescent family members. Acenda Integrated Health is committed to a welcoming and inclusive setting for individuals of all genders pursuing effective addiction treatment.

Achieve Wellness and Recovery

Situated in Northfield, NJ, Achieve Wellness and Recovery delivers extensive treatment for substance use for both adults and young adults. The facility offers various programs including intensive outpatient treatment, standard outpatient care, and outpatient day treatment, emphasizing methods such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. A distinguishing feature of this center is its personalized care approach, customizing treatment plans to fit the specific needs of each individual. Achieve Wellness and Recovery invites clients of all genders, fostering a welcoming and supportive atmosphere for those aiming for enduring recovery.

Achieve Whole Recovery
Colorado Springs, CO

Achieve Whole Recovery, situated in Colorado Springs, CO, delivers extensive outpatient programs for substance withdrawal, addiction recovery, and dual diagnoses in both adults and youth. This center features outpatient detox, methadone/buprenorphine therapies, and tailored support for those with significant mental health conditions. Their approach incorporates scientifically validated methods including 12-step guidance, motivational interviewing, and brief interventions to foster recovery. Tailoring treatment to each individual, Achieve Whole Recovery serves adults and elder individuals of any gender. Discover high-standard care and tailored assistance within a supportive setting aimed at holistic well-being.

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Corvallis, OR

Acme Counseling, located in Corvallis, OR, provides extensive services for individuals struggling with addiction and co-occurring psychological conditions, for both adults and young people. Their therapeutic offerings encompass intensive outpatient care, day treatment, and partial hospitalization programs. The center excels in techniques such as 12-step integration, anger management, and concise intervention strategies, and is equipped to support active military members, as well as adult men and women. Acme Counseling is committed to delivering personalized support and proven, research-backed methods to foster sustained recovery and overall mental wellness for all clients.

Acorn Counseling and Mediation Ltd

Acorn Counseling and Mediation Ltd, located in Carlinville, IL, specializes in providing targeted treatment for substance use issues among adults dealing with significant mental health difficulties, as well as children experiencing emotional challenges. Their offerings include outpatient services and day treatment options that feature 12-step support, anger management techniques, and brief therapeutic interventions. With a commitment to personalized care, they cater to men, women, and adolescents alike. This center prioritizes compassionate assistance, ensuring that both adults and younger clients receive support tailored to their specific situations. Acorn Counseling and Mediation Ltd is recognized for its holistic strategy in addressing co-occurring disorders and its dedication to delivering high-quality care to individuals across diverse backgrounds.

Acqua Recovery
Heber City, UT

Situated in Heber City, UT, Acqua Recovery delivers a wide array of research-backed treatment options for individuals grappling with substance use issues and related mental health challenges. The center offers intensive outpatient programs, outpatient day services, and partial hospitalization, employing various methodologies such as 12-step support, cognitive behavioral therapy, and strategies for anger management. Acqua Recovery is designed to serve different demographics, including active military members, adult males and females, as well as young adults. Prioritizing personalized care, this facility guarantees that clients receive tailored approaches that align with their distinct requirements. Whether individuals are in need of transitional housing, outpatient services, or sober living arrangements, Acqua Recovery fosters a nurturing atmosphere for sustainable recovery.

Acqua Recovery
Midway, UT

Situated in Midway, UT, Acqua Recovery provides a wide array of rehabilitation services aimed at adults and young adults who are on the path to recovery from substance use disorders. The center features detox programs, intensive outpatient care, and extended residential services, employing techniques like cognitive behavioral therapy and the 12-step program. Acqua Recovery has a particular focus on helping active duty military members, as well as adult men and women. Additionally, the facility offers transitional living arrangements and anger management assistance, ensuring personalized care for both genders and emphasizing the importance of maintaining long-term sobriety.

Acqua Recovery
Midway, UT

Nestled in Midway, UT, Acqua Recovery delivers extensive support for individuals battling addiction. This facility offers vital services including detoxification, comprehensive substance use care, and structured transitional and sober living arrangements for adult men and women. Patients can engage in treatment through flexible formats like intensive outpatient, extended residential stays, and standard outpatient programs, all designed to meet individual requirements. Acqua Recovery utilizes proven therapeutic methods such as 12-step integration, anger management techniques, and cognitive behavioral therapy. Specialized offerings are available for active military personnel, as well as adult men and women. Catering to both adults and young adults, Acqua Recovery is committed to providing high-quality, personalized treatment for sustainable recovery.

ACT/Counseling and Education

Situated in Scottsdale, Arizona, the ACT/Counseling and Education center provides extensive outpatient services addressing substance use, co-occurring disorders, and significant mental health issues in adults, as well as serious emotional disturbances in children. Employing proven techniques like 12-step facilitation, brief intervention, and cognitive behavioral therapy, this center has dedicated programs specifically designed for active duty military members, and both men and women. Catering to adults and young adults of all genders, the facility ensures high-quality, personalized care that meets individual needs, establishing itself as an essential option for those pursuing effective rehabilitation solutions.

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Action Consultants Therapy in Costa Mesa, CA, delivers outpatient care for individuals grappling with substance use disorders. Their expertise includes guiding clients through 12-step programs, teaching effective anger management techniques, and employing brief intervention strategies. This center is particularly adept at supporting those who have faced intimate partner or domestic violence. They provide individualized support for adults and young adults, recognizing the distinct needs of both men and women. Emphasizing a high standard of service and customized recovery plans, Action Consultants Therapy distinguishes itself through its specialized offerings and dedication to meeting the specific recovery journeys of every client.

Action Family Counseling

Nestled in Bakersfield, CA, Action Family Counseling delivers extensive treatment for substance use disorders affecting both adults and children who also face mental health challenges. The facility offers a range of services, including intensive outpatient programs, standard outpatient options, and day treatment, concentrating on methodologies such as 12-step facilitation, cognitive behavioral therapy, and brief interventions. Tailored programs are designed for active duty military personnel, adolescents, and men, guaranteeing customized care for each individual’s needs. Catering to both men and women, this center emphasizes high-quality care and employs evidence-based practices to foster enduring recovery. For those in search of effective and individualized addiction treatment, Action Family Counseling stands out as a reputable option.

Action Family Counseling
Santa Clarita, CA

Action Family Counseling, situated in Santa Clarita, CA, provides thorough care for substance misuse affecting adults and children, especially those with significant co-occurring mental health issues. Their services include intensive outpatient, outpatient, and day treatment, employing proven methods such as 12-step facilitation, cognitive behavioral therapy, and brief intervention. Specialized tracks are offered for active military personnel, teenagers, and adult men. Action Family Counseling serves both men and women, offering excellent support for those pursuing recovery from addiction and mental health struggles.

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Situated in Rochester, NY, "Action for a Better Community" delivers extensive treatment options for substance use issues and specialized support for those facing severe mental health challenges alongside addiction. The center features diverse outpatient programs, including treatments involving methadone and buprenorphine. Emphasizing approaches such as 12-step facilitation, anger management, and brief interventions, the facility serves adult males and females, alongside children and teenagers who have encountered intimate partner violence. "Action for a Better Community" is dedicated to providing customized services for all genders, guaranteeing effective care for individuals pursuing recovery from substance use disorders and mental health difficulties.

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Action for the Betterment of, situated in Sturgis, SD, delivers extensive care for substance abuse. Their services include outpatient and intensive outpatient programs, employing strategies like 12-step facilitation, motivational interviewing, and cognitive behavioral therapy. Dedicated programs are available for active military personnel, teens, adult men, adult women, older adults, and those in need of transitional living, sober living homes, or halfway house accommodations. This center prioritizes personalized support, offering a path to recovery within a supportive atmosphere.

Action Recovery Group

Action Recovery Group located in Ogden, UT, provides thorough treatment options for substance use targeting both adults and young adults. The center features intensive outpatient programs, standard outpatient services, as well as day treatment or partial hospitalization alternatives. Emphasizing methods such as 12-step support, anger management strategies, and brief intervention techniques, this facility addresses the specific requirements of active duty service members, as well as adult men and women. With tailored programs for each gender, the center commits to delivering personalized care and attention to all clients. Opt for Action Recovery Group for research-backed treatment and professional assistance in a friendly and nurturing atmosphere.

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Situated in Honolulu, HI, "Action with Aloha LLC" delivers a wide array of substance abuse treatment options for both adults and seniors. The center features intensive outpatient, outpatient, and standard outpatient programs that emphasize 12-step facilitation, management of anger, and brief intervention techniques. Tailored programs are available for adult men and women, along with those who have faced intimate partner or domestic violence. With a dedication to high-quality care, "Action with Aloha LLC" supports both male and female individuals seeking assistance for co-occurring substance use disorders and significant mental health challenges or emotional issues.

Active Recovery
Bossier City, LA

Situated in Bossier City, LA, Active Recovery specializes in intensive outpatient programs, outpatient services, and treatments involving methadone, buprenorphine, or naltrexone for substance abuse. The center employs techniques such as anger management, brief intervention, and cognitive behavioral therapy to create customized treatment plans for each client. Catering to adults and young adults of diverse backgrounds, Active Recovery is distinguished by its emphasis on individualized care. Its dedication to delivering high-quality and efficient treatment makes this facility a top option for individuals looking for focused addiction recovery support in a friendly and nurturing atmosphere.

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Centerville, UT

Situated in Centerville, UT, Active Recovery delivers a wide array of services aimed at assisting individuals in their journey toward overcoming addiction. This center focuses on treating substance use disorders, offering transitional housing and addressing the complexities of co-occurring substance use and significant mental health issues in adults, as well as serious emotional challenges in children. Active Recovery employs various treatment modalities, such as intensive outpatient care and day treatment programs. Their offerings include 12-step support, anger management techniques, and quick intervention strategies. The center is designed to meet the specific needs of active duty service members, as well as adult men and women, providing customized programs that cater to diverse requirements. Committed to delivering exceptional care, Active Recovery strives to help adults and young adults of all genders achieve sustainable recovery.

Active Recovery
Shreveport, LA

Situated in Shreveport, LA, Active Recovery provides extensive substance abuse rehabilitation for both adults and adolescents. This center offers a range of services including intensive outpatient programs, outpatient care, and specialized options for methadone/buprenorphine or naltrexone treatment. Emphasizing strategies such as anger management, brief intervention, and cognitive behavioral therapy, Active Recovery customizes its programs to meet the unique needs of each client. Additionally, the facility features gender-specific treatment options for men and women, ensuring a high standard of individualized care to aid in achieving long-lasting recovery.

Active Recovery
Minden, LA

Active Recovery in Minden, LA, provides specialized care for substance use disorders, offering intensive outpatient, outpatient, and medication-assisted treatment. The facility excels in anger management, brief intervention, and cognitive behavioral therapy. They have distinct programs designed for those impacted by intimate partner and domestic violence. Active Recovery supports adults and young adults across all genders, employing evidence-based practices for comprehensive recovery. Their dedication to high-quality, personalized treatment guides clients toward a life free from addiction.

Frequently Asked Questions

What is Medication-Assisted Treatment (MAT)?
MAT combines FDA-approved medications with counseling and behavioral therapies for comprehensive addiction treatment. Medications normalize brain chemistry, block euphoric effects of substances, relieve physiological cravings, and normalize body functions without negative effects of substance use. MAT is the gold standard for opioid and alcohol use disorders.
What medications are used in MAT?
For opioid use disorder: methadone, buprenorphine (Suboxone, Sublocade), and naltrexone (Vivitrol). For alcohol use disorder: naltrexone, acamprosate, and disulfiram. Each medication has unique benefits and considerations. A physician experienced in addiction medicine determines the most appropriate option based on individual circumstances, substance used, and treatment goals.
Is MAT just replacing one addiction with another?
No, this is a common misconception. MAT medications are prescribed at stable, therapeutic doses and don't produce euphoria when taken as directed. They're medicine, not substitution. MAT allows normal functioning, eliminates cravings, prevents withdrawal, dramatically reduces overdose risk, and enables engagement in therapy and rebuilding life. Research consistently shows MAT saves lives and improves outcomes.
How long does MAT last?
MAT duration varies by individual needs. Some people benefit from months of treatment, others years or indefinitely. There's no predetermined timeline. Research shows longer MAT duration improves outcomes and reduces overdose risk. Decisions about duration should be made collaboratively with healthcare providers based on stability, quality of life, and recovery goals, not arbitrary timelines.
Does insurance cover MAT?
Most health insurance plans cover MAT under mental health and substance use benefits. The Affordable Care Act and Mental Health Parity Act require coverage for addiction treatment including MAT. Coverage includes medications, office visits, counseling, and therapy. Contact your insurance provider or treatment center admissions to verify specific coverage and costs.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) represents the gold standard for treating opioid and alcohol use disorders. By combining FDA-approved medications with counseling and behavioral therapies, MAT addresses both the biological and psychological aspects of addiction. Research consistently demonstrates that MAT reduces overdose deaths by more than 50%, improves treatment retention, and supports long-term recovery.

MAT Medications for Opioid Use Disorder

Three FDA-approved medications treat opioid addiction:

  • Methadone: Full opioid agonist eliminating withdrawal and cravings; administered daily at certified opioid treatment programs (OTPs). Longest track record with extensive research supporting effectiveness.
  • Buprenorphine (Suboxone, Sublocade): Partial opioid agonist with ceiling effect, reducing abuse potential; prescribed by certified physicians in office settings or as monthly injection. Offers greater flexibility and privacy.
  • Naltrexone (Vivitrol): Opioid antagonist blocking opioid effects; requires complete detox before starting; available as daily pill or monthly injection. Best for motivated individuals after detox completion.

MAT for Alcohol Use Disorder

FDA-approved medications for alcohol addiction:

  • Naltrexone: Reduces cravings and blocks rewarding effects of alcohol; available as daily pill or monthly injection
  • Acamprosate (Campral): Helps restore brain chemistry balance; reduces cravings and supports abstinence
  • Disulfiram (Antabuse): Causes unpleasant reaction if alcohol consumed; provides deterrent for impulsive drinking

Comprehensive Treatment Approach

MAT is never medication alone. Quality programs integrate counseling, behavioral therapies, case management, recovery support services, treatment for co-occurring conditions, and peer support. The medication component allows individuals to engage fully in therapy and recovery activities by eliminating withdrawal, cravings, and physiological barriers to recovery.

Addressing Stigma and Misconceptions

MAT faces unfortunate stigma, with some viewing it as "replacing one drug with another." This is false. MAT medications are prescribed at stable therapeutic doses, don't produce euphoria, allow normal functioning, and are medicine treating a medical condition. Research overwhelming supports MAT as most effective treatment for opioid use disorder. Organizations like SAMHSA, NIDA, and medical professional societies strongly endorse MAT.

Finding MAT Treatment

Look for programs offering multiple MAT medication options, addiction medicine physicians, comprehensive counseling services, individualized treatment planning, support for long-term medication management, and evidence-based behavioral therapies. Our directory helps locate opioid treatment centers and programs offering MAT.

Harm Reduction and Medication-Assisted Treatment

Harm reduction is a public health philosophy that meets people where they are in their relationship with substance use. Rather than demanding abstinence as a precondition for support, harm reduction focuses on reducing the negative health, social, and economic consequences of drug use while keeping individuals alive, safe, and connected to care. This pragmatic approach recognizes that not everyone is ready or able to stop using substances immediately, and that incremental steps toward health are meaningful and worth supporting.

Harm reduction programs take many forms in communities across the country. Needle exchange and syringe service programs reduce the spread of HIV and hepatitis C among people who inject drugs. Naloxone (Narcan) distribution puts lifesaving overdose reversal medication directly into the hands of people who use drugs and their loved ones. Drug checking services, including fentanyl test strips, help people identify dangerous adulterants in their supply. Supervised consumption sites, operating in several countries and piloted in the United States, provide sterile environments with medical staff on hand to prevent fatal overdoses. Low-threshold MAT programs remove barriers to treatment by offering same-day starts, flexible scheduling, and minimal requirements for enrollment.

Harm reduction and abstinence are not competing philosophies — they are complementary approaches along a continuum of care. Many people who initially engage with harm reduction services eventually choose to pursue abstinence-based recovery. Research consistently shows that harm reduction programs serve as a critical bridge, connecting individuals to treatment they might never have accessed otherwise. Forcing a choice between the two creates a false dichotomy that costs lives.

MAT is itself a cornerstone harm reduction strategy. Buprenorphine and methadone maintenance programs dramatically reduce overdose deaths — studies show a 50% or greater reduction in all-cause mortality among patients receiving opioid agonist therapy. Beyond preventing fatal overdoses, MAT reduces HIV and hepatitis C transmission by decreasing injection drug use, lowers criminal activity and incarceration rates, and improves overall quality of life, housing stability, and employment outcomes. These benefits occur even when patients are not fully abstinent from all substances. By stabilizing brain chemistry and eliminating the desperate cycle of withdrawal and compulsive use, MAT gives people the stability they need to rebuild their lives. Facilities offering MAT as part of a harm reduction framework can be found through our opioid rehab directory.

FDA-Approved Medications: Detailed Guides

The U.S. Food and Drug Administration has approved several medications for the treatment of opioid and alcohol use disorders. Each works through a different mechanism and is suited to different clinical situations. Understanding the distinctions can help patients and families make informed decisions alongside their treatment providers. Explore our in-depth guides below.

Naltrexone (Vivitrol)

Naltrexone is an opioid antagonist that completely blocks the euphoric and sedative effects of opioids, removing the incentive to use. It is available as a daily oral pill or as a monthly extended-release injection marketed as Vivitrol. Because naltrexone requires a full detox period before initiation — typically 7 to 14 days opioid-free — it is best suited for patients who have already completed withdrawal management. Naltrexone is also FDA-approved for alcohol use disorder, where it reduces cravings and heavy drinking days.

Learn more about Naltrexone →

Buprenorphine (Suboxone)

Buprenorphine is a partial opioid agonist with a built-in ceiling effect, meaning its opioid effects plateau at moderate doses — significantly lowering the risk of respiratory depression and overdose. It is available as a sublingual film or tablet (commonly known by the brand name Suboxone, which also contains naloxone to deter misuse) and as a monthly subcutaneous injection (Sublocade). Buprenorphine can be prescribed in office-based settings by qualified providers, making it one of the most accessible MAT options. It effectively reduces cravings and withdrawal symptoms while carrying lower abuse potential than full agonists.

Learn more about Buprenorphine →

Methadone

Methadone is a full opioid agonist with more than 60 years of clinical evidence supporting its effectiveness. Administered daily at certified Opioid Treatment Programs (OTPs), methadone eliminates withdrawal symptoms, suppresses cravings, and blocks the effects of other opioids when dosed correctly. It is considered the most effective option for individuals with severe opioid use disorder, particularly those who have not responded to other medications. The structured program participation required — including regular clinic visits, counseling, and drug screening — provides an additional layer of accountability and support.

Learn more about Methadone →

Naloxone (Narcan)

Naloxone is an opioid antagonist used to rapidly reverse opioid overdoses. Available as a nasal spray (Narcan) and in injectable formulations, naloxone can restore normal breathing within minutes in a person experiencing respiratory depression from opioids. In 2023, Narcan nasal spray became available over the counter without a prescription, making it more accessible than ever. Every person who uses opioids, is prescribed high-dose opioid pain medication, or has a loved one at risk should keep naloxone on hand — it is safe, effective, and saves lives.

Learn more about Naloxone →

MAT resources and information:

Find Medication-Assisted Treatment (MAT) by State

Browse medication-assisted treatment (mat) programs in states with the most treatment options.

Explore Related Options

Related conditions, treatment approaches, and levels of care.

Medically Reviewed Updated May 2026

Reviewed by licensed addiction specialists. Information reflects current clinical guidance.

Sources:SAMHSA·NIDA·CDC

Need immediate help? Call SAMHSA: 1-800-662-4357 (24/7, free)